General Information of the Compound
| Compound ID |
CP0831841
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| Compound Name |
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-fluoroethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
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| Structure |
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| Formula |
C25H26FN5O2
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| Molecular Weight |
447.514
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| Canonical SMILES |
COc1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(CCF)c4)nc3c2)c1
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| InChI |
InChI=1S/C25H26FN5O2/c1-32-21-9-20(10-22(12-21)33-2)31(15-17-3-4-17)19-5-6-23-24(11-19)29-25(14-27-23)18-13-28-30(16-18)8-7-26/h5-6,9-14,16-17H,3-4,7-8,15H2,1-2H3
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| InChIKey |
SEVOZKSFLJRZMK-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2