| Compound ID |
Compound Name |
Compound Formula |
|
CP0898531
|
N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(6-methylpyridin-3-yl)-1H-indazol-6-yl)thio)propanamide
Show/Hide
|
C29H31F3N6OS
|
1
|
| 1 |
GI50 = 1 nM
|
|
|
|
CP0910643
|
N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(pyridin-4-yl)-1H-indazol-6-yl)thio)propanamide
Show/Hide
|
C28H29F3N6OS
|
1
|
| 1 |
GI50 = 1 nM
|
|
|
|
CP0928211
|
(E)-4-((4-Methylpiperazin-1-yl)methyl)-N-(3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propyl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C31H33F3N6OS
|
1
|
| 1 |
GI50 = 1 nM
|
|
|
|
CP0441015
|
N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]propanamide
Show/Hide
|
C30H31F3N6OS
|
1
|
| 1 |
GI50 = 2 nM
|
|
|
|
CP0911397
|
(E)-N-(4((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-4-yl)vinyl)-1H-indazol-6-yl)thio)propanamide
Show/Hide
|
C30H31F3N6OS
|
1
|
| 1 |
GI50 = 2 nM
|
|
|
|
CP0964873
|
N-[4-(4-Methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-3-[3-((E)-2-pyrazin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-propionamide
Show/Hide
|
C29H30F3N7OS
|
1
|
| 1 |
GI50 = 2 nM
|
|
|
|
CP0046394
|
BMS-907351
Show/Hide
|
C28H24FN3O5
|
2
|
| 1 |
GI50 = 3 nM
|
|
|
| 2 |
IC50 = 14 nM
|
|
|
|
CP0870201
|
N-[4-(4-Methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-N'-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-malonamide
Show/Hide
|
C30H30F3N7O2
|
1
|
| 1 |
GI50 = 4 nM
|
|
|
|
CP0946572
|
1-{4-Methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea
Show/Hide
|
C26H19F3N6OS
|
1
|
| 1 |
GI50 = 4 nM
|
|
|
|
CP0963126
|
N-{4-Methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-3-trifluoromethyl-benzamide
Show/Hide
|
C26H18F3N5OS
|
1
|
| 1 |
GI50 = 5 nM
|
|
|
|
CP0962729
|
N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(pyridin-3-yl)-1H-indazol-6-yl)thio)propanamide
Show/Hide
|
C28H29F3N6OS
|
1
|
| 1 |
GI50 = 9 nM
|
|
|
|
CP0964878
|
3-((3-Methyl-1H-indazol-6-yl)thio)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)propanamide
Show/Hide
|
C24H28F3N5OS
|
1
|
| 1 |
GI50 = 9 nM
|
|
|
|
CP0966460
|
2-(3-Chloro-phenyl)-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-acetamide
Show/Hide
|
C26H20ClN5OS
|
1
|
| 1 |
GI50 = 10 nM
|
|
|
|
CP0964277
|
4-(4-Methyl-piperazin-1-ylmethyl)-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-benzamide
Show/Hide
|
C31H31N7OS
|
1
|
| 1 |
GI50 = 12 nM
|
|
|
|
CP0869913
|
4-(4-Methyl-piperazin-1-ylmethyl)-N-{3-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-phenyl}-3-trifluoromethyl-benzamide
Show/Hide
|
C34H31F3N6OS
|
1
|
| 1 |
GI50 = 13 nM
|
|
|
|
CP0870202
|
N-{4-Methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-2-(3-trifluoromethyl-phenyl)-acetamide
Show/Hide
|
C27H20F3N5OS
|
1
|
| 1 |
GI50 = 13 nM
|
|
|
|
CP0910644
|
N-{4-Methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-2-naphthalen-1-yl-acetamide
Show/Hide
|
C30H23N5OS
|
1
|
| 1 |
GI50 = 15 nM
|
|
|
|
CP0946566
|
1-[4-(4-Methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-3-{3-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-phenyl}-urea
Show/Hide
|
C34H32F3N7OS
|
1
|
| 1 |
GI50 = 15 nM
|
|
|
|
CP0946568
|
2-(3,4-Dimethoxy-phenyl)-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-acetamide
Show/Hide
|
C28H25N5O3S
|
1
|
| 1 |
GI50 = 19 nM
|
|
|
|
CP0002211
|
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C22H27FN4O2
|
1
|
| 1 |
GI50 = 33 nM
|
|
|
|
CP0190068
|
N-[4-methyl-3-[1-(6-methylpyridine-3-carbonyl)piperidin-4-yl]oxyphenyl]-4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C33H38F3N5O3
|
1
|
| 1 |
GI50 = 35 nM
|
|
|
|
CP0898532
|
(E)-4-((4-Methylpiperazin-1-yl)methyl)-N-(2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)ethyl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H31F3N6OS
|
1
|
| 1 |
GI50 = 41 nM
|
|
|
|
CP0946570
|
(E)-1-(4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)ethyl)urea
Show/Hide
|
C30H32F3N7OS
|
1
|
| 1 |
GI50 = 42 nM
|
|
|
|
CP0855259
|
2-(4-(6,7-dimethoxyquinolin-4-yloxy)-2-methoxyphenyl)-N-(1-isopropyl-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C26H28N4O5
|
1
|
| 1 |
GI50 = 77 nM
|
|
|
|
CP0911398
|
2-[4-(2-Hydroxy-ethyl)-piperazin-1-yl]-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-acetamide
Show/Hide
|
C26H29N7O2S
|
1
|
| 1 |
GI50 = 81 nM
|
|
|
|
CP0851622
|
N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-2-(1-isopropyl-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C25H26N4O4
|
1
|
| 1 |
GI50 = 82 nM
|
|
|
|
CP0132005
|
2-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-N-(1-propan-2-ylpyrazol-4-yl)acetamide
Show/Hide
|
C24H25N5O4
|
1
|
| 1 |
GI50 = 93 nM
|
|
|
|
CP0964883
|
2-Amino-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-3-phenyl-propionamide
Show/Hide
|
C27H24N6OS
|
1
|
| 1 |
GI50 = 97 nM
|
|
|
|
CP0851621
|
Ripretinib
Show/Hide
|
C24H21BrFN5O2
|
1
|
| 1 |
GI50 = 98 nM
|
|
|
|
CP0898527
|
2-Amino-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-4-methylsulfanyl-butyramide
Show/Hide
|
C23H24N6OS2
|
1
|
| 1 |
GI50 = 101 nM
|
|
|
|
CP0043225
|
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H15ClF4N4O3
|
1
|
| 1 |
GI50 = 114 nM
|
|
|
|
CP0645833
|
(3S,8S,9S)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
Show/Hide
|
C19H24O7
|
1
|
| 1 |
GI50 = 140 nM
|
|
|
|
CP0946571
|
N-{4-Methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-isobutyramide
Show/Hide
|
C22H21N5OS
|
1
|
| 1 |
GI50 = 181 nM
|
|
|
|
CP0139586
|
(10S,12Z,15S,16R)-6,15,16-trihydroxy-4-methoxy-10-methyl-9-oxatricyclo[15.3.1.02,7]henicosa-1(21),2(7),3,5,12,17,19-heptaene-8,14-dione
Show/Hide
|
C22H22O7
|
1
|
| 1 |
GI50 = 290 nM
|
|
|
|
CP0898526
|
(E)-N-(4-methyl-5-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thiazol-2-yl)acetamide
Show/Hide
|
C20H17N5OS
|
1
|
| 1 |
GI50 = 301 nM
|
|
|
|
CP0902838
|
N-(4-((4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)nicotinamide
Show/Hide
|
C30H25N7O2
|
1
|
| 1 |
GI50 = 348 nM
|
|
|
|
CP0898530
|
N-{4-Methyl-5-[3-(1-methyl-1H-pyrazol-3-yl)-1H-indazol-6-yl]-thiazol-2-yl}-2-(4-methyl-piperazin-1-yl)-acetamide
Show/Hide
|
C22H26N8OS
|
1
|
| 1 |
GI50 = 351 nM
|
|
|
|
CP0946567
|
4-(4-Methyl-piperazin-1-ylmethyl)-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-thiazol-2-yl}-3-trifluoromethyl-benzamide
Show/Hide
|
C32H30F3N7OS2
|
1
|
| 1 |
GI50 = 376 nM
|
|
|
|
CP0263164
|
(10S,11E,15S,16R)-6,15,16-trihydroxy-4-methoxy-10-methyl-9-oxatricyclo[15.3.1.02,7]henicosa-1(21),2(7),3,5,11,17,19-heptaene-8,14-dione
Show/Hide
|
C22H22O7
|
1
|
| 1 |
GI50 = 420 nM
|
|
|
|
CP0864260
|
2-(4-(6,7-dimethoxyquinazolin-4-yloxy)-2-methoxyphenyl)-N-(1-isopropyl-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C25H27N5O5
|
1
|
| 1 |
GI50 = 442 nM
|
|
|
|
CP0558016
|
(10S,12Z,15S,16S)-6,15,16-trihydroxy-4-methoxy-10-methyl-9-oxatricyclo[15.3.1.02,7]henicosa-1(21),2(7),3,5,12,17,19-heptaene-8,14-dione
Show/Hide
|
C22H22O7
|
1
|
| 1 |
GI50 = 540 nM
|
|
|
|
CP0898533
|
2-(1-Methyl-piperidin-4-yl)-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-acetamide
Show/Hide
|
C26H28N6OS
|
1
|
| 1 |
GI50 = 570 nM
|
|
|
|
CP0855257
|
N-(4-((6,7-Dimethoxyquinazolin-4-yl)oxy)phenyl)-2-(4-isopropyl-1H-1,2,3-triazol-1-yl)acetamide
Show/Hide
|
C23H24N6O4
|
1
|
| 1 |
GI50 = 612 nM
|
|
|
|
CP0399068
|
2-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-N-(1-ethylpyrazol-4-yl)acetamide
Show/Hide
|
C23H23N5O4
|
1
|
| 1 |
GI50 = 680 nM
|
|
|
|
CP0887633
|
N-(5-((6,7-Dimethoxyquinolin-4-yl)oxy)pyridin-2-yl)-2-(1-isopropyl-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C24H25N5O4
|
1
|
| 1 |
GI50 = 761 nM
|
|
|
|
CP0891179
|
N-(4-((4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)phenyl)nicotinamide
Show/Hide
|
C29H23N7O2
|
1
|
| 1 |
GI50 = 882 nM
|
|
|
|
CP0869891
|
N-{4-Methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-2-piperidin-4-yl-acetamide
Show/Hide
|
C25H26N6OS
|
1
|
| 1 |
GI50 = 982 nM
|
|
|
|
CP0137907
|
2-(4-methylpiperazin-1-yl)-N-[4-methyl-5-[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]-1,3-thiazol-2-yl]acetamide
Show/Hide
|
C25H27N7OS
|
1
|
| 1 |
GI50 = 1180 nM
|
|
|
|
CP0851623
|
N-(4-((5,7-Dimethoxyquinazolin-4-yl)oxy)phenyl)-2-(4-isopropyl-1H-1,2,3-triazol-1-yl)acetamide
Show/Hide
|
C23H24N6O4
|
1
|
| 1 |
GI50 = 1222 nM
|
|
|
|
CP0394288
|
N-[4-[[5-fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino]phenyl]-2-(4-propan-2-yltriazol-1-yl)acetamide
Show/Hide
|
C24H26FN7O3
|
1
|
| 1 |
GI50 = 1378 nM
|
|
|
|
CP0249330
|
(10S,12Z)-6-hydroxy-4-methoxy-10-methyl-9-oxatricyclo[15.3.1.02,7]henicosa-1(20),2(7),3,5,12,17(21),18-heptaene-8,14-dione
Show/Hide
|
C22H22O5
|
1
|
| 1 |
GI50 = 1500 nM
|
|
|
|
CP0860664
|
N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(vinylsulfonamidomethyl)benzamide
Show/Hide
|
C26H24N6O3S
|
1
|
| 1 |
GI50 = 1560 nM
|
|
|
|
CP0854605
|
3-Acrylamido-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Show/Hide
|
C26H22N6O2
|
1
|
| 1 |
GI50 = 1570 nM
|
|
|
|
CP0893382
|
N-(4-((6,7-Dimethoxyquinazolin-4-yl)oxy)phenyl)-2-(1-ethyl-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C23H23N5O4
|
1
|
| 1 |
GI50 = 1615 nM
|
|
|
|
CP0965397
|
N-{5-[3-(3-Fluoro-phenyl)-1H-indazol-6-yl]-4-methyl-thiazol-2-yl}-2-(4-methyl-piperazin-1-yl)-acetamide
Show/Hide
|
C24H25FN6OS
|
1
|
| 1 |
GI50 = 1710 nM
|
|
|
|
CP0946569
|
2-(2-Methoxy-ethoxy)-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-acetamide
Show/Hide
|
C23H23N5O3S
|
1
|
| 1 |
GI50 = 1780 nM
|
|
|
|
CP0898529
|
N-{5-[3-(5-Fluoro-pyridin-3-yl)-1H-indazol-6-yl]-4-methyl-thiazol-2-yl}-2-(4-methyl-piperazin-1-yl)-acetamide
Show/Hide
|
C23H24FN7OS
|
1
|
| 1 |
GI50 = 1800 nM
|
|
|
|
CP0870205
|
N-{4-Methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-2-piperidin-3-yl-acetamide
Show/Hide
|
C25H26N6OS
|
1
|
| 1 |
GI50 = 1930 nM
|
|
|
|
CP0064831
|
US8586600, II-1
Show/Hide
|
C26H22N6O2
|
1
|
| 1 |
GI50 = 2030 nM
|
|
|
|
CP0911399
|
1-Methyl-piperidine-4-carboxylic acid {4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-amide
Show/Hide
|
C25H26N6OS
|
1
|
| 1 |
GI50 = 2040 nM
|
|
|
|
CP0864261
|
N-(4-((6,7-Dimethoxyquinazolin-4-yl)oxy)-2-methoxyphenyl)-2-(1-ethyl-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C24H25N5O5
|
1
|
| 1 |
GI50 = 2551 nM
|
|
|
|
CP0870207
|
N-(4-methyl-5-(3-(pyridin-3-yl)-1H-indazol-6-yl)thiazol-2-yl)-2-(4-methylpiperazin-1-yl)acetamide
Show/Hide
|
C23H25N7OS
|
1
|
| 1 |
GI50 = 2630 nM
|
|
|
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CP0192497
|
N-(1,3-dimethylpyrazol-4-yl)-2-[2-methoxy-4-(7-methoxyquinolin-4-yl)oxyphenyl]acetamide
Show/Hide
|
C24H24N4O4
|
1
|
| 1 |
GI50 = 2674 nM
|
|
|
|
CP0065824
|
3-(5-cyclopropyl-1,2-oxazol-3-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C14H16N6O
|
1
|
| 1 |
GI50 = 3000 nM
|
|
|
|
CP0139006
|
(10S,12Z,15R,16S)-6,15,16-trihydroxy-4-methoxy-10-methyl-9-oxatricyclo[15.3.1.02,7]henicosa-1(21),2(7),3,5,12,17,19-heptaene-8,14-dione
Show/Hide
|
C22H22O7
|
1
|
| 1 |
GI50 = 3000 nM
|
|
|
|
CP0898528
|
Piperidine-4-carboxylic acid {4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-yl]-thiazol-2-yl}-amide
Show/Hide
|
C24H24N6OS
|
1
|
| 1 |
GI50 = 3050 nM
|
|
|
|
CP0948271
|
N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-3-(propionamidomethyl)benzamide
Show/Hide
|
C27H26N6O2
|
1
|
| 1 |
GI50 = 3220 nM
|
|
|
|
CP0854595
|
3-Acrylamido-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-5-(trifluoromethyl)benzamide
Show/Hide
|
C27H21F3N6O2
|
1
|
| 1 |
GI50 = 3340 nM
|
|
|
|
CP0899400
|
N-(4-((4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)-2-(trifluoromethyl)benzyl)nicotinamide
Show/Hide
|
C31H24F3N7O2
|
1
|
| 1 |
GI50 = 3410 nM
|
|
|
|
CP0160345
|
2-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]-N-(1-propan-2-ylpyrazol-4-yl)acetamide
Show/Hide
|
C24H26N6O3
|
1
|
| 1 |
GI50 = 3595 nM
|
|
|
|
CP0893381
|
2-(5-(6,7-dimethoxyquinolin-4-yloxy)-3-methoxypyridin-2-yl)-N-(1-isopropyl-1H-pyrazol-4-yl)acetamide
Show/Hide
|
C25H27N5O5
|
1
|
| 1 |
GI50 = 3924 nM
|
|
|
|
CP0953406
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4-((N-(2-(Diethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
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C33H37N7O2
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1
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| 1 |
GI50 = 4550 nM
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CP0263163
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2-amino-1-ethyl-7-[(3R)-3-hydroxy-4-methoxy-3-methylbut-1-ynyl]-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide
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C18H22N4O4
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1
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| 1 |
GI50 = 4600 nM
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CP0941817
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4-((N-(2-(Dimethylamino)ethyl)butyramido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
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C32H37N7O2
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1
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| 1 |
GI50 = 4760 nM
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CP0883780
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4-(((2-(Dimethylamino)ethyl)amino)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Show/Hide
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C28H31N7O
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1
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| 1 |
GI50 = 4880 nM
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CP0410995
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US10807985, Compound 44
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C26H27FN10
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1
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| 1 |
GI50 = 4952 nM
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CP0139002
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(10S,15R,16S)-6,15,16-trihydroxy-4-methoxy-10-methyl-9-oxatricyclo[15.3.1.02,7]henicosa-1(21),2(7),3,5,17,19-hexaene-8,14-dione
Show/Hide
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C22H24O7
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1
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| 1 |
GI50 = 5100 nM
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CP0864256
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N-{4-[(5,7-Dimethoxyquinazolin-4-yl)amino]phenyl}-2-[4-(propan-2-yl)-1H-1,2,3-triazol-1-yl]acetamide
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C23H25N7O3
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1
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| 1 |
GI50 = 5408 nM
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CP0891184
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4-((N-(2-(Dimethylamino)ethyl)pivalamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
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C33H39N7O2
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1
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| 1 |
GI50 = 5480 nM
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CP0961918
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N-{5-[3-(2-Amino-pyrimidin-5-yl)-1H-indazol-6-yl]-4-methyl-thiazol-2-yl}-2-(4-methyl-piperazin-1-yl)-acetamide
Show/Hide
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C22H25N9OS
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1
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| 1 |
GI50 = 5630 nM
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CP0864071
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4-((N-Isopentylacrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
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C32H34N6O2
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1
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| 1 |
GI50 = 5740 nM
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CP0867480
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N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-propionamidobenzamide
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C26H24N6O2
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1
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| 1 |
GI50 = 6270 nM
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CP0855258
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2-(5-(6,7-dimethoxyquinazolin-4-yloxy)-3-methoxypyridin-2-yl)-N-(1-isopropyl-1H-pyrazol-4-yl)acetamide
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C24H26N6O5
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1
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| 1 |
GI50 = 8030 nM
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CP0891178
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(E)-4-((N-(2-(Dimethylamino)ethyl)but-2-enamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Show/Hide
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C32H35N7O2
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1
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| 1 |
GI50 = 8540 nM
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CP0911799
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4-((N-(2-(Dimethylamino)ethyl)isobutyramido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
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C32H37N7O2
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1
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| 1 |
GI50 = 8640 nM
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CP0002778
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4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Show/Hide
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C29H31N7O
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1
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| 1 |
GI50 > 10000 nM
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CP0864259
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N-{4-[(5-Fluoro-7-methoxyquinazolin-4-yl)amino]phenyl}-2-[4-(propan-2-yl)-1H-1,2,3-triazol-1-yl]acetamide
Show/Hide
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C22H22FN7O2
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1
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| 1 |
GI50 > 10000 nM
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CP0080859
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N-[2-(dimethylamino)ethyl]-N-[[4-[[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]methyl]pyridine-3-carboxamide
Show/Hide
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C34H34N8O2
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1
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| 1 |
GI50 > 10000 nM
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CP0218115
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US8586600, II-6
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C27H24N6O2
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1
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| 1 |
GI50 > 10000 nM
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CP0867481
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N-(2-Hydroxyethyl)-N-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)nicotinamide
Show/Hide
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C32H29N7O3
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1
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| 1 |
GI50 > 10000 nM
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CP0867482
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N-(2-(Dimethylamino)ethyl)-N-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)isoxazole-5-carboxamide
Show/Hide
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C32H32N8O3
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1
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| 1 |
GI50 > 10000 nM
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CP0874420
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4-((2-(Dimethylamino)-N-(2-(dimethylamino)ethyl)acetamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Show/Hide
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C32H38N8O2
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1
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| 1 |
GI50 > 10000 nM
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CP0875440
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N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(propionamidomethyl)benzamide
Show/Hide
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C27H26N6O2
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1
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| 1 |
GI50 > 10000 nM
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CP0875470
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N-(4-((4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)-N-(2-(pyrrolidin-1-yl)ethyl)nicotinamide
Show/Hide
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C36H36N8O2
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1
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| 1 |
GI50 > 10000 nM
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CP0887639
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N-(2-(Dimethylamino)ethyl)-N-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)thiophene-2-carboxamide
Show/Hide
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C33H33N7O2S
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1
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| 1 |
GI50 > 10000 nM
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CP0891169
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4-((N-(2-(Dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Show/Hide
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C31H33N7O2
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1
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| 1 |
GI50 > 10000 nM
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CP0899397
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3-(Acrylamidomethyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Show/Hide
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C27H24N6O2
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1
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| 1 |
GI50 > 10000 nM
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CP0899399
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4-((2-(Dimethylamino)-N-(2-hydroxyethyl)acetamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Show/Hide
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C30H33N7O3
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1
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| 1 |
GI50 > 10000 nM
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CP0899401
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N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-3-propionamido-5-(trifluoromethyl)benzamide
Show/Hide
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C27H23F3N6O2
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1
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| 1 |
GI50 > 10000 nM
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CP0906649
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N-(2-(Diethylamino)ethyl)-N-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)nicotinamide
Show/Hide
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C36H38N8O2
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1
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| 1 |
GI50 > 10000 nM
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CP0906653
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4-(Acrylamidomethyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-3-(trifluoromethyl)benzamide
Show/Hide
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C28H23F3N6O2
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1
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| 1 |
GI50 > 10000 nM
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CP0911792
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4-((N-(2-(Dimethylamino)ethyl)cyclopropanecarboxamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Show/Hide
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C32H35N7O2
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1
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| 1 |
GI50 > 10000 nM
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CP0942328
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4-((N-(2-(Dimethylamino)ethyl)propionamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Show/Hide
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C31H35N7O2
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1
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| 1 |
GI50 > 10000 nM
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CP0955464
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N-(2-(Dimethylamino)ethyl)-4-methyl-N-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)benzamide
Show/Hide
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C36H37N7O2
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1
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| 1 |
GI50 > 10000 nM
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CP0165545
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(10S,12Z,15R,16R)-6,15,16-trihydroxy-4-methoxy-10-methyl-14-methylidene-9-oxatricyclo[15.3.1.02,7]henicosa-1(21),2(7),3,5,12,17,19-heptaen-8-one
Show/Hide
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C23H24O6
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1
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| 1 |
GI50 > 25000 nM
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CP0202493
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(10S,12Z,14R,15R,16R)-6,14,15,16-tetrahydroxy-4-methoxy-10-methyl-9-oxatricyclo[15.3.1.02,7]henicosa-1(21),2(7),3,5,12,17,19-heptaen-8-one
Show/Hide
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C22H24O7
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1
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| 1 |
GI50 > 25000 nM
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CP0202494
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(10S,12Z,14S,15R,16R)-14-amino-6,15,16-trihydroxy-4-methoxy-10-methyl-9-oxatricyclo[15.3.1.02,7]henicosa-1(21),2(7),3,5,12,17,19-heptaen-8-one
Show/Hide
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C22H25NO6
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1
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| 1 |
GI50 > 25000 nM
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CP0356481
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(10S,15S,16R)-6,15,16-trihydroxy-4-methoxy-10-methyl-9-oxatricyclo[15.3.1.02,7]henicosa-1(21),2(7),3,5,17,19-hexaene-8,14-dione
Show/Hide
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C22H24O7
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1
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| 1 |
GI50 > 25000 nM
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CP0531968
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(10S,15S,16S)-6,15,16-trihydroxy-4-methoxy-10-methyl-9-oxatricyclo[15.3.1.02,7]henicosa-1(21),2(7),3,5,17,19-hexaene-8,14-dione
Show/Hide
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C22H24O7
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1
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| 1 |
GI50 > 25000 nM
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CP0474375
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5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-[3-(trifluoromethyl)phenyl]indole-1-carboxamide
Show/Hide
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C22H16F3N5O2
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1
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| 1 |
IC50 = 0.4 nM
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CP0200223
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5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-[5-(1-methylcyclopropyl)-1H-pyrazol-3-yl]indole-1-carboxamide
Show/Hide
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C22H21N7O2
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1
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| 1 |
IC50 = 0.5 nM
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CP0520957
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5-[[(6S)-7-acetyl-6-methyl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]oxy]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]indole-1-carboxamide
Show/Hide
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C26H23F3N6O4
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1
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| 1 |
IC50 = 0.7 nM
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CP0107422
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N-[5-(1-methylcyclopropyl)-1H-pyrazol-3-yl]-5-[[(6S)-6-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]oxy]indole-1-carboxamide
