General Information of the Compound
| Compound ID |
CP0720055
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| Compound Name |
2-(4-(3-((2-aminoethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-6-yl)-1H-pyrazol-1-yl)-N-methylacetamide
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| Structure |
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| Formula |
C24H27N7O3
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| Molecular Weight |
461.526
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| Canonical SMILES |
CNC(=O)Cn1cc(-c2ccc3ncc(N(CCN)c4cc(OC)cc(OC)c4)nc3c2)cn1
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| InChI |
InChI=1S/C24H27N7O3/c1-26-24(32)15-30-14-17(12-28-30)16-4-5-21-22(8-16)29-23(13-27-21)31(7-6-25)18-9-19(33-2)11-20(10-18)34-3/h4-5,8-14H,6-7,15,25H2,1-3H3,(H,26,32)
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| InChIKey |
JQYPWJCACYTKIC-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2