Brief Information of the Compound and Protein
Compound Name
5-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]indole-1-carboxamide
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PubChem ID
CID: 59394176
Canonical SMILES
FC(F)(F)C1(CC1)c1cc(NC(=O)n2ccc3cc(Oc4ncnc5CNCc45)ccc23)no1
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Compound Formula C22H17F3N6O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 5 nM
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   LI
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