Show/Hide
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C24H25N7O2
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1
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| 1 |
IC50 = 0.9 nM
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CP0234882
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N-[5-(1-methylcyclopropyl)-1H-pyrazol-3-yl]-5-[[(6R)-6-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]oxy]indole-1-carboxamide
Show/Hide
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C24H25N7O2
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1
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| 1 |
IC50 = 0.9 nM
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CP0054974
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N-(5-tert-butyl-1H-pyrazol-3-yl)-5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C23H25N7O2
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1
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| 1 |
IC50 = 1 nM
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CP0112799
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5-[[(6S)-6-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]oxy]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]indole-1-carboxamide
Show/Hide
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C24H21F3N6O3
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2
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| 1 |
IC50 = 1 nM
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| 2 |
IC50 = 2 nM
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CP0452456
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N-(5-tert-butyl-1H-pyrazol-3-yl)-5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C22H23N7O2
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1
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| 1 |
IC50 = 1 nM
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CP0190088
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5-[[(6S)-7-acetyl-6-methyl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]oxy]-N-(5-cyclopropyl-1,2-oxazol-3-yl)indole-1-carboxamide
Show/Hide
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C25H24N6O4
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1
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| 1 |
IC50 = 1.3 nM
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CP0555562
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6-[6-(hydroxymethyl)pyrimidin-4-yl]oxy-N-[3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide
Show/Hide
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C23H16F3N3O3
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1
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| 1 |
IC50 = 1.3 nM
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CP0575674
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6-(2-aminopyrimidin-4-yl)oxy-N-[3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide
Show/Hide
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C22H15F3N4O2
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1
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| 1 |
IC50 = 1.7 nM
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CP0388837
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5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-(5-propan-2-yl-1,2-oxazol-3-yl)indole-1-carboxamide
Show/Hide
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C21H20N6O3
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2
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| 1 |
IC50 = 2 nM
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| 2 |
IC50 = 4.1 nM
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CP0555561
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5-[6-(methylaminomethyl)pyrimidin-4-yl]oxy-N-[5-(1-methylcyclopropyl)-1H-pyrazol-3-yl]indole-1-carboxamide
Show/Hide
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C22H23N7O2
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1
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| 1 |
IC50 = 2 nM
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CP0520958
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5-[(7-acetyl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl)oxy]-N-(5-cyclopropyl-1,2-oxazol-3-yl)indole-1-carboxamide
Show/Hide
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C24H22N6O4
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1
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| 1 |
IC50 = 2.1 nM
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CP0234883
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N-[5-(1-methylcyclopropyl)-1H-pyrazol-3-yl]-5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C23H23N7O2
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2
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| 1 |
IC50 = 2.3 nM
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| 2 |
IC50 = 3 nM
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CP0451475
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5-[6-(methylaminomethyl)pyrimidin-4-yl]oxy-N-[5-[1-(trifluoromethyl)cyclopropyl]-1H-pyrazol-3-yl]indole-1-carboxamide
Show/Hide
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C22H20F3N7O2
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1
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| 1 |
IC50 = 2.5 nM
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CP0520953
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5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-[5-(1-hydroxy-2-methylpropan-2-yl)-1,2-oxazol-3-yl]indole-1-carboxamide
Show/Hide
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C22H22N6O4
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1
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| 1 |
IC50 = 2.5 nM
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CP0451473
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5-[6-(methylaminomethyl)pyrimidin-4-yl]oxy-N-(5-propan-2-yl-1H-pyrazol-3-yl)indole-1-carboxamide
Show/Hide
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C21H23N7O2
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1
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| 1 |
IC50 = 2.8 nM
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CP0230994
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N-(5-propan-2-yl-1H-pyrazol-3-yl)-5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C22H23N7O2
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1
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| 1 |
IC50 = 3 nM
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CP0174788
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N-(5-tert-butyl-1,2-oxazol-3-yl)-6-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C22H22N6O3
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1
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| 1 |
IC50 = 3 nM
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CP0107421
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N-(5-tert-butyl-1,2-oxazol-3-yl)-5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C22H22N6O3
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3
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| 1 |
IC50 = 3 nM
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| 2 |
IC50 = 59 nM
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| 3 |
IC50 = 59.4 nM
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CP0309083
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N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-5-tert-butylthiophene-2-carboxamide
Show/Hide
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C27H27N7OS
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1
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| 1 |
IC50 = 4 nM
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CP0200227
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5-[6-(hydroxymethyl)pyrimidin-4-yl]oxy-N-[3-(trifluoromethyl)phenyl]indole-1-carboxamide
Show/Hide
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C21H15F3N4O3
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1
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| 1 |
IC50 = 4 nM
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CP0200232
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N-(5-tert-butyl-1,2-oxazol-3-yl)-5-[[(6S)-6-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]oxy]indole-1-carboxamide
Show/Hide
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C24H26N6O3
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1
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| 1 |
IC50 = 4 nM
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CP0561089
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N-(5-cyclopropyl-1,2-oxazol-3-yl)-5-(5,7-dihydrothieno[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C21H17N5O3S
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1
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| 1 |
IC50 = 4.1 nM
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CP0147359
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N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-3-(4-ethylpiperazin-1-yl)-5-(trifluoromethyl)benzamide
Show/Hide
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C32H32F3N9O
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1
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| 1 |
IC50 = 5 nM
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CP0451480
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5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]indole-1-carboxamide
Show/Hide
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C22H17F3N6O3
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1
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| 1 |
IC50 = 5 nM
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CP0465207
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5-[6-(methylaminomethyl)pyrimidin-4-yl]oxy-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]indole-1-carboxamide
Show/Hide
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C22H19F3N6O3
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1
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| 1 |
IC50 = 5.8 nM
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CP0065280
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5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-[5-(1-methylcyclopropyl)-1,2-oxazol-3-yl]indole-1-carboxamide
Show/Hide
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C22H20N6O3
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2
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| 1 |
IC50 = 6 nM
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| 2 |
IC50 = 6.2 nM
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CP0520952
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N-(5-cyclopropyl-1,2-oxazol-3-yl)-5-[(7-ethyl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl)oxy]indole-1-carboxamide
Show/Hide
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C24H24N6O3
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1
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| 1 |
IC50 = 7.9 nM
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CP0127137
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N-(5-tert-butyl-1,2-oxazol-3-yl)-5-[[(5S)-5-methyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yl]oxy]indole-1-carboxamide
Show/Hide
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C23H24N6O3
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1
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| 1 |
IC50 = 8 nM
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CP0482870
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N-(5-cyclopropyl-1,2-oxazol-3-yl)-5-[6-(hydroxymethyl)pyrimidin-4-yl]oxyindole-1-carboxamide
Show/Hide
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C20H17N5O4
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1
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| 1 |
IC50 = 8.8 nM
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CP0570772
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5-[6-(methylaminomethyl)pyrimidin-4-yl]oxy-N-[5-(1-methylcyclopropyl)-1,2-oxazol-3-yl]indole-1-carboxamide
Show/Hide
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C22H22N6O3
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1
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| 1 |
IC50 = 9.4 nM
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CP0186358
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5-[(6,7-dimethoxyquinazolin-4-yl)amino]-4-fluoro-2-methylphenol
Show/Hide
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C17H16FN3O3
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1
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| 1 |
IC50 = 9.5 nM
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CP0081362
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4-fluoro-2-[5-[[(1R)-2-hydroxy-1-phenylethyl]amino]-3-(3-methyl-2H-indazol-5-yl)pyridin-2-yl]phenol
Show/Hide
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C27H23FN4O2
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1
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| 1 |
IC50 = 9.8 nM
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CP0223528
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5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)-N-[3-(trifluoromethyl)phenyl]indole-1-carboxamide
Show/Hide
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C23H18F3N5O2
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1
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| 1 |
IC50 = 10 nM
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CP0420472
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5-[(7-ethyl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl)oxy]-N-[3-(trifluoromethyl)phenyl]indole-1-carboxamide
Show/Hide
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C25H22F3N5O2
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1
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| 1 |
IC50 = 10 nM
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CP0465206
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5-[(6-acetyl-5,7-dihydropyrrolo[3,4-d]pyrimidin-4-yl)oxy]-N-(5-cyclopropyl-1,2-oxazol-3-yl)indole-1-carboxamide
Show/Hide
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C23H20N6O4
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1
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| 1 |
IC50 = 10.1 nM
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CP0127132
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5-[6-(methylaminomethyl)pyrimidin-4-yl]oxy-N-[3-(trifluoromethyl)phenyl]indole-1-carboxamide
Show/Hide
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C22H18F3N5O2
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2
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| 1 |
IC50 = 11 nM
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| 2 |
IC50 = 11.2 nM
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CP0475328
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N-(5-cyclopropyl-1,2-oxazol-3-yl)-5-[6-(tetrazol-2-ylmethyl)pyrimidin-4-yl]oxyindole-1-carboxamide
Show/Hide
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C21H17N9O3
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1
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| 1 |
IC50 = 12.8 nM
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CP0570774
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5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-[5-(oxan-4-yl)-1,2-oxazol-3-yl]indole-1-carboxamide
Show/Hide
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C23H22N6O4
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1
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| 1 |
IC50 = 12.8 nM
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CP0309066
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3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-isopropylphenyl)-4-methylbenzamide
Show/Hide
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C28H27N7O
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1
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| 1 |
IC50 = 17 nM
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CP0236458
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5-[6-(methylaminomethyl)pyrimidin-4-yl]oxy-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]indole-1-carboxamide
Show/Hide
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C20H18F3N7O2
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1
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| 1 |
IC50 = 17.4 nM
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CP0451479
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5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-[5-[1-(hydroxymethyl)cyclopropyl]-1,2-oxazol-3-yl]indole-1-carboxamide
Show/Hide
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C22H20N6O4
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1
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| 1 |
IC50 = 17.9 nM
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CP0166378
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3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
Show/Hide
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C30H24F3N9O
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1
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| 1 |
IC50 = 20 nM
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CP0132915
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N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]acetamide
Show/Hide
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C19H22N6O3
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1
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| 1 |
IC50 = 24 nM
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CP0702407
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N-(2,6-Difluoro-3,5-dimethoxyphenyl)-N'-(1-methylethyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
Show/Hide
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C25H28F2N6O2
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2
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| 1 |
IC50 = 24.55 nM
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| 2 |
IC50 > 10000 nM
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CP0520951
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5-[6-(methylaminomethyl)pyrimidin-4-yl]oxy-N-(5-propan-2-yl-1,2-oxazol-3-yl)indole-1-carboxamide
Show/Hide
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C21H22N6O3
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1
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| 1 |
IC50 = 25.2 nM
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CP0107456
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N-(5-cyclopropyl-1,2-oxazol-3-yl)-5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C21H18N6O3
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1
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| 1 |
IC50 = 26 nM
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CP0388620
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methyl N-[4-[7-amino-3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxypyrazolo[1,5-a]pyrimidin-6-yl]phenyl]carbamate
Show/Hide
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C28H32N6O5
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1
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| 1 |
IC50 = 26 nM
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CP0150295
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N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-3-chloro-4-[(4-ethylpiperazin-1-yl)methyl]benzamide
Show/Hide
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C32H34ClN9O
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1
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| 1 |
IC50 = 30 nM
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CP0191647
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N-(5-tert-butyl-1,2-oxazol-3-yl)-5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)pyrrolo[3,2-b]pyridine-1-carboxamide
Show/Hide
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C21H21N7O3
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1
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| 1 |
IC50 = 33 nM
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CP0166375
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N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
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C26H20F3N7O
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1
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| 1 |
IC50 = 36 nM
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CP0305155
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N-(5-tert-butyl-1,2-oxazol-3-yl)-5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)pyrrolo[2,3-b]pyridine-1-carboxamide
Show/Hide
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C21H21N7O3
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1
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| 1 |
IC50 = 36 nM
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CP0065278
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N-(5-tert-butyl-1,2-oxazol-3-yl)-5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C23H24N6O3
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1
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| 1 |
IC50 = 40 nM
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CP0147351
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N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzamide
Show/Hide
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C31H30F3N9O
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1
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| 1 |
IC50 = 43 nM
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CP0464293
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N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]cyclopropanecarboxamide
Show/Hide
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C21H24N6O3
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1
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| 1 |
IC50 = 43 nM
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CP0166376
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N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-5-cyclopropyl-1H-pyrazole-3-carboxamide
Show/Hide
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C25H23N9O
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1
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| 1 |
IC50 = 48 nM
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CP0174789
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6-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-[5-(1-methylcyclopropyl)-1H-pyrazol-3-yl]indolizine-1-carboxamide
Show/Hide
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C22H21N7O2
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1
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| 1 |
IC50 = 51 nM
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CP0147352
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3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-tert-butylphenyl)-4-methylbenzamide
Show/Hide
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C29H29N7O
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1
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| 1 |
IC50 = 52 nM
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CP0136623
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3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide
Show/Hide
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C26H20F3N7O
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1
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| 1 |
IC50 = 55 nM
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CP0305156
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N-(5-tert-butyl-1,2-oxazol-3-yl)-6-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)pyrrolo[3,2-b]pyridine-1-carboxamide
Show/Hide
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C21H21N7O3
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1
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| 1 |
IC50 = 55 nM
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CP0061016
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3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-phenol
Show/Hide
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C17H18N4O
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1
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| 1 |
IC50 = 58 nM
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CP0200225
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5-[[(6S)-6-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]oxy]-N-[3-(trifluoromethyl)phenyl]indole-1-carboxamide
Show/Hide
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C24H20F3N5O2
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1
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| 1 |
IC50 = 60 nM
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CP0289191
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N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-1-tert-butyl-5-[(4-methylpiperazin-1-yl)methyl]pyrazole-3-carboxamide
Show/Hide
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C32H39N11O
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1
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| 1 |
IC50 = 63 nM
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CP0230192
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N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-3-(1-methylpiperidin-4-yl)oxy-5-(trifluoromethyl)benzamide
Show/Hide
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C32H31F3N8O2
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1
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| 1 |
IC50 = 66 nM
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CP0054953
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N-[4-fluoro-3-(trifluoromethyl)phenyl]-5-[6-(methylaminomethyl)pyrimidin-4-yl]oxyindole-1-carboxamide
Show/Hide
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C22H17F4N5O2
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1
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| 1 |
IC50 = 66 nM
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CP0391617
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5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,4-difluorophenol
Show/Hide
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C16H13F2N3O3
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1
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| 1 |
IC50 = 66 nM
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CP0570773
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N-(5-cyclopropyl-1,2-oxazol-3-yl)-5-[[(6R)-6-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]oxy]indole-1-carboxamide
Show/Hide
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C23H22N6O3
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1
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| 1 |
IC50 = 66 nM
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CP0112800
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N-(5-tert-butyl-1,2-oxazol-3-yl)-7-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)imidazo[1,2-a]pyridine-3-carboxamide
Show/Hide
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C21H21N7O3
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1
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| 1 |
IC50 = 78 nM
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CP0388838
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5-(5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yloxy)-N-[3-(trifluoromethyl)phenyl]indole-1-carboxamide
Show/Hide
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C23H18F3N5O2
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1
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| 1 |
IC50 = 81 nM
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CP0270477
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5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenol
Show/Hide
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C17H17N3O3
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1
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| 1 |
IC50 = 88 nM
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CP0475329
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N-(5-cyclopropyl-1,2-oxazol-3-yl)-5-[[(6S)-6-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]oxy]indole-1-carboxamide
Show/Hide
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C23H22N6O3
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1
