Brief Information of the Compound and Protein
Compound Name
5-[(6-acetyl-5,7-dihydropyrrolo[3,4-d]pyrimidin-4-yl)oxy]-N-(5-cyclopropyl-1,2-oxazol-3-yl)indole-1-carboxamide
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PubChem ID
CID: 59394015
Canonical SMILES
CC(=O)N1Cc2ncnc(Oc3ccc4n(ccc4c3)C(=O)Nc3cc(on3)C3CC3)c2C1
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Compound Formula C23H20N6O4
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 10.1 nM
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