| Compound ID |
Compound Name |
Compound Formula |
|
CP0410248
|
(2S,3S,4R,5R)-5-(6-amino-2-fluoropurin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C12H15FN6O4
|
1
|
| 1 |
EC50 = 2.3 nM
|
|
|
|
CP0432015
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-oxo-2-(phenylamino)ethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H27N7O6
|
1
|
| 1 |
EC50 = 7.3 nM
|
|
|
|
CP0309505
|
2-((1H-imidazol-2-yl)methylthio)-6-amino-4-(4-methoxyphenyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C18H14N6OS
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0514926
|
2-amino-4-[4-(cyclopropylmethoxy)phenyl]-6-(1H-imidazol-2-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C21H18N6OS
|
1
|
| 1 |
EC50 = 9.5 nM
|
|
|
|
CP0106489
|
2-Amino-4-(3-hydroxy-phenyl)-6-(1H-imidazol-2-ylmethylsulfanyl)-pyridine-3,5-dicarbonitrile
Show/Hide
|
C17H12N6OS
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0405562
|
(2S,3S,4R,5R)-5-(6-(4-(2-(4-bromophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H26BrN7O6
|
1
|
| 1 |
EC50 = 10.5 nM
|
|
|
|
CP0405220
|
2-amino-4-(4-ethoxyphenyl)-6-(1H-imidazol-2-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C19H16N6OS
|
1
|
| 1 |
EC50 = 11.7 nM
|
|
|
|
CP0106488
|
2-Amino-4-(4-hydroxy-phenyl)-6-(1H-imidazol-2-ylmethylsulfanyl)-pyridine-3,5-dicarbonitrile
Show/Hide
|
C17H12N6OS
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0373609
|
(2S,3S,4R,5R)-5-(6-(4-(2-(4-chlorophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H26ClN7O6
|
1
|
| 1 |
EC50 = 12.3 nM
|
|
|
|
CP0429454
|
3-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylmethyl]benzamide
Show/Hide
|
C25H21N5O2S
|
1
|
| 1 |
EC50 = 12.7 nM
|
|
|
|
CP0436335
|
(2S,3S,4R,5R)-5-[6-(2,2-diphenylethylamino)-2-fluoropurin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C26H27FN6O4
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0457727
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(4-(2-(4-fluorophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H26FN7O6
|
1
|
| 1 |
EC50 = 15.2 nM
|
|
|
|
CP0457726
|
(2S,3S,4R,5R)-5-(6-(4-(2-(4-tert-butylphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C30H35N7O6
|
1
|
| 1 |
EC50 = 16.4 nM
|
|
|
|
CP0137011
|
2-((1H-imidazol-2-yl)methylthio)-6-amino-4-phenylpyridine-3,5-dicarbonitrile
Show/Hide
|
C17H12N6S
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0373608
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-(4-iodophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H26IN7O6
|
1
|
| 1 |
EC50 = 30.2 nM
|
|
|
|
CP0343792
|
2-[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylacetamide
Show/Hide
|
C19H17N5O2S
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0373607
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-oxo-2-(pyridin-4-ylamino)ethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide
Show/Hide
|
C25H26N8O6
|
1
|
| 1 |
EC50 = 32.3 nM
|
|
|
|
CP0407994
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-(4-methoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide
Show/Hide
|
C27H29N7O7
|
1
|
| 1 |
EC50 = 32.4 nM
|
|
|
|
CP0444120
|
2-Amino-6-(1H-imidazol-2-ylmethylsulfanyl)-4-(3-methoxy-phenyl)-pyridine-3,5-dicarbonitrile
Show/Hide
|
C18H14N6OS
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0412531
|
(2S,3S,4R,5R)-5-(6-(4-(2-(benzo[d][1,3]dioxol-5-ylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C27H27N7O8
|
1
|
| 1 |
EC50 = 35.5 nM
|
|
|
|
CP0039348
|
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C12H16N6O4
|
11
|
| 1 |
EC50 = 38 nM
|
|
|
| 2 |
EC50 = 104 nM
|
|
|
| 3 |
EC50 = 155 nM
|
|
|
| 4 |
EC50 = 160 nM
|
|
|
| 5 |
EC50 = 440 nM
|
|
|
| 6 |
EC50 = 1510 nM
|
|
|
| 7 |
EC50 = 2400 nM
|
|
|
| 8 |
EC50 = 3630.78 nM
|
|
|
| 9 |
EC50 > 10000 nM
|
|
|
| 10 |
Ki = 1270 nM
|
|
|
| 11 |
Ki = 1890 nM
|
|
|
|
CP0476084
|
2-[6-amino-3,5-dicyano-4-(4-ethoxyphenyl)pyridin-2-yl]sulfanylacetamide
Show/Hide
|
C17H15N5O2S
|
1
|
| 1 |
EC50 = 38 nM
|
|
|
|
CP0421958
|
(2S,3S,4R,5R)-5-(2-chloro-6-(4-(2-oxo-2-(phenylamino)ethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H26ClN7O6
|
1
|
| 1 |
EC50 = 42.6 nM
|
|
|
|
CP0408013
|
(2S,3S,4R,5R)-5-(6-(4-(2-(3,4-dimethoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C28H31N7O8
|
1
|
| 1 |
EC50 = 45.4 nM
|
|
|
|
CP0057366
|
(2R,3R,4S,5R)-2-(6-amino-2-((S)-1-hydroxy-3-phenylpropan-2-ylamino)-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydrofuran-3,4-diol
Show/Hide
|
C21H26N10O4
|
2
|
| 1 |
EC50 = 51 nM
|
|
|
| 2 |
EC50 = 1000 nM
|
|
|
|
CP0429452
|
2-amino-4-[4-(cyclopropylmethoxy)phenyl]-6-(1H-1,2,4-triazol-5-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C20H17N7OS
|
1
|
| 1 |
EC50 = 51 nM
|
|
|
|
CP0454289
|
(2S,3S,4R,5R)-5-(6-(4-(2-(3,5-dimethoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C28H31N7O8
|
1
|
| 1 |
EC50 = 53.6 nM
|
|
|
|
CP0425048
|
(2S,3S,4R,5R)-N-ethyl-5-(6-guanidino-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C13H18N8O4
|
1
|
| 1 |
EC50 = 54.5 nM
|
|
|
|
CP0442429
|
1-deoxy-1-{6-[N'-(furan-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C17H19N7O6
|
1
|
| 1 |
EC50 = 82 nM
|
|
|
|
CP0469491
|
2-amino-4-[4-(cyclopropylmethoxy)phenyl]-6-(1H-pyrazol-5-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C21H18N6OS
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0469492
|
2-[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanyl-N-methylacetamide
Show/Hide
|
C20H19N5O2S
|
1
|
| 1 |
EC50 = 94 nM
|
|
|
|
CP0493012
|
1-deoxy-1-[6-{4-[(2-trifluoromethyl-phenylcarbamoyl)-methoxy]-phenylamino}-9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C27H26F3N7O6
|
1
|
| 1 |
EC50 = 107 nM
|
|
|
|
CP0410251
|
(2S,3S,4R,5R)-5-[6-(2,2-diphenylethylamino)-2-fluoropurin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
Show/Hide
|
C25H25FN6O4
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0433027
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-(4-aminophenyl)ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C20H26N8O4
|
1
|
| 1 |
EC50 = 126 nM
|
|
|
|
CP0469490
|
2-amino-4-[4-(cyclopropylmethoxy)phenyl]-6-(1H-imidazol-5-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C21H18N6OS
|
1
|
| 1 |
EC50 = 139 nM
|
|
|
|
CP0433025
|
(2S,3S,4R,5R)-5-[6-amino-2-(2-phenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C20H25N7O4
|
1
|
| 1 |
EC50 = 145 nM
|
|
|
|
CP0412406
|
(2S,3S,4R,5R)-5-(6-(4-(2-(benzylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C27H29N7O6
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0529145
|
2-[4-(4-acetamidophenyl)-6-amino-3,5-dicyanopyridin-2-yl]sulfanylacetamide
Show/Hide
|
C17H14N6O2S
|
1
|
| 1 |
EC50 = 164 nM
|
|
|
|
CP0467106
|
1-deoxy-1-{2-chloro-6-[N'-(5-methyl-thiophene-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C18H20ClN7O5S
|
1
|
| 1 |
EC50 = 175 nM
|
|
|
|
CP0394486
|
(2S,3S,4R,5R)-5-(6-(4-(2-(benzylamino)-2-oxoethoxy)phenylamino)-2-chloro-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C27H28ClN7O6
|
1
|
| 1 |
EC50 = 175 nM
|
|
|
|
CP0511765
|
2-[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanyl-N-(hydroxymethyl)acetamide
Show/Hide
|
C20H19N5O3S
|
1
|
| 1 |
EC50 = 182 nM
|
|
|
|
CP0435735
|
1-deoxy-1-{2-chloro-6-[N'-(thiophene-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C17H18ClN7O5S
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0428091
|
1-deoxy-1-{2-chloro-6-[N'-(furan-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C17H18ClN7O6
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0469489
|
2-[6-amino-3,5-dicyano-4-(4-ethoxyphenyl)pyridin-2-yl]sulfanyl-N-methylacetamide
Show/Hide
|
C18H17N5O2S
|
1
|
| 1 |
EC50 = 211 nM
|
|
|
|
CP0394483
|
(2R,3R,4S,5R)-2-(6-amino-2-(2-(6-chloro-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C20H21ClN6O5
|
1
|
| 1 |
EC50 = 216 nM
|
|
|
|
CP0409677
|
(2S,3S,4R,5R)-5-(6-amino-2-((S)-3-hydroxy-3-phenylprop-1-ynyl)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C21H22N6O5
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0396254
|
(2R,3R,4S,5R)-2-[6-(cyclopropylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C15H19N9O3
|
2
|
| 1 |
EC50 = 222 nM
|
|
|
| 2 |
EC50 = 675 nM
|
|
|
|
CP0467107
|
1-deoxy-1-{6-[N'-(5-methyl-furan-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C18H21N7O6
|
1
|
| 1 |
EC50 = 227 nM
|
|
|
|
CP0234114
|
2-amino-8-(2-morpholinoethoxy)-4-phenyl-5H-indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C23H22N4O3
|
1
|
| 1 |
EC50 = 230 nM
|
|
|
|
CP0389281
|
(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-[(3-iodophenyl)methylamino]purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C19H20IN9O3
|
1
|
| 1 |
EC50 = 235 nM
|
|
|
|
CP0399503
|
(2S,3S,4R,5R)-5-(6-(4-(2-(4-methoxybenzylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C28H31N7O7
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0416329
|
(2S,3S,4R,5R)-5-[2-[2-(4-aminophenyl)ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C34H38N8O4
|
1
|
| 1 |
EC50 = 257 nM
|
|
|
|
CP0428193
|
1-deoxy-1-{6-[N'-(5-methyl-thiophene-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-Dribofuranuronamide
Show/Hide
|
C18H21N7O5S
|
1
|
| 1 |
EC50 = 273 nM
|
|
|
|
CP0491323
|
(2S,3S,4R,5R)-5-[2-[2-(4-bromophenyl)ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C34H36BrN7O4
|
1
|
| 1 |
EC50 = 296 nM
|
|
|
|
CP0425053
|
(2R,3R,4S,5R)-2-(2-(2-(1H-indol-3-yl)ethoxy)-6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C20H22N6O5
|
1
|
| 1 |
EC50 = 299 nM
|
|
|
|
CP0399501
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-(4-morpholinophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide
Show/Hide
|
C30H34N8O7
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0405561
|
(2S,3S,4R,5R)-5-(2-chloro-6-(4-(2-(cyclohexylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H32ClN7O6
|
1
|
| 1 |
EC50 = 302 nM
|
|
|
|
CP0373610
|
(2S,3S,4R,5R)-5-(6-(4-(2-(cyclohexylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H33N7O6
|
1
|
| 1 |
EC50 = 315 nM
|
|
|
|
CP0450946
|
2-amino-4-(4-ethoxyphenyl)-6-(1H-pyrazol-5-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C19H16N6OS
|
1
|
| 1 |
EC50 = 332 nM
|
|
|
|
CP0398710
|
1,3-dibutyl-9-[2-[4-[2-(diethylamino)ethoxy]phenyl]ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C30H46N6O3
|
2
|
| 1 |
EC50 = 335 nM
|
|
|
| 2 |
Ki = 109 nM
|
|
|
|
CP0435709
|
1-deoxy-1-{2-chloro-6-[N'-(3-methyl-thiophene-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C18H20ClN7O5S
|
1
|
| 1 |
EC50 = 340 nM
|
|
|
|
CP0397901
|
(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C12H15N9O3
|
1
|
| 1 |
EC50 = 347 nM
|
|
|
|
CP0469488
|
methyl 3-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylmethyl]benzoate
Show/Hide
|
C26H22N4O3S
|
1
|
| 1 |
EC50 = 347 nM
|
|
|
|
CP0416328
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-(4-bromophenyl)ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C20H24BrN7O4
|
1
|
| 1 |
EC50 = 355 nM
|
|
|
|
CP0428191
|
1-deoxy-1-{2-chloro-6-[N'-(1-H-pyrrole-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C17H19ClN8O5
|
1
|
| 1 |
EC50 = 359 nM
|
|
|
|
CP0454290
|
(2S,3S,4R,5R)-5-(2-chloro-6-(4-(2-(4-methoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C27H28ClN7O7
|
1
|
| 1 |
EC50 = 360 nM
|
|
|
|
CP0394566
|
(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-bromo-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C20H21BrN6O5
|
1
|
| 1 |
EC50 = 365 nM
|
|
|
|
CP0462353
|
1-deoxy-1-{6-[N'-(5-bromo-furan-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
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C17H18BrN7O6
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1
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| 1 |
EC50 = 369 nM
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CP0452795
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(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-(3-phenylpropoxy)phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C31H38N8O5
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1
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| 1 |
EC50 = 389 nM
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CP0408567
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(2R,3R,4S,5R)-2-[6-[(3-bromophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C19H20BrN9O3
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1
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| 1 |
EC50 = 408 nM
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CP0412407
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1-deoxy-1-{2-chloro-6-[N'-(thiophene-3-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
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C17H18ClN7O5S
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1
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| 1 |
EC50 = 450 nM
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CP0396249
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(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-(thiophen-2-ylmethylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C17H19N9O3S
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1
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| 1 |
EC50 = 527 nM
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CP0398200
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(2R,3R,4S,5R)-2-[6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C18H17ClFN9O3
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1
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| 1 |
EC50 = 530 nM
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CP0381985
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(2R,3R,4S,5R)-2-(6-amino-2-chloropurin-9-yl)-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
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C12H14ClN9O3
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1
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| 1 |
EC50 = 542 nM
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CP0391247
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(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-2-(4-bromo-phenyl)-1-hydroxymethyl-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol
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C21H25BrN10O4
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1
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| 1 |
EC50 = 560 nM
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CP0389279
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(2R,3R,4S,5R)-2-[6-[(3-chlorophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C19H20ClN9O3
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1
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| 1 |
EC50 = 592 nM
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CP0382272
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1-deoxy-1-{2-chloro-6-[N'-(2-thiophen-2-yl-acetyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
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C18H20ClN7O5S
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1
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| 1 |
EC50 = 603 nM
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CP0396248
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(2R,3R,4S,5R)-2-[6-(cyclopropylmethylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
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C16H21N9O3
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1
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| 1 |
EC50 = 637 nM
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CP0398202
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(2R,3R,4S,5R)-2-[2-chloro-6-(cyclopropylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C15H18ClN9O3
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2
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| 1 |
EC50 = 677 nM
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| 2 |
EC50 = 1150 nM
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CP0442213
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(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-(4-methoxy-phenyl)-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol
Show/Hide
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C22H28N10O5
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1
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| 1 |
EC50 = 680 nM
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CP0395216
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(2R,3R,4S,5R)-2-[6-(ethylamino)-2-[(3S)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C21H23N5O5
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1
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| 1 |
EC50 = 730 nM
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CP0410250
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[5-[(3S)-dithiolan-3-yl]pentanoylamino]phenyl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C28H38N8O5S2
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1
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| 1 |
EC50 = 739 nM
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CP0407957
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-fluoro-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H21FN6O5
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1
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| 1 |
EC50 = 767 nM
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CP0397900
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(2R,3R,4S,5R)-2-[2-chloro-6-[(2-iodophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C19H19ClIN9O3
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1
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| 1 |
EC50 = 834 nM
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CP0536354
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2-amino-4-(furan-3-yl)-6-(2-hydroxyethylsulfanyl)pyridine-3,5-dicarbonitrile
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C13H10N4O2S
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1
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| 1 |
EC50 = 852 nM
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CP0399650
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(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C30H33F3N8O5
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1
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| 1 |
EC50 = 866 nM
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CP0383018
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2-amino-6-(2-hydroxyethylsulfanyl)-4-thiophen-2-ylpyridine-3,5-dicarbonitrile
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C13H10N4OS2
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1
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| 1 |
EC50 = 885 nM
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CP0394229
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-hydroxy-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H22N6O6
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1
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| 1 |
EC50 = 896 nM
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CP0407836
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(2R,3R,4S,5R)-2-[6-amino-2-[(3S)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C19H19N5O5
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1
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| 1 |
EC50 = 920 nM
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CP0471056
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(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-[(4-chlorophenyl)methoxy]phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C29H33ClN8O5
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1
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| 1 |
EC50 = 927 nM
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CP0394224
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3S)-3-hydroxy-3-phenylprop-1-ynyl]-6-(propan-2-ylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C22H25N5O5
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1
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| 1 |
EC50 = 960 nM
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CP0383009
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methyl 3-[(6-amino-3,5-dicyano-4-thiophen-2-ylpyridin-2-yl)sulfanylmethyl]benzoate
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C20H14N4O2S2
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1
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| 1 |
EC50 = 982 nM
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CP0421266
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(2R,3S,4S,5R)-6-amino-5-ethylcarboxyamide-2-(3''-indolyl)-ethyloxy)-purin-9-yl)-tetrahydrofuran
Show/Hide
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C22H25N7O5
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1
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| 1 |
EC50 = 989 nM
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CP0397895
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(2R,3R,4S,5R)-2-[6-[[(1R,2S,4R)-2-bicyclo[2.2.1]heptanyl]amino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C19H25N9O3
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1
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| 1 |
EC50 = 1010 nM
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CP0393692
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(2S,3S,4R,5R)-5-[6-amino-2-(3-hydroxy-3-phenylprop-1-ynyl)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C21H22N6O5
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1
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| 1 |
EC50 = 1100 nM
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CP0408454
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(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-[(3-fluorophenyl)methylamino]purin-9-yl]oxolane-3,4-diol
Show/Hide
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C19H20FN9O3
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1
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| 1 |
EC50 = 1100 nM
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CP0398203
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(2R,3R,4S,5R)-2-[2-chloro-6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C18H16Cl2FN9O3
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1
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| 1 |
EC50 = 1110 nM
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CP0433028
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(2S,3S,4R,5R)-5-[6-(2,2-diphenylethylamino)-2-(2-phenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C34H37N7O4
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1
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| 1 |
EC50 = 1173 nM
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CP0432866
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(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-(4-nitro-phenyl)-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol
Show/Hide
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C21H25N11O6
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1
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| 1 |
EC50 = 1200 nM
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CP0425420
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-methoxy-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C21H24N6O6
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1
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| 1 |
EC50 = 1250 nM
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CP0404600
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(2R,3R,4S,5R)-2-[6-[(4-chloro-2-fluorophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C19H19ClFN9O3
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1
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| 1 |
EC50 = 1290 nM
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CP0391229
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(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-(4-hydroxy-phenyl)-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol
Show/Hide
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C21H26N10O5
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1
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| 1 |
EC50 = 1300 nM
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CP0398201
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(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-(oxolan-2-ylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C16H21N9O4
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1
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| 1 |
EC50 = 1340 nM
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CP0425051
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(naphthalen-2-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C22H23N5O5
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1
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| 1 |
EC50 = 1440 nM
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CP0397897
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(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-(methylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C13H17N9O3
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1
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| 1 |
EC50 = 1480 nM
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CP0410249
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[(3,5-ditert-butylbenzoyl)amino]phenyl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C35H46N8O5
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1
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| 1 |
EC50 = 1489 nM
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CP0404606
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(2R,3R,4S,5R)-2-[6-[(3-bromophenyl)methylamino]-2-chloropurin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C19H19BrClN9O3
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1
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| 1 |
EC50 = 1650 nM
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CP0058409
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-1-phenylpropan-2-ylamino)-9H-purin-9-yl)-tetrahydrofuran-3,4-diol
Show/Hide
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C19H23N5O4
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1
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| 1 |
EC50 = 1680 nM
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CP0885708
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2-[6-Ethylamino-2-(3-hydroxy-3-phenyl-prop-1-ynyl)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
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C21H23N5O5
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1
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| 1 |
EC50 = 1700 nM
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CP0432011
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(thiophen-2-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C16H19N5O5S
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1
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| 1 |
EC50 = 1780 nM
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CP0496057
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-iodo-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H21IN6O5
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1
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| 1 |
EC50 = 1870 nM
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CP0408565
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(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-(furan-2-ylmethylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C17H19N9O4
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1
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| 1 |
EC50 = 1930 nM
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CP0408566