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| 1 |
IC50 = 89 nM
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CP0672788
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(S)-N-((1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-yl)methyl)-1,1,1-trifluoromethanesulfonamide
Show/Hide
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C29H34F3N7O4S
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2
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| 1 |
IC50 = 89.13 nM
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| 2 |
IC50 > 10000 nM
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CP0230191
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3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-(difluoromethoxy)phenyl)-4-methylbenzamide
Show/Hide
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C26H21F2N7O2
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1
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| 1 |
IC50 = 92 nM
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CP0558352
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3-[(6,7-dimethoxyquinazolin-4-yl)amino]-4-fluorophenol
Show/Hide
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C16H14FN3O3
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1
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| 1 |
IC50 = 98 nM
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CP0538451
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5-[[(6R)-6-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]oxy]-N-[3-(trifluoromethyl)phenyl]indole-1-carboxamide
Show/Hide
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C24H20F3N5O2
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1
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| 1 |
IC50 = 109 nM
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CP0692220
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N1-(2-chloro-3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
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C25H30Cl2N6O2
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2
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| 1 |
IC50 = 109.65 nM
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| 2 |
IC50 > 10000 nM
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CP0424847
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2-chloro-5-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Show/Hide
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C16H14ClN3O3
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1
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| 1 |
IC50 = 110 nM
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CP0702106
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3-((3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(2-(isopropylamino)ethyl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
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C28H35N7O2
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2
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| 1 |
IC50 = 114.82 nM
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| 2 |
IC50 > 10000 nM
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CP0278790
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4-methyl-3-(1-(6-(3-(4-methylpiperazin-1-yl)propylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide
Show/Hide
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C34H36F3N9O
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1
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| 1 |
IC50 = 117 nM
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CP0127130
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5-[[(5S)-5-methyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yl]oxy]-N-[3-(trifluoromethyl)phenyl]indole-1-carboxamide
Show/Hide
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C23H18F3N5O2
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1
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| 1 |
IC50 = 118 nM
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CP0147357
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4-methyl-3-(1-(4-(3-(4-methylpiperazin-1-yl)propylamino)-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide
Show/Hide
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C33H35F3N10O
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1
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| 1 |
IC50 = 133 nM
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CP0121992
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6-[[(6S)-6-methyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]oxy]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]indole-1-carboxamide
Show/Hide
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C24H21F3N6O3
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1
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| 1 |
IC50 = 134 nM
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CP0786852
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2-((2,6-difluoro-3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
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C22H21F2N5O3
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2
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| 1 |
IC50 = 134.9 nM
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| 2 |
IC50 > 10000 nM
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CP0166279
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3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(2-methylpyridin-4-yl)benzamide
Show/Hide
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C25H22N8O
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1
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| 1 |
IC50 = 135 nM
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CP0418567
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3-[4-amino-7-[3-(hydroxymethyl)cyclobutyl]pyrrolo[2,3-d]pyrimidin-5-yl]phenol
Show/Hide
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C17H18N4O2
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1
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| 1 |
IC50 = 150 nM
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CP0200222
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N-(3-tert-butyl-1,2-oxazol-5-yl)-5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C22H22N6O3
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1
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| 1 |
IC50 = 167 nM
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CP0744817
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1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)azetidin-3-ol
Show/Hide
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C26H30N6O3
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2
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| 1 |
IC50 = 177.83 nM
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| 2 |
IC50 > 10000 nM
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CP0773263
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N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)methanesulfonamide
Show/Hide
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C23H26N6O4S
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2
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| 1 |
IC50 = 177.83 nM
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| 2 |
IC50 > 10000 nM
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CP0150292
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4-methyl-3-(1-(6-(2-(4-methylpiperazin-1-yl)ethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide
Show/Hide
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C33H34F3N9O
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1
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| 1 |
IC50 = 185 nM
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CP0734013
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7-[N-[2-(dimethylsulfamoylamino)ethyl]-3,5-dimethoxy-anilino]-2-(1-methylpyrazol-4-yl)quinoxaline
Show/Hide
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C24H29N7O4S
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2
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| 1 |
IC50 = 204.17 nM
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| 2 |
IC50 > 10000 nM
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CP0692285
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(4-hydroxypyridin-2-yl)acetamide
Show/Hide
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C27H25N7O4
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2
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| 1 |
IC50 = 218.78 nM
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| 2 |
IC50 > 10000 nM
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CP0704633
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1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-3-ol hydrochloride
Show/Hide
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C27H33ClN6O3
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2
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| 1 |
IC50 = 223.87 nM
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| 2 |
IC50 > 10000 nM
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CP0726411
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
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C27H33ClN6O2
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2
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| 1 |
IC50 = 223.87 nM
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| 2 |
IC50 > 10000 nM
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CP0751775
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2-(4-(7-((3,5-dimethoxyphenyl)(3-(pyrrolidin-1-yl)propyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol hydrochloride
Show/Hide
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C28H35ClN6O3
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2
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| 1 |
IC50 = 229.09 nM
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| 2 |
IC50 > 10000 nM
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CP0575673
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N-(5-cyclopropyl-1,2-oxazol-3-yl)-5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
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C22H20N6O3
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1
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| 1 |
IC50 = 230 nM
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CP0762381
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N-(3,5-dimethoxy-2-methylphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
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C28H35ClN6O2
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2
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| 1 |
IC50 = 239.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0424709
|
4-chloro-3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Show/Hide
|
C16H14ClN3O3
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0388615
|
3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxy-6-(1,3-thiazol-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C23H26N6O3S
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0150291
|
3-(1-(6-(4-(diethylamino)butylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C34H37F3N8O
|
1
|
| 1 |
IC50 = 243 nM
|
|
|
|
CP0181870
|
3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C29H23F3N8O
|
1
|
| 1 |
IC50 = 245 nM
|
|
|
|
CP0451476
|
N-(5-cyclopropyl-1,2-oxazol-3-yl)-5-[6-(methylaminomethyl)pyrimidin-4-yl]oxyindole-1-carboxamide
Show/Hide
|
C21H20N6O3
|
1
|
| 1 |
IC50 = 245 nM
|
|
|
|
CP0737875
|
N1-(2,6-difluoro-3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C25H25F5N6O2
|
2
|
| 1 |
IC50 = 245.47 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0166281
|
3-(1-(6-(4-(dimethylamino)butylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C32H33F3N8O
|
1
|
| 1 |
IC50 = 249 nM
|
|
|
|
CP0166371
|
3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-chlorophenyl)-4-methylbenzamide
Show/Hide
|
C25H20ClN7O
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0447358
|
3-[(6,7-dimethoxyquinazolin-4-yl)amino]-5-fluorophenol
Show/Hide
|
C16H14FN3O3
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0719271
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C29H36N6O3
|
2
|
| 1 |
IC50 = 269.15 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0548326
|
5-[6-(methylaminomethyl)pyrimidin-4-yl]oxy-N-[5-(trifluoromethyl)-1H-pyrazol-3-yl]indole-1-carboxamide
Show/Hide
|
C19H16F3N7O2
|
1
|
| 1 |
IC50 = 273 nM
|
|
|
|
CP0166283
|
N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-3-methylbenzamide
Show/Hide
|
C26H23N7O
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0508837
|
2,4-dichloro-5-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Show/Hide
|
C16H13Cl2N3O3
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0151357
|
N-[3-[[1-[6-(2-methoxyethylamino)pyrimidin-4-yl]benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C29H26F3N7O2
|
1
|
| 1 |
IC50 = 296 nM
|
|
|
|
CP0808360
|
N-(3-(5,6-dihydropyridin-1(2H)-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H33ClN6O2
|
2
|
| 1 |
IC50 = 309.03 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0424861
|
5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methoxyphenol
Show/Hide
|
C17H17N3O4
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0227163
|
N-[4-methyl-3-[[1-[6-(3-morpholin-3-ylpropylamino)pyrimidin-4-yl]benzimidazol-2-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C33H33F3N8O2
|
1
|
| 1 |
IC50 = 318 nM
|
|
|
|
CP0875235
|
N-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)methanesulfonamide
Show/Hide
|
C24H28N6O4S
|
2
|
| 1 |
IC50 = 354.81 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0485534
|
2-(4-(6-(6-(2-(2-chloro-6-methylphenylamino)-1H-benzo[d]imidazol-1-yl)pyrimidin-4-ylamino)-2-methylpyrimidin-4-yl)piperazin-1-yl)ethanol
Show/Hide
|
C29H31ClN10O
|
1
|
| 1 |
IC50 = 356 nM
|
|
|
|
CP0424706
|
5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-fluorophenol
Show/Hide
|
C16H14FN3O3
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0831264
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(piperazin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H32ClN7O2
|
2
|
| 1 |
IC50 = 371.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692287
|
3-(4-(7-((3,5-dimethoxyphenyl)(2-(isopropylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)propanenitrile
Show/Hide
|
C27H31N7O2
|
2
|
| 1 |
IC50 = 380.19 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0132914
|
N-[5-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1H-pyrazol-3-yl]-2,2-dimethylpropanamide
Show/Hide
|
C22H28N6O3
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0692223
|
N1-(3,5-dimethoxy-2-methylphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C26H33ClN6O2
|
2
|
| 1 |
IC50 = 398.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701275
|
N-(2-chloro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H32Cl2N6O2
|
2
|
| 1 |
IC50 = 398.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698926
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-fluoropyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H32ClFN6O2
|
2
|
| 1 |
IC50 = 407.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0719256
|
1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)piperidine-3-carboxamide
Show/Hide
|
C29H35N7O3
|
2
|
| 1 |
IC50 = 416.87 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0531626
|
methyl N-[4-[4-amino-5-(3-amino-4-chlorophenyl)pyrrolo[2,3-d]pyrimidin-7-yl]-1-bicyclo[2.2.2]octanyl]carbamate
Show/Hide
|
C22H25ClN6O2
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0841622
|
(R)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H33ClN6O2
|
2
|
| 1 |
IC50 = 446.68 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0875201
|
7-[N-[3-(dimethylsulfamoylamino)propyl]-3,5-dimethoxy-anilino]-2-(1-methylpyrazol-4-yl)quinoxaline
Show/Hide
|
C25H31N7O4S
|
2
|
| 1 |
IC50 = 446.68 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0166284
|
N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-5-tert-butyl-2-methylpyrazole-3-carboxamide
Show/Hide
|
C27H29N9O
|
1
|
| 1 |
IC50 = 451 nM
|
|
|
|
CP0673344
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(4-methylpiperazin-1-yl)ethyl)quinoxalin-6-amine
Show/Hide
|
C27H33N7O2
|
2
|
| 1 |
IC50 = 457.09 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0719249
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-(methylsulfonyl)pyrrolidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C28H34N6O4S
|
2
|
| 1 |
IC50 = 457.09 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0147354
|
3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-bromophenyl)-4-methylbenzamide
Show/Hide
|
C25H20BrN7O
|
1
|
| 1 |
IC50 = 464 nM
|
|
|
|
CP0664771
|
N-(2,6-difluoro-3,5-dimethoxyphenyl)-N-(3-(4-methoxypyrimidin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H23F2N7O3
|
2
|
| 1 |
IC50 = 467.74 nM
|
|
|
| 2 |
IC50 = 5011.87 nM
|
|
|
|
CP0776282
|
N1-(2,6-dichloro-3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C25H28Cl2N6O2
|
2
|
| 1 |
IC50 = 467.74 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0683288
|
N-(3,5-dimethoxyphenyl)-3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O4S
|
2
|
| 1 |
IC50 = 478.63 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704132
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)propane-2-sulfonamide
Show/Hide
|
C25H30N6O4S
|
2
|
| 1 |
IC50 = 478.63 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704723
|
2-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethylamino)ethanol
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 489.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0749417
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C27H35ClN6O2
|
2
|
| 1 |
IC50 = 501.19 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702437
|
3-fluoro-5-((2-hydroxyethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-methylbenzamide
Show/Hide
|
C22H21FN6O2
|
2
|
| 1 |
IC50 = 512.86 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0166372
|
3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-methoxyphenyl)-4-methylbenzamide
Show/Hide
|
C26H23N7O2
|
1
|
| 1 |
IC50 = 516 nM
|
|
|
|
CP0151356
|
N-[4-methyl-3-[[1-[6-(2-pyridin-2-ylethylamino)pyrimidin-4-yl]benzimidazol-2-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C33H27F3N8O
|
1
|
| 1 |
IC50 = 549 nM
|
|
|
|
CP0708035
|
N-(3,5-dimethoxyphenyl)-N-(3-((2S,5S)-2,5-dimethylpyrrolidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H34N6O2
|
2
|
| 1 |
IC50 = 549.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688443
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-morpholinopropyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H33ClN6O3
|
2
|
| 1 |
IC50 = 575.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0690296
|
N1-(3,5-dimethoxyphenyl)-N3-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 575.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0290298
|
N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-3-chlorobenzamide
Show/Hide
|
C25H20ClN7O
|
1
|
| 1 |
IC50 = 576 nM
|
|
|
|
CP0289193
|
N-[4-methyl-3-[[1-[6-[3-(4-methylpiperazin-1-yl)propylamino]pyrimidin-4-yl]benzimidazol-2-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C34H36F3N9O
|
1
|
| 1 |
IC50 = 582 nM
|
|
|
|
CP0268700
|
N-[3-[[1-[6-(2-hydroxyethylamino)pyrimidin-4-yl]benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C28H24F3N7O2
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0358252
|
N-[3-[[1-[6-(4-aminobutylamino)pyrimidin-4-yl]benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H29F3N8O
|
1
|
| 1 |
IC50 = 599 nM
|
|
|
|
CP0701309
|
2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propylamino)acetamide
Show/Hide
|
C25H29N7O3
|
2
|
| 1 |
IC50 = 602.56 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0294208
|
N-[4-methyl-3-[[1-[6-[2-(4-methylpiperazin-1-yl)ethylamino]pyrimidin-4-yl]benzimidazol-2-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C33H34F3N9O
|
1
|
| 1 |
IC50 = 605 nM
|
|
|
|
CP0289530
|
N-[3-[[1-[6-[(4-aminocyclohexyl)amino]pyrimidin-4-yl]benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C32H31F3N8O
|
1
|
| 1 |
IC50 = 609 nM
|
|
|
|
CP0037988
|
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
Show/Hide
|
C22H24BrFN4O2
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0657945
|
N-(2,6-difluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C23H19F2N5O2
|
2
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702427
|
2-(4-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperazin-1-yl)ethanol
Show/Hide
|
C28H35N7O3
|
2
|
| 1 |
IC50 = 645.65 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0494169
|
methyl N-[4-[4-amino-5-(3-amino-4-chlorophenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]carbamate
Show/Hide
|
C20H23ClN6O2
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0664658
|
N1-(cyclopropylmethyl)-N3-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)benzene-1,3-diamine
Show/Hide
|
C23H24N6
|
2
|
| 1 |
IC50 = 676.08 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686857
|
N1-(3,5-dimethoxyphenyl)-N2-ethyl-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C27H35ClN6O2
|
2
|
| 1 |
IC50 = 691.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0770859
|
N-(3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)propyl)-2,2,2-trifluoroacetamide, 2,2,2-trifluoroacetate salt
Show/Hide
|
C26H24F6N6O5
|
2
|
| 1 |
IC50 = 741.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726558
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(pyrrolidin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H31ClN6O2
|
2
|
| 1 |
IC50 = 758.58 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0494166
|
1-[4-[3-[4-amino-5-(4-chloro-3-hydroxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
Show/Hide
|
C22H25ClN6O2
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0385988
|
3-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,4-difluorophenol
Show/Hide
|
C16H13F2N3O3
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0701297
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C30H40ClN7O2
|
2
|
| 1 |
IC50 = 794.33 nM
|
|
|
| 2 |
IC50 = 3981.07 nM
|
|
|
|
CP0494170
|
methyl N-[4-[4-amino-5-(5-amino-4-chloro-2-fluorophenyl)pyrrolo[2,3-d]pyrimidin-7-yl]-1-bicyclo[2.2.2]octanyl]carbamate
Show/Hide
|
C22H24ClFN6O2
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0692231
|
N-(3,5-dimethoxyphenyl)-3-(1-isopropyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 812.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704178
|
(R)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(2-methylpyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O2
|
2
|
| 1 |
IC50 = 812.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717323
|
N1-(3,5-dimethoxyphenyl)-N2-methyl-N1-(3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C28H35ClN6O3
|
2
|
| 1 |
IC50 = 812.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744813
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)ethanesulfonamide
Show/Hide
|
C24H28N6O4S
|
2
|
| 1 |
IC50 = 812.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664659
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(oxiran-2-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C23H23N5O3
|
2
|
| 1 |
IC50 = 831.76 nM
|
|
|
| 2 |
IC50 = 9549.93 nM
|
|
|
|
CP0698829
|
3-methoxy-N-methyl-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)benzamide
Show/Hide
|
C28H33N7O2
|
2
|
| 1 |
IC50 = 831.76 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701301
|
N1-isopropyl-N2-(7-methoxybenzo[d][1,3]dioxol-5-yl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C25H28N6O3
|
2
|
| 1 |
IC50 = 831.76 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704722
|
N1-(3-(2-fluoroethoxy)-5-methoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C26H32ClFN6O2
|
2
|
| 1 |
IC50 = 831.76 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0404584
|
3-(6,7-dimethoxyquinazolin-4-yl)oxyphenol
Show/Hide
|
C16H14N2O4
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0552983
|
1-[4-[3-[4-amino-5-(3-amino-4-chlorophenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
Show/Hide
|
C22H26ClN7O
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0726488
|
2-((2-chloro-3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C22H22ClN5O3
|
2
|
| 1 |
IC50 = 851.14 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0774606
|
N1-(cyclopropylmethyl)-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C26H30N6O2
|
2
|
| 1 |
IC50 = 851.14 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649786
|
N-(3,5-dimethoxyphenyl)-N-methyl-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C21H21N5O2
|
2
|
| 1 |
IC50 = 870.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707087
|
N-(3,5-dimethoxyphenyl)-N-((5,5-dimethylmorpholin-3-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 870.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0227161
|
N-[3-[[1-[6-[4-(diethylamino)butylamino]pyrimidin-4-yl]benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C34H37F3N8O
|
1
|
| 1 |
IC50 = 885 nM
|
|
|
|
CP0036030
|
3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Show/Hide
|
C16H15N3O3
|
1
|
| 1 |
IC50 = 890 nM
|
|
|
|
CP0704643
|
N-(2-(1,4-diazepan-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine, oxalate salt
Show/Hide
|
C29H35N7O6
|
2
|
| 1 |
IC50 = 891.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649806
|
1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidin-3-ol hydrochloride
Show/Hide
|
C26H31ClN6O3
|
2
|
| 1 |
IC50 = 912.01 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698840
|
N-{3,5-Bis[(2H3)methyloxy]phenyl}-N'-(1-methylethyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl](2H4)ethane-1,2-diamine
Show/Hide
|
C25H30N6O2
|
2
|
| 1 |
IC50 = 912.01 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744802
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N2-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C26H32N6O2
|
2
|
| 1 |
IC50 = 912.01 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0809104
|
(S)-1-(2-((3,5-dimethoxyphenyl)(3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidine-3-carbonitrile
Show/Hide
|
C32H37N7O3
|
2
|
| 1 |
IC50 = 912.01 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0661487
|
3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea monophosphate
Show/Hide
|
C26H34Cl2N7O7P
|
2
|
| 1 |
IC50 = 938 nM
|
|
|
| 2 |
IC50 = 1449 nM
|
|
|
|
CP0289528
|
N-[4-methyl-3-[[1-[6-(2-pyrrolidin-2-ylethylamino)pyrimidin-4-yl]benzimidazol-2-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C32H31F3N8O
|
1
|
| 1 |
IC50 = 941 nM
|
|
|
|
CP0692234
|
(1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidin-4-yl)methanol
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 954.99 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707084
|
(1s,4s)-N1-(3,5-dimethoxyphenyl)-N4-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)cyclohexane-1,4-diamine
Show/Hide
|
C29H36N6O2
|
2
|
| 1 |
IC50 = 954.99 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0720046
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(piperidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O2
|
2
|
| 1 |
IC50 = 954.99 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657887
|
tert-butyl 4-(4-(7-((3,5-dimethoxyphenyl)(2-(isopropylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Show/Hide
|
C34H45N7O4
|
2
|
| 1 |
IC50 = 977.24 nM
|
|
|
| 2 |
IC50 = 3801.89 nM
|
|
|
|
CP0385508
|
2-[4-[4-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl]piperazin-1-yl]acetic acid
Show/Hide
|
C27H28FN7O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0383144
|
2-chloro-3-[(6,7-dimethoxyquinazolin-4-yl)amino]-6-methylphenol
Show/Hide
|
C17H16ClN3O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0688440
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C25H30N6O2
|
2
|
| 1 |
IC50 = 1000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0708034
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-((trimethylsilyl)methyl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C26H35ClN6O2Si
|
2
|
| 1 |
IC50 = 1000 nM
|
|
|
| 2 |
IC50 = 9120.11 nM
|
|
|
|
CP0327707
|
N-(2-chloro-6-methylphenyl)-1-[6-[[5-(2-morpholin-4-ylethyl)pyridin-2-yl]amino]pyrimidin-4-yl]benzimidazol-2-amine
Show/Hide
|
C29H29ClN8O
|
1
|
| 1 |
IC50 = 1012 nM
|
|
|
|
CP0290251
|
3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-m-tolylbenzamide
Show/Hide
|
C26H23N7O
|
1
|
| 1 |
IC50 = 1015 nM
|
|
|
|
CP0704153
|
2-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethylamino)acetamide
Show/Hide
|
C24H27N7O3
|
2
|
| 1 |
IC50 = 1047.13 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0833205
|
(S)-(1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-yl)methanol
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 1047.13 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667764
