General Information of the Compound
| Compound ID |
CP0851636
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| Compound Name |
2-(4-(7-((3-(2-hydroxyethoxy)-5-methoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
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| Structure |
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| Formula |
C24H27N5O5
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| Molecular Weight |
465.51
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| Canonical SMILES |
COc1cc(OCCO)cc(N(CCO)c2ccc3ncc(-c4cnn(CCO)c4)nc3c2)c1
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| InChI |
InChI=1S/C24H27N5O5/c1-33-20-10-19(11-21(13-20)34-9-8-32)29(5-7-31)18-2-3-22-23(12-18)27-24(15-25-22)17-14-26-28(16-17)4-6-30/h2-3,10-16,30-32H,4-9H2,1H3
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| InChIKey |
ZNCQPSDLZARYKS-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2