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(2R,3R,4S,5R)-2-[2-chloro-6-(cyclopropylmethylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C16H20ClN9O3
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1
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| 1 |
EC50 = 1961 nM
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CP0871190
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2-[1-(R)-Methyl-2-(4-methoxyphenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine
Show/Hide
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C22H28N10O4
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1
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| 1 |
EC50 = 2000 nM
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CP0855184
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3-(4-(2-(6-(4-(9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-ylamino)butylamino)-6-oxohexylamino)-2-oxoethoxy)styryl)-5,5-difluoro-7-(thiophen-2-yl)-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide
Show/Hide
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C45H51BF2N10O7S
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1
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| 1 |
EC50 = 2041.74 nM
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CP0389280
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(2R,3R,4S,5R)-2-[2-chloro-6-(thiophen-2-ylmethylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C17H18ClN9O3S
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1
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| 1 |
EC50 = 2140 nM
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CP0427746
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-chloro-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H21ClN6O5
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1
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| 1 |
EC50 = 2180 nM
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CP0404609
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(2R,3R,4S,5R)-2-[2-chloro-6-[(3-fluorophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C19H19ClFN9O3
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1
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| 1 |
EC50 = 2230 nM
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CP0436338
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(2S,3S,4R,5R)-5-[2-[2-[4-[(3,5-ditert-butylbenzoyl)amino]phenyl]ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C49H58N8O5
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1
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| 1 |
EC50 = 2279 nM
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CP0437252
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(2R,3R,4S,5R)-2-[2-chloro-6-[(3-chlorophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C19H19Cl2N9O3
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1
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| 1 |
EC50 = 2390 nM
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CP0448421
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(2S,3S,4R,5R)-5-[6-amino-2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C21H22N6O5
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1
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| 1 |
EC50 = 2400 nM
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CP0458861
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(2R,3R,4S,5R)-2-[6-amino-2-(3-hydroxy-3-phenylprop-1-ynyl)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C19H19N5O5
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1
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| 1 |
EC50 = 2400 nM
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CP0404601
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(2R,3R,4S,5R)-2-[2-chloro-6-(furan-2-ylmethylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C17H18ClN9O4
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1
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| 1 |
EC50 = 2570 nM
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CP0425050
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(2R,3R,4S,5R)-2-(2-(2-(1H-pyrrol-3-yl)ethoxy)-6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C16H20N6O5
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1
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| 1 |
EC50 = 2580 nM
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CP0529338
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3S)-3-hydroxy-3-phenylprop-1-ynyl]-6-(methylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C20H21N5O5
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1
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| 1 |
EC50 = 2600 nM
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CP0849861
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2-Hydroxymethyl-5-[2-(3-hydroxy-3-phenyl-prop-1-ynyl)-6-methylamino-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
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C20H21N5O5
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1
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| 1 |
EC50 = 2700 nM
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CP0384690
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(2R,3R,4S,5R)-2-[2-chloro-6-(oxolan-2-ylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C16H20ClN9O4
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1
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| 1 |
EC50 = 3150 nM
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CP0428358
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(2R,3R,4S,5R)-2-[6-(ethylamino)-2-[2-(1H-indol-3-yl)ethoxy]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C22H26N6O5
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1
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| 1 |
EC50 = 3270 nM
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CP0304014
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2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Show/Hide
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C14H10N6O2
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1
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| 1 |
EC50 = 3420 nM
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CP0471400
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(2R,3R,4S,5R)-2-(6-amino-2-phenethoxy-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C18H21N5O5
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1
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| 1 |
EC50 = 3490 nM
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CP0397896
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(2R,3R,4S,5R)-2-[2-chloro-6-(methylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C13H16ClN9O3
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1
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| 1 |
EC50 = 3510 nM
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CP0454464
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(2R,3R,4S,5S)-2-[6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol
Show/Hide
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C16H14Cl2FN5O3
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1
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| 1 |
EC50 = 3740 nM
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CP0372684
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(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-2-(4-chloro-phenyl)-1-hydroxymethyl-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol
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C21H25ClN10O4
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1
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| 1 |
EC50 = 4700 nM
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CP0436337
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[(3,5-ditert-butyl-4-hydroxybenzoyl)amino]phenyl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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C35H46N8O6
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1
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| 1 |
EC50 = 6069 nM
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CP0054093
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tert-butyl 1-[(2R,3S)-3-[[(2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoyl]amino]-2-hydroxy-4-phenylbutyl]pyrrolidine-2-carboxylate
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C31H42N4O7
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1
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| 1 |
EC50 = 6100 nM
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CP0859556
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2-Hydroxymethyl-5-[2-(3-hydroxy-3-phenyl-prop-1-ynyl)-6-isopropylamino-purin-9-yl]-tetrahydro-furan-3,4-diol
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C22H25N5O5
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1
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| 1 |
EC50 = 6100 nM
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CP0421969
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(2R,3R,4S,5R)-2-[6-amino-2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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C19H19N5O5
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1
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| 1 |
EC50 = 6200 nM
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CP0424294
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(2S,3S,4R,5R)-5-[2-[2-[4-[(3,5-ditert-butyl-4-hydroxybenzoyl)amino]phenyl]ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
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C48H56N8O6
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1
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| 1 |
EC50 = 6694 nM
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CP0398111
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-iodophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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C24H32IN9O4
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1
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| 1 |
EC50 = 7130 nM
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CP0480143
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1-[2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-3-phenylurea
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C21H15N7O3
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1
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| 1 |
EC50 = 8870 nM
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CP0435733
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]-6-(propan-2-ylamino)purin-9-yl]oxolane-3,4-diol
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C22H25N5O5
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1
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| 1 |
EC50 = 8900 nM
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CP0394564
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(2R,3R,4S,5R)-2-[6-(ethylamino)-2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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C21H23N5O5
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1
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| 1 |
EC50 = 9100 nM
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CP0418021
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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C24H32ClN9O4
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1
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| 1 |
EC50 = 9287 nM
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CP0398115
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-bromophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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C24H32BrN9O4
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1
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| 1 |
EC50 = 9352 nM
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CP0378926
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(1S,2R,3S,4R,5S)-4-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C18H23ClN6O3
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1
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| 1 |
EC50 > 10000 nM
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CP0847898
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(1S,2R,3S,4R,5S)-4-(6-(cyclopentylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C18H24N6O3
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1
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| 1 |
EC50 > 10000 nM
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CP0847899
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(1S,2R,3S,4R,5S)-4-(6-(bicyclo[2.2.1]heptan-7-ylamino)-2-chloro-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C20H25ClN6O3
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1
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| 1 |
EC50 > 10000 nM
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CP0041258
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(CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmethyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-ylamino]-ethyl}-phenyl)-propionic acid
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C23H29N7O6
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Ki > 10000 nM
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CP0387446
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(1R,2S,3R,5S)-3-(2-(2-(1-ethyl-1H-imidazol-4-yl)ethylamino)-6-(2-ethylbutylamino)-9H-purin-9-yl)-5-(4-(hydroxymethyl)-1H-pyrazol-1-yl)cyclopentane-1,2-diol
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C27H40N10O3
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1
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| 1 |
EC50 > 10000 nM
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CP0417873
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N-[(1S,2R,3S,4R)-4-[6-(2,2-diphenylethylamino)-2-[2-(1H-imidazol-5-yl)ethylamino]purin-9-yl]-2,3-dihydroxycyclopentyl]propanamide
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C32H37N9O3
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1
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| 1 |
EC50 > 10000 nM
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CP0417891
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(2R,3R,4S,5S)-2-(6-amino-2-((S)-1-hydroxy-3-phenylpropan-2-ylamino)-9H-purin-9-yl)-5-(4-ethyl-1H-pyrazol-1-yl)tetrahydrofuran-3,4-diol
Show/Hide
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C24H30N8O3
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1
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| 1 |
EC50 > 10000 nM
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CP0422037
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N-[(1S,2R,3S,4R)-4-(6-amino-2-hex-1-ynylpurin-9-yl)-2,3-dihydroxycyclopentyl]propanamide
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C19H26N6O3
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1
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| 1 |
EC50 > 10000 nM
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CP0439091
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(2R,3R,4S,5S)-2-(6-amino-2-((S)-1-hydroxy-3-phenylpropan-2-ylamino)-9H-purin-9-yl)-5-(4-methyl-1H-pyrazol-1-yl)tetrahydrofuran-3,4-diol
Show/Hide
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C23H28N8O3
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1
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| 1 |
EC50 > 10000 nM
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CP0506330
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N-[(1S,2R,3S,4R)-4-[2-[2-(1-ethylimidazol-4-yl)ethylamino]-6-(pentan-3-ylamino)purin-9-yl]-2,3-dihydroxycyclopentyl]propanamide
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C25H39N9O3
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1
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| 1 |
EC50 > 10000 nM
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CP0199235
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(2R,3R,4S)-2-(6-amino-2-(hex-1-ynyl)-9H-purin-9-yl)tetrahydrothiophene-3,4-diol
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C15H19N5O2S
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1
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| 1 |
EC50 = 10000 nM
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CP0397950
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H31Cl2N9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0397951
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-fluorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H32FN9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0398108
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(2-chlorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H32ClN9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0398112
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(3-chloro-4-fluorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H31ClFN9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0398113
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H35N9O5
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1
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| 1 |
EC50 > 10000 nM
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CP0398114
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H32F3N9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0398116
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(2S,3S,4R,5R)-5-[6-amino-2-[3-(4-phenylpiperazin-1-yl)propylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H35N9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0398117
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(2-phenylethyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C26H37N9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0399646
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-nitrophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H32N10O6
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1
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| 1 |
EC50 > 10000 nM
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CP0399647
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-methoxyphenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H35N9O5
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1
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| 1 |
EC50 > 10000 nM
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CP0399648
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(3,5-dichlorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H31Cl2N9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0399649
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(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H34N8O6
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1
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| 1 |
EC50 > 10000 nM
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CP0399651
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ethyl 2-[4-[4-[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]piperazin-1-yl]phenoxy]acetate
Show/Hide
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C26H34N8O7
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1
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| 1 |
EC50 > 10000 nM
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CP0399652
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(2S,3S,4R,5R)-5-[6-amino-2-(4-phenylpiperazin-1-yl)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C22H28N8O4
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1
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| 1 |
EC50 > 10000 nM
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CP0399654
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(2S,3S,4R,5R)-5-[6-amino-2-[4-(4-methoxyphenyl)piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C23H30N8O5
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1
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| 1 |
EC50 > 10000 nM
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CP0399664
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C27H39N9O6
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1
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| 1 |
EC50 > 10000 nM
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CP0399789
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(2S,3S,4R,5R)-5-[6-amino-2-[4-(4-fluorophenyl)piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C22H27FN8O4
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1
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| 1 |
EC50 > 10000 nM
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CP0418022
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-chloro-2-fluorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H31ClFN9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0441596
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-methylphenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H35N9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0448231
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(2S,3S,4R,5R)-5-[6-amino-2-[2-(4-phenylpiperazin-1-yl)ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H33N9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0448232
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2-[4-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]piperazin-1-yl]phenyl]acetic acid
Show/Hide
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C26H35N9O6
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1
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| 1 |
EC50 > 10000 nM
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CP0448233
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(2-fluorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H32FN9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0448234
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H32F3N9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0448235
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H32ClN9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0448236
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2-[4-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]piperazin-1-yl]-3-bromophenyl]acetic acid
Show/Hide
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C26H34BrN9O6
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1
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| 1 |
EC50 > 10000 nM
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CP0452790
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(2S,3S,4R,5R)-5-[6-amino-2-[2-(4-benzylpiperazin-1-yl)ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H35N9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0452791
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4-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]piperazin-1-yl]benzoic acid
Show/Hide
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C25H33N9O6
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1
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| 1 |
EC50 > 10000 nM
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CP0452792
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3-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]piperazin-1-yl]benzoic acid
Show/Hide
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C25H33N9O6
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1
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| 1 |
EC50 > 10000 nM
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CP0452793
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(2,3-difluorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H31F2N9O4
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1
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| 1 |
EC50 > 10000 nM
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CP0452794
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(2S,3S,4R,5R)-5-[6-amino-2-[4-(4-phenylmethoxyphenyl)piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C29H34N8O5
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1
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| 1 |
EC50 > 10000 nM
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CP0452796
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(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-[(4-fluorophenyl)methoxy]phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C29H33FN8O5
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1
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| 1 |
EC50 > 10000 nM
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CP0461003
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(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-(pyridin-4-ylmethoxy)phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C28H33N9O5
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1
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| 1 |
EC50 > 10000 nM
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CP0414024
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5-methyl-1-(oxolan-2-ylmethyl)-3-(2-phenylethyl)thieno[2,3-d]pyrimidine-2,4-dione
Show/Hide
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C20H22N2O3S
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1
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| 1 |
EC50 > 10000 nM
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CP0436339
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(2S,3S,4R,5R)-5-[6-(2,2-diphenylethylamino)-2-[2-[4-[5-[(3S)-dithiolan-3-yl]pentanoylamino]phenyl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C42H50N8O5S2
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1
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| 1 |
EC50 = 12160 nM
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CP0454469
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(2S,3S,4R,5R)-2-(chloromethyl)-5-[6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]oxolane-3,4-diol
Show/Hide
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C14H18ClN5O4
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1
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| 1 |
EC50 = 12800 nM
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CP0429743
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2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Show/Hide
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C9H8N6OS
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1
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| 1 |
EC50 = 14900 nM
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CP0433633
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1-(2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl)-3-p-tolylurea
Show/Hide
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C17H15N7O2S
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1
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| 1 |
EC50 = 16800 nM
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CP0875854
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2-chloro-N6-cyclopentyladenosine
Show/Hide
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C17H23ClN6O4
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2
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| 1 |
EC50 = 16850 nM
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| 2 |
Ki = 18800 nM
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CP0433632
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1-(2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl)-3-phenylurea
Show/Hide
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C16H13N7O2S
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1
