Brief Information of the Compound and Protein
Compound Name
N-(5-tert-butyl-1,2-oxazol-3-yl)-7-(6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-yloxy)imidazo[1,2-a]pyridine-3-carboxamide
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PubChem ID
CID: 127045353
Canonical SMILES
CC(C)(C)c1cc(NC(=O)c2cnc3cc(Oc4ncnc5CNCc45)ccn23)no1
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Compound Formula C21H21N7O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 78 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 90 nM