General Information of the Compound
| Compound ID |
CP0701263
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| Compound Name |
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-((4-methoxypiperidin-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
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| Structure |
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| Formula |
C30H36N6O3
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| Molecular Weight |
528.657
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| Canonical SMILES |
COc1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(CC5(OC)CCNCC5)c4)nc3c2)c1
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| InChI |
InChI=1S/C30H36N6O3/c1-37-25-12-24(13-26(15-25)38-2)36(18-21-4-5-21)23-6-7-27-28(14-23)34-29(17-32-27)22-16-33-35(19-22)20-30(39-3)8-10-31-11-9-30/h6-7,12-17,19,21,31H,4-5,8-11,18,20H2,1-3H3
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| InChIKey |
IJNFMKJSNQLEOT-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2