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| 1 |
EC50 = 17100 nM
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CP0502848
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1-(2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl)-3-phenylurea
Show/Hide
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C22H17N7O3
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1
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| 1 |
EC50 = 20000 nM
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CP0454470
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(2S,3S,4R,5R)-2-(chloromethyl)-5-[2-chloro-6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]oxolane-3,4-diol
Show/Hide
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C14H17Cl2N5O4
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1
|
| 1 |
EC50 = 20000 nM
|
|
|
|
CP0001102
|
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C10H13N5O4
|
1
|
| 1 |
EC50 = 24000 nM
|
|
|
|
CP0397903
|
(2R,3R,4S,5R)-2-[6-[[(1R,2S,4R)-2-bicyclo[2.2.1]heptanyl]amino]-2-chloropurin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H24ClN9O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0437158
|
(2R,3R,4S,5R)-2-[6-(cyclopentylamino)-2-(3,5-dimethylphenyl)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C28H35N7O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0437161
|
(2R,3R,4S,5R)-2-[6-(2-bicyclo[2.2.1]heptanylamino)-2-chloropurin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C22H28ClN7O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0437166
|
(2R,3R,4S,5R)-2-[6-(2-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C22H29N7O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0454467
|
(2R,3R,4S,5R)-2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C20H26ClN7O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0389278
|
(2R,3R,4S,5R)-2-[2-chloro-6-[(4-chloro-2-fluorophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H18Cl2FN9O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0374258
|
7-Amino-5-dimethylammino-2-(2-furyl)-[1,2,4]triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C10H11N7O
|
1
|
| 1 |
EC50 = 33700 nM
|
|
|
|
CP0436336
|
(2S,3S,4R,5R)-5-[2-[2-[4-[(3,5-ditert-butyl-4-hydroxybenzoyl)amino]phenyl]ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C49H58N8O6
|
1
|
| 1 |
EC50 = 40310 nM
|
|
|
|
CP0430858
|
2-(2-Furyl)-7-[4-(methoxyphenyl)acetyl]amino-5-methylthio[1,2,4]triazolo[1,5-a][1,3,5]triazine
Show/Hide
|
C18H16N6O3S
|
1
|
| 1 |
EC50 = 42400 nM
|
|
|
|
CP0437159
|
(2R,3R,4S,5R)-2-[2-chloro-6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C21H20Cl2FN7O3
|
1
|
| 1 |
EC50 > 60000 nM
|
|
|
|
CP0437160
|
(2R,3R,4S,5R)-2-[6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C21H21ClFN7O3
|
1
|
| 1 |
EC50 > 60000 nM
|
|
|
|
CP0437163
|
(2R,3R,4S,5R)-2-[6-(2-bicyclo[2.2.1]heptanylamino)-2-(3,5-dimethylphenyl)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C30H37N7O3
|
1
|
| 1 |
EC50 > 60000 nM
|
|
|
|
CP0437168
|
(2R,3R,4S,5R)-2-[6-(4-chloro-2-fluoroanilino)-2-(3,5-dimethylphenyl)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C29H29ClFN7O3
|
1
|
| 1 |
EC50 > 60000 nM
|
|
|
|
CP0454462
|
(2R,3R,4S,5R)-2-[2-chloro-6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C19H24ClN7O4
|
1
|
| 1 |
EC50 > 60000 nM
|
|
|
|
CP0454463
|
(2R,3S,4R,5R)-2-[(3,5-dimethylpyrazol-1-yl)methyl]-5-[6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C19H25N7O4
|
1
|
| 1 |
EC50 > 60000 nM
|
|
|
|
CP0454468
|
(2R,3R,4S,5R)-2-[2-(3,5-dimethylphenyl)-6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C27H33N7O4
|
1
|
| 1 |
EC50 > 60000 nM
|
|
|
|
CP0463904
|
(2R,3R,4S,5S)-2-[2-chloro-6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol
Show/Hide
|
C16H13Cl3FN5O3
|
1
|
| 1 |
EC50 > 60000 nM
|
|
|
|
CP0552686
|
(2R,3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C20H27N7O3
|
1
|
| 1 |
EC50 > 60000 nM
|
|
|
|
CP0849991
|
(2R,3R,4S,5R)-2-(6-amino-8-(hex-1-ynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Show/Hide
|
C16H21N5O4
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0885586
|
8-(2-phenylethynyl)adenosine
Show/Hide
|
C18H17N5O4
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0887833
|
(E)-3-[6-Amino-9-((3S,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-8-yl]-1-phenyl-propenone
Show/Hide
|
C19H19N5O5
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0199236
|
(2R,3R,4S,5R)-2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C16H21N5O4
|
1
|
| 1 |
EC50 = 100000 nM
|
|
|
|
CP0241358
|
(2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin-3-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide
Show/Hide
|
C20H20N6O4
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0270742
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(methylamino)-2-(phenylethynyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
Show/Hide
|
C19H19N5O4
|
1
|
| 1 |
EC50 = 100000 nM
|
|
|
|
CP0270772
|
(2R,3R,4S,5R)-2-(6-amino-2-(phenylethynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Show/Hide
|
C18H17N5O4
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0394227
|
(2R,3R,4S,5R)-2-[2-hex-1-ynyl-6-(propan-2-ylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C19H27N5O4
|
1
|
| 1 |
EC50 = 100000 nM
|
|
|
|
CP0394490
|
(2R,3R,4S,5R)-2-[6-(ethylamino)-2-hex-1-ynylpurin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C18H25N5O4
|
1
|
| 1 |
EC50 = 100000 nM
|
|
|
|
CP0394507
|
(2R,3R,4S,5R)-2-[2-hex-1-ynyl-6-(methylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C17H23N5O4
|
1
|
| 1 |
EC50 = 100000 nM
|
|
|
|
CP0445263
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]-6-(methylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C20H21N5O5
|
1
|
| 1 |
EC50 = 100000 nM
|
|
|
|
CP0448419
|
(3R,4S,5R)-2-[6-(ethylamino)-2-(2-phenylethynyl)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C20H21N5O4
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0860185
|
2-Hydroxymethyl-5-(6-isopropylamino-2-phenylethynyl-purin-9-yl)-tetrahydro-furan-3,4-diol
Show/Hide
|
C21H23N5O4
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0376406
|
5-Dimethylamino-2-(2-furyl)-7-phenylacetylamino-[1,2,4]triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C18H17N7O2
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0376407
|
5-Dimethylamino-7-diphenylacetylamino-2-(2-furyl)-[1,2,4]triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C24H21N7O2
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0389767
|
5-Dimethylamino-2-(2-furyl)-7-[4-(methoxyphenyl)-acetyl]amino-[1,2,4]triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C19H19N7O3
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0428857
|
2-(2-Furyl)-7-n-pentylcarbonylamino-5-phenoxy[1,2,4]-triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C20H20N6O3
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0470125
|
2-(2-Furyl)-5-methylthio-7-phenylacetylamino[1,2,4]-triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C17H14N6O2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0477258
|
1-(5-(dimethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl)-3-p-tolylurea
Show/Hide
|
C18H18N8O2
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0491268
|
2-(2-Furyl)-5-methylthio-7-n-pentylcarbonylamino-[1,2,4]-triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C15H18N6O2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0496116
|
5-Dimethylamino-2-(2-furyl)-7-n-pentylcarbonylamino-[1,2,4]triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C16H21N7O2
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0502847
|
7-Diphenylacetylamino-2-(2-furyl)-5-phenoxy[1,2,4]-triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C28H20N6O3
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0502851
|
2-(2-Furyl)-7-[4-(methoxyphenyl)acetyl]amino-5-phenoxy[1,2,4]triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C23H18N6O4
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0510834
|
7-Diphenyl-acetylamino-2-(2-furyl)-5-methylthio[1,2,4]-triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C23H18N6O2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0510835
|
2-(2-Furyl)-5-phenoxy 7-phenylacetylamino-[1,2,4]triazolo[1,5-a]-[1,3,5]triazine
Show/Hide
|
C22H16N6O3
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0513278
|
1-(5-(dimethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl)-3-phenylurea
Show/Hide
|
C17H16N8O2
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0058033
|
1,3-dipropyl-8-cyclopentylxanthine
Show/Hide
|
C16H24N4O2
|
4
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 3.8 nM
|
|
|
| 3 |
IC50 = 43 nM
|
|
|
| 4 |
Ki = 1000 nM
|
|
|
|
CP0135320
|
methyl 2-[6-amino-3,5-dicyano-4-(furan-2-yl)pyridin-2-yl]sulfanylacetate
Show/Hide
|
C14H10N4O3S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0332764
|
benzyl 2-[6-amino-3,5-dicyano-4-(furan-2-yl)pyridin-2-yl]sulfanylacetate
Show/Hide
|
C20H14N4O3S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383003
|
2-amino-4-(furan-2-yl)-6-(pyridin-2-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C17H11N5OS
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383006
|
2-amino-4-(furan-2-yl)-6-(pyridin-3-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C17H11N5OS
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383007
|
2-amino-4-(furan-2-yl)-6-(2-hydroxyethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C13H10N4O2S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383011
|
2-amino-4-(furan-2-yl)-6-(pyridin-4-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C17H11N5OS
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383015
|
methyl 3-[(6-amino-3,5-dicyano-4-pyridin-3-ylpyridin-2-yl)sulfanylmethyl]benzoate
Show/Hide
|
C21H15N5O2S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383016
|
2-amino-6-(2-hydroxyethylsulfanyl)-4-thiophen-3-ylpyridine-3,5-dicarbonitrile
Show/Hide
|
C13H10N4OS2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383017
|
2-amino-6-(2-hydroxyethylamino)-4-thiophen-2-ylpyridine-3,5-dicarbonitrile
Show/Hide
|
C13H11N5OS
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383019
|
2-amino-4-(furan-2-yl)-6-[[3-(hydroxymethyl)phenyl]methylsulfanyl]pyridine-3,5-dicarbonitrile
Show/Hide
|
C19H14N4O2S
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 152 nM
|
|
|
|
CP0383020
|
2-amino-4-(furan-2-yl)-6-phenacylsulfanylpyridine-3,5-dicarbonitrile
Show/Hide
|
C19H12N4O2S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383022
|
2-amino-6-(cyanomethylsulfanyl)-4-(furan-2-yl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C13H7N5OS
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383050
|
2-amino-6-[(3-cyanophenyl)methylsulfanyl]-4-(furan-2-yl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C19H11N5OS
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0426219
|
2-[6-amino-3,5-dicyano-4-(furan-2-yl)pyridin-2-yl]sulfanylacetamide
Show/Hide
|
C13H9N5O2S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0434145
|
methyl 3-[[6-amino-3,5-dicyano-4-(furan-3-yl)pyridin-2-yl]sulfanylmethyl]benzoate
Show/Hide
|
C20H14N4O3S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0434147
|
2-(benzylamino)-4-(furan-2-yl)-6-(2-hydroxyethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C20H16N4O2S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0439989
|
3-[[6-amino-3,5-dicyano-4-(furan-2-yl)pyridin-2-yl]sulfanylmethyl]benzamide
Show/Hide
|
C19H13N5O2S
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
IC50 = 13 nM
|
|
|
|
CP0439992
|
2-(cyclopentylamino)-4-(furan-2-yl)-6-(2-hydroxyethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C18H18N4O2S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0443817
|
2-amino-6-(2-hydroxyethylsulfanyl)-4-pyridin-3-ylpyridine-3,5-dicarbonitrile
Show/Hide
|
C14H11N5OS
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0443821
|
4-(furan-2-yl)-2-(2-hydroxyethylsulfanyl)-6-(4-iodoanilino)pyridine-3,5-dicarbonitrile
Show/Hide
|
C19H13IN4O2S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0455735
|
2-(cyclopropylamino)-4-(furan-2-yl)-6-(2-hydroxyethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C16H14N4O2S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0460938
|
2-amino-6-(2-hydroxyethylamino)-4-pyridin-3-ylpyridine-3,5-dicarbonitrile
Show/Hide
|
C14H12N6O
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0463666
|
3-[[6-amino-3,5-dicyano-4-(furan-2-yl)pyridin-2-yl]sulfanylmethyl]benzoic acid
Show/Hide
|
C19H12N4O3S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0473103
|
2-amino-4-(furan-2-yl)-6-(2-hydroxyethoxy)pyridine-3,5-dicarbonitrile
Show/Hide
|
C13H10N4O3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0473109
|
N-[3,5-dicyano-4-(furan-2-yl)-6-(2-hydroxyethylsulfanyl)pyridin-2-yl]acetamide
Show/Hide
|
C15H12N4O3S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0473110
|
methyl 5-[[6-amino-3,5-dicyano-4-(furan-2-yl)pyridin-2-yl]sulfanylmethyl]furan-2-carboxylate
Show/Hide
|
C18H12N4O4S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0477262
|
methyl 3-[[6-amino-3,5-dicyano-4-(furan-2-yl)pyridin-2-yl]sulfanylmethyl]benzoate
Show/Hide
|
C20H14N4O3S
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
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CP0477263
|
2-amino-4-(furan-2-yl)-6-(2-hydroxyethylamino)pyridine-3,5-dicarbonitrile
Show/Hide
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C13H11N5O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0383333
|
1-deoxy-1-{6-[N'-(pyridine-3-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C18H20N8O5
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0408626
|
1-deoxy-1-{6-[N'-(1-methyl-4-nitro-1H-imidazole-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C17H20N10O7
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0408811
|
1-deoxy-1-[6-(N'-benzoyl-hydrazino)-2-chloro-9H-purin-9-yl]-N-ethyl-beta-Dribofuranuronamide
Show/Hide
|
C19H20ClN7O5
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0441868
|
1-deoxy-1-{2-chloro-6-[N'-(5-methyl-isoxazole-3-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C17H19ClN8O6
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0442338
|
1-deoxy-1-{2-chloro-6-[N'-(5-phenyl-isoxazole-3-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C22H21ClN8O6
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0445616
|
1-deoxy-1-[6-(N'-(4-chlorobenzoyl)hydrazino)-9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C19H20ClN7O5
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0499897
|
1-deoxy-1-[6-(N'-benzoylhydrazino)-9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C19H21N7O5
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0472319
|
4-[4-[2-[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]piperazin-1-yl]benzenesulfonamide
Show/Hide
|
C21H24N8O3S2
|
2
|
| 1 |
IC50 = 0.34 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0377686
|
8-(4-(4-(4-Chlorophenyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25ClN6O4S
|
6
|
| 1 |
IC50 = 0.534 nM
|
|
|
| 2 |
IC50 = 0.739 nM
|
|
|
| 3 |
IC50 = 18.3 nM
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|
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| 4 |
Kd = 0.403 nM
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| 5 |
Kd = 0.652 nM
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| 6 |
Ki = 0.553 nM
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CP0529133
|
8-[4-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propylpurine-2,6-dione
Show/Hide
|
C25H25ClN6O4S
|
1
|
| 1 |
IC50 = 1.06 nM
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|
|
|
CP0847642
|
3-phenyl[1,2,4]triazino[4,3-a]benzimidazol-4-(10H)-one
Show/Hide
|
C15H10N4O
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0399804
|
10-(4-chlorophenyl)-3-(furan-2-yl)-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Show/Hide
|
C19H11ClN4O2
|
1
|
| 1 |
IC50 = 2.11 nM
|
|
|
|
CP0416457
|
10-(4-chlorophenyl)-3-phenyl-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Show/Hide
|
C21H13ClN4O
|
1
|
| 1 |
IC50 = 2.42 nM
|
|
|
|
CP0378166
|
3-phenyl-10-(2-phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Show/Hide
|
C23H18N4O
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0416922
|
7-chloro-3,10-diphenyl-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Show/Hide
|
C21H13ClN4O
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0864769
|
2-(Furan-2-yl)-N5-[2-(pyridin-3-yl)ethyl][1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C16H14N6OS
|
1
|
| 1 |
IC50 = 4.21 nM
|
|
|
|
CP0339232
|
4-[2-[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]benzenesulfonamide
Show/Hide
|
C17H16N6O3S2
|
2
|
| 1 |
IC50 = 5.2 nM
|
|
|
| 2 |
IC50 = 34 nM
|
|
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|
CP0424404
|
3-(furan-2-yl)-10-(2-phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Show/Hide
|
C21H16N4O2
|
1
|
| 1 |
IC50 = 5.34 nM
|
|
|
|
CP0137617
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-1-[[3-(trifluoromethyl)phenyl]methyl]pyrazole-4-carboxamide
Show/Hide
|
C24H22F3N5O3S
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
|
CP0403600
|
8-[3-[(6-chloro-1H-benzimidazol-2-yl)methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C22H22ClN7O4
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0377196
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-1H-pyrrole-3-carboxamide
Show/Hide
|
C17H18N4O3S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0406021
|
methyl 2-[acetyl-[2-[(4-fluorobenzoyl)amino]-4-methoxy-1,3-benzothiazol-7-yl]amino]acetate
Show/Hide
|
C20H18FN3O5S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0204348
|
N-[(1R,3R)-3-[[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]carbamoyl]cyclopentyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C26H27F3N4O4S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0217285
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
Show/Hide
|
C25H27F3N4O4S
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
Ki = 5 nM
|
|
|
|
CP0284154
|
N-[(1S,3R)-3-[[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]carbamoyl]cyclopentyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C26H27F3N4O4S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0387790
|
8-[3-[(5-chloro-6-fluoro-1H-benzimidazol-2-yl)methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C22H21ClFN7O4
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0408077
|
2-(furan-2-yl)-5-N-(thiophen-3-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C14H11N5OS2
|
1
|
| 1 |
IC50 = 8.96 nM
|
|
|
|
CP0403598
|
6-(2-methyl-5-oxo-1H-pyrazol-3-yl)-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
|
C16H21N5O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0410255
|
10-benzyl-3-furan-2-yl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
|
C20H14N4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0391931
|
8-[3-[(6-bromo-1H-benzimidazol-2-yl)methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C22H22BrN7O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0371895
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-fluorobenzamide
Show/Hide
|
C19H18FN3O3S
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
|
CP0388260
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-1-[(3-fluorophenyl)methyl]pyrazole-4-carboxamide
Show/Hide
|
C23H22FN5O3S
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
Ki = 6 nM
|
|
|
|
CP0472456
|
1-N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-N-(2-methoxyethyl)-4-N-methylbenzene-1,4-dicarboxamide
Show/Hide
|
C24H28N4O5S
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
|
CP0312089
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-[[3-(trifluoromethyl)phenyl]sulfonylamino]cyclohexane-1-carboxamide
Show/Hide
|
C26H29F3N4O5S2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0389063
|
2-(furan-2-yl)-5-N-(pyrazin-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C14H11N7OS
|
1
|
| 1 |
IC50 = 13.2 nM
|
|
|
|
CP0313558
|
(R)-N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-1-(3-(trifluoromethyl)benzoyl)pyrrolidine-3-carboxamide
Show/Hide
|
C25H25F3N4O4S
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0411540
|
2-(furan-2-yl)-5-N-[2-(furan-2-yl)ethyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H13N5O2S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0377190
|
4-fluoro-N-(4-methoxy-7-(N-methylacetamido)benzo[d]thiazol-2-yl)benzamide
Show/Hide
|
C18H16FN3O3S
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
Ki = 22 nM
|
|
|
|
CP0462139
|
8-[5-[(6-chloro-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C23H25ClN8O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0142536
|
3,10-Diphenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
|
C21H14N4O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0847643
|
3-(2-furyl)[1,2,4]triazino[4,3-a]benzimidazol-4-(10H)-one
Show/Hide
|
C13H8N4O2
|
1
|
| 1 |
IC50 = 15.3 nM
|
|
|
|
CP0371900
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-(piperidine-1-carbonyl)benzamide
Show/Hide
|
C25H28N4O4S
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
|
CP0417790
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-(pyrrolidine-1-carbonyl)benzamide
Show/Hide
|
C24H26N4O4S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0313557
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-[[3-(trifluoromethyl)phenyl]sulfonylamino]cyclohexane-1-carboxamide
Show/Hide
|
C26H29F3N4O5S2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0204346
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-1-[3-(trifluoromethyl)benzoyl]piperidine-4-carboxamide
Show/Hide
|
C26H27F3N4O4S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0238714
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
Show/Hide
|
C25H27F3N4O3S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0446616
|
4-[2-[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H15N5O3S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0425918
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-imidazol-1-ylbenzamide
Show/Hide
|
C22H21N5O3S
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0436825
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-[[methyl(methylsulfonyl)amino]methyl]benzamide
Show/Hide
|
C22H26N4O5S2
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
|
CP0439012
|
4-fluoro-N-(7-(N-isopropylacetamido)-4-methoxybenzo[d]thiazol-2-yl)benzamide
Show/Hide
|
C20H20FN3O3S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0731646
|
cis-N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-3-(3-(trifluoromethyl)benzylamino)cyclopentanecarboxamide 2,2,2-trifluoroacetate
Show/Hide
|
C28H30F6N4O5S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0204349
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-[3-(trifluoromethyl)phenyl]sulfonylpiperidine-1-carboxamide
Show/Hide
|
C25H27F3N4O5S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0403597
|
8-(2-methyl-5-oxo-1H-pyrazol-3-yl)-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C15H20N6O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0424402
|
3-furan-2-yl-10-methyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
|
C14H10N4O2
|
1
|
| 1 |
IC50 = 20.4 nM
|
|
|
|
CP0164878
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-2-methylpyrazole-3-carboxamide
Show/Hide
|
C17H19N5O3S
|
2
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0371897
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-pyrazol-1-ylbenzamide
Show/Hide
|
C22H21N5O3S
|
2
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0377197
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-1H-pyrazole-4-carboxamide
Show/Hide
|
C16H17N5O3S
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0438977
|
4-N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-1-N-methylbenzene-1,4-dicarboxamide
Show/Hide
|
C21H22N4O4S
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0472455
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-(morpholine-4-carbonyl)benzamide
Show/Hide
|
C24H26N4O5S
|
2
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0377192
|
N-[7-[acetyl(ethyl)amino]-4-chloro-1,3-benzothiazol-2-yl]-4-fluorobenzamide
Show/Hide
|
C18H15ClFN3O2S
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0406020
|
4-fluoro-N-(7-(N-isobutylacetamido)-4-methoxybenzo[d]thiazol-2-yl)benzamide
Show/Hide
|
C21H22FN3O3S
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0557707
|
8-[4-(4-benzylpiperazin-1-yl)sulfonylphenyl]-1-propylpurine-2,6-dione
Show/Hide
|
C25H26N6O4S
|
1
|
| 1 |
IC50 = 23.5 nM
|
|
|
|
CP0415415
|
3-[[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]methyl]phenol
Show/Hide
|
C16H13N5O2S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0451425
|
3-[2-[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]phenol
Show/Hide
|
C17H15N5O2S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0284217
|
N-[4-[[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]carbamoyl]cyclohexyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C27H29F3N4O4S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0496331
|
8-[5-[[4-chloro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C24H24ClF3N8O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0395751
|
11-(furan-2-yl)-4-(2-phenylethyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-amine
Show/Hide
|
C18H15N7O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0387799
|
6-[5-(1H-benzimidazol-2-ylmethoxy)-2-methylpyrazol-3-yl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
|
C24H27N7O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0438976
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-(tetrazol-1-yl)benzamide
Show/Hide
|
C20H19N7O3S
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
Ki = 23 nM
|
|
|
|
CP0454301
|
4-cyano-N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)benzamide
Show/Hide
|
C20H18N4O3S
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0475417
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-[(2-oxopyrrolidin-1-yl)methyl]benzamide
Show/Hide
|
C24H26N4O4S
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
|
CP0199266
|
N-[4-[[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]carbamoyl]cyclohexyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C27H29F3N4O4S
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0340021
|
4-[[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]methyl]benzenesulfonamide
Show/Hide
|
C16H14N6O3S2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0377193
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-1-methylpyrazole-4-carboxamide
Show/Hide
|
C17H19N5O3S
|
2
|
| 1 |
IC50 = 29 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0761378
|
trans-N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-4-(3-(trifluoromethyl)benzylamino)cyclohexanecarboxamide 2,2,2-trifluoroacetate
Show/Hide
|
C29H32F6N4O5S
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0385422
|
11-(furan-2-yl)-3-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-amine
Show/Hide
|
C11H9N7O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0427814
|
11-(furan-2-yl)-4-(3-phenylpropyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-amine
Show/Hide
|
C19H17N7O
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0462700
|
1-[11-(furan-2-yl)-3-propyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
|
C21H20N8O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0391927
|
8-[5-[(5-chloro-6-fluoro-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C23H24ClFN8O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0415419
|
5-N-benzyl-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C16H13N5OS
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0377195
|
4-fluoro-N-(4-methoxy-7-(N-(2-methoxyethyl)acetamido)benzo[d]thiazol-2-yl)benzamide
Show/Hide
|
C20H20FN3O4S
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0441294
|
11-(furan-2-yl)-4-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-amine
Show/Hide
|
C11H9N7O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0864770
|
2-(Furan-2-yl)-N5-(pyridin-4-yl-methyl)[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H12N6OS
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0436824
