Brief Information of the Compound and Protein
Compound Name
4-(4-Methyl-piperazin-1-ylmethyl)-N-{4-methyl-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-thiazol-2-yl}-3-trifluoromethyl-benzamide
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Canonical SMILES
Cc1nc(NC(=O)c2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)sc1Sc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1
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Compound Formula C32H30F3N7OS2
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 376 nM
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