General Information of the Compound
| Compound ID |
CP0064283
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| Compound Name |
Balversa
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| Synonyms |
1,2-Ethanediamine, N1-(3,5-dimethoxyphenyl)-N2-(1-methylethyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl)-
1346242-81-6
890E37NHMV
AC-30222
AKOS030526429
AS-35040
CHEMBL3545376
CS-4988
D10927
DB12147
Erdafitinib
Erdafitinib (USAN/INN)
Erdafitinib [USAN:INN]
GTPL9039
HY-18708
JNJ-42756493 (Erdafitinib)
KB-333716
MolPort-044-560-398
N'-(3,5-dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quino
SCHEMBL2583760
UNII-890E37NHMV
ZINC168520308
compound 4 [WO2011135376]
s8401
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| Structure |
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| Formula |
C25H30N6O2
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| Molecular Weight |
446.555
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| Canonical SMILES |
COc1cc(OC)cc(c1)N(CCNC(C)C)c1ccc2ncc(nc2c1)-c1cnn(C)c1
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| InChI |
InChI=1S/C25H30N6O2/c1-17(2)26-8-9-31(20-10-21(32-4)13-22(11-20)33-5)19-6-7-23-24(12-19)29-25(15-27-23)18-14-28-30(3)16-18/h6-7,10-17,26H,8-9H2,1-5H3
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| InChIKey |
OLAHOMJCDNXHFI-UHFFFAOYSA-N
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| CAS |
1346242-81-6
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2
Clinical Information about the Compound