General Information of the Compound
| Compound ID |
CP0749415
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| Compound Name |
2-(3-((2-aminoethyl)(7-(1-methyl-1H-pyrazol-4-yl)quinoxalin-2-yl)amino)-5-fluorophenoxy)ethanol
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| Structure |
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| Formula |
C22H23FN6O2
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| Molecular Weight |
422.464
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| Canonical SMILES |
Cn1cc(-c2ccc3ncc(N(CCN)c4cc(F)cc(OCCO)c4)nc3c2)cn1
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| InChI |
InChI=1S/C22H23FN6O2/c1-28-14-16(12-26-28)15-2-3-20-21(8-15)27-22(13-25-20)29(5-4-24)18-9-17(23)10-19(11-18)31-7-6-30/h2-3,8-14,30H,4-7,24H2,1H3
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| InChIKey |
HIMWRONMJKQVOO-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2