Brief Information of the Compound and Protein
Compound Name
1-[4-(3-amino-1H-pyrazol-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea
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PubChem ID
CID: 127045071
Canonical SMILES
CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cc(N)n[nH]2)no1
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Compound Formula C17H20N6O2
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 1520 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 610 nM