Brief Information of the Compound and Protein
Compound Name
4-fluoro-3-[[6-methoxy-7-[3-[2-(trifluoromethyl)pyrrolidin-1-yl]propoxy]quinazolin-4-yl]amino]-2-methylphenol
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PubChem ID
CID: 118112202
Canonical SMILES
COc1cc2c(Nc3c(F)ccc(O)c3C)ncnc2cc1OCCCN1CCCC1C(F)(F)F
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Compound Formula C24H26F4N4O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS