Brief Information of the Compound and Protein
Compound Name
N-(4-methyl-5-(3-(pyridin-3-yl)-1H-indazol-6-yl)thiazol-2-yl)-2-(4-methylpiperazin-1-yl)acetamide
    Show/Hide
Canonical SMILES
Cc1nc(NC(=O)CN2CCN(C)CC2)sc1-c1ccc2c(-c3cccnc3)n[nH]c2c1
    Show/Hide
Compound Formula C23H25N7OS
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 251 nM
   TI
   LI
   LO
   TS