General Information of the Compound
| Compound ID |
CP0870207
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| Compound Name |
N-(4-methyl-5-(3-(pyridin-3-yl)-1H-indazol-6-yl)thiazol-2-yl)-2-(4-methylpiperazin-1-yl)acetamide
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| Formula |
C23H25N7OS
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| Molecular Weight |
447.568
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| Canonical SMILES |
Cc1nc(NC(=O)CN2CCN(C)CC2)sc1-c1ccc2c(-c3cccnc3)n[nH]c2c1
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| InChI |
InChI=1S/C23H25N7OS/c1-15-22(32-23(25-15)26-20(31)14-30-10-8-29(2)9-11-30)16-5-6-18-19(12-16)27-28-21(18)17-4-3-7-24-13-17/h3-7,12-13H,8-11,14H2,1-2H3,(H,27,28)(H,25,26,31)
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| InChIKey |
SQGJDOUFIABRAQ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT00864, Vascular endothelial growth factor receptor 2