|
N-(2,6-difluoro-3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H24F2N6O3
|
2
|
| 1 |
IC50 = 1071.52 nM
|
|
|
| 2 |
IC50 = 8128.31 nM
|
|
|
|
CP0702104
|
N-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide hydrochloride
Show/Hide
|
C27H30ClF3N6O4
|
2
|
| 1 |
IC50 = 1071.52 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702105
|
N-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
Show/Hide
|
C27H29F3N6O4
|
2
|
| 1 |
IC50 = 1071.52 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0786849
|
(S)-2-(1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-yl)acetonitrile hydrochloride
Show/Hide
|
C29H34ClN7O2
|
2
|
| 1 |
IC50 = 1071.52 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0683289
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(piperidin-1-yl)propan-2-ol
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 1096.48 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686859
|
N-isopropyl-N'-[3-methoxy-5-(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
Show/Hide
|
C25H30N6O2
|
2
|
| 1 |
IC50 = 1096.48 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0720056
|
(S)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(methylamino)propan-2-ol
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 1096.48 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0166374
|
4-methyl-3-(1-(6-(3-(4-methylpiperazin-1-yl)propylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-m-tolylbenzamide
Show/Hide
|
C34H39N9O
|
1
|
| 1 |
IC50 = 1113 nM
|
|
|
|
CP0672791
|
(R)-2-(1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-yl)acetonitrile hydrochloride
Show/Hide
|
C29H34ClN7O2
|
2
|
| 1 |
IC50 = 1122.02 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0683693
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(2-methylpiperidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 1122.02 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692459
|
N-(3-chloro-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H30Cl2N6O
|
2
|
| 1 |
IC50 = 1122.02 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702259
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(piperidin-4-yl)ethyl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O2
|
2
|
| 1 |
IC50 = 1122.02 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717322
|
1-(3-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-one
Show/Hide
|
C29H34N6O3
|
2
|
| 1 |
IC50 = 1122.02 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0803484
|
N2-(3,5-dimethoxyphenyl)-N1-isopropyl-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C26H32N6O2
|
2
|
| 1 |
IC50 = 1122.02 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672785
|
3-((cyclopropylmethyl)(3-(1-(2-methoxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C27H30N6O3
|
2
|
| 1 |
IC50 = 1148.15 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673342
|
N-(3,5-dimethoxyphenyl)-N-(3-(2-methyl-1H-imidazol-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H29N7O2
|
2
|
| 1 |
IC50 = 1148.15 nM
|
|
|
| 2 |
IC50 = 9549.93 nM
|
|
|
|
CP0701266
|
2-(3-methoxy-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)phenoxy)ethanol
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 1148.15 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704721
|
3-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)oxazolidin-2-one
Show/Hide
|
C26H28N6O4
|
2
|
| 1 |
IC50 = 1148.15 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673340
|
N-(2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H30N6O3
|
2
|
| 1 |
IC50 = 1174.9 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0700914
|
N1-(3,5-dimethoxyphenyl)-2-fluoro-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C23H25FN6O2
|
2
|
| 1 |
IC50 = 1174.9 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0424848
|
3-[(6,7-dimethoxyquinazolin-4-yl)amino]-5-methylphenol
Show/Hide
|
C17H17N3O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0657884
|
N1-(3,5-dimethoxyphenyl)-N2,N2-dimethyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 1202.26 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672830
|
N1-(3,5-dimethoxyphenyl)-N3-(1-fluoro-2-methylpropan-2-yl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C27H33FN6O2
|
2
|
| 1 |
IC50 = 1202.26 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649789
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 1230.27 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717320
|
3-((2-(isopropylamino)ethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C26H31N7O2
|
2
|
| 1 |
IC50 = 1230.27 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0888133
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-((2R,6R)-2,6-dimethyltetrahydro-2H-pyran-4-yl)pyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C34H45ClN6O3
|
2
|
| 1 |
IC50 = 1230.27 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702421
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C27H33ClN6O3
|
2
|
| 1 |
IC50 = 1258.93 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726550
|
N-(3,5-dimethoxyphenyl)-N-(3-((2S,5R)-2,5-dimethylpyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O2
|
2
|
| 1 |
IC50 = 1258.93 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664732
|
N-(3,5-dimethoxyphenyl)-N-(2-(1-isopropylpiperidin-4-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C30H38N6O2
|
2
|
| 1 |
IC50 = 1288.25 nM
|
|
|
| 2 |
IC50 = 7943.28 nM
|
|
|
|
CP0673332
|
N'-(3,5-dimethoxyphenyl)-N-isopropyl-N'-[3-[1-(trideuteriomethyl)pyrazol-4-yl]quinoxalin-6-yl]ethane-1,2-diamine
Show/Hide
|
C25H30N6O2
|
2
|
| 1 |
IC50 = 1288.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688421
|
N-(3,5-dimethoxyphenyl)-N-[3-(1,1-dioxo-1,4-thiazinan-4-yl)propyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O4S
|
2
|
| 1 |
IC50 = 1288.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701289
|
N-(3,5-dimethoxyphenyl)-N-(3-((2S,5S)-2,5-dimethylpyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 1288.25 nM
|
|
|
| 2 |
IC50 = 9549.93 nM
|
|
|
|
CP0704180
|
N1-(2-chloro-5-methoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C24H28Cl2N6O
|
2
|
| 1 |
IC50 = 1288.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0749419
|
N1-(3,5-dimethoxyphenyl)-N3-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine hydrochloride
Show/Hide
|
C26H33ClN6O2
|
2
|
| 1 |
IC50 = 1288.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0786940
|
2-(4-(7-((3,5-dimethoxyphenyl)(3-(pyrrolidin-1-yl)propyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C29H35N7O3
|
2
|
| 1 |
IC50 = 1288.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0458733
|
3-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-fluorophenol
Show/Hide
|
C16H14FN3O3
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0657948
|
N-(3,5-Dimethoxyphenyl)-N'-(1-methylethyl)-N-{3-[1-(tetrahydro-2H-pyran-4-ylmethyl)-1 H-pyrazol-4-yl]quinoxalin-6-yl}ethane-1,2-diamine hydrochloride
Show/Hide
|
C30H39ClN6O3
|
2
|
| 1 |
IC50 = 1318.26 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707083
|
N-(3,5-Dimethoxyphenyl)-N'-(1-methylethyl)-N-[3-(1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine hydrochloride
Show/Hide
|
C24H29ClN6O2
|
2
|
| 1 |
IC50 = 1318.26 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707085
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-((tetrahydrofuran-2-yl)methyl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C27H33ClN6O3
|
2
|
| 1 |
IC50 = 1318.26 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0735246
|
(R)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(methylamino)propan-2-ol
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 1318.26 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0799261
|
N-(3,5-dimethoxyphenyl)-N-(furo[3,2-b]pyridin-2-ylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H24N6O3
|
2
|
| 1 |
IC50 = 1318.26 nM
|
|
|
| 2 |
IC50 = 4365.16 nM
|
|
|
|
CP0166280
|
3-(1-(6-(4-(diethylamino)butylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-m-tolylbenzamide
Show/Hide
|
C34H40N8O
|
1
|
| 1 |
IC50 = 1364 nM
|
|
|
|
CP0166278
|
N-[3-[[1-[6-[4-(dimethylamino)butylamino]pyrimidin-4-yl]benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C32H33F3N8O
|
1
|
| 1 |
IC50 = 1365 nM
|
|
|
|
CP0690264
|
1,1,2,2-tetradeuterio-2-[N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-3,5-bis(trideuteriomethoxy)anilino]ethanol
Show/Hide
|
C22H23N5O3
|
2
|
| 1 |
IC50 = 1380.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707205
|
N1-cyclopentyl-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C27H32N6O2
|
2
|
| 1 |
IC50 = 1380.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0756692
|
3-(4-(3-(4-(7-((3,5-dimethoxyphenyl)(2-(isopropylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)propyl)piperazin-1-yl)propan-1-ol hydrochloride
Show/Hide
|
C34H49ClN8O3
|
2
|
| 1 |
IC50 = 1380.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0837822
|
(S)-1-((S)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2-hydroxypropyl)pyrrolidine-3-carbonitrile hydrochloride
Show/Hide
|
C28H32ClN7O3
|
2
|
| 1 |
IC50 = 1380.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0558005
|
3-[(6,7-dimethoxyquinazolin-4-yl)amino]-4-methylphenol
Show/Hide
|
C17H17N3O3
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0664763
|
4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)nicotinonitrile
Show/Hide
|
C29H23N7O2
|
2
|
| 1 |
IC50 = 1445.44 nM
|
|
|
| 2 |
IC50 = 1548.82 nM
|
|
|
|
CP0717318
|
2-((3,5-dimethoxy-2-methylphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 1445.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0289196
|
N-[3-[[1-[6-(3-aminopropylamino)pyrimidin-4-yl]benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C29H27F3N8O
|
1
|
| 1 |
IC50 = 1472 nM
|
|
|
|
CP0664746
|
3-((2-(isopropylamino)ethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenol
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 1479.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692290
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(2-methylpiperidin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O2
|
2
|
| 1 |
IC50 = 1479.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704645
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
Show/Hide
|
C26H27F3N6O4
|
2
|
| 1 |
IC50 = 1479.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0166379
|
3-(1-(6-(4-(dimethylamino)butylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-m-tolylbenzamide
Show/Hide
|
C32H36N8O
|
1
|
| 1 |
IC50 = 1497 nM
|
|
|
|
CP0385512
|
3-(6,7-dimethoxyquinazolin-4-yl)sulfanylphenol
Show/Hide
|
C16H14N2O3S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0657944
|
1-(4-(4-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperazin-1-yl)piperidin-1-yl)ethanone
Show/Hide
|
C33H42N8O3
|
2
|
| 1 |
IC50 = 1513.56 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664775
|
N-(3,5-dimethoxyphenyl)-N-(3-(2,2-dimethylpyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 1513.56 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673335
|
N-(3,5-Dimethoxyphenyl)-N-[3-(1-ethyl-1H-pyrazol-4-yl)quinoxalin-6-yl]-N'-(1-methylethyl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C26H33ClN6O2
|
2
|
| 1 |
IC50 = 1513.56 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692262
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(morpholin-3-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C25H28N6O3
|
2
|
| 1 |
IC50 = 1513.56 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0215403
|
1-[4-(3-amino-1H-pyrazol-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea
Show/Hide
|
C17H20N6O2
|
1
|
| 1 |
IC50 = 1520 nM
|
|
|
|
CP0657860
|
N-(2-(3-aminopyrrolidin-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H32ClN7O2
|
2
|
| 1 |
IC50 = 1548.82 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686854
|
3-{(Cyclopropylmethyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-5-fluoro-N-methylbenzamide
Show/Hide
|
C24H23FN6O
|
2
|
| 1 |
IC50 = 1548.82 nM
|
|
|
| 2 |
IC50 >= 10000 nM
|
|
|
|
CP0692219
|
N-isopropyl-N'-[3-methoxy-5-(trideuteriomethoxy)phenyl]-N'-[3-(1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine hydrochloride
Show/Hide
|
C24H29ClN6O2
|
2
|
| 1 |
IC50 = 1548.82 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664758
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1,5-dimethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-isopropylethane-1,2-diamine
Show/Hide
|
C26H32N6O2
|
2
|
| 1 |
IC50 = 1584.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698820
|
N-(2-(3-aminopiperidin-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H33N7O2
|
2
|
| 1 |
IC50 = 1584.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0735320
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(methylamino)propan-2-ol
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 1584.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0770858
|
(S)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(2-methylpyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O2
|
2
|
| 1 |
IC50 = 1584.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664757
|
3-[N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-3,5-bis(trideuteriomethoxy)anilino]propan-1-ol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 1621.81 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672787
|
N1-(3-fluoro-5-methoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H27FN6O
|
2
|
| 1 |
IC50 = 1621.81 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672906
|
N-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)-2,2,2-trifluoroacetamide
Show/Hide
|
C25H25F3N6O3
|
2
|
| 1 |
IC50 = 1621.81 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692281
|
N-(3,5-dimethoxyphenyl)-N-ethyl-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C22H23N5O2
|
2
|
| 1 |
IC50 = 1621.81 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672779
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(methylamino)propan-2-ol hydrochloride
Show/Hide
|
C24H29ClN6O3
|
2
|
| 1 |
IC50 = 1659.59 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657879
|
(R)-(1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-yl)methanol
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 1698.24 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698928
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(piperidin-4-ylmethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H31ClN6O2
|
2
|
| 1 |
IC50 = 1698.24 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704174
|
4-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethylamino)piperidine-1-sulfonamide
Show/Hide
|
C27H34N8O4S
|
2
|
| 1 |
IC50 = 1698.24 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0772358
|
4-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)butanenitrile
Show/Hide
|
C24H24N6O2
|
2
|
| 1 |
IC50 = 1698.24 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0150281
|
N-[4-methyl-3-[[1-[6-[(1-methylpiperidin-4-yl)amino]pyrimidin-4-yl]benzimidazol-2-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C32H31F3N8O
|
1
|
| 1 |
IC50 = 1712 nM
|
|
|
|
CP0561846
|
5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-(5-methyl-1,2-oxazol-3-yl)indole-1-carboxamide
Show/Hide
|
C19H16N6O3
|
1
|
| 1 |
IC50 = 1720 nM
|
|
|
|
CP0298947
|
N-[3-[[1-[6-[2-(diethylamino)ethylamino]pyrimidin-4-yl]benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C32H33F3N8O
|
1
|
| 1 |
IC50 = 1726 nM
|
|
|
|
CP0688437
|
N1-(3,5-dimethoxyphenyl)-N2,N2-diethyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C26H32N6O2
|
2
|
| 1 |
IC50 = 1737.8 nM
|
|
|
| 2 |
IC50 = 2454.71 nM
|
|
|
|
CP0690269
|
N-(3-(6-amino-2-methylpyrimidin-4-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H26N8O2
|
2
|
| 1 |
IC50 = 1737.8 nM
|
|
|
| 2 |
IC50 = 2041.74 nM
|
|
|
|
CP0692289
|
N-(3-(3-aminopyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H33N7O2
|
2
|
| 1 |
IC50 = 1737.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0166285
|
N-[3-[[1-[6-(2-aminoethylamino)pyrimidin-4-yl]benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C28H25F3N8O
|
1
|
| 1 |
IC50 = 1748 nM
|
|
|
|
CP0673353
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C29H37N7O2
|
2
|
| 1 |
IC50 = 1778.28 nM
|
|
|
| 2 |
IC50 = 2454.71 nM
|
|
|
|
CP0688422
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 1778.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0749420
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(5-ethyl-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-isopropylethane-1,2-diamine hydrochloride
Show/Hide
|
C27H35ClN6O2
|
2
|
| 1 |
IC50 = 1778.28 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0803483
|
N-[2-(4-Acetylpiperazin-1-yl)ethyl]-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H33N7O3
|
2
|
| 1 |
IC50 = 1778.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688429
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-morpholinoethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H31ClN6O3
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698821
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)butane-1,4-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701286
|
2-(1-(2-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidin-4-yl)propan-2-ol
Show/Hide
|
C32H42N6O3
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707215
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-((2S,6R)-2,6-dimethylmorpholino)pyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C33H44ClN7O3
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744803
|
1,1,2,2,3,3-hexadeuterio-3-[N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-3,5-bis(trideuteriomethoxy)anilino]propan-1-ol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0746821
|
1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidine-3-carboxamide
Show/Hide
|
C28H33N7O3
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692233
|
(S)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H33ClN6O2
|
2
|
| 1 |
IC50 = 1862.09 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692267
|
2-((2,6-dichloro-3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C22H21Cl2N5O3
|
2
|
| 1 |
IC50 = 1862.09 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0751772
|
N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)-N-(2-(pyrrolidin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C25H29ClN6O2
|
2
|
| 1 |
IC50 = 1862.09 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0385522
|
4-chloro-3-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-fluorophenol
Show/Hide
|
C16H13ClFN3O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0649802
|
N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C26H30N6O2
|
2
|
| 1 |
IC50 = 1905.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673346
|
N-(3,5-dimethoxyphenyl)-N-(3-(2,5-dimethyl-1H-imidazol-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H32ClN7O2
|
2
|
| 1 |
IC50 = 1905.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0200224
|
N-(5-methylpyridin-3-yl)-5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
Show/Hide
|
C22H20N6O2
|
1
|
| 1 |
IC50 = 1922 nM
|
|
|
|
CP0664760
|
2-((3,5-dimethoxyphenyl)(3-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 1949.84 nM
|
|
|
| 2 |
IC50 = 9549.93 nM
|
|
|
|
CP0672767
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3-fluoro-5-methoxyphenyl)-N2-isopropylethane-1,2-diamine hydrochloride
Show/Hide
|
C23H26ClFN6O
|
2
|
| 1 |
IC50 = 1949.84 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0683290
|
5-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)-1,3,4-oxadiazol-2-amine
Show/Hide
|
C23H22N8O3
|
2
|
| 1 |
IC50 = 1949.84 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692294
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(4-(trifluoromethyl)piperidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C29H33F3N6O2
|
2
|
| 1 |
IC50 = 1949.84 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0708038
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrimidin-2-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C27H27N7O2
|
2
|
| 1 |
IC50 = 1949.84 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667763
|
4-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)but-2-yn-1-ol
Show/Hide
|
C24H23N5O3
|
2
|
| 1 |
IC50 = 2041.74 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673333
|
N-(3,5-dimethoxyphenyl)-N-(2-(3-(dimethylamino)pyrrolidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H35N7O2
|
2
|
| 1 |
IC50 = 2041.74 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673348
|
N-(2-(5,6-dihydropyridin-1(2H)-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H31ClN6O2
|
2
|
| 1 |
IC50 = 2041.74 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707212
|
N-(3,5-dimethoxyphenyl)-N-(3-(4-methoxypiperidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O3
|
2
|
| 1 |
IC50 = 2041.74 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672789
|
2-(1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidin-4-yl)ethanol
Show/Hide
|
C29H36N6O3
|
2
|
| 1 |
IC50 = 2089.3 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702107
|
N1-(2,2-difluoroethyl)-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H26F2N6O2
|
2
|
| 1 |
IC50 = 2089.3 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702439
|
N-(3-(4-aminopyridin-2-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O2
|
2
|
| 1 |
IC50 = 2089.3 nM
|
|
|
| 2 |
IC50 = 2290.87 nM
|
|
|
|
CP0704646
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-propyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C24H29ClN6O2
|
2
|
| 1 |
IC50 = 2089.3 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0756690
|
4-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-2-methylbutan-2-ol
Show/Hide
|
C25H29N5O3
|
2
|
| 1 |
IC50 = 2089.3 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0150285
|
4-methyl-3-(1-(6-(2-(4-methylpiperazin-1-yl)ethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-m-tolylbenzamide
Show/Hide
|
C33H37N9O
|
1
|
| 1 |
IC50 = 2094 nM
|
|
|
|
CP0019908
|
BDBM50242742
Show/Hide
|
C30H40ClN7O3S
|
1
|
| 1 |
IC50 = 2123 nM
|
|
|
|
CP0701274
|
2-(3,5-dimethoxy-N-[7-[1-(trideuteriomethyl)pyrazol-4-yl]quinoxalin-2-yl]anilino)ethanol
Show/Hide
|
C22H23N5O3
|
2
|
| 1 |
IC50 = 2137.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717319
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(2-chloro-5-methoxyphenyl)-N2-isopropylethane-1,2-diamine hydrochloride
Show/Hide
|
C23H26Cl2N6O
|
2
|
| 1 |
IC50 = 2137.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692292
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(2,5-dimethoxyphenyl)-N2-isopropylethane-1,2-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 2187.76 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744805
|
N-(2,6-dichloro-3,5-dimethoxyphenyl)-N-(3-(4-methoxypyrimidin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H23Cl2N7O3
|
2
|
| 1 |
IC50 = 2187.76 nM
|
|
|
| 2 |
IC50 = 9120.11 nM
|
|
|
|
CP0657064
|
3-(3,5-dimethoxy-N-[3-[1-(2-methylsulfonylethyl)pyrazol-4-yl]quinoxalin-6-yl]anilino)propan-1-ol
Show/Hide
|
C25H29N5O5S
|
2
|
| 1 |
IC50 = 2238.72 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657877
|
2-[3-methoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-5-(trideuteriomethoxy)anilino]ethanol
Show/Hide
|
C22H23N5O3
|
2
|
| 1 |
IC50 = 2238.72 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686570
|
(4-(7-((3,5-dimethoxyphenyl)(2-(isopropylamino)ethyl)amino)quinoxalin-2-yl)-1-methyl-1H-pyrazol-5-yl)methanol
Show/Hide
|
C26H32N6O3
|
2
|
| 1 |
IC50 = 2238.72 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0688423
|
(1R,4R)-N1-(3,5-dimethoxyphenyl)-N4-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)cyclohexane-1,4-diamine
Show/Hide
|
C29H36N6O2
|
2
|
| 1 |
IC50 = 2238.72 nM
|
|
|
| 2 |
IC50 = 5011.87 nM
|
|
|
|
CP0704128
|
N-(3-(2-aminopyrimidin-4-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H24N8O2
|
2
|
| 1 |
IC50 = 2238.72 nM
|
|
|
| 2 |
IC50 = 2454.71 nM
|
|
|
|
CP0707214
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)acetamide
Show/Hide
|
C24H26N6O3
|
2
|
| 1 |
IC50 = 2238.72 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0831270
|
3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C25H26N6O2
|
2
|
| 1 |
IC50 = 2238.72 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657886
|
N-(2-((1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H32ClN7O2
|
2
|
| 1 |
IC50 = 2290.87 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664747
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(2,2,2-trifluoroethyl)propanamide
Show/Hide
|
C25H25F3N6O3
|
2
|
| 1 |
IC50 = 2290.87 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664753
|
3-((2-hydroxyethyl)(3-(1-(2-methoxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C25H28N6O4
|
2
|
| 1 |
IC50 = 2290.87 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0786939
|
3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)propan-1-ol
Show/Hide
|
C22H23N5O3
|
2
|
| 1 |
IC50 = 2290.87 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0700932
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)-1-methylpiperidine-3-carboxamide
Show/Hide
|
C29H35N7O3
|
2
|
| 1 |
IC50 = 2344.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726309
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-ethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-methylethane-1,2-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 2344.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0746843
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(piperidin-1-yl)ethyl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O2
|
2
|
| 1 |
IC50 = 2344.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692283
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(methylsulfonyl)ethyl)quinoxalin-6-amine
Show/Hide
|
C23H25N5O4S
|
2
|
| 1 |
IC50 = 2398.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701302
|
2-(4-(3-(4-(7-((3,5-dimethoxyphenyl)(2-(isopropylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)propyl)piperazin-1-yl)ethanol hydrochloride
Show/Hide
|
C33H47ClN8O3
|
2
|
| 1 |
IC50 = 2398.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702434
|
(3S)-1-(2-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}ethyl)pyrrolidine-3-carbonitrile
Show/Hide
|
C27H29N7O2
|
2
|
| 1 |
IC50 = 2398.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0756689
|
N-((5-chlorothiophen-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(piperazin-1-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C30H33Cl2N7O2S
|
2
|
| 1 |
IC50 = 2398.83 nM
|
|
|
| 2 |
IC50 = 5128.61 nM
|
|
|
|
CP0775910
|
3-{4-[3-(4-{7-[(Cyclopropylmethyl)(3,5-dimethoxyphenyl)amino]quinoxalin-2-yl}-1H-pyrazol-1-yl)propyl]piperazin-1-yl}propan-1-ol hydrochloride
Show/Hide
|
C33H44ClN7O3
|
2
|
| 1 |
IC50 = 2398.83 nM
|
|
|
| 2 |
IC50 = 5011.87 nM
|
|
|
|
CP0850944
|
(S)-1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidine-3-carbonitrile hydrochloride
Show/Hide
|
C28H32ClN7O2
|
2
|
| 1 |
IC50 = 2398.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0283468
|
1-[4-(5-amino-1,2-oxazol-3-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea
Show/Hide
|
C17H19N5O3
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0698845
|
N-(3-(2-amino-6-chloropyrimidin-4-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H23ClN8O2
|
2
|
| 1 |
IC50 = 2511.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726454
|
N1-(3,5-dimethoxyphenyl)-N2-(2-fluoroethyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H27FN6O2
|
2
|
| 1 |
IC50 = 2511.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726561
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C22H23N5O3
|
2
|
| 1 |
IC50 = 2511.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0775911
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-methylethane-1,2-diamine hydrochloride
Show/Hide
|
C25H31ClN6O2
|
2
|
| 1 |
IC50 = 2511.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649794
|
2-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C23H25N5O4
|
2
|
| 1 |
IC50 = 2570.4 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657828
|
N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 2570.4 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657881
|
3-((2-hydroxyethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenol
Show/Hide
|
C21H21N5O3
|
2
|
| 1 |
IC50 = 2570.4 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657882
|
N1-isopropyl-N2-(3-methoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C24H29ClN6O
|
2
|
| 1 |
IC50 = 2570.4 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673338
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-ethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 2570.4 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692301
|
N1-(3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)-N2-isopropylethane-1,2-diamine, 2,2,2-trifluoroacetate salt
Show/Hide
|
C29H36F3N7O4
|
2
|
| 1 |
IC50 = 2570.4 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707114
|
N-(3,5-Dimethoxyphenyl)-N-(1H-imidazol-2-ylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H23N7O2
|
2
|
| 1 |
IC50 = 2570.4 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0848580
|
