Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(5-tert-butyl-1,2-oxazol-3-yl)-5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
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 PubChem ID
CID: 59394335
Canonical SMILES
CC(C)(C)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)no1
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Compound Formula C22H22N6O3
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  3
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
2
IC50 = 59 nM
   TI
   LI
   LO
   TS
3
IC50 = 59.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9 nM