Brief Information of the Compound and Protein
Compound Name
N1-(cyclopropylmethyl)-N3-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)benzene-1,3-diamine
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PubChem ID
CID: 68208796
Canonical SMILES
CNc1cccc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1
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Compound Formula C23H24N6
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 676.08 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 398.11 nM