General Information of the Compound
Compound ID |
CP0688449
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Compound Name |
N-(3,5-dimethoxyphenyl)-N-(dimethylsulfamoyl)-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine
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Structure |
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Formula |
C22H24N6O4S
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Molecular Weight |
468.539
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Canonical SMILES |
COc1cc(OC)cc(N(c2ccc3ncc(-c4cnn(C)c4)nc3c2)S(=O)(=O)N(C)C)c1
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InChI |
InChI=1S/C22H24N6O4S/c1-26(2)33(29,30)28(17-8-18(31-4)11-19(9-17)32-5)16-6-7-20-21(10-16)25-22(13-23-20)15-12-24-27(3)14-15/h6-14H,1-5H3
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InChIKey |
YFVSIFXYGYSXNP-UHFFFAOYSA-N
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Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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ChEMBL ID |
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2