General Information of the Compound
| Compound ID |
CP0893381
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| Compound Name |
2-(5-(6,7-dimethoxyquinolin-4-yloxy)-3-methoxypyridin-2-yl)-N-(1-isopropyl-1H-pyrazol-4-yl)acetamide
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| Structure |
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| Formula |
C25H27N5O5
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| Molecular Weight |
477.521
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| Canonical SMILES |
COc1cc2nccc(Oc3cnc(CC(=O)Nc4cnn(C(C)C)c4)c(OC)c3)c2cc1OC
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| InChI |
InChI=1S/C25H27N5O5/c1-15(2)30-14-16(12-28-30)29-25(31)11-20-22(32-3)8-17(13-27-20)35-21-6-7-26-19-10-24(34-5)23(33-4)9-18(19)21/h6-10,12-15H,11H2,1-5H3,(H,29,31)
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| InChIKey |
RWOUESXTVRIRCN-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00888, Mast/stem cell growth factor receptor Kit
Protein ID: PT00864, Vascular endothelial growth factor receptor 2