General Information of the Compound
| Compound ID |
CP0898526
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| Compound Name |
(E)-N-(4-methyl-5-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thiazol-2-yl)acetamide
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| Formula |
C20H17N5OS
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| Molecular Weight |
375.457
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| Canonical SMILES |
CC(=O)Nc1nc(C)c(-c2ccc3c(/C=C/c4ccccn4)n[nH]c3c2)s1
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| InChI |
InChI=1S/C20H17N5OS/c1-12-19(27-20(22-12)23-13(2)26)14-6-8-16-17(24-25-18(16)11-14)9-7-15-5-3-4-10-21-15/h3-11H,1-2H3,(H,24,25)(H,22,23,26)/b9-7+
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| InChIKey |
DCHAMIDLDHJNCN-VQHVLOKHSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT00864, Vascular endothelial growth factor receptor 2