General Information of the Compound
| Compound ID |
CP0672897
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| Compound Name |
N-(cyclopropylmethyl)-N-(3-methoxy-5-(trifluoromethyl)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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| Structure |
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| Formula |
C24H22F3N5O
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| Molecular Weight |
453.468
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| Canonical SMILES |
COc1cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)cc(C(F)(F)F)c1
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| InChI |
InChI=1S/C24H22F3N5O/c1-31-14-16(11-29-31)23-12-28-21-6-5-18(10-22(21)30-23)32(13-15-3-4-15)19-7-17(24(25,26)27)8-20(9-19)33-2/h5-12,14-15H,3-4,13H2,1-2H3
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| InChIKey |
HJXFZYAQOJRGRY-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2