|
methyl 4-[[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]carbamoyl]benzoate
Show/Hide
|
C21H21N3O5S
|
2
|
| 1 |
IC50 = 35 nM
|
|
|
| 2 |
Ki = 15 nM
|
|
|
|
CP0391930
|
ethyl 2-[[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxymethyl]-3H-benzimidazole-5-carboxylate
Show/Hide
|
C26H30N8O5
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0438975
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-methylsulfonylbenzamide
Show/Hide
|
C20H21N3O5S2
|
2
|
| 1 |
IC50 = 36 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0439007
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-(methanesulfonamido)benzamide
Show/Hide
|
C20H22N4O5S2
|
2
|
| 1 |
IC50 = 37 nM
|
|
|
| 2 |
Ki = 22 nM
|
|
|
|
CP0099921
|
N-(1,3-benzodioxol-5-yl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
|
C24H27N7O6
|
2
|
| 1 |
IC50 = 38 nM
|
|
|
| 2 |
Ki = 5.5 nM
|
|
|
|
CP0472457
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-(4-methylpiperazine-1-carbonyl)benzamide
Show/Hide
|
C25H29N5O4S
|
2
|
| 1 |
IC50 = 38 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0403602
|
8-[2-methyl-5-[[6-(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C24H25F3N8O3
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0463678
|
N-(3,4-dimethylphenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
|
C25H31N7O4
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0439004
|
4-fluoro-N-(4-methoxy-7-(N-(2,2,2-trifluoroethyl)acetamido)benzo[d]thiazol-2-yl)benzamide
Show/Hide
|
C19H15F4N3O3S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0393765
|
11-(furan-2-yl)-3-propyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-amine
Show/Hide
|
C13H13N7O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0352031
|
(S)-N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-1-(3-(trifluoromethyl)benzoyl)pyrrolidine-3-carboxamide
Show/Hide
|
C25H25F3N4O4S
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0438989
|
4-fluoro-N-(7-(N-(3-hydroxypropyl)acetamido)-4-methoxybenzo[d]thiazol-2-yl)benzamide
Show/Hide
|
C20H20FN3O4S
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0295149
|
(R)-N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-1-(3-(trifluoromethyl)phenylsulfonyl)pyrrolidine-3-carboxamide
Show/Hide
|
C24H25F3N4O5S2
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0403543
|
4-(furan-2-yl)-11-methyl-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C12H10N6O
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0371891
|
N-(4-chlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
|
C23H26ClN7O3
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0387800
|
2-[5-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)-1-methylpyrazol-3-yl]oxy-N-(4-fluorophenyl)acetamide
Show/Hide
|
C24H27FN6O4
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0294441
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-1-[[3-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
Show/Hide
|
C26H29F3N4O3S
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0392049
|
11-(furan-2-yl)-4-propyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-amine
Show/Hide
|
C13H13N7O
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0418732
|
8-[2-methyl-5-[(6-methyl-1H-benzimidazol-2-yl)methoxy]pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C24H28N8O3
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0374815
|
N-(3,4-dimethoxyphenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
|
C25H31N7O6
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0463046
|
4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C19H16N6O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0420605
|
2-(furan-2-yl)-5-N-[2-(3-methoxyphenyl)ethyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C18H17N5O2S
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0053494
|
4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]amino}ethyl)phenol
Show/Hide
|
C16H15N7O2
|
4
|
| 1 |
IC50 = 48 nM
|
|
|
| 2 |
IC50 = 51 nM
|
|
|
| 3 |
IC50 = 94.9 nM
|
|
|
| 4 |
Ki = 42 nM
|
|
|
|
CP0305824
|
N-[7-[acetyl(ethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-1-[3-(trifluoromethyl)phenyl]sulfonylpiperidine-4-carboxamide
Show/Hide
|
C25H27F3N4O5S2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0383482
|
N-(2-methyl-6-phenylpyrazolo[3,4-d]pyrimidin-4-yl)benzamide
Show/Hide
|
C19H15N5O
|
1
|
| 1 |
IC50 = 49.8 nM
|
|
|
|
CP0437628
|
1,3-dipropyl-8-[3-[[6-(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]-1,2-oxazol-5-yl]-7H-purine-2,6-dione
Show/Hide
|
C23H22F3N7O4
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0437642
|
8-[5-[(5,6-dimethyl-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C25H30N8O3
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0376874
|
4-methoxy-N-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)benzamide
Show/Hide
|
C20H17N5O2
|
1
|
| 1 |
IC50 = 53.9 nM
|
|
|
|
CP0391929
|
8-[5-[(6-methoxy-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C24H28N8O4
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0399821
|
10-Benzyl-3-phenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
|
C22H16N4O
|
1
|
| 1 |
IC50 = 54.3 nM
|
|
|
|
CP0440938
|
2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-phenylacetamide
Show/Hide
|
C23H27N7O3
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0416455
|
10-methyl-3-phenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
|
C16H12N4O
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0340022
|
4-[4-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperazin-1-yl]benzenesulfonamide
Show/Hide
|
C19H19N7O3S2
|
2
|
| 1 |
IC50 = 58 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0376494
|
N-(3,4-dichlorophenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
|
C23H25Cl2N7O4
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0371893
|
N-[7-[acetyl-(2-amino-2-oxoethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-fluorobenzamide
Show/Hide
|
C19H17FN4O4S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0437627
|
8-[2-methyl-5-[(4-methyl-1H-benzimidazol-2-yl)methoxy]pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C24H28N8O3
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0044275
|
9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine
Show/Hide
|
C13H8ClN5O
|
4
|
| 1 |
IC50 = 60.7 nM
|
|
|
| 2 |
IC50 = 1200 nM
|
|
|
| 3 |
Ki = 23 nM
|
|
|
| 4 |
Ki = 30 nM
|
|
|
|
CP0399756
|
2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-methoxyphenyl)acetamide
Show/Hide
|
C24H29N7O4
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0403606
|
8-[5-[(6-bromo-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C23H25BrN8O3
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0462151
|
8-[2-methyl-5-[(6-nitro-1H-benzimidazol-2-yl)methoxy]pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C23H25N9O5
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0403601
|
8-[3-[[4-chloro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C23H21ClF3N7O4
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0403615
|
8-[5-(1H-benzimidazol-2-ylmethoxy)-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C23H26N8O3
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0415983
|
3-ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4-dione
Show/Hide
|
C18H22F3N3O4S
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0373435
|
2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-fluorophenyl)acetamide
Show/Hide
|
C23H26FN7O3
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0387791
|
8-[5-[[4,6-bis(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C25H24F6N8O3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0534208
|
(R)-N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-1-(3-(trifluoromethyl)benzyl)pyrrolidine-3-carboxamide
Show/Hide
|
C25H27F3N4O3S
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0437629
|
8-[3-(1H-benzimidazol-2-ylmethoxy)-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C22H23N7O4
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0375425
|
2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-N-p-tolyl-acetamide
Show/Hide
|
C24H29N7O4
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0476932
|
2-(furan-2-yl)-5-N-(thiophen-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C14H11N5OS2
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0377194
|
4-fluoro-N-(7-(N-(2-hydroxyethyl)acetamido)-4-methoxybenzo[d]thiazol-2-yl)benzamide
Show/Hide
|
C19H18FN3O4S
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0373433
|
N-(4-chlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)pyrazol-1-yl]acetamide
Show/Hide
|
C22H24ClN7O3
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0403599
|
8-[5-(1H-benzo[f]benzimidazol-2-ylmethoxy)-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C27H28N8O3
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0895197
|
8-{2-Methyl-5-[2-oxo-2-(4-phenyl-piperazin-1-yl)-ethoxy]-2H-pyrazol-3-yl}-1,3-bis-((E)-propenyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
|
C27H30N8O4
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0389060
|
2-(furan-2-yl)-5-N-(furan-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C14H11N5O2S
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0380156
|
2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-N-(4-fluoro-phenyl)-acetamide
Show/Hide
|
C23H26FN7O4
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0401401
|
4-(furan-2-yl)-11-propyl-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C14H14N6O
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0411544
|
2-(5-methylfuran-2-yl)-5-N-(thiophen-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H13N5OS2
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0375834
|
N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-[4-[[2-(trifluoromethyl)phenyl]methoxy]phenyl]acetamide
Show/Hide
|
C31H32F3N7O4
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0487097
|
2-Benzo[1,3]dioxol-5-yl-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-acetamide
Show/Hide
|
C24H27N7O5
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0437630
|
8-[5-[(6-fluoro-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C23H25FN8O3
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0510734
|
5-N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C19H19N5O3S
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0411541
|
2-(furan-2-yl)-5-N-(pyridin-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H12N6OS
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0429027
|
N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-phenylacetamide
Show/Hide
|
C23H27N7O3
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0446617
|
5-N-[(3-fluorophenyl)methyl]-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C16H12FN5OS
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0373439
|
N-(3-chlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
|
C23H26ClN7O3
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0430224
|
N-(4-bromophenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
|
C23H26BrN7O4
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0909022
|
2-(Furan-2-yl)-N5-(pyridin-3-yl-methyl)[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H12N6OS
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0069170
|
N-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-naphthalen-1-ylacetamide
Show/Hide
|
C31H25N7O2
|
2
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0402920
|
2-[[7-amino-5-(furan-2-yl)pyrazolo[4,3-d]pyrimidin-2-yl]methyl]phenol
Show/Hide
|
C16H13N5O2
|
1
|
| 1 |
IC50 = 112 nM
|
|
|
|
CP0389062
|
2-(furan-2-yl)-5-N-(2-thiophen-2-ylethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H13N5OS2
|
1
|
| 1 |
IC50 = 112 nM
|
|
|
|
CP0387798
|
8-[3-[(6-methoxy-1H-benzimidazol-2-yl)methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C23H25N7O5
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
|
CP0373440
|
2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-iodophenyl)acetamide
Show/Hide
|
C23H26IN7O3
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0430510
|
4-{2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-acetylamino}-benzoic acid
Show/Hide
|
C24H27N7O6
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0373438
|
2-(3,4-Dimethoxy-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-acetamide
Show/Hide
|
C25H31N7O5
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0374684
|
4-{2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-acetylamino}-benzoic acid ethyl ester
Show/Hide
|
C26H31N7O6
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0426317
|
2-(furan-2-yl)pyrazolo[1,5-c]quinazolin-5-amine
Show/Hide
|
C14H10N4O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0411537
|
5-N-[(3-methoxyphenyl)methyl]-2-(5-methylfuran-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C18H17N5O2S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0427816
|
1-[11-(furan-2-yl)-3-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
|
C19H16N8O3
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0396875
|
5-[(2-fluorophenyl)methyl]-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
|
C18H14FN5
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0423138
|
2-(4-Chloro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-acetamide
Show/Hide
|
C23H26ClN7O3
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0397573
|
N-[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenoxyacetamide
Show/Hide
|
C26H21N7O3
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0411328
|
N-benzyl-2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]acetamide
Show/Hide
|
C23H23N5O4
|
2
|
| 1 |
IC50 = 135 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0377526
|
N-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenoxyacetamide
Show/Hide
|
C27H23N7O3
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0430550
|
N-(1,3-benzodioxol-5-yl)-2-[[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1,2-oxazol-3-yl]oxy]acetamide
Show/Hide
|
C23H24N6O7
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0520822
|
2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]-N-(2-phenylethyl)acetamide
Show/Hide
|
C24H25N5O4
|
2
|
| 1 |
IC50 = 141 nM
|
|
|
| 2 |
Ki = 7.45 nM
|
|
|
|
CP0525979
|
2-[4-[[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]methyl]piperidin-1-yl]-N-[(4-sulfamoylphenyl)methyl]acetamide
Show/Hide
|
C24H28N8O4S2
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0448140
|
N-[4-(furan-2-yl)-11-(3-methylbutyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenoxyacetamide
Show/Hide
|
C23H23N7O3
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0429028
|
N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-2-methylpyrazol-3-yl]-2-phenylacetamide
Show/Hide
|
C23H27N7O3
|
1
|
| 1 |
IC50 = 152 nM
|
|
|
|
CP0407419
|
2-[(2-chlorophenyl)methyl]-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
|
C17H14ClN5O
|
1
|
| 1 |
IC50 = 152 nM
|
|
|
|
CP0435133
|
N-(4-bromophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
|
C23H26BrN7O3
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0516849
|
2-[4-[[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]methyl]piperidin-1-yl]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
Show/Hide
|
C25H30N8O4S2
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0402119
|
N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(3-fluorophenyl)acetamide
Show/Hide
|
C23H26FN7O3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0453144
|
N-[4-(furan-2-yl)-11-(3-methylbutyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-naphthalen-1-ylacetamide
Show/Hide
|
C27H25N7O2
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0545836
|
2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]-N-(3-phenylpropyl)acetamide
Show/Hide
|
C25H27N5O4
|
2
|
| 1 |
IC50 = 174 nM
|
|
|
| 2 |
Ki = 27.9 nM
|
|
|
|
CP0454450
|
N-[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-naphthalen-1-ylacetamide
Show/Hide
|
C30H23N7O2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0387788
|
8-[2-methyl-5-[(4-oxo-3H-quinazolin-2-yl)methoxy]pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C24H26N8O4
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0455691
|
N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(4-phenylmethoxyphenyl)acetamide
Show/Hide
|
C30H33N7O4
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0471139
|
5-N-butyl-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C13H15N5OS
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0382371
|
N-(3,4-dichlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
|
C23H25Cl2N7O3
|
1
|
| 1 |
IC50 = 188 nM
|
|
|
|
CP0392343
|
N-[4-(furan-2-yl)-11-(3-methylbutyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C23H23N7O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0462138
|
8-[3-[[4,6-bis(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C24H21F6N7O4
|
1
|
| 1 |
IC50 = 197 nM
|
|
|
|
CP0399759
|
N-(3,4-dimethylphenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
|
C25H31N7O3
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0431005
|
N-[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C26H21N7O2
|
2
|
| 1 |
IC50 = 210 nM
|
|
|
| 2 |
IC50 > 3000 nM
|
|
|
|
CP0378549
|
2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-methylphenyl)acetamide
Show/Hide
|
C24H29N7O3
|
1
|
| 1 |
IC50 = 212 nM
|
|
|
|
CP0418733
|
8-[5-[[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
|
C25H28N8O5
|
1
|
| 1 |
IC50 = 219 nM
|
|
|
|
CP0403603
|
2-[[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxymethyl]-3H-benzimidazole-5-carboxylic acid
Show/Hide
|
C24H26N8O5
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0435132
|
N-(3,4-dimethoxyphenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
|
C25H31N7O5
|
1
|
| 1 |
IC50 = 222 nM
|
|
|
|
CP0377191
|
N-[7-[acetyl(difluoromethyl)amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-fluorobenzamide
Show/Hide
|
C18H14F3N3O3S
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0437643
|
N-(1,3-benzodioxol-5-yl)-2-[5-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
|
C25H28N6O6
|
1
|
| 1 |
IC50 = 236 nM
|
|
|
|
CP0853216
|
3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]-N-methylpyridinium iodide
Show/Hide
|
C18H16IN9O2
|
1
|
| 1 |
IC50 = 244 nM
|
|
|
|
CP0490037
|
2-[3-(7-amino-2-phenylpyrazolo[4,3-d]pyrimidin-5-yl)propyl]phenol
Show/Hide
|
C20H19N5O
|
1
|
| 1 |
IC50 = 247 nM
|
|
|
|
CP0475229
|
5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C20H14N8O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0395252
|
N-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C27H23N7O2
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0395752
|
4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C20H18N6O
|
1
|
| 1 |
IC50 = 251 nM
|
|
|
|
CP0382463
|
3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]pyridinium N-oxide
Show/Hide
|
C17H13N9O3
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0391881
|
N-[2-(2,2-difluoro-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-8-yl)ethyl]-2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]acetamide
Show/Hide
|
C31H34BF2N7O4
|
2
|
| 1 |
IC50 = 262 nM
|
|
|
| 2 |
Ki = 1.83 nM
|
|
|
|
CP0399758
|
2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(3-methoxyphenyl)acetamide
Show/Hide
|
C24H29N7O4
|
1
|
| 1 |
IC50 = 266 nM
|
|
|
|
CP0228719
|
4-Amino-N-(9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-butyramide
Show/Hide
|
C17H15ClN6O2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0401452
|
N-(2-benzyl-6-phenylpyrazolo[3,4-d]pyrimidin-4-yl)benzamide
Show/Hide
|
C25H19N5O
|
1
|
| 1 |
IC50 = 272 nM
|
|
|
|
CP0849513
|
2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]-N-methylpyridinium iodide
Show/Hide
|
C18H16IN9O2
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0415416
|
2-(furan-2-yl)-5-N-[(4-methoxyphenyl)methyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C17H15N5O2S
|
1
|
| 1 |
IC50 = 283 nM
|
|
|
|
CP0379859
|
2-[(3-methoxyphenyl)methyl]-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
|
C18H17N5O2
|
1
|
| 1 |
IC50 = 293 nM
|
|
|
|
CP0415421
|
2-(furan-2-yl)-5-N-[(2-methoxyphenyl)methyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
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C17H15N5O2S
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1
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| 1 |
IC50 = 313 nM
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CP0396890
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3-[3-(7-amino-2-phenylpyrazolo[4,3-d]pyrimidin-5-yl)propyl]phenol
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C20H19N5O
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1
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| 1 |
IC50 = 314 nM
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CP0452389
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11-(furan-2-yl)-3-(2-phenylethyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-amine
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C18H15N7O
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1
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| 1 |
IC50 = 319 nM
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CP0382462
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2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]pyridinium N-oxide
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C17H13N9O3
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1
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| 1 |
IC50 = 320 nM
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CP0382856
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5-methyl-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
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C12H11N5
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1
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| 1 |
IC50 = 320 nM
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CP0375426
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8-{2-Methyl-5-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethoxy]-2H-pyrazol-3-yl}-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
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C22H32N8O4
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1
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| 1 |
IC50 = 322 nM
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CP0446614
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2-(furan-2-yl)-5-N-propyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C12H13N5OS
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1
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| 1 |
IC50 = 323 nM
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CP0452832
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5-[3-(3-methoxyphenyl)propyl]-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
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C21H21N5O
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1
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| 1 |
IC50 = 334 nM
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CP0525976
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ethyl 4-[4-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperazin-1-yl]benzoate
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C22H22N6O3S
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2
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| 1 |
IC50 = 334 nM
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| 2 |
IC50 > 10000 nM
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CP0281180
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N-(7-acetamido-4-methoxy-1,3-benzothiazol-2-yl)-4-fluorobenzamide
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C17H14FN3O3S
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2
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| 1 |
IC50 = 350 nM
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| 2 |
Ki = 130 nM
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CP0438988
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4-fluoro-N-(4-methoxy-7-(N-(2-(methylamino)-2-oxoethyl)acetamido)benzo[d]thiazol-2-yl)benzamide
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C20H19FN4O4S
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1
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| 1 |
IC50 = 350 nM
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CP0402918
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2-[(2-fluorophenyl)methyl]-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
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C17H14FN5O
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1
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| 1 |
IC50 = 354 nM
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CP0387485
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5-[(Diphenylmethyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
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C25H19N7O2
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1
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| 1 |
IC50 = 363 nM
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CP0490036
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5-[3-(2-methoxyphenyl)propyl]-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
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C21H21N5O
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1
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| 1 |
IC50 = 387 nM
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CP0446615
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2-(furan-2-yl)-5-N-(2-phenylethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C17H15N5OS
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1
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| 1 |
IC50 = 389 nM
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CP0411545
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5-N-[(2-methoxyphenyl)methyl]-2-(5-methylfuran-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C18H17N5O2S
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1
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| 1 |
IC50 = 389 nM
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CP0409656
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2-[[7-amino-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-2-yl]methyl]phenol
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C17H15N5O2
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1
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| 1 |
IC50 = 395 nM
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CP0435571
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1-Benzyl-7-methyl-3-propyl-1H,6H-pyrrolo[2,1-f]purine-2,4-dione
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C19H20N4O2
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1
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| 1 |
IC50 = 400 nM
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CP0382857
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5-benzyl-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
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C18H15N5
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1
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| 1 |
IC50 = 420 nM
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CP0448053
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2-[(3-fluorophenyl)methyl]-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
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C17H14FN5O
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1
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| 1 |
IC50 = 421 nM
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CP0375235
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2-phenyl-5-(3-phenylpropyl)pyrazolo[4,3-d]pyrimidin-7-amine
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C20H19N5
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1
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| 1 |