1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)piperidine-3-carbonitrile
Show/Hide
|
C29H33N7O2
|
2
|
| 1 |
IC50 = 2570.4 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649801
|
3-((3,5-dimethoxyphenyl)(3-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C24H27N5O4
|
2
|
| 1 |
IC50 = 2630.27 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657835
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-(piperidin-1-yl)pyrrolidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C32H41N7O2
|
2
|
| 1 |
IC50 = 2630.27 nM
|
|
|
| 2 |
IC50 = 7413.1 nM
|
|
|
|
CP0657941
|
(R)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(isopropylamino)propan-2-ol hydrochloride
Show/Hide
|
C26H33ClN6O3
|
2
|
| 1 |
IC50 = 2630.27 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698816
|
3-((3,5-dimethoxyphenyl)(3-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C27H31N5O4
|
2
|
| 1 |
IC50 = 2630.27 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744811
|
2-((3,5-dimethoxyphenyl)(3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C24H27N5O5S
|
2
|
| 1 |
IC50 = 2630.27 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707115
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine hydrochloride
Show/Hide
|
C26H33ClN6O2
|
2
|
| 1 |
IC50 = 2691.53 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0756693
|
N-(2-(1H-pyrazol-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C25H26ClN7O2
|
2
|
| 1 |
IC50 = 2691.53 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0772374
|
(S)-(1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidin-2-yl)methanol
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 2691.53 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672905
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-(methylamino)pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H36ClN7O2
|
2
|
| 1 |
IC50 = 2754.23 nM
|
|
|
| 2 |
IC50 = 8317.64 nM
|
|
|
|
CP0688394
|
2-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C24H26N6O4
|
2
|
| 1 |
IC50 = 2754.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698828
|
N-(3,5-dimethoxyphenyl)-N-(3-((2S,5R)-2,5-dimethylpyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 2754.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702251
|
N1-(4-aminobenzyl)-N2-(3,5-dimethoxyphenyl)-N1-isopropyl-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C32H37N7O2
|
2
|
| 1 |
IC50 = 2754.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702406
|
N1-(2,2-difluoroethyl)-N3-(3,5-dimethoxyphenyl)-N3-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C25H28F2N6O2
|
2
|
| 1 |
IC50 = 2754.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704130
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(piperazin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C27H33N7O2
|
2
|
| 1 |
IC50 = 2754.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0719608
|
2-(4-(7-((3,5-dimethoxyphenyl)(3-hydroxypropyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C25H28N6O4
|
2
|
| 1 |
IC50 = 2754.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0809103
|
N1-(3,5-dimethoxyphenyl)-N3-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C26H32N6O2
|
2
|
| 1 |
IC50 = 2754.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672777
|
N-allyl-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H23N5O2
|
2
|
| 1 |
IC50 = 2818.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701290
|
N1-(3-fluoro-5-methoxyphenyl)-N3-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C25H29FN6O
|
2
|
| 1 |
IC50 = 2818.38 nM
|
|
|
| 2 |
IC50 = 8128.31 nM
|
|
|
|
CP0698819
|
N-(3,5-dimethoxyphenyl)-N-(2-(2,6-dimethylpiperidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O2
|
2
|
| 1 |
IC50 = 2884.03 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701265
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((2-methylthiazol-4-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C25H24N6O2S
|
2
|
| 1 |
IC50 = 2884.03 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704642
|
(S)-1-((R)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2-hydroxypropyl)pyrrolidine-3-carbonitrile hydrochloride
Show/Hide
|
C28H32ClN7O3
|
2
|
| 1 |
IC50 = 2884.03 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707162
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1,3,5-trimethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C27H35ClN6O2
|
2
|
| 1 |
IC50 = 2884.03 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0167790
|
4-(4-Bromo-2-fluoroanilino)-6,7-dimethoxyquinazoline
Show/Hide
|
C16H13BrFN3O2
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0657885
|
N1-(2,2-difluoropropyl)-N3-(3,5-dimethoxyphenyl)-N3-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C26H30F2N6O2
|
2
|
| 1 |
IC50 = 2951.21 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664784
|
3-((cyclopropylmethyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-fluoro-N-methylbenzamide
Show/Hide
|
C26H27FN6O
|
2
|
| 1 |
IC50 = 2951.21 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692232
|
N1-(3-fluoro-5-methoxyphenyl)-N2-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C22H23FN6O
|
2
|
| 1 |
IC50 = 2951.21 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744814
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)propane-1,3-diamine
Show/Hide
|
C22H24N6O2
|
2
|
| 1 |
IC50 = 2951.21 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0749416
|
2-((3-(2-fluoroethoxy)-5-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C23H24FN5O3
|
2
|
| 1 |
IC50 = 2951.21 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657940
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(oxetan-3-yl)quinoxalin-6-amine
Show/Hide
|
C23H23N5O3
|
2
|
| 1 |
IC50 = 3019.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672782
|
(2S)-1-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-3-[(1-methylethyl)amino]propan-2-ol hydrochloride
Show/Hide
|
C26H33ClN6O3
|
2
|
| 1 |
IC50 = 3019.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0690290
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((3-methylisoxazol-5-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C25H24N6O3
|
2
|
| 1 |
IC50 = 3019.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701269
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(thiophen-2-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C25H23N5O2S
|
2
|
| 1 |
IC50 = 3019.95 nM
|
|
|
| 2 |
IC50 > 3019.95 nM
|
|
|
|
CP0707096
|
(E/Z)-N-(3,5-dimethoxyphenyl)-N-(3-(4-methoxypyrimidin-2-yl)allyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H27N7O3
|
2
|
| 1 |
IC50 = 3019.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0719349
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(pyridin-3-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C26H24N6O2
|
2
|
| 1 |
IC50 = 3019.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701303
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrazin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C27H23N7O2
|
2
|
| 1 |
IC50 = 3090.3 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0702103
|
N-(3-fluoro-5-methoxyphenyl)-3-(1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C25H28ClFN6O
|
2
|
| 1 |
IC50 = 3090.3 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0708037
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyridin-4-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C28H28N6O2
|
2
|
| 1 |
IC50 = 3090.3 nM
|
|
|
| 2 |
IC50 >= 10000 nM
|
|
|
|
CP0867047
|
1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidin-4-ol
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 3090.3 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698815
|
N-(3-(3-chloropyrazin-2-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H22ClN7O2
|
2
|
| 1 |
IC50 = 3162.28 nM
|
|
|
| 2 |
IC50 = 3311.31 nM
|
|
|
|
CP0702261
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-morpholinopropan-2-ol
Show/Hide
|
C27H32N6O4
|
2
|
| 1 |
IC50 = 3162.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744810
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propane-1,2-diol
Show/Hide
|
C23H25N5O4
|
2
|
| 1 |
IC50 = 3162.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0773267
|
3-[(2-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}ethyl)amino]propanenitrile
Show/Hide
|
C25H27N7O2
|
2
|
| 1 |
IC50 = 3162.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667756
|
(S)-1-[(3,5-Dimethoxyphenyl){3-[1-(1-methylethyl)-1H-pyrazol-4-yl]quinoxalin-6-yl}amino]-3-methoxypropan-2-ol hydrochloride
Show/Hide
|
C26H32ClN5O4
|
2
|
| 1 |
IC50 = 3235.94 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686861
|
(2R*)-3-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C23H22F3N5O3
|
2
|
| 1 |
IC50 = 3235.94 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0757779
|
(R)-1-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-ol hydrochloride
Show/Hide
|
C26H32ClN5O4
|
2
|
| 1 |
IC50 = 3235.94 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0757781
|
2-(4-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)-1H-1,2,3-triazol-1-yl)ethanol
Show/Hide
|
C25H26N8O3
|
2
|
| 1 |
IC50 = 3235.94 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0775902
|
1-amino-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-2-ol
Show/Hide
|
C23H26N6O3
|
2
|
| 1 |
IC50 = 3235.94 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0816363
|
3-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C25H26F3N5O3
|
2
|
| 1 |
IC50 = 3235.94 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0064283
|
Balversa
Show/Hide
|
C25H30N6O2
|
2
|
| 1 |
IC50 = 3311.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0719348
|
(2S)-1-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-3-[(2,2,2-trifluoroethyl)amino]propan-2-ol
Show/Hide
|
C25H27F3N6O3
|
2
|
| 1 |
IC50 = 3311.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688441
|
1-(3-((3-fluoro-5-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidine-3-carbonitrile
Show/Hide
|
C27H28FN7O
|
2
|
| 1 |
IC50 = 3388.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701307
|
(Z)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrimidin-2-yl)allyl)quinoxalin-6-amine
Show/Hide
|
C27H25N7O2
|
2
|
| 1 |
IC50 = 3388.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707210
|
N-(3,5-Dimethoxyphenyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]propane-1,3-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 3388.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0708031
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(isopropylamino)propan-2-ol
Show/Hide
|
C26H32N6O3
|
2
|
| 1 |
IC50 = 3388.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0751769
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propanenitrile
Show/Hide
|
C23H22N6O2
|
2
|
| 1 |
IC50 = 3388.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667769
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 3467.37 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692293
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)cyclopropanecarboxamide
Show/Hide
|
C26H28N6O3
|
2
|
| 1 |
IC50 = 3467.37 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692296
|
3-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C25H29N5O3
|
2
|
| 1 |
IC50 = 3467.37 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0775912
|
N-(3,5-dimethoxyphenyl)-N-((2-methylthiazol-4-yl)methyl)-3-(1-(2-(piperazin-1-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C30H34N8O2S
|
2
|
| 1 |
IC50 = 3467.37 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672901
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-2-ol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 3548.13 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686855
|
N-(3,5-dimethoxyphenyl)-N-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H37N7O2
|
2
|
| 1 |
IC50 = 3548.13 nM
|
|
|
| 2 |
IC50 = 6456.54 nM
|
|
|
|
CP0688468
|
3-((3,5-dimethoxyphenyl)(3-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propanenitrile
Show/Hide
|
C24H24N6O3
|
2
|
| 1 |
IC50 = 3548.13 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0719341
|
2-(1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidin-4-yl)propan-2-ol
Show/Hide
|
C30H38N6O3
|
2
|
| 1 |
IC50 = 3715.35 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0864356
|
3-((3-(2-hydroxyethoxy)-5-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C24H27N5O4
|
2
|
| 1 |
IC50 = 3801.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686566
|
N1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)-N1-isopropylpropane-1,3-diamine hydrochloride
Show/Hide
|
C28H38ClN7O2
|
2
|
| 1 |
IC50 = 3890.45 nM
|
|
|
| 2 |
IC50 = 6309.57 nM
|
|
|
|
CP0744806
|
N-(3,5-dimethoxyphenyl)-N-(3-(6-methoxypyrimidin-4-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O3
|
2
|
| 1 |
IC50 = 3890.45 nM
|
|
|
| 2 |
IC50 = 4168.69 nM
|
|
|
|
CP0751771
|
2-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)ethanol
Show/Hide
|
C21H21N5O3
|
2
|
| 1 |
IC50 = 3890.45 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0888134
|
N-(3-(3,3-difluoroazetidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H28F2N6O2
|
2
|
| 1 |
IC50 = 3890.45 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0675654
|
1-(3-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}propyl)pyrrolidin-2-one
Show/Hide
|
C27H30N6O3
|
2
|
| 1 |
IC50 = 3981.07 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692275
|
2-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1-methyl-1H-pyrazol-5-yl)ethanol
Show/Hide
|
C24H27N5O4
|
2
|
| 1 |
IC50 = 3981.07 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0756736
|
2-(4-{7-[(3,5-Dimethoxyphenyl){2-[(1-methylethyl)amino]ethyl}amino]quinoxalin-2-yl}-1H-pyrazol-1-yl)-N-methylacetamide hydrochloride
Show/Hide
|
C27H34ClN7O3
|
2
|
| 1 |
IC50 = 4073.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0388864
|
4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrile
Show/Hide
|
C20H15N5
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0667758
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-methoxy-N-methylpropanamide
Show/Hide
|
C25H28N6O4
|
2
|
| 1 |
IC50 = 4168.69 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692295
|
(R)-(1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidin-2-yl)methanol
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 4168.69 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702432
|
N-(3,5-dimethoxyphenyl)-N-(2-(4-(dimethylamino)piperidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H37N7O2
|
2
|
| 1 |
IC50 = 4168.69 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0864355
|
3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(cyclopropylmethyl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C24H24N6O2
|
2
|
| 1 |
IC50 = 4168.69 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657880
|
1-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-ol
Show/Hide
|
C26H31N5O4
|
2
|
| 1 |
IC50 = 4265.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664720
|
N-(3-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((3-methylisoxazol-5-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C24H22N6O2
|
2
|
| 1 |
IC50 = 4265.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664761
|
2-((3,5-dimethoxyphenyl)(3-(5-ethyl-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C24H27N5O3
|
2
|
| 1 |
IC50 = 4265.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672790
|
cyclopropyl(4-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperazin-1-yl)methanone
Show/Hide
|
C30H35N7O3
|
2
|
| 1 |
IC50 = 4265.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673349
|
1-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-ol hydrochloride
Show/Hide
|
C26H32ClN5O4
|
2
|
| 1 |
IC50 = 4265.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0683435
|
N-(3,5-dimethoxyphenyl)-N-(furan-2-ylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C25H23N5O3
|
2
|
| 1 |
IC50 = 4265.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0700890
|
N-[3,5-bis(trideuteriomethoxy)phenyl]-1,1,2,2,3,3-hexadeuterio-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N'-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C25H27F3N6O2
|
2
|
| 1 |
IC50 = 4265.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0762382
|
(R)-3-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C25H26F3N5O3
|
2
|
| 1 |
IC50 = 4265.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0805802
|
(Z)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-one oxime
Show/Hide
|
C24H26N6O4
|
2
|
| 1 |
IC50 = 4265.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0112798
|
N-(5-tert-butyl-1,2-oxazol-3-yl)-5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)indazole-1-carboxamide
Show/Hide
|
C21H21N7O3
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0683691
|
N-(3,5-dimethoxyphenyl)-N-(2-methoxyethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 4466.84 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692255
|
(3-methoxy-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)phenyl)methanol
Show/Hide
|
C27H32N6O2
|
2
|
| 1 |
IC50 = 4466.84 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0775913
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((1-methylpiperidin-4-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O2
|
2
|
| 1 |
IC50 = 4466.84 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657876
|
2-((2-chloro-5-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C21H20ClN5O2
|
2
|
| 1 |
IC50 = 4570.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672831
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(thiazol-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C26H22N6O2S
|
2
|
| 1 |
IC50 = 4570.88 nM
|
|
|
| 2 |
IC50 = 7413.1 nM
|
|
|
|
CP0746822
|
4-(2-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}ethyl)piperazin-2-one
Show/Hide
|
C26H29N7O3
|
2
|
| 1 |
IC50 = 4570.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0776289
|
N1-(3,5-dimethoxyphenyl)-N2-ethyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 4570.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0850943
|
2-(4-(7-((3-fluoro-5-methoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C22H22FN5O3
|
2
|
| 1 |
IC50 = 4570.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673351
|
N'-[3,5-bis(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C25H27F3N6O2
|
2
|
| 1 |
IC50 = 4677.35 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688444
|
(Z)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methylbutan-2-one oxime
Show/Hide
|
C25H28N6O3
|
2
|
| 1 |
IC50 = 4677.35 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0690539
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(piperidin-4-yl)prop-2-ynyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H31ClN6O2
|
2
|
| 1 |
IC50 = 4677.35 nM
|
|
|
| 2 |
IC50 = 7943.28 nM
|
|
|
|
CP0708030
|
2-((3-ethoxy-5-fluorophenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C22H22FN5O2
|
2
|
| 1 |
IC50 = 4677.35 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0404580
|
3-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,6-difluorophenol
Show/Hide
|
C16H13F2N3O3
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0829305
|
2-((3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)ethanol hydrochloride
Show/Hide
|
C24H29ClN6O3
|
2
|
| 1 |
IC50 = 4786.3 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0848579
|
2-(4-(7-((3-aminopropyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 4786.3 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672827
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C26H30ClF3N6O2
|
2
|
| 1 |
IC50 = 4897.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698837
|
(E)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-2-one oxime
Show/Hide
|
C23H24N6O3
|
2
|
| 1 |
IC50 = 4897.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698927
|
N-((2H-1,2,3-triazol-4-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H22N8O2
|
2
|
| 1 |
IC50 = 4897.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0708033
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((3-methyloxetan-3-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C25H27N5O3
|
2
|
| 1 |
IC50 = 4897.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0720054
|
N-(3,5-dimethoxyphenyl)-N-((3-methoxypiperidin-3-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H33ClN6O3
|
2
|
| 1 |
IC50 = 4897.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744816
|
((1R,2R)-2-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)cyclopropyl)methanol
Show/Hide
|
C25H27N5O3
|
2
|
| 1 |
IC50 = 4897.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0749421
|
N-(2,6-dichloro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C23H19Cl2N5O2
|
2
|
| 1 |
IC50 = 4897.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0385511
|
1-[4-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl]piperidin-4-ol
Show/Hide
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C26H27FN6O
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1
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| 1 |
IC50 = 5000 nM
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CP0667774
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N-(3,5-dimethoxyphenyl)-3-(1-(2-methoxyethyl)-1H-pyrazol-4-yl)-N-((3-methylisoxazol-5-yl)methyl)quinoxalin-6-amine
Show/Hide
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C27H28N6O4
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2
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| 1 |
IC50 = 5011.87 nM
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| 2 |
IC50 > 10000 nM
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CP0701248
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N-((1H-pyrrolo[3,2-b]pyridin-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H25N7O2
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2
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| 1 |
IC50 = 5011.87 nM
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| 2 |
IC50 > 10000 nM
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CP0707093
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N-(3,5-dimethoxyphenyl)-N-(3-(4-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C29H26N6O3
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2
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| 1 |
IC50 = 5011.87 nM
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| 2 |
IC50 = 5370.32 nM
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CP0795336
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N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)-2,2,2-trifluoroacetamide
Show/Hide
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C24H23F3N6O3
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2
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| 1 |
IC50 = 5011.87 nM
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| 2 |
IC50 > 10000 nM
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CP0649800
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(3-methoxy-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)phenyl)(pyrrolidin-1-yl)methanone
Show/Hide
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C31H37N7O2
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2
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| 1 |
IC50 = 5128.61 nM
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| 2 |
IC50 > 10000 nM
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CP0701300
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4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)picolinonitrile
Show/Hide
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C29H23N7O2
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2
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| 1 |
IC50 = 5128.61 nM
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| 2 |
IC50 = 6165.95 nM
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CP0735326
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1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(2,2,2-trifluoroethylamino)propan-2-ol
Show/Hide
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C25H27F3N6O3
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2
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| 1 |
IC50 = 5128.61 nM
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| 2 |
IC50 > 10000 nM
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CP0508946
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N-(1H-indazol-6-yl)-6,7-dimethoxyquinazolin-4-amine
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C17H15N5O2
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1
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| 1 |
IC50 = 5200 nM
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CP0664721
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2-(4-(7-((3,5-dimethoxyphenyl)((3-methylisoxazol-5-yl)methyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
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C26H26N6O4
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2
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| 1 |
IC50 = 5248.07 nM
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| 2 |
IC50 > 10000 nM
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CP0672775
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-((1-methylpiperidin-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C30H36N6O2
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2
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| 1 |
IC50 = 5248.07 nM
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| 2 |
IC50 = 5495.41 nM
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CP0673334
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(S)-1-(2-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)ethyl)pyrrolidine-3-carbonitrile
Show/Hide
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C26H27N7O2
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2
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| 1 |
IC50 = 5248.07 nM
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| 2 |
IC50 > 10000 nM
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CP0692230
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(2S)-3-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}propane-1,2-diol
Show/Hide
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C23H25N5O4
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2
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| 1 |
IC50 = 5248.07 nM
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| 2 |
IC50 > 10000 nM
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CP0692265
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N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-(2,2,2-trifluoroethyl)ethane-1,2-diamine
Show/Hide
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C24H25F3N6O2
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2
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| 1 |
IC50 = 5248.07 nM
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| 2 |
IC50 > 10000 nM
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CP0698839
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Ethyl 1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidine-4-carboxylate
Show/Hide
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C30H36N6O4
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2
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| 1 |
IC50 = 5248.07 nM
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| 2 |
IC50 > 10000 nM
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CP0707089
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N1-(3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine hydrochloride
Show/Hide
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C27H33ClF3N7O2
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2
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| 1 |
IC50 = 5248.07 nM
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| 2 |
IC50 > 10000 nM
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CP0751773
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N-(3-(3,3-difluoropyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
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C27H31ClF2N6O2
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2
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| 1 |
IC50 = 5248.07 nM
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| 2 |
IC50 > 10000 nM
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CP0673336
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3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-ol
Show/Hide
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C23H22F3N5O3
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2
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| 1 |
IC50 = 5370.32 nM
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| 2 |
IC50 > 10000 nM
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CP0686573
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N-(3,5-dimethoxyphenyl)-N-(3-(4-methoxypyrimidin-2-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H29N7O3
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2
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| 1 |
IC50 = 5370.32 nM
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| 2 |
IC50 > 10000 nM
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CP0701256
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H32N6O2
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2
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| 1 |
IC50 = 5370.32 nM
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| 2 |
IC50 = 5495.41 nM
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CP0701295
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3-methoxy-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(2,2,2-trifluoroethylamino)propyl)amino)phenol
Show/Hide
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C24H25F3N6O2
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2
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| 1 |
IC50 = 5370.32 nM
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| 2 |
IC50 > 10000 nM
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CP0702096
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(piperidin-4-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
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C30H37ClN6O2
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1
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| 1 |
IC50 = 5370.32 nM
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CP0404583
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2-chloro-3-[(6,7-dimethoxyquinazolin-4-yl)amino]-4-fluorophenol
Show/Hide
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C16H13ClFN3O3
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1
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| 1 |
IC50 = 5400 nM
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CP0701263
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-((4-methoxypiperidin-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C30H36N6O3
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2
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| 1 |
IC50 = 5495.41 nM
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| 2 |
IC50 = 7244.36 nM
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CP0649784
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N1-(2-aminobenzyl)-N2-(3,5-dimethoxycyclohexa-2,4-dienyl)-N1-isopropyl-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
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C32H39N7O2
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2
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| 1 |
IC50 = 5495.41 nM
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| 2 |
IC50 > 10000 nM
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CP0649799
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl methylcarbamate
Show/Hide
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C24H26N6O4
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2
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| 1 |
IC50 = 5495.41 nM
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| 2 |
IC50 > 10000 nM
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CP0664717
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-2-yl)methyl)quinoxalin-6-amine
Show/Hide
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C25H27N5O3
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2
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| 1 |
IC50 = 5495.41 nM
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| 2 |
IC50 > 10000 nM
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CP0664740
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N-(3,5-dimethoxyphenyl)-N-(2-ethoxyethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C24H27N5O3
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2
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| 1 |
IC50 = 5495.41 nM
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| 2 |
IC50 > 10000 nM
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CP0686853
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1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-ol
Show/Hide
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C24H27N5O4
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2
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| 1 |
IC50 = 5495.41 nM
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| 2 |
IC50 > 10000 nM
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CP0409941
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4-fluoro-3-[[6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
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C23H27FN4O3
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1
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| 1 |
IC50 = 5600 nM
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CP0649796
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1-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-3-(piperidin-1-yl)propan-2-ol
Show/Hide
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C31H38N6O3
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2
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| 1 |
IC50 = 5623.41 nM
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| 2 |
IC50 = 5754.4 nM
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CP0850942
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(methylamino)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C26H30N6O2
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2
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| 1 |
IC50 = 5623.41 nM
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| 2 |
IC50 = 7079.46 nM
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CP0672889
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(R)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-yl acetate
Show/Hide
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C25H24F3N5O4
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2
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| 1 |
IC50 = 5623.41 nM
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| 2 |
IC50 > 10000 nM
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CP0672902
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(piperazin-1-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
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C29H36ClN7O2
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2
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| 1 |
IC50 = 5623.41 nM
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| 2 |
IC50 = 6165.95 nM
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CP0692272
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2-(4-(7-((3,5-dimethoxyphenyl)(3-(isopropylamino)propyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
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C28H35N7O3
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2
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| 1 |
IC50 = 5623.41 nM
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| 2 |
IC50 > 10000 nM
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CP0717313
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(4-methylpyridin-2-yl)propyl)quinoxalin-6-amine
Show/Hide
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C29H30N6O2
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2
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| 1 |
IC50 = 5623.41 nM
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| 2 |
IC50 > 10000 nM
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CP0756691
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(R/S)-1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidine-3-carbonitrile
Show/Hide
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C28H31N7O2
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2
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| 1 |
IC50 = 5623.41 nM
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| 2 |
IC50 > 10000 nM
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CP0771748
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3-((2-aminoethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
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C23H25N7O2
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2
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| 1 |
IC50 = 5623.41 nM
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| 2 |
IC50 > 10000 nM
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CP0409105
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3-[(6,7-dimethoxyquinazolin-4-yl)amino]benzene-1,2-diol
Show/Hide
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C16H15N3O4
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1
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| 1 |
IC50 = 5700 nM
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CP0649793
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(piperidin-4-ylmethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C29H34N6O2
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2
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| 1 |
IC50 = 5754.4 nM
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| 2 |
IC50 = 5888.44 nM
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CP0673350
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2-((3-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
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C21H21N5O2
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2
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| 1 |
IC50 = 5754.4 nM
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| 2 |
IC50 > 10000 nM
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CP0698830
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3-((3-fluoro-5-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
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C22H22FN5O2
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2
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| 1 |
IC50 = 5754.4 nM
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| 2 |
IC50 > 10000 nM
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CP0722354
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1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2-methylpropan-2-ol
Show/Hide
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C24H27N5O3
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2
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| 1 |
IC50 = 5754.4 nM
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| 2 |
IC50 > 10000 nM
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CP0726453
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2-(4-(7-((3,5-dimethoxyphenyl)(2-(methylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
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C25H29N7O3
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2
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| 1 |
IC50 = 5754.4 nM
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| 2 |
IC50 > 10000 nM
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CP0749415
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2-(3-((2-aminoethyl)(7-(1-methyl-1H-pyrazol-4-yl)quinoxalin-2-yl)amino)-5-fluorophenoxy)ethanol
Show/Hide
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C22H23FN6O2
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2
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| 1 |
IC50 = 5754.4 nM
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| 2 |
IC50 > 10000 nM
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CP0799271
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(Z)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-2-one oxime
Show/Hide
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C23H24N6O3
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2
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| 1 |
IC50 = 5754.4 nM
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| 2 |
IC50 > 10000 nM
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CP0667765
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methyl 2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)pyrimidine-4-carboxylate
Show/Hide
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C29H25N7O4
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2
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| 1 |
IC50 = 5888.44 nM
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| 2 |
IC50 = 6456.54 nM
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CP0704629
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2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-2-methyl-1-(piperazin-1-yl)propan-1-one
Show/Hide
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C31H37N7O3
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2
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| 1 |
IC50 = 5888.44 nM
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| 2 |
IC50 = 7585.78 nM
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CP0688427
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N-(3,5-Dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(pyrazin-2-ylmethyl)quinoxalin-6-amine
Show/Hide
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C25H23N7O2
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2
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| 1 |
IC50 = 5888.44 nM
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| 2 |
IC50 > 10000 nM
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CP0831842
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N-{3,5-Bis[(2H3)methyloxy]phenyl}-3-[1-(1-methylethyl)-1H-pyrazol-4-yl]-N-(3-pyridin-4-ylprop-2-yn-1-yl)quinoxalin-6-amine
Show/Hide
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C30H28N6O2
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2
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| 1 |
IC50 = 5888.44 nM
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| 2 |
IC50 = 7244.36 nM
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CP0856841
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1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methylbutan-2-ol
Show/Hide
|
C25H29N5O3
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2
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| 1 |
IC50 = 5888.44 nM
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| 2 |
IC50 > 10000 nM
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CP0863057
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N-(3,5-dimethoxyphenyl)-N-(2-((3R,5S)-3,5-dimethylpiperidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O2
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2
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| 1 |
IC50 = 5888.44 nM
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| 2 |
IC50 > 10000 nM
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CP0664743
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(S)-N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C23H26N6O2
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2
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| 1 |
IC50 = 6025.6 nM
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| 2 |
IC50 > 10000 nM
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CP0692235
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(R)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(2,2,2-trifluoroethylamino)propan-2-ol
Show/Hide
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C25H27F3N6O3
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2
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| 1 |
IC50 = 6025.6 nM
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| 2 |
IC50 > 10000 nM
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CP0700936
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydro-2H-pyran-4-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C26H29N5O3
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2
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| 1 |
IC50 = 6025.6 nM
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| 2 |
IC50 > 10000 nM
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CP0701267
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2-(4-(7-(((5-chlorothiophen-2-yl)methyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C26H24ClN5O3S
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2
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| 1 |
IC50 = 6025.6 nM
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| 2 |
IC50 > 10000 nM
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CP0704127
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3-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1-methyl-1H-pyrazol-5-yl)propan-1-ol
Show/Hide
|
C25H29N5O4
|
2
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| 1 |
IC50 = 6025.6 nM
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| 2 |
IC50 > 10000 nM
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CP0748515
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(Z)-N-(3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)allyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H28N6O3
|
2
|
| 1 |
IC50 = 6025.6 nM
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| 2 |
IC50 > 10000 nM
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CP0822984
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(E)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-one oxime
Show/Hide
|
C24H26N6O4
|
2
|
| 1 |
IC50 = 6025.6 nM
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| 2 |
IC50 > 10000 nM
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CP0664748
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N1-(3,5-dichlorophenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C23H24Cl2N6
|
2
|
| 1 |
IC50 = 6165.95 nM
|
|
|
| 2 |
IC50 = 6456.54 nM
|
|
|
|
CP0692457
|
2-(3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)-5-methoxyphenoxy)ethanol
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 6165.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704711
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrimidin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C27H23N7O2
|
2
|
| 1 |
IC50 = 6165.95 nM
|
|
|
| 2 |
IC50 = 9120.11 nM
|
|
|
|
CP0708029
|
N-(3,5-dimethoxyphenyl)-N-(3-(1-methyl-1H-imidazol-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H25N7O2
|
2
|
| 1 |
IC50 = 6165.95 nM
|
|
|
| 2 |
IC50 >= 10000 nM
|
|
|
|
CP0726443
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(pyrimidin-2-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C25H23N7O2
|
2
|
| 1 |
IC50 = 6165.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744815
|
N-(3,5-dimethoxyphenyl)-N-(2-((2S,6R)-2,6-dimethylmorpholino)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O3
|
2
|
| 1 |
IC50 = 6165.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672783
|
2-(4-(2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethyl)piperazin-1-yl)ethanol hydrochloride
Show/Hide
|
C31H40ClN7O3
|
2
|
| 1 |
IC50 = 6309.57 nM
|
|
|
| 2 |
IC50 = 9549.93 nM
|
|
|
|
CP0147358
|
N-[3-[[1-(6-aminopyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-3,5-dichlorobenzamide
Show/Hide
|
C25H19Cl2N7O
|
1
|
| 1 |
IC50 = 6365 nM
|
|
|
|
CP0864935
|
N-(3,5-dimethoxyphenyl)-N-(2-((3R,5R)-3,5-dimethylpiperidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 6456.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0395047
|
6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]-3-pyridin-2-ylimidazo[1,2-b]pyridazine
Show/Hide
|
C21H18FN5
|
1
|
| 1 |
IC50 = 6500 nM
|
|
|
|
CP0576189
|
1-[4-[3-[4-amino-5-(4-hydroxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
Show/Hide
|
C22H26N6O2
|
1
|
| 1 |
IC50 = 6500 nM
|
|
|
|
CP0664742
|
(3-((3-hydroxypropyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenyl)(pyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C27H31ClN6O3
|
2
|
| 1 |
IC50 = 6606.93 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664768
|
(R)-3-[{3-[1-(3-Aminopropyl)-1H-pyrazol-4-yl]quinoxalin-6-yl}(3,5-dimethoxyphenyl)amino]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C25H27F3N6O3
|
2
|
| 1 |
IC50 = 6606.93 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692273
|
3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3-hydroxypropyl)amino)-5-methoxyphenol
Show/Hide
|
C21H21N5O3
|
2
|
| 1 |
IC50 = 6606.93 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717321
|
N-allyl-N-(3-fluoro-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C22H20FN5O
|
2
|
| 1 |
IC50 = 6606.93 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0749418
|
3-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)oxazolidin-2-one
Show/Hide
|
C25H26N6O4
|
2
|
| 1 |
IC50 = 6606.93 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667760
|
(R)-1-((3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)-3-methoxypropan-2-ol hydrochloride
Show/Hide
|
C26H33ClN6O4
|
2
|
| 1 |
IC50 = 6760.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672834
|
N-(2,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H33ClN6O2
|
2
|
| 1 |
IC50 = 6760.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692297
|
N-(3,5-dimethoxyphenyl)-N-(3-((2S,6R)-2,6-dimethylmorpholino)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O3
|
2
|
| 1 |
IC50 = 6760.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0735247
|
3-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)azetidin-3-ol
Show/Hide
|
C26H26N6O3
|
2
|
| 1 |
IC50 = 6760.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667761
|
(S)-1-((3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)-3-methoxypropan-2-ol hydrochloride
Show/Hide
|
C26H33ClN6O4
|
2
|
| 1 |
IC50 = 6918.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744804
|
(S)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-yl acetate
Show/Hide
|
C26H29N5O5
|
2
|
| 1 |
IC50 = 6918.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0772378
|
N'-[3-fluoro-5-(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
Show/Hide
|
C21H21FN6O
|
2
|
| 1 |
IC50 = 6918.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672828
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H30N6O3
|
2
|
| 1 |
IC50 = 7079.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692226
|
N-(3-(3,3-difluoropyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C32H39ClF2N6O3
|
2
|
| 1 |
IC50 = 7079.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701306
|
N-(3,5-dimethoxyphenyl)-N-(3-(4-ethoxypyrimidin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H27N7O3
|
2
|
| 1 |
IC50 = 7079.46 nM
|
|
|
| 2 |
IC50 = 8128.31 nM
|
|
|
|
CP0707094
|
N-(3,5-dimethoxyphenyl)-N-(prop-2-ynyl)-3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H29N5O3
|
2
|
| 1 |
IC50 = 7079.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0767027
|
2-(4-(7-((3-aminopropyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C25H29N7O3
|
2
|
| 1 |
IC50 = 7079.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0850937
|
1-(3,3-difluoropyrrolidin-1-yl)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-2-ol hydrochloride
Show/Hide
|
C27H31ClF2N6O3
|
2
|
| 1 |
IC50 = 7079.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649804
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C23H21N5O2
|
2
|
| 1 |
IC50 = 7244.36 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664745
|
(R)-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 7244.36 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664786
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H28N6O4S
|
2
|
| 1 |
IC50 = 7244.36 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672907
|
N-(2-(4-aminopiperidin-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H33N7O2
|
2
|
| 1 |
IC50 = 7244.36 nM
|
|
|
| 2 |
IC50 >= 10000 nM
|
|
|
|
CP0704712
|
5-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2-methylpent-3-yn-2-ol
Show/Hide
|
C26H27N5O3
|
2
|
| 1 |
IC50 = 7244.36 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707092
|
(S)-3-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C25H26F3N5O3
|
2
|
| 1 |
IC50 = 7244.36 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667755
|
(R/S)-3-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)pyrrolidin-3-ol
Show/Hide
|
C27H28N6O3
|
2
|
| 1 |
IC50 = 7413.1 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692270
|
3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenol
Show/Hide
|
C23H23N5O2
|
2
|
| 1 |
IC50 = 7413.1 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704647
|
N1-(3-fluoro-5-methoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C21H21FN6O
|
2
|
| 1 |
IC50 = 7413.1 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726455
|
N-(2-(4,4-difluoropiperidin-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H30F2N6O2
|
2
|
| 1 |
IC50 = 7413.1 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657946
|
N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(2,2,2-trifluoroethyl)propane-1,2-diamine
Show/Hide
|
C25H27F3N6O2
|
2
|
| 1 |
IC50 = 7585.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664769
|
(R)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propane-1,2-diol
Show/Hide
|
C23H25N5O4
|
2
|
| 1 |
IC50 = 7585.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672903
|
3-((3-fluoro-5-methoxyphenyl)(3-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C23H24FN5O3
|
2
|
| 1 |
IC50 = 7585.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686564
|
(2S*)-3-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C23H22F3N5O3
|
2
|
| 1 |
IC50 = 7585.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0690288
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-(methylamino)pyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C29H27N7O2
|
2
|
| 1 |
IC50 = 7762.47 nM
|
|
|
| 2 |
IC50 = 8128.31 nM
|
|
|
|
CP0690289
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-isopropylpropanamide
Show/Hide
|
C26H30N6O3
|
2
|
| 1 |
IC50 = 7762.47 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692286
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((2-(pyridin-4-yl)cyclopropyl)methyl)quinoxalin-6-amine
Show/Hide
|
C29H28N6O2
|
2
|
| 1 |
IC50 = 7762.47 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698846
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(5-((dimethylamino)methyl)-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-isopropylethane-1,2-diamine
Show/Hide
|
C28H37N7O2
|
2
|
| 1 |
IC50 = 7762.47 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0700917
|
N-(3,5-dimethoxyphenyl)-N-(3-(4-isopropoxypyrimidin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C30H29N7O3
|
2
|
| 1 |
IC50 = 7762.47 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0701288
|
N-((6-chloropyridin-3-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H23ClN6O2
|
2
|
| 1 |
IC50 = 7762.47 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701296
|
(1S,4S)-tert-butyl 5-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
Show/Hide
|
C32H39N7O4
|
2
|
| 1 |
IC50 = 7762.47 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701305
|
(Z)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(4-methylpyridin-2-yl)allyl)quinoxalin-6-amine
Show/Hide
|
C29H28N6O2
|
2
|
| 1 |
IC50 = 7762.47 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726424
|
N-(3,5-dimethoxyphenyl)-N-(3-(4-ethylpyrimidin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H27N7O2
|
2
|
| 1 |
IC50 = 7762.47 nM
|
|
|
| 2 |
IC50 = 8511.38 nM
|
|
|
|
CP0667779
|
3-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)propane-1,2-diol
Show/Hide
|
C26H29N5O4
|
2
|
| 1 |
IC50 = 7943.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0803486
|
2-((3,5-dimethoxyphenyl)(3-(1,3,5-trimethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C24H27N5O3
|
2
|
| 1 |
IC50 = 7943.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664718
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-(pyrrolidin-1-yl)ethyl)acetamide
Show/Hide
|
C31H37N7O3
|
2
|
| 1 |
IC50 = 8128.31 nM
|
|
|
| 2 |
IC50 = 8709.64 nM
|
|
|
|
CP0664764
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(5-ethyl-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-(2,2,2-trifluoroethyl)ethane-1,2-diamine
Show/Hide
|
C26H29F3N6O2
|
2
|
| 1 |
IC50 = 8128.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702108
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(pyridin-4-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C26H24N6O2
|
2
|
| 1 |
IC50 = 8128.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702260
|
1-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)-2-methylpropan-2-ol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 8128.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0166282
|
3-(1-(6-amino-5-methylpyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide
Show/Hide
|
C27H22F3N7O
|
1
|
| 1 |
IC50 = 8181 nM
|
|
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CP0672784
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H35ClN6O2
|
2
|
| 1 |
IC50 = 8317.64 nM
|
|
|
| 2 |
IC50 = 8912.51 nM
|
|
|
|
CP0688466
