General Information of the Compound
| Compound ID |
CP0160345
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| Compound Name |
2-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenyl]-N-(1-propan-2-ylpyrazol-4-yl)acetamide
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| Structure |
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| Formula |
C24H26N6O3
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| Molecular Weight |
446.511
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| Canonical SMILES |
COc1cc2ncnc(Nc3ccc(CC(=O)Nc4cnn(c4)C(C)C)cc3)c2cc1OC
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| InChI |
InChI=1S/C24H26N6O3/c1-15(2)30-13-18(12-27-30)28-23(31)9-16-5-7-17(8-6-16)29-24-19-10-21(32-3)22(33-4)11-20(19)25-14-26-24/h5-8,10-15H,9H2,1-4H3,(H,28,31)(H,25,26,29)
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| InChIKey |
FQGHYVHLTQUXGX-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00888, Mast/stem cell growth factor receptor Kit
Protein ID: PT00864, Vascular endothelial growth factor receptor 2