IC50 = 432 nM
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CP0382860
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2,5-diphenylpyrazolo[4,3-d]pyrimidin-7-amine
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C17H13N5
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1
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| 1 |
IC50 = 440 nM
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CP0415414
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2-(furan-2-yl)-5-N-[(3-methoxyphenyl)methyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
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C17H15N5O2S
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1
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| 1 |
IC50 = 452 nM
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CP0459866
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2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-pyridin-2-yloxy]-N-(4-iodo-phenyl)-acetamide
Show/Hide
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C24H25IN6O4
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1
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| 1 |
IC50 = 477 nM
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CP0451426
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4-[2-[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]phenol
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C17H15N5O2S
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1
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| 1 |
IC50 = 482 nM
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CP0447917
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5-[(Diphenylmethyl)carbonyl]amino-8-n-propyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
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C27H23N7O2
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1
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| 1 |
IC50 = 491 nM
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CP0399757
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N-[(4-chlorophenyl)methyl]-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
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C25H25ClN10O3
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1
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| 1 |
IC50 = 505 nM
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CP0399160
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5-(furan-2-yl)-2-[(2-methoxyphenyl)methyl]pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C17H15N5O2
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1
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| 1 |
IC50 = 512 nM
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CP0389061
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2-thiophen-2-yl-5-N-(thiophen-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
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C14H11N5S3
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1
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| 1 |
IC50 = 547 nM
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CP0427815
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1-[11-(furan-2-yl)-4-(2-phenylethyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C26H22N8O3
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1
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| 1 |
IC50 = 548 nM
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CP0415417
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2-(furan-2-yl)-5-N-[2-(4-methoxyphenyl)ethyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C18H17N5O2S
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1
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| 1 |
IC50 = 553 nM
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CP0427817
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1-[11-(furan-2-yl)-4-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C19H16N8O3
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1
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| 1 |
IC50 = 580 nM
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CP0385419
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11-(furan-2-yl)-3-(3-phenylpropyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-amine
Show/Hide
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C19H17N7O
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1
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| 1 |
IC50 = 595 nM
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CP0439006
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N-[7-[acetyl-[2-(dimethylamino)-2-oxoethyl]amino]-4-methoxy-1,3-benzothiazol-2-yl]-4-fluorobenzamide
Show/Hide
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C21H21FN4O4S
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1
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| 1 |
IC50 = 600 nM
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CP0419545
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2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
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C11H9N5
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1
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| 1 |
IC50 = 630 nM
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CP0415413
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2-(furan-2-yl)-5-N-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C15H11N5OS
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1
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| 1 |
IC50 = 632 nM
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CP0448052
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3-[[7-amino-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-2-yl]methyl]phenol
Show/Hide
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C17H15N5O2
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1
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| 1 |
IC50 = 633 nM
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CP0428651
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1-[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C27H23N7O3
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1
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| 1 |
IC50 = 740 nM
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CP0401400
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1-[11-(furan-2-yl)-3-(2-phenylethyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C26H22N8O3
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1
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| 1 |
IC50 = 772 nM
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CP0431114
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5-[(Diphenylmethyl)carbonyl]amino-8-n-butyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C28H25N7O2
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1
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| 1 |
IC50 = 780 nM
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CP0441293
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C20H17N7O3
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1
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| 1 |
IC50 = 838 nM
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CP0395750
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1-[11-(furan-2-yl)-4-propyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C21H20N8O3
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1
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| 1 |
IC50 = 863 nM
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CP0430143
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5-[(3-Thienylmethyl)carbonyl]amino-8-n-butyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C20H19N7O2S
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1
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| 1 |
IC50 = 906 nM
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CP0395753
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1-[4-(furan-2-yl)-11-propyl-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C22H21N7O3
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1
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| 1 |
IC50 = 906 nM
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CP0463047
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N-cyclohexyl-11-(furan-2-yl)-3-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-amine
Show/Hide
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C17H19N7O
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1
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| 1 |
IC50 = 915 nM
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CP0445372
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N-[(4-fluorophenyl)methyl]-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
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C25H25FN10O3
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1
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| 1 |
IC50 = 1042 nM
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CP0410320
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N-benzyl-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
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C25H26N10O3
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1
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| 1 |
IC50 = 1107 nM
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CP0401469
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5-[(4-Chlorobenzyl)carbonyl]amino-8-isopentyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C23H22ClN7O2
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1
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| 1 |
IC50 = 1220 nM
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CP0386423
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1-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-phenylurea
Show/Hide
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C25H20N6O
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1
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| 1 |
IC50 = 1324 nM
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CP0421995
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N-(2-benzyl-6-phenylpyrazolo[3,4-d]pyrimidin-4-yl)-3-chlorobenzamide
Show/Hide
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C25H18ClN5O
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1
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| 1 |
IC50 = 1327 nM
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CP0401528
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5-[(3-Chlorobenzyl)carbonyl]amino-8-isopentyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C23H22ClN7O2
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1
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| 1 |
IC50 = 1390 nM
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CP0387468
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5-[(2,6-Dichlorobenzyl)carbonyl]amino-8-isopentyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C23H21Cl2N7O2
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1
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| 1 |
IC50 = 1440 nM
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CP0383489
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1-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-(4-methoxyphenyl)urea
Show/Hide
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C26H22N6O2
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1
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| 1 |
IC50 = 1467 nM
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CP0424321
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4-methoxy-N-(1-oxo-2-p-tolyl-1H-3,3,5,9b-tetraaza-cyclopenta[a]naphthalen-4-yl)-benzamide
Show/Hide
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C24H19N5O3
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1
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| 1 |
IC50 = 1527 nM
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CP0445369
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]-N-(3-phenylpropyl)piperidine-1-carboxamide
Show/Hide
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C27H30N10O3
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1
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| 1 |
IC50 = 1542 nM
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CP0415672
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]-N-(2-phenylethyl)piperidine-1-carboxamide
Show/Hide
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C26H28N10O3
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1
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| 1 |
IC50 = 1755 nM
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CP0446613
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2-(furan-2-yl)-5-N-(3-phenylpropyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C18H17N5OS
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1
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| 1 |
IC50 = 1768 nM
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CP0505895
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5-Amino-pentanoic acid (9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-amide
Show/Hide
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C18H17ClN6O2
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1
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| 1 |
IC50 = 1770 nM
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CP0397205
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5-[(2-Thienylmethyl)carbonyl]amino-8-n-butyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C20H19N7O2S
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1
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| 1 |
IC50 = 1810 nM
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CP0175598
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4-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylcarbamoyl)-butyric acid
Show/Hide
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C18H14ClN5O4
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1
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| 1 |
IC50 = 1900 nM
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CP0398648
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1-(1-benzylpiperidin-4-yl)-3-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C24H25N9O2
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1
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| 1 |
IC50 = 2061 nM
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CP0410321
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]-N-[(4-methylphenyl)methyl]piperidine-1-carboxamide
Show/Hide
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C26H28N10O3
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1
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| 1 |
IC50 = 2122 nM
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CP0904770
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4-[({[2-(2-Furyl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl]amino}carbonyl)amino]-N-(4-methylpiperazin-1-yl)piperidine-1-carboxamide Trifluoroacetate
Show/Hide
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C25H30F3N11O5
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1
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| 1 |
IC50 = 2144 nM
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CP0468152
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5-N-benzyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C15H13N7O
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1
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| 1 |
IC50 = 2214 nM
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CP0374164
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N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-2,2-dimethylpropanamide
Show/Hide
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C18H16ClN5O2
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1
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| 1 |
IC50 = 2400 nM
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CP0403839
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(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-carbamic acid tert-butyl ester
Show/Hide
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C18H16ClN5O3
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1
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| 1 |
IC50 = 2410 nM
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CP0445371
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-piperidin-4-ylurea
Show/Hide
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C17H19N9O2
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1
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| 1 |
IC50 = 2428 nM
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CP0448307
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N-[9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-yl]acetamide
Show/Hide
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C15H10ClN5O2
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1
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| 1 |
IC50 = 2650 nM
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CP0482181
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5-N-[(3-methoxyphenyl)methyl]-2-thiophen-2-yl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C17H15N5OS2
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1
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| 1 |
IC50 = 2773 nM
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CP0378165
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3-furan-2-yl-10-phenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
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C19H12N4O2
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1
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| 1 |
IC50 = 3200 nM
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CP0877808
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4-[({[2-(2-Furyl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl]amino}carbonyl)amino]-N-pyridin-4-ylpiperidine-1-carboxamide Trifluoroacetate
Show/Hide
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C25H24F3N11O5
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1
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| 1 |
IC50 = 3235 nM
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CP0445370
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]-N-[(4-methoxyphenyl)methyl]piperidine-1-carboxamide
Show/Hide
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C26H28N10O4
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1
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| 1 |
IC50 = 3244 nM
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CP0385357
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1-[5-(benzylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-3-phenylurea
Show/Hide
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C22H18N8O2
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1
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| 1 |
IC50 = 4360 nM
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CP0408078
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5-N-[(2-methoxyphenyl)methyl]-2-thiophen-2-yl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
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C17H15N5OS2
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1
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| 1 |
IC50 = 4571 nM
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CP0431113
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2-(4-fluorophenyl)-N-(2-(furan-2-yl)-8-isopentyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)acetamide
Show/Hide
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C23H22FN7O2
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1
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| 1 |
IC50 = 5060 nM
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CP0459195
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5-[(beta-Naphthylmethyl)carbonyl]amino-8-n-propyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C25H21N7O2
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1
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| 1 |
IC50 = 5370 nM
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CP0418636
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5-[(4-Trifluorobenzyl)carbonyl]amino-8-isopentyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C24H22F3N7O2
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1
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| 1 |
IC50 = 5480 nM
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CP0387482
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5-[(Diphenylmethyl)carbonyl]amino-8-(2-phenylethyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C32H25N7O2
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1
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| 1 |
IC50 = 5840 nM
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CP0446639
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2-(N-(2-(4-fluorobenzamido)-4-methoxybenzo[d]thiazol-7-yl)acetamido)acetic acid
Show/Hide
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C19H16FN3O5S
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1
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| 1 |
IC50 = 6000 nM
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CP0398557
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5-[(2,6-Dichlorobenzyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine(
Show/Hide
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C19H13Cl2N7O2
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1
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| 1 |
IC50 = 6450 nM
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CP0388101
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N-[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
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C15H11N7O2
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1
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| 1 |
IC50 = 7060 nM
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CP0393643
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tert-butyl N-[[4-[[[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]methyl]cyclohexyl]methyl]carbamate
Show/Hide
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C21H30N8O3
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1
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| 1 |
IC50 = 7140 nM
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CP0439324
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5-[(alpha-Naphthylmethyl)carbonyl]amino-8-n-butyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C26H23N7O2
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1
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| 1 |
IC50 = 7370 nM
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CP0213333
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2-(4-Amino-phenyl)-N-(9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-acetamide
Show/Hide
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C21H15ClN6O2
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1
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| 1 |
IC50 = 7400 nM
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CP0468155
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N-[5-(benzylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-2-phenylacetamide
Show/Hide
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C23H19N7O2
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1
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| 1 |
IC50 = 7617 nM
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CP0424403
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7-chloro-3-(furan-2-yl)-10-phenyl-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Show/Hide
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C19H11ClN4O2
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1
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| 1 |
IC50 = 7850 nM
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CP0398555
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5-[(4-Biphenylmethyl)carbonyl]amino-8-n-butyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C28H25N7O2
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1
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| 1 |
IC50 = 8630 nM
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CP0387483
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5-[(4-Biphenylmethyl)carbonyl]amino-8-isopentyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C29H27N7O2
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1
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| 1 |
IC50 = 8960 nM
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CP0405517
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2-(3-chlorophenyl)-N-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)acetamide
Show/Hide
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C19H14ClN7O2
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1
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| 1 |
IC50 = 8960 nM
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CP0430141
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5-[(3-Chlorobenzyl)carbonyl]amino-8-(2-phenylethyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C26H20ClN7O2
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1
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| 1 |
IC50 = 9100 nM
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CP0387474
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5-[(3-Thienylmethyl)carbonyl]amino-8-ethyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C18H15N7O2S
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1
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| 1 |
IC50 = 9370 nM
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CP0387019
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3-amino-N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]propanamide
Show/Hide
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C20H19N7O2
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1
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| 1 |
IC50 = 9658 nM
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CP0394039
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2-mercaptopyrimidine analogue, 5m
Show/Hide
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C16H18ClN3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0394042
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2-mercaptopyrimidine analogue, 5p
Show/Hide
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C17H21N3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0405048
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2-mercaptopyrimidine analogue, 5r
Show/Hide
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C15H16ClN3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0405049
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2-mercaptopyrimidine analogue, 5o
Show/Hide
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C17H21N3O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0387477
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5-[(3-Thienylmethyl)carbonyl]amino-8-(2-phenyl ethyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C24H19N7O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0387484
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5-[(Diphenylmethyl)carbonyl]amino-8-isopentyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C29H27N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0398558
