Brief Information of the Compound and Protein
Compound Name
methyl 2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)pyrimidine-4-carboxylate
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PubChem ID
CID: 68209205
Canonical SMILES
COC(=O)c1ccnc(C#CCN(c2cc(OC)cc(OC)c2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)n1
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Compound Formula C29H25N7O4
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 5888.44 nM
   TI
   LI
   LO
   TS
2
IC50 = 6456.54 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 380.19 nM