General Information of the Compound
| Compound ID |
CP0692285
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| Compound Name |
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(4-hydroxypyridin-2-yl)acetamide
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| Structure |
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| Formula |
C27H25N7O4
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| Molecular Weight |
511.542
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| Canonical SMILES |
COc1cc(OC)cc(N(CC(=O)Nc2cc(O)ccn2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1
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| InChI |
InChI=1S/C27H25N7O4/c1-33-15-17(13-30-33)25-14-29-23-5-4-18(10-24(23)31-25)34(19-8-21(37-2)12-22(9-19)38-3)16-27(36)32-26-11-20(35)6-7-28-26/h4-15H,16H2,1-3H3,(H2,28,32,35,36)
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| InChIKey |
JMBVTEKOAZJGIC-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2