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H25N5O2
|
2
|
| 1 |
IC50 = 8317.64 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0690292
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(3-(2-(methylsulfonyl)ethylamino)propyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O4S
|
2
|
| 1 |
IC50 = 8317.64 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0748512
|
N-(3-(3-aminopyridin-2-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O2
|
2
|
| 1 |
IC50 = 8317.64 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0775908
|
(R)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-yl acetate
Show/Hide
|
C26H29N5O5
|
2
|
| 1 |
IC50 = 8317.64 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692261
|
(R)-N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 8511.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704137
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(4-methylpyrimidin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O2
|
2
|
| 1 |
IC50 = 8511.38 nM
|
|
|
| 2 |
IC50 = 8912.51 nM
|
|
|
|
CP0707217
|
N-(3,5-Dimethoxyphenyl)-N-{3-[1-(1-methylethyl)-1H-pyrazol-4-yl]quinoxalin-6-yl}-N'-(2,2,2-trifluoroethyl)propane-1,3-diamine hydrochloride
Show/Hide
|
C27H32ClF3N6O2
|
2
|
| 1 |
IC50 = 8511.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0720061
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C25H30N6O4S
|
2
|
| 1 |
IC50 = 8511.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0804304
|
2-[4-(7-{(Cyclopropylmethyl)[3-(2-hydroxyethoxy)-5-methoxyphenyl]amino}quinoxalin-2-yl)-1H-pyrazol-1-yl]ethanol hydrochloride
Show/Hide
|
C26H30ClN5O4
|
2
|
| 1 |
IC50 = 8511.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0850935
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H33N5O3
|
2
|
| 1 |
IC50 = 8511.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0138866
|
1-[4-[3-[4-amino-5-(2-fluoro-5-hydroxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
Show/Hide
|
C22H25FN6O2
|
2
|
| 1 |
IC50 = 8700 nM
|
|
|
| 2 |
IC50 > 7800 nM
|
|
|
|
CP0667757
|
N-(2,6-dichloro-3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H24Cl2N6O3
|
2
|
| 1 |
IC50 = 8709.64 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667778
|
N-[2-[4-[7-[N-(cyclopropylmethyl)-3,5-dimethoxy-anilino]quinoxalin-2-yl]pyrazol-1-yl]ethyl]methanesulfonamide
Show/Hide
|
C26H30N6O4S
|
2
|
| 1 |
IC50 = 8709.64 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698826
|
N-(3,5-dimethoxyphenyl)-N-((1-isopropylpiperidin-4-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O2
|
2
|
| 1 |
IC50 = 8709.64 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0269791
|
3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-phenylbenzamide
Show/Hide
|
C25H21N7O
|
1
|
| 1 |
IC50 = 8817 nM
|
|
|
|
CP0866314
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-(2,2,6,6-tetramethylpiperidin-4-yl)ethane-1,2-diamine
Show/Hide
|
C31H41N7O2
|
2
|
| 1 |
IC50 = 8912.51 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0795293
|
(2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)pyridin-4-yl)methanol
Show/Hide
|
C29H26N6O3
|
2
|
| 1 |
IC50 = 8912.51 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0165616
|
N-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N',N'-dimethylpropane-1,3-diamine
Show/Hide
|
C18H21N5O2
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0289192
|
N-[3-[[1-(6-chloropyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C26H18ClF3N6O
|
1
|
| 1 |
IC50 = 9069 nM
|
|
|
|
CP0701298
|
N-(3,5-Dimethoxyphenyl)-N-[3-(4-methoxypyrimidin-2-yl)prop-2-yn-1-yl]-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O3
|
2
|
| 1 |
IC50 = 9120.11 nM
|
|
|
| 2 |
IC50 >= 10000 nM
|
|
|
|
CP0657878
|
N-(3-(3,3-difluoropyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H29ClF2N6O2
|
2
|
| 1 |
IC50 = 9120.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688424
|
N-(3-(3,3-difluoropyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H28F2N6O2
|
2
|
| 1 |
IC50 = 9120.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0690265
|
(6-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)pyridin-2-yl)methanol
Show/Hide
|
C29H26N6O3
|
2
|
| 1 |
IC50 = 9120.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692228
|
N1-(3-ethoxy-5-fluorophenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C22H23FN6O
|
2
|
| 1 |
IC50 = 9120.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692277
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-methoxyphenyl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C30H27N5O3
|
2
|
| 1 |
IC50 = 9120.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701282
|
2-(5-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)-1,3,4-oxadiazol-2-ylamino)ethanol
Show/Hide
|
C25H26N8O4
|
2
|
| 1 |
IC50 = 9120.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707097
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-fluoropyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H23FN6O2
|
2
|
| 1 |
IC50 = 9332.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688373
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N,N-dimethylacetamide
Show/Hide
|
C27H30N6O3
|
2
|
| 1 |
IC50 = 9549.93 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649797
|
2-(3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenoxy)ethanol
Show/Hide
|
C25H27N5O3
|
2
|
| 1 |
IC50 = 9772.37 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701268
|
2-(3-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)azetidin-1-yl)ethanol
Show/Hide
|
C28H32N6O3
|
2
|
| 1 |
IC50 = 9772.37 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704644
|
N-(3,5-dimethoxyphenyl)-N-((1-methyl-1H-imidazol-2-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C25H25N7O2
|
2
|
| 1 |
IC50 = 9772.37 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0822997
|
N-[3-(6-Aminopyridin-2-yl)prop-2-yn-1-yl]-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O2
|
2
|
| 1 |
IC50 = 9772.37 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0147360
|
N-[4-methyl-3-[[1-(6-morpholin-4-ylpyrimidin-4-yl)benzimidazol-2-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H26F3N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0166377
|
N-[3-[[1-(6-methoxypyrimidin-4-yl)benzimidazol-2-yl]amino]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C27H21F3N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0281287
|
3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-carbamoylphenyl)-4-methylbenzamide
Show/Hide
|
C26H22N8O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385517
|
2-chloro-3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Show/Hide
|
C16H14ClN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0391618
|
3-[(6,7-dimethoxyquinazolin-4-yl)-methylamino]phenol
Show/Hide
|
C17H17N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0404687
|
3-[(6,7-dimethoxyquinazolin-4-yl)amino]-5-fluoro-2-methylphenol
Show/Hide
|
C17H16FN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409353
|
2-bromo-3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Show/Hide
|
C16H14BrN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0414851
|
3-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenol
Show/Hide
|
C17H17N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0424710
|
3-[(6,7-dimethoxyquinazolin-4-yl)amino]-4-fluoro-2-methylphenol
Show/Hide
|
C17H16FN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0519309
|
2,4-dichloro-3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Show/Hide
|
C16H13Cl2N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0520412
|
1-(6,7-dimethoxyquinazolin-4-yl)-2,3-dihydroindol-4-ol
Show/Hide
|
C18H17N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0558353
|
4-chloro-3-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenol
Show/Hide
|
C17H16ClN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0322285
|
N-(3H-benzimidazol-5-yl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C17H15N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0376866
|
4-fluoro-3-[[6-methoxy-7-[2-(methylamino)ethoxy]quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C19H21FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0376867
|
4-fluoro-3-[[6-methoxy-7-(2-piperidin-1-ylethoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C23H27FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0376868
|
3-[[7-[2-(1,1-dioxo-1,4-thiazinan-4-yl)ethoxy]-6-methoxyquinazolin-4-yl]amino]-4-fluoro-2-methylphenol
Show/Hide
|
C22H25FN4O5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0376869
|
4-fluoro-3-[[6-methoxy-7-[2-[2-(trifluoromethyl)pyrrolidin-1-yl]ethoxy]quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C23H24F4N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0376870
|
4-fluoro-3-[[6-methoxy-7-[(1-methylimidazol-2-yl)methoxy]quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C21H20FN5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0382471
|
4-fluoro-3-[[6-methoxy-7-(oxolan-2-ylmethoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C21H22FN3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0407452
|
3-[[7-(3-aminopropoxy)-6-methoxyquinazolin-4-yl]amino]-4-fluoro-2-methylphenol
Show/Hide
|
C19H21FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409936
|
4-fluoro-3-[[6-methoxy-7-(2-pyrrolidin-1-ylethoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C22H25FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409937
|
4-fluoro-3-[[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C24H29FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409938
|
4-fluoro-3-[[6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C24H30FN5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409939
|
4-fluoro-3-[[6-methoxy-7-[3-[2-(trifluoromethyl)pyrrolidin-1-yl]propoxy]quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C24H26F4N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0420095
|
4-fluoro-3-[[6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C23H27FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0420096
|
4-fluoro-3-[[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C23H27FN4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0420097
|
4-fluoro-3-[[7-[2-(3-fluoropyrrolidin-1-yl)ethoxy]-6-methoxyquinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C22H24F2N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0420098
|
4-fluoro-3-[[6-methoxy-7-(pyridin-3-ylmethoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C22H19FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0447953
|
4-fluoro-3-[[6-methoxy-7-(3-methoxypropoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C20H22FN3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0452542
|
4-fluoro-3-[[6-methoxy-7-(3-piperazin-1-ylpropoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C23H28FN5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0452543
|
3-[[7-[3-(1,4-diazepan-1-yl)propoxy]-6-methoxyquinazolin-4-yl]amino]-4-fluoro-2-methylphenol
Show/Hide
|
C24H30FN5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459553
|
N-(1H-indol-6-yl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C18H16N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459554
|
3-[[7-(2-aminoethoxy)-6-methoxyquinazolin-4-yl]amino]-4-fluoro-2-methylphenol
Show/Hide
|
C18H19FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459555
|
3-[[7-[2-(dimethylamino)ethoxy]-6-methoxyquinazolin-4-yl]amino]-4-fluoro-2-methylphenol
Show/Hide
|
C20H23FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459556
|
4-fluoro-3-[[6-methoxy-7-(2-piperazin-1-ylethoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C22H26FN5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459557
|
4-fluoro-3-[[6-methoxy-7-[2-(4-methylpiperazin-1-yl)ethoxy]quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C23H28FN5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459558
|
4-fluoro-3-[[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C19H20FN3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0508944
|
N-[3-(difluoromethyl)phenyl]-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C17H15F2N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0508948
|
4-fluoro-3-[[6-methoxy-7-(2-morpholin-4-ylethoxy)quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C22H25FN4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0542135
|
N-(1H-indazol-4-yl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C17H15N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0542136
|
3-[[7-[3-(1,1-dioxo-1,4-thiazinan-4-yl)propoxy]-6-methoxyquinazolin-4-yl]amino]-4-fluoro-2-methylphenol
Show/Hide
|
C23H27FN4O5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0554858
|
3-[[7-[2-(1,4-diazepan-1-yl)ethoxy]-6-methoxyquinazolin-4-yl]amino]-4-fluoro-2-methylphenol
Show/Hide
|
C23H28FN5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0554859
|
4-fluoro-3-[[6-methoxy-7-[(5-methyl-1,2,4-oxadiazol-3-yl)methoxy]quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C20H18FN5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0570907
|
US9353116, Fig. 16, Compound 2
Show/Hide
|
C17H18N4O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0570908
|
N-(1H-indol-4-yl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C18H16N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0570909
|
4-fluoro-3-[[6-methoxy-7-[3-(methylamino)propoxy]quinazolin-4-yl]amino]-2-methylphenol
Show/Hide
|
C20H23FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0570910
|
3-[[7-[3-(dimethylamino)propoxy]-6-methoxyquinazolin-4-yl]amino]-4-fluoro-2-methylphenol
Show/Hide
|
C21H25FN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0574183
|
N-(1H-indazol-5-yl)-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C17H15N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0305157
|
1-[4-(5-amino-1,2-oxazol-3-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C17H13F3N4O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0499810
|
1-[4-(3-amino-1H-pyrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C17H14F3N5O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0509087
|
N-[3-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-1,2-oxazol-5-yl]cyclopropanecarboxamide
Show/Hide
|
C21H23N5O4
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0649783
|
1-(4-((3-aminopropyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2,6-dimethoxyphenyl)-2,2,2-trifluoroethanol
Show/Hide
|
C25H27F3N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649785
|
1-(1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methylbutan-2-yloxy)-3-methylbutan-2-ol
Show/Hide
|
C30H39N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649787
|
3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)-N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)quinoxalin-6-amine
Show/Hide
|
C26H30N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649788
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C25H27N5O3
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 >= 10000 nM
|
|
|
|
CP0649792
|
ethyl 2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)acetate
Show/Hide
|
C24H25N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649803
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-1-(3-hydroxypyrrolidin-1-yl)ethanone
Show/Hide
|
C29H32N6O4
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0649814
|
N-(3-(1,3-dioxolan-2-yl)-5-methoxyphenyl)-N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H27N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0657066
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C21H23ClN6O2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 >= 10000 nM
|
|
|
|
CP0657861
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(2-(pyrrolidin-1-yl)ethyl)acetamide
Show/Hide
|
C28H33N7O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0657869
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-isopropylpropanamide
Show/Hide
|
C26H30N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0657883
|
N1-(3,5-dichlorophenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C23H21Cl2F3N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0657942
|
2-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3-fluoro-5-methoxyphenyl)amino)ethanol
Show/Hide
|
C20H18FN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664657
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-hydroxyethyl)-2-methylpropanamide
Show/Hide
|
C29H34N6O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664715
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-isobutyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H31N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664751
|
2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)isonicotinonitrile
Show/Hide
|
C29H23N7O2
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0664765
|
2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)isonicotinamide
Show/Hide
|
C29H25N7O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664767
|
methyl 2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)nicotinate
Show/Hide
|
C30H26N6O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664776
|
N-((6-bromopyridin-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H23BrN6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664782
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)-N2-methylethane-1,2-diamine
Show/Hide
|
C22H24N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667759
|
N-(3,5-dimethoxyphenyl)-N-((4,6-dimethoxypyrimidin-2-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H27N7O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667767
|
(R/S)-3-((2,3-dihydroxypropyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C24H26N6O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667772
|
N-(3,5-dimethoxyphenyl)-N-((6-(dimethylamino)pyridin-2-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H29N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667775
|
1-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-2-methylpropan-2-ol
Show/Hide
|
C27H31N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667776
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-methoxyethyl)-2-methylpropanamide
Show/Hide
|
C30H36N6O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672724
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C24H25F3N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672829
|
N-(3-cyclohexylprop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H31N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672833
|
3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxybenzonitrile
Show/Hide
|
C24H22N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672845
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propanamide
Show/Hide
|
C23H24N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672898
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(2,4,4-trimethyl-4,5-dihydro-1H-imidazol-1-yl)ethyl)quinoxalin-6-amine
Show/Hide
|
C28H33N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672900
|
N-(3-(3-aminophenyl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672904
|
2-(4-(7-((cyclopropylmethyl)(3-fluoro-5-methoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C24H24FN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0673321
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C28H31F3N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0673329
|
N-(3,5-dimethoxyphenyl)-N-((2-methylthiazol-4-yl)methyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H22N6O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0673345
|
N-(3,5-dimethoxyphenyl)-N-((1,5-dimethyl-1H-pyrazol-3-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H27N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0675666
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethylphosphonic acid hydrobromide
Show/Hide
|
C22H25BrN5O5P
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0686567
|
3-((3,5-dimethoxyphenyl)(3-(1,3,5-trimethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0686864
|
3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(2,2,2-trifluoroethylamino)propyl)amino)-5-methoxyphenol hydrochloride
Show/Hide
|
C23H24ClF3N6O2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 = 10232.93 nM
|
|
|
|
CP0688431
|
N-(3,5-dimethoxyphenyl)-N-(3-(5-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688434
|
2-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide
Show/Hide
|
C26H28N8O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688438
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-methoxypyrazin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688442
|
N-(cyclopropylmethyl)-N-(3-methoxy-5-(methoxymethyl)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C25H27N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688464
|
N-(3-(5H-pyrrolo[2,3-b]pyrazin-2-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H24N8O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0690287
|
N-(3-(5-aminopyrazin-2-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H24N8O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0690291
|
N-(2-methoxyethyl)-N-(3-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C22H23N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0690294
|
N-(cyclopropylmethyl)-N-(3-isopropoxy-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H30ClN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692260
|
N-(3,5-dimethoxyphenyl)-N-((1-ethyl-1H-imidazol-2-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H27N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692266
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-methoxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H29N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692268
|
N-(3,5-Dimethoxyphenyl)-N-[3-(3-methoxypyridin-2-yl)prop-2-yn-1-yl]-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692269
|
N-(3,5-dimethoxyphenyl)-N-(2-(2,5-dimethyl-1H-imidazol-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H29N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692274
|
N-(3,5-dimethoxyphenyl)-N-(2-fluoroethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C22H22FN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692282
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyridin-3-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C28H24N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692300
|
2-(4-(7-((3,5-dimethoxyphenyl)(2-(methylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C24H28N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692303
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(((1R,2R)-2-(pyridin-2-yl)cyclopropyl)methyl)quinoxalin-6-amine
Show/Hide
|
C29H28N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692460
|
N-((5-chlorothiophen-2-yl)methyl)-3-(1-((5-chlorothiophen-2-yl)methyl)-1H-pyrazol-4-yl)-N-(3,5-dimethoxyphenyl)quinoxalin-6-amine
Show/Hide
|
C29H23Cl2N5O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692461
|
N1-cyclopropyl-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C25H28N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0698824
|
N-(3,5-Dimethoxyphenyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]-N'-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C25H27F3N6O2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 >= 10000 nM
|
|
|
|
CP0698827
|
(E)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methylbutan-2-one oxime
Show/Hide
|
C25H28N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0698847
|
N-(3,5-dimethoxyphenyl)-3-(1-isopropyl-1H-pyrazol-4-yl)-N-(3-(3-methoxypyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C31H30N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0700930
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propanoic acid hydrochloride
Show/Hide
|
C23H24ClN5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0701252
|
(3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenyl)(pyrrolidin-1-yl)methanone
Show/Hide
|
C28H30N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0701259
|
N1-(3,5-dimethoxyphenyl)-N2-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0701261
|
3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)benzonitrile
Show/Hide
|
C23H20N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0701304
|
4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)tetrahydro-2H-pyran-4-ol
Show/Hide
|
C28H29N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0702428
|
N-((4-benzylmorpholin-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C32H34N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0702435
|
N-(cyclopropylmethyl)-N-(3-methoxy-5-(2-methoxyethyl)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H30ClN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0702438
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N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-(2,2,2-trifluoroethyl)propane-1,2-diamine
Show/Hide
|
C25H27F3N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704125
|
N-(3,5-dimethoxyphenyl)-N-(3-(2-methoxypyridin-4-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704126
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-phenylprop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C29H25N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704138
|
(S)-3-[{3-[1-(3-Aminopropyl)-1H-pyrazol-4-yl]quinoxalin-6-yl}(3,5-dimethoxyphenyl)amino]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C25H27F3N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704142
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-methylpyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704156
|
N-(cyclopropylmethyl)-N-(3-(difluoromethoxy)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H21F2N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704177
|
N-(2-chloro-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H30Cl2N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704631
|
N-(3-(cyclopropylmethoxy)-5-methoxyphenyl)-N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H30ClN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704632
|
N1-(3,5-dimethoxyphenyl)-N2-methyl-N1-(3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C25H30N6O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704713
|
N1-(3,4-difluoro-5-methoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine hydrochloride
Show/Hide
|
C24H24ClF5N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0707091
|
N-(2-(1H-pyrrol-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H26N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0707159
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-isopropylacetamide
Show/Hide
|
C25H28N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0707163
|
2-((3,5-dimethoxyphenyl)(3-(5-((dimethylamino)methyl)-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C25H30N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0707219
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(3-methoxypyridin-2-yl)acetamide
Show/Hide
|
C28H27N7O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0717784
|
N-(3,5-Dimethoxyphenyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
Show/Hide
|
C22H24N6O2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 >= 10000 nM
|
|
|
|
CP0717814
|
2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)benzonitrile
Show/Hide
|
C30H24N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0720052
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-(3,3,3-trifluoropropyl)ethane-1,2-diamine
Show/Hide
|
C25H27F3N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0726451
|
N-(cyclopropylmethyl)-N-(2,3-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H25N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0726452
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((5-methylisoxazol-3-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C25H24N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0726479
|
tert-butyl 4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)-4-hydroxypiperidine-1-carboxylate, oxalate salt
Show/Hide
|
C35H40N6O9
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0744801
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C28H24N6O2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 >= 10000 nM
|
|
|
|
CP0744807
|
N-(3,5-dimethoxyphenyl)-N-(2-(5-methyl-1H-pyrazol-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H27N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0744808
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H34N6O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0744812
|
N-(cyclopropylmethyl)-N-phenyl-3-(1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C21H20ClN5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0746842
|
N-(3,5-dimethoxyphenyl)-N-((6-methoxypyridin-2-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H26N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0775909
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C26H28N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0786936
|
N-(cyclopropylmethyl)-N-(3-((dimethylamino)methyl)-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H30N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0805838
|
