Brief Information of the Compound and Protein
Compound Name
N1-(3,5-dimethoxyphenyl)-N1-(3-(5-ethyl-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-isopropylethane-1,2-diamine hydrochloride
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PubChem ID
CID: 134139651
Canonical SMILES
CCc1c(-c2cnc3ccc(N(CCNC(C)C)c4cc(OC)cc(OC)c4)cc3n2)cnn1C.Cl
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Compound Formula C27H35ClN6O2
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 1778.28 nM
   TI
   LI
   LO
   TS
2
IC50 = 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 1000 nM