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2-(4-chlorophenyl)-N-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)acetamide
Show/Hide
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C27H22ClN7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0401432
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5-[(4-Biphenylmethyl)carbonyl]amino-8-n-propyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C27H23N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0401468
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5-[(4-Trifluorobenzyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C20H14F3N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0401503
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5-[(beta-Naphthylmethyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C23H17N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0401530
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2-(4-chlorophenoxy)-N-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)acetamide
Show/Hide
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C27H22ClN7O3
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1
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| 1 |
IC50 > 10000 nM
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CP0418606
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5-[(Diphenylmethyl)carbonyl]amino-8-(3-phenylpropyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C33H27N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0418627
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5-[(2-Thienylmethyl)carbonyl]amino-8-(2-phenylethyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C24H19N7O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0418692
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5-[(4-Methoxybenzyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C20H17N7O3
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1
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| 1 |
IC50 > 10000 nM
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CP0430144
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5-[(2-Thienylmethyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C17H13N7O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0430159
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5-[(2,6-Dichlorobenzyl)carbonyl]amino-8-(2-phenylpropyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C27H21Cl2N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0457763
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5-[(4-Chlorophenoxymethyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C19H14ClN7O3
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1
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| 1 |
IC50 > 10000 nM
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CP0470608
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5-[(alpha-Naphthylmethyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C23H17N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0491941
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5-[(4-Biphenylmethyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C25H19N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0504910
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5-[(beta-Naphthylmethyl)carbonyl]amino-8-isopentyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C27H25N7O2
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1
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| 1 |
IC50 > 10000 nM
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CP0385399
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tert-butyl N-[2-[2-[2-[[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethoxy]ethoxy]ethyl]carbamate
Show/Hide
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C19H28N8O5
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1
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| 1 |
IC50 > 10000 nM
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CP0385401
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5-[4-[(4-bromophenyl)methyl]piperazin-1-yl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Show/Hide
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C19H19BrN8O
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1
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| 1 |
IC50 > 10000 nM
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CP0392209
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tert-butyl 4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazine-1-carboxylate
Show/Hide
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C17H22N8O3
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1
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| 1 |
IC50 > 10000 nM
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CP0395523
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tert-butyl N-[2-[[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethyl]carbamate
Show/Hide
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C15H20N8O3
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1
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| 1 |
IC50 > 10000 nM
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CP0427802
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5-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Show/Hide
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C19H19FN8O
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1
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| 1 |
IC50 > 10000 nM
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CP0431136
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tert-butyl N-[5-[[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]pentyl]carbamate
Show/Hide
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C18H26N8O3
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1
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| 1 |
IC50 > 10000 nM
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CP0456799
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N-[2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
Show/Hide
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C21H14N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0462143
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7-amino-2-(furan-2-yl)-4H-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-one
Show/Hide
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C8H6N6O2
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1
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| 1 |
IC50 > 10000 nM
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CP0873015
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2-(2-(2-(7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethoxy)ethoxy)ethanaminium 2,2,2-trifluoroacetate
Show/Hide
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C16H21F3N8O5
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1
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| 1 |
IC50 > 10000 nM
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CP0880294
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5-(7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)pentan-1-aminium 2,2,2-trifluoroacetate
Show/Hide
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C15H19F3N8O3
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1
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| 1 |
IC50 > 10000 nM
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CP0340023
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N-[[1-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperidin-4-yl]methyl]-4-sulfamoylbenzamide
Show/Hide
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C22H23N7O4S2
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1
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| 1 |
IC50 > 10000 nM
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CP0472357
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N-[[1-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperidin-4-yl]methyl]-3-(1,1,3-trioxo-1,2-benzothiazol-2-yl)propanamide
Show/Hide
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C25H25N7O5S2
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1
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| 1 |
IC50 > 10000 nM
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CP0472358
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N-[[1-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperidin-4-yl]methyl]-3-sulfamoylbenzamide
Show/Hide
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C22H23N7O4S2
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1
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| 1 |
IC50 > 10000 nM
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CP0527116
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2-[4-[[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]methyl]piperidin-1-yl]-N-(4-sulfamoylphenyl)acetamide
Show/Hide
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C23H26N8O4S2
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1
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| 1 |
IC50 > 10000 nM
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CP0547381
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N-[[1-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperidin-4-yl]methyl]-2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetamide
Show/Hide
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C24H23N7O5S2
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1
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| 1 |
IC50 > 10000 nM
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CP0387475
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5-[(beta-Naphthylmethyl)carbonyl]amino-8-ethyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C24H19N7O2
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1
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| 1 |
IC50 = 10370 nM
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CP0873223
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(4-((7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)methyl)cyclohexyl)methanaminium 2,2,2-trifluoroacetate
Show/Hide
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C18H23F3N8O3
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1
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| 1 |
IC50 = 10700 nM
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CP0430936
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5-[(4-Biphenylmethyl)carbonyl]amino-8-(2-phenylethyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C32H25N7O2
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1
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| 1 |
IC50 = 11100 nM
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CP0395527
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2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C8H7N7O
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1
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| 1 |
IC50 = 11100 nM
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CP0385367
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5-N,7-N-dibenzyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C22H19N7O
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1
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| 1 |
IC50 = 11800 nM
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CP0430792
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5-[(alpha-Naphthylmethyl)carbonyl]amino-8-n-propyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C25H21N7O2
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1
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| 1 |
IC50 = 12400 nM
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CP0418604
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5-[(4-Fluorobenzyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C19H14FN7O2
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1
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| 1 |
IC50 = 13000 nM
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CP0182221
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3-Amino-N-(9-chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-propionamide
Show/Hide
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C16H13ClN6O2
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1
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| 1 |
IC50 = 13300 nM
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CP0483580
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5-N-cyclohexyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C14H17N7O
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1
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| 1 |
IC50 = 13422 nM
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CP0388401
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5-[(3-Thienylmethyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C17H13N7O2S
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1
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| 1 |
IC50 = 13700 nM
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CP0461211
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5-[(2-Thienylmethyl)carbonyl]amino-8-ethyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
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C18H15N7O2S
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1
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| 1 |
IC50 = 15000 nM
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CP0479030
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8-amino-2-phenyl-6-(3,4,5-trihydroxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O4
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1
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| 1 |
IC50 = 17330 nM
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CP0395760
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tert-butyl N-[3-[[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]propyl]carbamate
Show/Hide
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C16H22N8O3
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1
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| 1 |
IC50 = 20600 nM
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CP0388115
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5-(4-Benzyl-piperazin-1-yl)-2-furan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ylamine
Show/Hide
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C19H20N8O
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1
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| 1 |
IC50 > 30000 nM
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CP0395525
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5-[4-(3-Chloro-benzyl)-piperazin-1-yl]-2-furan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ylamine
Show/Hide
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C19H19ClN8O
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1
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| 1 |
IC50 > 30000 nM
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CP0395526
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1-[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-2-(4-bromophenyl)ethanone
Show/Hide
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C20H19BrN8O2
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1
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| 1 |
IC50 > 30000 nM
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CP0427799
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2-(furan-2-yl)-5-pyrrolidin-1-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Show/Hide
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C12H13N7O
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1
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| 1 |
IC50 > 30000 nM
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CP0431083
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5-[4-(4-Chloro-benzyl)-piperazin-1-yl]-2-furan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ylamine
Show/Hide
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C19H19ClN8O
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1
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| 1 |
IC50 > 30000 nM
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CP0853889
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4-(7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)piperazin-1-ium 2,2,2-trifluoroacetate
Show/Hide
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C14H15F3N8O3
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1
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| 1 |
IC50 > 30000 nM
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CP0856391
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3-(7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)propan-1-aminium 2,2,2-trifluoroacetate
Show/Hide
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C13H15F3N8O3
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1
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| 1 |
IC50 > 30000 nM
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CP0385010
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N-[2-(furan-2-yl)-5-(propan-2-ylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-2-phenylacetamide
Show/Hide
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C19H19N7O2
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1
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| 1 |
IC50 > 30000 nM
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CP0385048
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N-[2-(furan-2-yl)-5-(propan-2-ylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
Show/Hide
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C18H17N7O2
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1
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| 1 |
IC50 > 30000 nM
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CP0385356
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7-N-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-5-N-methyl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C16H14FN7O
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1
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| 1 |
IC50 > 30000 nM
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CP0385358
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N-cyclohexyl-2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Show/Hide
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C20H20N6O2
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1
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| 1 |
IC50 > 30000 nM
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CP0385368
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N-benzyl-2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Show/Hide
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C21H16N6O2
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1
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| 1 |
IC50 > 30000 nM
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CP0385863
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1-[2-(furan-2-yl)-5-(propan-2-ylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-3-phenylurea
Show/Hide
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C18H18N8O2
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1
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| 1 |
IC50 > 30000 nM
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CP0385864
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5-N-benzyl-7-N-cyclohexyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C21H23N7O
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1
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| 1 |
IC50 > 30000 nM
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CP0385866
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5-N,7-N-dicyclohexyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C20H27N7O
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1
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| 1 |
IC50 > 30000 nM
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CP0385868
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7-N-cyclohexyl-2-(furan-2-yl)-5-N-methyl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C15H19N7O
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1
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| 1 |
IC50 > 30000 nM
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CP0385869
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2-(furan-2-yl)-5-N-methyl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C9H9N7O
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1
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| 1 |
IC50 > 30000 nM
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CP0385870
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2-(furan-2-yl)-5-N-propan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C11H13N7O
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1
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| 1 |
IC50 > 30000 nM
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CP0385871
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N-[2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-2-phenylacetamide
Show/Hide
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C17H15N7O2
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1
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| 1 |
IC50 > 30000 nM
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CP0385872
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N-[5-(cyclohexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-2-phenylacetamide
Show/Hide
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C22H23N7O2
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1
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| 1 |
IC50 > 30000 nM
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CP0385874
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7-N-benzyl-2-(furan-2-yl)-5-N-propan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C18H19N7O
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1
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| 1 |
IC50 > 30000 nM
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CP0400894
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N-[2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
Show/Hide
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C16H13N7O2
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1
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| 1 |
IC50 > 30000 nM
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CP0400897
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5-N-cyclohexyl-7-N-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C21H22FN7O
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1
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| 1 |
IC50 > 30000 nM
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CP0401194
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1-[5-(cyclohexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-3-phenylurea
Show/Hide
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C21H22N8O2
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1
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| 1 |
IC50 > 30000 nM
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CP0468149
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7-N-benzyl-2-(furan-2-yl)-5-N-methyl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C16H15N7O
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1
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| 1 |
IC50 > 30000 nM
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CP0468150
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7-N-cyclohexyl-2-(furan-2-yl)-5-N-propan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C17H23N7O
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1
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| 1 |
IC50 > 30000 nM
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CP0468151
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N-[5-(benzylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
Show/Hide
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C22H17N7O2
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1
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| 1 |
IC50 > 30000 nM
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CP0468153
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N-[5-(cyclohexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
Show/Hide
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C21H21N7O2
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1
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| 1 |
IC50 > 30000 nM
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CP0468154
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N-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Show/Hide
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C21H15FN6O2
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1
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| 1 |
IC50 > 30000 nM
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CP0488973
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1-[2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-3-phenylurea
Show/Hide
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C16H14N8O2
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1
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| 1 |
IC50 > 30000 nM
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CP0493753
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5-N,7-N-bis[(4-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C22H17F2N7O
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1
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| 1 |
IC50 > 30000 nM
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CP0493754
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5-N-benzyl-7-N-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C22H18FN7O
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1
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| 1 |
IC50 > 30000 nM
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CP0432532
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6-(4-methylphenyl)-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C18H14N4O2
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1
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| 1 |
IC50 > 30000 nM
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CP0432536
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8-amino-2-phenyl-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C20H19N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0432538
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2-(4-hydroxyphenyl)-6-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C17H12N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0432539
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8-amino-6-(4-ethoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C19H17N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0447251
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8-amino-2-(4-hydroxyphenyl)-6-methyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C12H11N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0447253
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2-(4-aminophenyl)-6-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C17H13N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0447254
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8-amino-2-phenyl-6-(3-phenylmethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C24H19N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0447255
