Brief Information of the Compound and Protein
Compound Name
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-((trimethylsilyl)methyl)ethane-1,2-diamine hydrochloride
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PubChem ID
CID: 54591360
SID: 131341161
Canonical SMILES
COc1cc(OC)cc(N(CCNC[Si](C)(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1.Cl
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Compound Formula C26H35ClN6O2Si
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
2
IC50 = 9120.11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 63.1 nM