General Information of the Compound
| Compound ID |
CP0664784
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| Compound Name |
3-((cyclopropylmethyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-fluoro-N-methylbenzamide
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| Structure |
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| Formula |
C26H27FN6O
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| Molecular Weight |
458.541
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| Canonical SMILES |
CNC(=O)c1cc(F)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C(C)C)c4)nc3c2)c1
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| InChI |
InChI=1S/C26H27FN6O/c1-16(2)33-15-19(12-30-33)25-13-29-23-7-6-21(11-24(23)31-25)32(14-17-4-5-17)22-9-18(26(34)28-3)8-20(27)10-22/h6-13,15-17H,4-5,14H2,1-3H3,(H,28,34)
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| InChIKey |
RZQBKZYEBJUPTF-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2