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2-(2-hydroxyphenyl)-6-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C17H12N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0447256
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6-(4-methoxyphenyl)-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C18H14N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0448649
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8-amino-2-phenyl-6-(3-prop-2-ynoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C20H15N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0448650
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8-amino-6-(3-hydroxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0448678
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2-(2-methoxyphenyl)-6-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C18H14N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0448679
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2-(4-methoxyphenyl)-6-methyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C13H12N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0448681
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8-amino-6-(4-methoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C18H15N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0448682
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8-amino-2-(4-nitrophenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H12N6O3
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1
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| 1 |
IC50 > 30000 nM
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CP0455780
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8-amino-6-(3-methoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C18H15N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0455781
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8-amino-2,6-diphenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O
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1
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| 1 |
IC50 > 30000 nM
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CP0456466
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8-amino-2-(2-hydroxyphenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0456470
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2-(4-methoxyphenyl)-6-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C18H14N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0458429
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2,6-diphenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C17H12N4O2
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1
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| 1 |
IC50 > 30000 nM
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CP0458430
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8-amino-2-phenyl-6-(4-prop-2-ynoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C20H15N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0458574
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6-(3-hydroxyphenyl)-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C17H12N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0458575
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8-amino-6-(4-methylphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C18H15N5O
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1
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| 1 |
IC50 > 30000 nM
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CP0458576
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8-amino-6-methyl-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C12H11N5O
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1
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| 1 |
IC50 > 30000 nM
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CP0458577
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8-amino-6-(4-hydroxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0460462
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8-amino-2-phenyl-6-(4-propoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C20H19N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0460463
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2-(4-hydroxyphenyl)-6-methyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C12H10N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0465147
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8-amino-2-phenyl-6-(4-phenylmethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C24H19N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0468736
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8-amino-2-(4-aminophenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H14N6O
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1
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| 1 |
IC50 > 30000 nM
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CP0471114
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8-amino-2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C13H13N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0471115
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8-amino-2-(4-methoxyphenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C18H15N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0472716
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6-(4-hydroxyphenyl)-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C17H12N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0479664
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8-amino-6-[4-(cyclobutylmethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C22H21N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0479669
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6-methyl-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C12H10N4O2
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1
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| 1 |
IC50 > 30000 nM
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CP0492103
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8-amino-6-[4-(cyclopropylmethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C21H19N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0508392
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8-amino-2-(4-hydroxyphenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0533476
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6-(3-methoxyphenyl)-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C18H14N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0557261
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8-amino-2-(2-methoxyphenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C18H15N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0387016
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8-amino-6-(3,4-dihydroxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O3
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1
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| 1 |
IC50 > 30000 nM
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CP0387017
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8-amino-6-(1,3-benzodioxol-5-yl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C18H13N5O3
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1
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| 1 |
IC50 > 30000 nM
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CP0387020
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2-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenoxy]acetamide
Show/Hide
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C19H16N6O3
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1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0387021
|
8-amino-6-(4-hydroxy-2-methoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C18H15N5O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0393992
|
8-amino-6-(3-tert-butyl-4-hydroxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C21H21N5O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0436898
|
8-amino-6-(4-hydroxy-3,5-dimethylphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C19H17N5O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0436899
|
8-amino-6-(4-aminophenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C17H14N6O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0436900
|
8-amino-6-(3,5-ditert-butyl-4-methoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C26H31N5O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0436901
|
8-amino-6-(4-methoxy-3,5-dimethylphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C20H19N5O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0436903
|
N-[2-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenoxy]ethyl]-3,5-ditert-butyl-4-hydroxybenzamide
Show/Hide
|
C34H38N6O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0436904
|
8-amino-6-(3,4-dimethoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C19H17N5O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0436905
|
8-amino-6-[4-(2-aminoethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C19H18N6O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0445898
|
8-amino-6-(2,4-dimethoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C19H17N5O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0445899
|
N-[3-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)anilino]-3-oxopropyl]-3,5-ditert-butyl-4-hydroxybenzamide
Show/Hide
|
C35H39N7O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0445903
|
N-[3-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)anilino]-3-oxopropyl]-5-(dithiolan-3-yl)pentanamide
Show/Hide
|
C28H31N7O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0450753
|
8-amino-2-phenyl-6-(3,4,5-trimethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C20H19N5O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0479028
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]prop-2-enamide
Show/Hide
|
C20H16N6O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0479029
|
2-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenoxy]acetonitrile
Show/Hide
|
C19H14N6O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0482762
|
N-[2-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenoxy]ethyl]-5-(dithiolan-3-yl)pentanamide
Show/Hide
|
C27H30N6O3S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0490059
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-5-(dithiolan-3-yl)pentanamide
Show/Hide
|
C25H26N6O2S2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0427859
|
5-(5-methylfuran-2-yl)-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C16H12N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0427860
|
[4-(7-amino-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-5-yl)phenyl]methanol
Show/Hide
|
C18H14N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0427861
|
N-(5-methyl-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)benzamide
Show/Hide
|
C19H14N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0427862
|
[3-(7-amino-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-5-yl)phenyl]methanol
Show/Hide
|
C18H14N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0427863
|
4-methoxy-N-(5-methyl-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)benzamide
Show/Hide
|
C20H16N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0427864
|
2,5-bis(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C13H8N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0427865
|
2-(furan-2-yl)-5-(3-methoxyphenyl)-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C16H12N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0427866
|
N-(2,5-diphenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)benzamide
Show/Hide
|
C24H16N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0427867
|
N-[2-(furan-2-yl)-5-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]benzamide
Show/Hide
|
C22H14N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0436060
|
3-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]benzonitrile
Show/Hide
|
C16H9N5OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0455822
|
3-(7-amino-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-5-yl)benzonitrile
Show/Hide
|
C18H11N5S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0455823
|
2-(furan-2-yl)-5-(5-methylfuran-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C14H10N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0455835
|
3-(7-amino-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-5-yl)phenol
Show/Hide
|
C17H12N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0455836
|
5-(4-methoxyphenyl)-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C18H14N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0470334
|
5-(3-methoxyphenyl)-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C18H14N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0470336
|
2,5-diphenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C17H12N4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0470345
|
2-(furan-2-yl)-5-(4-methoxyphenyl)-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C16H12N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0491669
|
2-(furan-2-yl)-5-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C15H10N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0517713
|
N-[2-(furan-2-yl)-5-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]furan-2-carboxamide
Show/Hide
|
C20H12N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0517715
|
4-chloro-N-(5-methyl-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)benzamide
Show/Hide
|
C19H13ClN4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0517718
|
[4-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]phenyl]methanol
Show/Hide
|
C16H12N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0517721
|
[3-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]phenyl]methanol
Show/Hide
|
C16H12N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0517726
|
3-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]phenol
Show/Hide
|
C15H10N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0537188
|
N-(2,5-diphenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)furan-2-carboxamide
Show/Hide
|
C22H14N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0537189
|
5-(furan-2-yl)-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C15H10N4OS
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0537190
|
5-methyl-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C12H10N4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0251309
|
8-Ethoxy-3-phenylcoumarin
Show/Hide
|
C17H14O3
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0262711
|
8-Ethoxy-3-(4'-methoxyphenyl)coumarin
Show/Hide
|
C18H16O4
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0262712
|
8-Hydroxy-3-phenylcoumarin
Show/Hide
|
C15H10O3
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0286485
|
8-methoxy-3-(4-methoxyphenyl)chromen-2-one
Show/Hide
|
C17H14O4
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0420986
|
(2-oxo-3-phenylchromen-8-yl) acetate
Show/Hide
|
C17H12O4
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0420987
|
3-(4-bromophenyl)-8-hydroxychromen-2-one
Show/Hide
|
C15H9BrO3
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0420988
|
3-(4-bromophenyl)-8-ethoxychromen-2-one
Show/Hide
|
C17H13BrO3
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0420989
|
8-methyl-3-phenylchromen-2-one
Show/Hide
|
C16H12O2
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0439927
|
8-methyl-3-(3,4,5-trihydroxyphenyl)chromen-2-one
Show/Hide
|
C16H12O5
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0439928
|
(8-acetyloxy-2-oxo-3-phenylchromen-7-yl) acetate
Show/Hide
|
C19H14O6
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0443765
|
8-methyl-3-(4-nitrophenyl)chromen-2-one
Show/Hide
|
C16H11NO4
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0455153
|
3-(3,4-dihydroxyphenyl)-8-hydroxychromen-2-one
Show/Hide
|
C15H10O5
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0455154
|
3-(2,4-dimethoxyphenyl)-8-ethoxychromen-2-one
Show/Hide
|
C19H18O5
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0470627
|
8-ethoxy-3-(4-methylphenyl)chromen-2-one
Show/Hide
|
C18H16O3
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0470628
|
8-methyl-3-(4-methylphenyl)chromen-2-one
Show/Hide
|
C17H14O2
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0475489
|
8-methyl-3-(3,4,5-trimethoxyphenyl)chromen-2-one
Show/Hide
|
C19H18O5
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0475490
|
3-(3,4-dimethoxyphenyl)-8-ethoxychromen-2-one
Show/Hide
|
C19H18O5
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0477027
|
8-ethoxy-3-(3,4,5-trimethoxyphenyl)chromen-2-one
Show/Hide
|
C20H20O6
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0477468
|
[2-acetyloxy-4-(7,8-diacetyloxy-2-oxochromen-3-yl)phenyl] acetate
Show/Hide
|
C23H18O10
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0478849
|
8-methoxy-3-(4-nitrophenyl)chromen-2-one
Show/Hide
|
C16H11NO5
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0478861
|
3-(3,4-dihydroxyphenyl)-7,8-dihydroxychromen-2-one
Show/Hide
|
C15H10O6
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0482593
|
8-ethoxy-3-(4-nitrophenyl)chromen-2-one
Show/Hide
|
C17H13NO5
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0491850
|
[2-acetyloxy-4-(8-acetyloxy-2-oxochromen-3-yl)phenyl] acetate
Show/Hide
|
C21H16O8
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0508140
|
[4-(7,8-diacetyloxy-2-oxochromen-3-yl)phenyl] acetate
Show/Hide
|
C21H16O8
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0508141
|
7,8-dihydroxy-3-phenylchromen-2-one
Show/Hide
|
C15H10O4
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0533579
|
3-(3,4-dimethoxyphenyl)-8-methylchromen-2-one
Show/Hide
|
C18H16O4
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0533580
|
7,8-dihydroxy-3-(4-hydroxyphenyl)chromen-2-one
Show/Hide
|
C15H10O5
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
Ki > 30000 nM
|
|
|
|
CP0414539
|
1-[3-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)anilino]-3-oxopropyl]piperidine-4-carboxamide
Show/Hide
|
C26H28N8O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0437652
|
8-amino-6-[4-(2-hydroxyethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C19H17N5O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0437653
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-[4-(2-hydroxyethyl)piperazin-1-yl]propanamide
Show/Hide
|
C26H30N8O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0437655
|
8-amino-2-phenyl-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C23H24N6O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0473049
|
8-amino-6-[4-(2-morpholin-4-ylethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C23H24N6O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0473050
|
8-amino-6-[4-(2,3-dihydroxypropoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C20H19N5O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0473051
|
3-[4-(aminomethyl)piperidin-1-yl]-N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]propanamide
Show/Hide
|
C26H30N8O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0473052
|
8-amino-2-phenyl-6-[4-(2-piperidin-1-ylethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C24H26N6O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0473053
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-(4-phenylpiperazin-1-yl)propanamide
Show/Hide
|
C30H30N8O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0527896
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-morpholin-4-ylpropanamide
Show/Hide
|
C24H25N7O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0530029
|
8-amino-6-[4-(2-hydroxy-3-morpholin-4-ylpropoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C24H26N6O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0538564
|
8-amino-6-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C24H27N7O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0552753
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-(4-methylpiperazin-1-yl)propanamide
Show/Hide
|
C25H28N8O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0560042
|
8-amino-6-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C25H28N6O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0562150
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-pyrrolidin-1-ylpropanamide
Show/Hide
|
C24H25N7O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0567585
|
8-amino-6-[4-(2-chloroethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C19H16ClN5O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0567607
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-piperidin-1-ylpropanamide
Show/Hide
|
C25H27N7O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0387467
|
5-[(beta-Naphthylmethyl)carbonyl]amino-8-(3-phenylpropyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C31H25N7O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0387478
|
5-[(beta-Naphthylmethyl)carbonyl]amino-8-(2-phenylethyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C30H23N7O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0387480
|
5-[(4-Chlorobenzyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C19H14ClN7O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0397361
|
5-[(4-Biphenylmethyl)carbonyl]amino-8-ethyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C26H21N7O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0401529
|
5-[(4-Fluorobenzyl)carbonyl]amino-8-(3-phenylpropyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C27H22FN7O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0418631
|
5-[(alpha-Naphthylmethyl)carbonyl]amino-8-ethyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C24H19N7O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0447313
|
5-[(3-Chlorobenzyl)carbonyl]amino-8-(3-phenylpropyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C27H22ClN7O2
|
1
|
| 1 |
IC50 = 50000 nM
|
|
|
|
CP0430793
|
5-[(4-Biphenylmethyl)carbonyl]amino-8-(3-phenylpropyl)-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C33H27N7O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0385405
|
tert-butyl N-[2-[[2-(furan-2-yl)-5-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]amino]ethyl]carbamate
Show/Hide
|
C22H33N9O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0388116
|
1-[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-2-phenylethanone
Show/Hide
|
C20H20N8O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0392155
|
1-[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-2-(4-chlorophenyl)ethanone
Show/Hide
|
C20H19ClN8O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0392824
|
methyl 4-[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-4-oxobutanoate
Show/Hide
|
C17H20N8O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0395521
|
1-[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-3,3-dimethylbutan-1-one
Show/Hide
|
C18H24N8O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0395528
|
1-[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-2,2-dichloroethanone
Show/Hide
|
C14H14Cl2N8O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0395529
|
1-[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-2,2-diphenylethanone
Show/Hide
|
C26H24N8O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0423939
|
N-[2-(furan-2-yl)-5-oxo-4H-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
Show/Hide
|
C15H10N6O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0427800
|
1-[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]pentan-1-one
Show/Hide
|
C17H22N8O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0427801
|
[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C19H18N8O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0431086
|
[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-(4-nitrophenyl)methanone
Show/Hide
|
C19H17N9O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0439986
|
1-[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-2,2-dimethylpropan-1-one
Show/Hide
|
C17H22N8O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0463076
|
[4-[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]piperazin-1-yl]-naphthalen-1-ylmethanone
Show/Hide
|
C23H20N8O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0856389
|
2,2'-(2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diyl)bis(azanediyl)diethanaminium 2,2,2-trifluoroacetate
Show/Hide
|
C16H19F6N9O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0856390
|
2-(7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethanaminium 2,2,2-trifluoroacetate
Show/Hide
|
C12H13F3N8O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0426978
|
2-(4-Chloro-phenyl)-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalene-1,4-dione
Show/Hide
|
C15H9ClN4O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0445433
|
N-[9-chloro-2-(4-methylphenyl)-1-oxotriazolo[1,2-a][1,2,4]benzotriazin-5-yl]-4-methoxybenzamide
Show/Hide
|
C24H18ClN5O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0484225
|
N-(9-chloro-1-oxo-2-phenyltriazolo[1,2-a][1,2,4]benzotriazin-5-yl)-4-methoxybenzamide
Show/Hide
|
C23H16ClN5O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0058020
|
6-amino-4-benzamido-1,2-dihydro-2-(4-methoxyphenyl)-1,2,4-triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C23H18N6O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0084499
|
N-[2-(4-methoxyphenyl)-1-oxo-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]-2,2-diphenylacetamide
Show/Hide
|
C30H23N5O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0109922
|
N-benzoyl-N-[2-(4-methoxyphenyl)-1-oxo-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]benzamide
Show/Hide
|
C30H21N5O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0286482
|
N-benzoyl-N-(1-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)benzamide
Show/Hide
|
C29H19N5O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0376341
|
1-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-pyridin-4-yl-urea
Show/Hide
|
C17H13N9O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0376622
|
5-[[(quinolin-2-yl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C21H15N9O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0382460
|
5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H14N8O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0382461
|
5-[[(5-methyl-thiophen-2-yl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H14N8O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0386629
|
5-[[(3-furyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C16H12N8O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0390570
|
4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]pyridinium N-oxide
Show/Hide
|
C17H13N9O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0390571
|
5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H13N9O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0390572
|
5-[[(2-furyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C16H12N8O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0390573
|
5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
Show/Hide
|
C17H13N9O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0847039
|
4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-ureido]-N-methylpyridinium iodide
Show/Hide
|
C18H16IN9O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0849514
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(pyridin-4-yl)urea hydrochloride
Show/Hide
|
C17H14ClN9O2
|
2
|
| 1 |
IC50 > 1000 nM
|
|
|
| 2 |
Ki = 250 nM
|
|
|
|
CP0871056
|
5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine hydrochloride
Show/Hide
|
C17H14ClN9O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0881058
|
5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine hydrochloride
Show/Hide
|
C17H14ClN9O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0374603
|
1-Benzyl-7-methyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C18H19N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0375694
|
1-Benzyl-7-cyclopropyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0375735
|
1-Benzyl-7-phenyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0375736
