General Information of the Compound
Compound ID
CP0492725
Compound Name
(4S)5-Oxo-5-{4-[(pentyloxy)carbonyl]piperazin-1-yl}-4-[({6-phenyl-4-[(pyrrolidin-1-ylcarbonyl)oxy]pyridin-2-yl}carbonyl)amino]pentanoic Acid
    Show/Hide
Structure
Formula
C32H41N5O8
Molecular Weight
623.707
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OC(=O)N2CCCC2)cc(n1)-c1ccccc1
    Show/Hide
InChI
InChI=1S/C32H41N5O8/c1-2-3-9-20-44-31(42)37-18-16-35(17-19-37)30(41)25(12-13-28(38)39)34-29(40)27-22-24(45-32(43)36-14-7-8-15-36)21-26(33-27)23-10-5-4-6-11-23/h4-6,10-11,21-22,25H,2-3,7-9,12-20H2,1H3,(H,34,40)(H,38,39)/t25-/m0/s1
    Show/Hide
InChIKey
DJWUDYYFICUVCK-VWLOTQADSA-N
Physicochemical Property
logP
3.7774
Rotatable Bonds
12
Heavy Atom Count
45
Polar Areas
158.68
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
45

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 45140933
SID: 92390883
ChEMBL ID
CHEMBL591427
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 7.7 nM
   TI
   LI
   LO
   TS