General Information of the Compound
Compound ID
CP0494312
Compound Name
1-(4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)-3-methylbutan-1-one
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Structure
Formula
C17H24N4OS
Molecular Weight
332.473
Canonical SMILES
CCc1cc2c(ncnc2s1)N1CCN(CC1)C(=O)CC(C)C
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InChI
InChI=1S/C17H24N4OS/c1-4-13-10-14-16(18-11-19-17(14)23-13)21-7-5-20(6-8-21)15(22)9-12(2)3/h10-12H,4-9H2,1-3H3
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InChIKey
VXYVSOPLZPNDLE-UHFFFAOYSA-N
Physicochemical Property
logP
2.9484
Rotatable Bonds
4
Heavy Atom Count
23
Polar Areas
49.33
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 39073052
ChEMBL ID
CHEMBL566661
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2100 nM
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   LI
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