General Information of the Compound
| Compound ID |
CP0667776
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| Compound Name |
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-methoxyethyl)-2-methylpropanamide
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| Structure |
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| Formula |
C30H36N6O4
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| Molecular Weight |
544.656
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| Canonical SMILES |
COCCNC(=O)C(C)(C)n1cc(-c2cnc3ccc(N(CC4CC4)c4cc(OC)cc(OC)c4)cc3n2)cn1
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| InChI |
InChI=1S/C30H36N6O4/c1-30(2,29(37)31-10-11-38-3)36-19-21(16-33-36)28-17-32-26-9-8-22(14-27(26)34-28)35(18-20-6-7-20)23-12-24(39-4)15-25(13-23)40-5/h8-9,12-17,19-20H,6-7,10-11,18H2,1-5H3,(H,31,37)
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| InChIKey |
NGLRSTVZLVHSJO-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT00864, Vascular endothelial growth factor receptor 2