General Information of the Compound
| Compound ID |
CP0692228
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| Compound Name |
N1-(3-ethoxy-5-fluorophenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
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| Structure |
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| Formula |
C22H23FN6O
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| Molecular Weight |
406.465
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| Canonical SMILES |
CCOc1cc(F)cc(N(CCN)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1
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| InChI |
InChI=1S/C22H23FN6O/c1-3-30-19-9-16(23)8-18(10-19)29(7-6-24)17-4-5-20-21(11-17)27-22(13-25-20)15-12-26-28(2)14-15/h4-5,8-14H,3,6-7,24H2,1-2H3
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| InChIKey |
NPQVZUPDGURAIA-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2