General Information of the Compound
| Compound ID |
CP0704634
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| Compound Name |
2-(3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(cyclopropylmethyl)amino)-5-methoxyphenoxy)ethanol
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| Structure |
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| Formula |
C24H25N5O3
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| Molecular Weight |
431.496
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| Canonical SMILES |
COc1cc(OCCO)cc(N(CC2CC2)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1
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| InChI |
InChI=1S/C24H25N5O3/c1-31-20-8-19(9-21(11-20)32-7-6-30)29(15-16-2-3-16)18-4-5-22-23(10-18)28-24(14-25-22)17-12-26-27-13-17/h4-5,8-14,16,30H,2-3,6-7,15H2,1H3,(H,26,27)
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| InChIKey |
BXBWZDDZLDSYQH-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2