Brief Information of the Compound and Protein
Compound Name
4-(4-Bromo-2-fluoroanilino)-6,7-dimethoxyquinazoline
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PubChem ID
CID: 21701562
SID: 104166512
Canonical SMILES
COc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1OC
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Compound Formula C16H13BrFN3O2
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 460 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1650 nM