Brief Information of the Compound and Protein
Compound Name
1-[4-[3-[4-amino-5-(4-chloro-3-methoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
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Canonical SMILES
COc1cc(ccc1Cl)-c1cn([C@@H]2C[C@@H](C2)N2CCN(CC2)C(C)=O)c2ncnc(N)c12
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Compound Formula C23H27ClN6O2
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS