General Information of the Compound
| Compound ID |
CP0719594
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| Compound Name |
4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-N,N-dimethyl-1H-pyrazole-1-sulfonamide
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| Structure |
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| Formula |
C25H28N6O4S
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| Molecular Weight |
508.604
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| Canonical SMILES |
COc1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(S(=O)(=O)N(C)C)c4)nc3c2)c1
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| InChI |
InChI=1S/C25H28N6O4S/c1-29(2)36(32,33)31-16-18(13-27-31)25-14-26-23-8-7-19(11-24(23)28-25)30(15-17-5-6-17)20-9-21(34-3)12-22(10-20)35-4/h7-14,16-17H,5-6,15H2,1-4H3
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| InChIKey |
UTNUSBXULLEVQT-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2