General Information of the Compound
| Compound ID |
CP0223528
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| Compound Name |
5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)-N-[3-(trifluoromethyl)phenyl]indole-1-carboxamide
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| Structure |
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| Formula |
C23H18F3N5O2
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| Molecular Weight |
453.424
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| Canonical SMILES |
FC(F)(F)c1cccc(NC(=O)n2ccc3cc(Oc4ncnc5CNCCc45)ccc23)c1
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| InChI |
InChI=1S/C23H18F3N5O2/c24-23(25,26)15-2-1-3-16(11-15)30-22(32)31-9-7-14-10-17(4-5-20(14)31)33-21-18-6-8-27-12-19(18)28-13-29-21/h1-5,7,9-11,13,27H,6,8,12H2,(H,30,32)
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| InChIKey |
FKMYXQCCIDUXCG-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound