General Information of the Compound
| Compound ID |
CP0751761
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| Compound Name |
tert-butyl 4-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
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| Structure |
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| Formula |
C31H38N6O5
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| Molecular Weight |
574.682
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| Canonical SMILES |
COc1cc(OC)cc(N(CCO)c2ccc3ncc(-c4cnn(C5CCN(C(=O)OC(C)(C)C)CC5)c4)nc3c2)c1
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| InChI |
InChI=1S/C31H38N6O5/c1-31(2,3)42-30(39)35-10-8-22(9-11-35)37-20-21(18-33-37)29-19-32-27-7-6-23(16-28(27)34-29)36(12-13-38)24-14-25(40-4)17-26(15-24)41-5/h6-7,14-20,22,38H,8-13H2,1-5H3
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| InChIKey |
SRQIALHPCHADMP-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2