Brief Information of the Compound and Protein
Compound Name
2-(3-((2-aminoethyl)(7-(1-methyl-1H-pyrazol-4-yl)quinoxalin-2-yl)amino)-5-fluorophenoxy)ethanol
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PubChem ID
CID: 89447236
Canonical SMILES
Cn1cc(-c2ccc3ncc(N(CCN)c4cc(F)cc(OCCO)c4)nc3c2)cn1
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Compound Formula C22H23FN6O2
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 5754.4 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 66.07 nM