General Information of the Compound
| Compound ID |
CP0673329
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| Compound Name |
N-(3,5-dimethoxyphenyl)-N-((2-methylthiazol-4-yl)methyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
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| Structure |
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| Formula |
C24H22N6O2S
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| Molecular Weight |
458.547
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| Canonical SMILES |
COc1cc(OC)cc(N(Cc2csc(C)n2)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1
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| InChI |
InChI=1S/C24H22N6O2S/c1-15-28-17(14-33-15)13-30(19-6-20(31-2)9-21(7-19)32-3)18-4-5-22-23(8-18)29-24(12-25-22)16-10-26-27-11-16/h4-12,14H,13H2,1-3H3,(H,26,27)
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| InChIKey |
GHEIOFQIMGYHML-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2