N-((5-chlorothiophen-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H20ClN5O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0831841
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-fluoroethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C25H26FN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0841406
|
3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(2-(isopropylamino)ethyl)amino)-5-methoxyphenol hydrochloride
Show/Hide
|
C23H27ClN6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0848581
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-((trimethylsilyl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H33N5O2Si
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0864426
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1-(pyrrolidin-1-yl)ethanone
Show/Hide
|
C26H28N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0864428
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(2-hydroxyethyl)acetamide
Show/Hide
|
C24H26N6O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649782
|
N-(cyclopropylmethyl)-N-(3-((ethyl(methyl)amino)methyl)-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649790
|
2-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)isoindoline-1,3-dione
Show/Hide
|
C30H26N6O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649791
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N,2-dimethylpropanamide
Show/Hide
|
C28H32N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649795
|
N-(3-(aminomethyl)-5-methoxyphenyl)-N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C24H27ClN6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649798
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-hydroxyethyl)acetamide
Show/Hide
|
C27H30N6O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664656
|
4-((4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)methyl)piperidin-4-ol
Show/Hide
|
C29H34N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664722
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)acetic acid hydrochloride
Show/Hide
|
C22H22ClN5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664738
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H23N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664766
|
tert-butyl 4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)piperidine-1-carboxylate
Show/Hide
|
C33H38N6O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0664785
|
(S)-1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidine-2-carboxylic acid hydrochloride
Show/Hide
|
C27H31ClN6O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667762
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((1-methyl-1H-pyrrolo[3,2-b]pyridin-2-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C29H27N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667766
|
N-(2-(1H-pyrrol-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H27ClN6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667770
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(1-methyl-1H-pyrazol-4-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C27H25N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667771
|
2-((3,5-dimethoxycyclohexa-2,4-dienyl)(3-(1-methyl-3,5-bis(trifluoromethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C24H23F6N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667773
|
N-(cyclopropylmethyl)-N-(3-isopropoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C25H27N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667777
|
2-(4-(7-((3,5-dimethoxyphenyl)(2-(methylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide hydrochloride
Show/Hide
|
C25H30ClN7O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672780
|
3-((3-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C29H35N7O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672891
|
(E)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(4-methylpyridin-2-yl)allyl)quinoxalin-6-amine
Show/Hide
|
C29H28N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672897
|
N-(cyclopropylmethyl)-N-(3-methoxy-5-(trifluoromethyl)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H22F3N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672899
|
N-(3,5-dimethoxyphenyl)-N-(2-(3-methyl-1H-1,2,4-triazol-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C25H26N8O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672908
|
N-(cyclopropylmethyl)-N-(3-methoxy-5-vinylphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C25H26ClN5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0673323
|
2-(3-methoxy-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(2-(methylamino)ethyl)amino)phenoxy)ethanol hydrochloride
Show/Hide
|
C24H29ClN6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0673347
|
N1-(3-fluoro-5-methoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C24H24F4N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0675665
|
N-(cyclopropylmethyl)-N-(3-(ethoxymethyl)-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H29N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0683614
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(2,5-dimethoxyphenyl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C21H23ClN6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0686497
|
N-(3,5-dimethoxyphenyl)-N-(2-(2,4-dimethyl-1H-imidazol-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H30ClN7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688426
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(4-phenylbut-3-ynyl)quinoxalin-6-amine
Show/Hide
|
C30H27N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688430
|
N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-phenylquinoxalin-6-amine
Show/Hide
|
C22H21N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688439
|
(E)-N-(3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)allyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H28N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688449
|
N-(3,5-dimethoxyphenyl)-N-(dimethylsulfamoyl)-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C22H24N6O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0690540
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ethyl 2-(4-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetate
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C27H28N8O4
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1
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| 1 |
IC50 > 10000 nM
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CP0692218
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N1-(2,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
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C25H30N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0692271
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N-(3,5-dimethoxyphenyl)-N-((3-((isopropylamino)methyl)oxetan-3-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H34N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0692276
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6-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)picolinonitrile
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C29H23N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0692302
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2-((3,5-dimethoxycyclohexa-2,4-dienyl)(3-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
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C23H24F3N5O3
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1
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| 1 |
IC50 > 10000 nM
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CP0698817
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N-(3-(2-aminoethoxy)-5-methoxyphenyl)-N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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C25H28N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0698818
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N-benzyl-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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C27H25N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0698823
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2-((2,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol hydrochloride
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C22H24ClN5O3
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1
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| 1 |
IC50 > 10000 nM
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CP0700925
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N-(3-chloro-5-methoxyphenyl)-N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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C23H22ClN5O
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1
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| 1 |
IC50 > 10000 nM
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CP0701253
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3-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)benzonitrile
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C30H24N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0701254
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(((1S,2S)-2-(pyridin-2-yl)cyclopropyl)methyl)quinoxalin-6-amine
Show/Hide
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C29H28N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0701255
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N1-(3,5-dimethoxyphenyl)-N2-isopropyl-3-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)butane-1,2-diamine
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C28H36N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0701257
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N-((1,3-dioxolan-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C24H25N5O4
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1
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| 1 |
IC50 > 10000 nM
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CP0701260
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(3-morpholinopropyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
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C30H37ClN6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0701262
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)acetamide
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C22H22N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0701264
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N-((5-chlorothiophen-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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C25H22ClN5O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0701278
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2-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(2-chloro-5-methoxyphenyl)amino)ethanol hydrochloride
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C20H19Cl2N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0701294
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(S)-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
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C23H26N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0701308
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(4-methylpyridin-2-yl)acetamide
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C28H27N7O3
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1
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| 1 |
IC50 > 10000 nM
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CP0701311
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2-(3-((cyclopropylmethyl)(3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenoxy)ethanol
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C27H31N5O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0701312
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4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)piperidin-4-ol
Show/Hide
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C28H30N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0702094
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N-(3,5-dimethoxyphenyl)-N-(3-(2,6-dimethoxypyrimidin-4-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C29H27N7O4
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1
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| 1 |
IC50 > 10000 nM
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CP0702102
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N-(4-chlorobenzyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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C27H24ClN5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0702433
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N-(2-chlorobenzyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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C27H24ClN5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0704131
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1-(1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methylbutan-2-yloxy)-3-methylbutan-2-ol hydrochloride
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C30H40ClN5O4
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1
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| 1 |
IC50 > 10000 nM
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CP0704179
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N-(3-chlorobenzyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C27H24ClN5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0704630
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(S)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(pyrrolidin-2-ylmethyl)quinoxalin-6-amine
Show/Hide
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C25H28N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0704634
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2-(3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(cyclopropylmethyl)amino)-5-methoxyphenoxy)ethanol
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C24H25N5O3
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1
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| 1 |
IC50 > 10000 nM
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CP0704651
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3-((2-aminoethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenol
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C21H22N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0707088
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyridin-4-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
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C28H24N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0707090
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(5-methylpyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
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C29H26N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0707213
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2-(3-((2-aminoethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenoxy)ethanol hydrochloride
Show/Hide
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C23H27ClN6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0707222
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(methylsulfonyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C24H25N5O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0717312
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(R/S)-3-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)tetrahydrofuran-3-ol
Show/Hide
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C27H27N5O4
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1
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| 1 |
IC50 > 10000 nM
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CP0717315
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N-((1,4-dibenzylpiperazin-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C39H41N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0717317
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-methylacetamide
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C23H24N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0717813
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N-(3-(4-aminophenyl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C29H26N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0719253
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N-(3,5-dimethoxyphenyl)-N-(2-(2-methyl-1H-imidazol-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C26H27N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0719594
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4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-N,N-dimethyl-1H-pyrazole-1-sulfonamide
Show/Hide
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C25H28N6O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0720055
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2-(4-(3-((2-aminoethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-6-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
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C24H27N7O3
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1
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| 1 |
IC50 > 10000 nM
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CP0726426
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N-(3,5-dimethoxyphenyl)-3-(1-isobutyl-1H-pyrazol-4-yl)-N-(2-(5-methyl-1H-1,2,4-triazol-1-yl)ethyl)quinoxalin-6-amine
Show/Hide
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C28H32N8O2
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1
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| 1 |
IC50 > 10000 nM
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CP0726447
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N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(trifluoromethoxy)phenyl)quinoxalin-6-amine hydrochloride
Show/Hide
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C23H21ClF3N5O
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1
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| 1 |
IC50 > 10000 nM
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CP0726485
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2-(4-(7-((cyclopropylmethyl)(phenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
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C23H23N5O
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1
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| 1 |
IC50 > 10000 nM
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CP0726549
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1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidin-2-one
Show/Hide
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C26H28N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0726555
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2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-methoxyethyl)acetamide
Show/Hide
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C28H32N6O4
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1
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| 1 |
IC50 > 10000 nM
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CP0735248
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N-(3,5-Dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-[3-(4-methylpyridin-2-yl)prop-2-yn-1-yl]quinoxalin-6-amine
Show/Hide
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C29H26N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0738547
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7-[N-(cyclopropylmethyl)-3,5-dimethoxy-anilino]-2-[1-[2-(dimethylsulfamoylamino)ethyl]pyrazol-4-yl]quinoxaline
Show/Hide
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C27H33N7O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0744800
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N-(2-(1H-pyrazol-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C25H25N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0748524
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N-(3,5-dimethoxyphenyl)-N-(4-(4-methoxypyrimidin-2-yl)-2-methylbut-3-yn-2-yl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C30H29N7O3
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1
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| 1 |
IC50 > 10000 nM
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CP0748526
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-(trifluoromethyl)pyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
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C29H23F3N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0749392
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N-(2-(1H-tetrazol-5-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C23H23N9O2
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1
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| 1 |
IC50 > 10000 nM
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CP0751761
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tert-butyl 4-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Show/Hide
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C31H38N6O5
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1
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| 1 |
IC50 > 10000 nM
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CP0751768
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N1-(cyclopropylmethyl)-N3,N3-dimethyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)benzene-1,3-diamine hydrochloride
Show/Hide
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C24H27ClN6
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1
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| 1 |
IC50 > 10000 nM
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CP0751770
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3-(1-(2-aminoethyl)-1H-pyrazol-4-yl)-N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)quinoxalin-6-amine
Show/Hide
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C25H28N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0757780
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4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)benzonitrile
Show/Hide
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C30H24N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0758214
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(S)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-yl acetate
Show/Hide
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C25H24F3N5O4
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1
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| 1 |
IC50 > 10000 nM
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CP0762383
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N1-(3,5-dimethoxyphenyl)-N2-isopropyl-3-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)butane-1,2-diamine hydrochloride
Show/Hide
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C28H37ClN6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0767025
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N-(2-aminoethyl)-2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)acetamide hydrochloride
Show/Hide
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C24H28ClN7O3
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1
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| 1 |
IC50 > 10000 nM
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CP0773259
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N-(3,5-dimethoxyphenyl)-N-(3-(6-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C29H26N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0773301
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N-(3,5-dimethoxyphenyl)-N-((1-(4-methoxypyrimidin-2-yl)piperidin-4-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C31H34N8O3
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1
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| 1 |
IC50 > 10000 nM
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CP0776290
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N-(cyclopropylmethyl)-N-(3-fluoro-5-methoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C22H20FN5O
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1
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| 1 |
IC50 > 10000 nM
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CP0786937
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N-(cyclopentylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C26H29N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0803485
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N-(3-((diethylamino)methyl)-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
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C31H41N7O
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1
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| 1 |
IC50 > 10000 nM
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CP0806540
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N-(2-(4H-1,2,4-triazol-4-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C24H24N8O2
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1
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| 1 |
IC50 > 10000 nM
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CP0809003
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N-(3-(2-bromopyridin-3-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H23BrN6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0811738
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N-(3,5-dimethoxyphenyl)-N-(3-(1-methyl-1H-imidazol-5-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C27H25N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0837741
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N-(cyclopropylmethyl)-N-(3-methoxy-5-(2-(methylamino)ethoxy)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C26H30N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0850936
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(2-methoxyethyl)acetamide
Show/Hide
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C25H28N6O4
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1
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| 1 |
IC50 > 10000 nM
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CP0851333
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4-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)piperidin-4-ol
Show/Hide
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C26H30N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0851636
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2-(4-(7-((3-(2-hydroxyethoxy)-5-methoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
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C24H27N5O5
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1
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| 1 |
IC50 > 10000 nM
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CP0864427
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3-((3-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-hydroxypropyl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
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C25H28N6O4
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1
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| 1 |
IC50 > 10000 nM
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CP0873125
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2-(4-(7-((2-aminoethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol hydrochloride
Show/Hide
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C23H27ClN6O3
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0494148
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1-[4-[3-[4-amino-5-(3-hydroxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
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C22H26N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0570250
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1-[4-[3-[4-amino-5-(2-hydroxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
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|
C22H26N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0576190
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1-[4-[3-[4-amino-5-(4-chloro-3-methoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
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|
C23H27ClN6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0166373
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3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(isoquinolin-5-yl)-4-methylbenzamide
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C28H22N8O
|
1
|
| 1 |
IC50 = 10577 nM
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|
|
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CP0388616
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3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxy-6-phenylpyrazolo[1,5-a]pyrimidin-7-amine
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C26H29N5O3
|
1
|
| 1 |
IC50 > 11000 nM
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|
|
