General Information of the Compound
| Compound ID |
CP0692273
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| Compound Name |
3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3-hydroxypropyl)amino)-5-methoxyphenol
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| Structure |
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| Formula |
C21H21N5O3
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| Molecular Weight |
391.431
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| Canonical SMILES |
COc1cc(O)cc(N(CCCO)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1
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| InChI |
InChI=1S/C21H21N5O3/c1-29-18-8-16(7-17(28)10-18)26(5-2-6-27)15-3-4-19-20(9-15)25-21(13-22-19)14-11-23-24-12-14/h3-4,7-13,27-28H,2,5-6H2,1H3,(H,23,24)
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| InChIKey |
PRQYUAHLKCIUTM-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2