Brief Information of the Compound and Protein
Compound Name
3-[[7-[3-(1,1-dioxo-1,4-thiazinan-4-yl)propoxy]-6-methoxyquinazolin-4-yl]amino]-4-fluoro-2-methylphenol
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PubChem ID
CID: 127046310
Canonical SMILES
COc1cc2c(Nc3c(F)ccc(O)c3C)ncnc2cc1OCCCN1CCS(=O)(=O)CC1
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Compound Formula C23H27FN4O5S
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS