General Information of the Compound
Compound ID
CP0401970
Compound Name
(S)-4-(4-(3-methoxyazetidin-1-yl)-6-phenylpicolinamido)-5-oxo-5-(4-(pentyloxycarbonyl)piperazin-1-yl)pentanoic acid
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Structure
Formula
C31H41N5O7
Molecular Weight
595.697
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(cc(n1)-c1ccccc1)N1CC(C1)OC
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InChI
InChI=1S/C31H41N5O7/c1-3-4-8-17-43-31(41)35-15-13-34(14-16-35)30(40)25(11-12-28(37)38)33-29(39)27-19-23(36-20-24(21-36)42-2)18-26(32-27)22-9-6-5-7-10-22/h5-7,9-10,18-19,24-25H,3-4,8,11-17,20-21H2,1-2H3,(H,33,39)(H,37,38)/t25-/m0/s1
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InChIKey
IYVMXLDBNHAFQD-VWLOTQADSA-N
Physicochemical Property
logP
3.0178
Rotatable Bonds
13
Heavy Atom Count
43
Polar Areas
141.61
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
43

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46232945
ChEMBL ID
CHEMBL601486
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2 nM
   TI
   LI
   LO
   TS