General Information of the Compound
Compound ID
CP0384073
Compound Name
(4S)4-{[(4-{[1-(2-Methoxyethyl)piperidin-4-yl]oxy}-6-phenylpyridin-2-yl)carbonyl]amino}-5-oxo-5-{4-[(pentyloxy)carbonyl]-piperazin-1-yl}pentanoic Acid
    Show/Hide
Structure
Formula
C35H49N5O8
Molecular Weight
667.804
Canonical SMILES
CCCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OC2CCN(CCOC)CC2)cc(n1)-c1ccccc1
    Show/Hide
InChI
InChI=1S/C35H49N5O8/c1-3-4-8-22-47-35(45)40-19-17-39(18-20-40)34(44)29(11-12-32(41)42)37-33(43)31-25-28(24-30(36-31)26-9-6-5-7-10-26)48-27-13-15-38(16-14-27)21-23-46-2/h5-7,9-10,24-25,27,29H,3-4,8,11-23H2,1-2H3,(H,37,43)(H,41,42)/t29-/m0/s1
    Show/Hide
InChIKey
XURUYCRZVYGPAF-LJAQVGFWSA-N
Physicochemical Property
logP
3.6724
Rotatable Bonds
16
Heavy Atom Count
48
Polar Areas
150.84
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
48

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 45141774
SID: 92391744
ChEMBL ID
CHEMBL592886
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02449, P2Y purinoceptor 12
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 9.9 nM
   TI
   LI
   LO
   TS