|
1-Benzyl-7-(4-methoxy-phenyl)-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C24H23N5O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0377977
|
1-Benzyl-7-phenyl-3-propyl-1H,6H-pyrrolo[2,1-f]purine-2,4-dione
Show/Hide
|
C24H22N4O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0377978
|
1-Benzyl-7-ethyl-3-propyl-1H,6H-pyrrolo[2,1-f]purine-2,4-dione
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0393417
|
1-Benzyl-7-ethyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0394888
|
1-Benzyl-7-tert-butyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C21H25N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402019
|
1-Benzyl-7-methyl-3-allyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C18H17N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402020
|
1-Benzyl-6,7-dimethyl-3-propyl-1H,6H-pyrrolo[2,1-f]purine-2,4-dione
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402021
|
1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402022
|
1-Benzyl-7-(4-fluoro-phenyl)-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C23H20FN5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402023
|
1,3-Dipropyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402024
|
1,3,7-Trimethyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C10H11N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402026
|
1-Benzyl-6,7-dimethyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402027
|
1-Benzyl-7-biphenyl-4-yl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C29H25N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402028
|
1,3-Dimethyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C15H13N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0402029
|
1-Benzyl-7-methyl-3-prop-2-ynyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C18H15N5O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0423157
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1-Benzyl-7-cyclohexyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
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C23H27N5O2
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1
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| 1 |
IC50 > 1000 nM
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CP0423158
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1-Benzyl-7-methyl-1H,3H,8H-imidazo[2,1-f]purine-2,4-dione
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C15H13N5O2
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1
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| 1 |
IC50 > 1000 nM
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CP0423159
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1-Benzyl-7-methyl-3-(2-hydroxy-ethyl)-1H,8Himidazo[2,1-f]purine-2,4-dione
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C17H17N5O3
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1
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| 1 |
IC50 > 1000 nM
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CP0431376
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1,3-Diisobutyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
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C21H25N5O2
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1
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| 1 |
IC50 > 1000 nM
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CP0431377
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1-Benzyl-3-(2-dimethylamino-ethyl)-7-methyl-1H,8Himidazo[2,1-f]purine-2,4-dione
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C19H22N6O2
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1
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| 1 |
IC50 > 1000 nM
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CP0431379
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(1-Benzyl-7-methyl-2,4-dioxo-1,2,4,8-tetrahydro-imidazo-[2,1-f]purin-3-yl)-acetic acid ethyl ester
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C19H19N5O4
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1
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| 1 |
IC50 > 1000 nM
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CP0439600
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1-Benzyl-7-methyl-3-(2-hydroxy-propyl)-1H,8H-imidazo-[2,1-f]purine-2,4-dione
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C18H19N5O3
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1
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| 1 |
IC50 > 1000 nM
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CP0452625
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1-Benzyl-8-ethyl-7-methyl-3-propyl-1H,8H-imidazo[2,1-f]-purine-2,4-dione
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C20H23N5O2
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1
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| 1 |
IC50 > 1000 nM
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CP0452626
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1-Benzyl-7-methyl-3-(2-oxo-propyl)-1H,8H-imidazo-[2,1-f]purine-2,4-dione
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C18H17N5O3
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1
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| 1 |
IC50 > 1000 nM
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CP0474676
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1-Benzyl-8-(2-hydroxy-1-methyl-ethyl)-7-methyl-1H,8Himidazo[2,1-f]purine-2,4-dione
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C18H19N5O3
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1
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| 1 |
IC50 > 1000 nM
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CP0474680
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1-Benzyl-8-ethyl-7-methyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
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C17H17N5O2
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1
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| 1 |
IC50 > 1000 nM
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CP0474681
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1-Benzyl-7-isopropyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
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C20H23N5O2
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1
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| 1 |
IC50 > 1000 nM
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CP0870348
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7-methyl-3-propyl-1-(pyridin-4-ylmethyl)-1H-imidazo[1,2-a]purine-2,4(3H,8H)-dione hydrochloride
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C17H19ClN6O2
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1
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| 1 |
IC50 > 1000 nM
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CP0870350
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7-methyl-3-propyl-1-(pyridin-3-ylmethyl)-1H-imidazo[1,2-a]purine-2,4(3H,8H)-dione hydrochloride
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C17H19ClN6O2
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1
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| 1 |
IC50 > 1000 nM
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CP0870380
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7-methyl-3-propyl-1-(pyridin-2-ylmethyl)-1H-imidazo[1,2-a]purine-2,4(3H,8H)-dione hydrochloride
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C17H19ClN6O2
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1
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| 1 |
IC50 > 1000 nM
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CP0374607
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2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
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C17H13N3O2
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1
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| 1 |
IC50 > 1000 nM
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CP0374608
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2-(4-Fluoro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
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C16H10FN3O
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1
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| 1 |
IC50 > 1000 nM
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CP0374610
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2-Phenyl-2H-pyrazolo[4,3-c]quinoline
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C16H11N3
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1
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| 1 |
IC50 > 1000 nM
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CP0374611
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4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline
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C17H13N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0374612
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2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-thione
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C16H11N3S
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1
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| 1 |
IC50 > 1000 nM
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CP0375688
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2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
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C16H11N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0375689
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2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
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C17H13N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0375691
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2-(4-Ethyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
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C18H15N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0375706
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Benzyl-(2-phenyl-2H-pyrazolo[4,3-c]quinolin-4-yl)-amine
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C23H18N4
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1
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| 1 |
IC50 > 1000 nM
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CP0394767
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2-(2-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
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C16H10ClN3O
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1
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| 1 |
IC50 > 1000 nM
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CP0448674
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2-(4-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
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C16H10ClN3O
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1
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| 1 |
IC50 > 1000 nM
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CP0371890
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2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-[4-(2-methylpropyl)phenyl]acetamide
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C27H35N7O3
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1
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| 1 |
IC50 > 1000 nM
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CP0373431
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2-[4-bromo-3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-chlorophenyl)acetamide
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C23H25BrClN7O3
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1
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| 1 |
IC50 > 1000 nM
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CP0373432
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2-[4-chloro-3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-chlorophenyl)acetamide
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C23H25Cl2N7O3
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1
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| 1 |
IC50 > 1000 nM
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CP0373434
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N-(4-chlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-ethylpyrazol-1-yl]acetamide
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C24H28ClN7O3
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1
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| 1 |
IC50 > 1000 nM
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CP0373436
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N-[4-(dimethylamino)phenyl]-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
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C25H32N8O3
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1
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| 1 |
IC50 > 1000 nM
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CP0440939
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2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-naphthalen-1-ylacetamide
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C27H29N7O3
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1
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| 1 |
IC50 > 1000 nM
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CP0459941
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N-(4-chlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-4-iodo-5-methylpyrazol-1-yl]acetamide
Show/Hide
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C23H25ClIN7O3
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1
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| 1 |
IC50 > 1000 nM
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CP0385420
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1-[11-(furan-2-yl)-3-(3-phenylpropyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C27H24N8O3
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1
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| 1 |
IC50 > 1000 nM
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CP0385421
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1-[11-(furan-2-yl)-4-(3-phenylpropyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C27H24N8O3
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1
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| 1 |
IC50 > 1000 nM
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CP0387990
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1-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C28H25N7O3
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1
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| 1 |
IC50 > 1000 nM
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CP0387993
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11-(furan-2-yl)-3-methyl-8-(4-phenylpiperazin-1-yl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaene
Show/Hide
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C21H20N8O
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1
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| 1 |
IC50 > 1000 nM
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CP0401404
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4-[11-(furan-2-yl)-3-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-yl]morpholine
Show/Hide
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C15H15N7O2
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1
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| 1 |
IC50 > 1000 nM
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CP0401405
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11-(furan-2-yl)-3-methyl-8-(4-methylpiperazin-1-yl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaene
Show/Hide
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C16H18N8O
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1
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| 1 |
IC50 > 1000 nM
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CP0428653
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-pyridin-4-ylurea
Show/Hide
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C18H14N8O2
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1
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| 1 |
IC50 > 1000 nM
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CP0480462
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8-[2-methyl-5-(7H-purin-8-ylmethoxy)pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C21H24N10O3
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1
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| 1 |
IC50 > 1000 nM
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CP0387747
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4-benzyl-2-(5-methoxy-2-methylpyrazol-3-yl)-8-methyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C20H21N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0387748
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(8S)-4-benzyl-2-(5-methoxy-2-methylpyrazol-3-yl)-8-methyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C20H21N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0387749
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8-ethyl-2-(2-methyl-5-phenylmethoxypyrazol-3-yl)-4-prop-2-enyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C23H25N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0387750
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4-benzyl-8-ethyl-2-(5-methoxy-2-methylpyrazol-3-yl)-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C21H23N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0459537
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(8R)-4-benzyl-2-(5-methoxy-2-methylpyrazol-3-yl)-8-methyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C20H21N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0459538
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4-benzyl-8-ethyl-2-(3-methoxy-1,2-oxazol-5-yl)-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C20H20N6O3
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1
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| 1 |
IC50 > 5000 nM
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CP0459539
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4-benzyl-2-(3-methoxy-1,2-oxazol-5-yl)-8-methyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C19H18N6O3
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1
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| 1 |
IC50 > 5000 nM
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CP0459540
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4-benzyl-2-(2,5-dimethylpyrazol-3-yl)-8-methyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C20H21N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0459541
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4-benzyl-8-ethyl-2-(2-methyl-5-phenylmethoxypyrazol-3-yl)-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C27H27N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0466058
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4-benzyl-8-methyl-2-(2-methyl-5-phenylmethoxypyrazol-3-yl)-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C26H25N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0472589
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(8R)-4-benzyl-2-(2,5-dimethylpyrazol-3-yl)-8-ethyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C21H23N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0484705
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8-methyl-2-(2-methyl-5-phenylmethoxypyrazol-3-yl)-4-prop-2-enyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C22H23N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0484708
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4-benzyl-2-(2,5-dimethylpyrazol-3-yl)-8-ethyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C21H23N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0484714
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(8S)-4-benzyl-2-(2,5-dimethylpyrazol-3-yl)-8-ethyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C21H23N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0851863
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(R)-4-Allyl-7,8-dihydro-8-methyl-2-(1,3-dimethyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0851864
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(R)-4-Allyl-8-ethyl-7,8-dihydro-2-(3-methoxy-1-methyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C17H21N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0851865
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(S)-4-Allyl-8-ethyl-7,8-dihydro-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1Himidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0851866
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(R,S)-4-Allyl-7,8-dihydro-2-(3-methoxy-1-methyl-1H-pyrazol-5-yl)-8-methyl-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0851867
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(R,S)-4-Benzyl-8-ethyl-7,8-dihydro-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C21H23N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0851868
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(R,S)-4-Benzyl-7,8-dihydro-8-methyl-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C20H21N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0851869
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(R,S)-4-Allyl-8-ethyl-7,8-dihydro-2-(3-methoxy-1-methyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C17H21N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0888367
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(R)-4-Allyl-8-ethyl-7,8-dihydro-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1Himidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0888369
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(R,S)-4-Allyl-8-ethyl-7,8-dihydro-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1Himidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C17H21N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0894368
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(R,S)-4-Allyl-8-ethyl-7,8-dihydro-2-(3-methoxyisoxazol-5-yl)-1Himidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H18N6O3
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1
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| 1 |
IC50 > 5000 nM
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CP0894369
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(R,S)-4-Allyl-7,8-dihydro-2-(3-methoxyisoxazol-5-yl)-8-methyl-1Himidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C15H16N6O3
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1
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| 1 |
IC50 > 5000 nM
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CP0894370
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(R,S)-4-Allyl-7,8-dihydro-8-methyl-2-(1,3-dimethyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0894373
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(S)-4-Allyl-7,8-dihydro-8-methyl-2-(1,3-dimethyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0894374
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(S)-4-Allyl-8-ethyl-7,8-dihydro-2-(3-methoxy-1-methyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C17H21N7O2
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1
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| 1 |
IC50 > 5000 nM
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CP0903359
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(R,S)-4-Allyl-7,8-dihydro-8-methyl-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0921109
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(R,S)-4-Allyl-8-ethyl-7,8-dihydro-2-(1,3-dimethyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C17H21N7O
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1
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| 1 |
IC50 > 5000 nM
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CP0398649
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]urea
Show/Hide
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C24H24N10O4
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0399747
|
1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-[1-(pyridin-3-ylmethyl)piperidin-4-yl]urea
Show/Hide
|
C23H24N10O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0399755
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-[1-[(4-methylphenyl)methyl]piperidin-4-yl]urea
Show/Hide
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C25H27N9O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0410153
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N-cyclopentyl-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
|
C23H28N10O3
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0410154
|
1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(1-prop-2-enylpiperidin-4-yl)urea
Show/Hide
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C20H23N9O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0410322
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N-cycloheptyl-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
|
C25H32N10O3
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0415669
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-[1-(pyridin-4-ylmethyl)piperidin-4-yl]urea
Show/Hide
|
C23H24N10O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0415670
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N-cyclohexyl-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
|
C24H30N10O3
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0415671
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]-N-propan-2-ylpiperidine-1-carboxamide
Show/Hide
|
C21H26N10O3
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0416238
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(1-prop-2-ynylpiperidin-4-yl)urea
Show/Hide
|
C20H21N9O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0423985
|
1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C18H21N9O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0424051
|
1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]urea
Show/Hide
|
C25H27N9O3
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0436047
|
1-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]-3-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
|
C24H24FN9O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0436049
|
ethyl 2-[4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidin-1-yl]acetate
Show/Hide
|
C21H25N9O4
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0436054
|
1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(1-propylpiperidin-4-yl)urea
Show/Hide
|
C20H25N9O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0436091
|
1-[1-[(4-cyanophenyl)methyl]piperidin-4-yl]-3-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
|
C25H24N10O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0445368
|
N-ethyl-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
|
C20H24N10O3
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0483179
|
1-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
|
C24H24ClN9O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0867155
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N-[1-(Cyclohexylmethyl)piperidin-4-yl]-N'-[2-(2-furyl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea hydrochloride
Show/Hide
|
C24H32ClN9O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0194534
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2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-fluorophenyl)acetamide
Show/Hide
|
C22H19FN4O4
|
1
|
| 1 |
Kd = 3.981 nM
|
|
|
|
CP0058627
|
N-(4-bromophenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)-3-methoxyphenoxy]acetamide
Show/Hide
|
C23H21BrN4O5
|
1
|
| 1 |
Kd = 5.012 nM
|
|
|
|
CP0099553
|
2-[4-(1-methyl-2,4-dioxo-3-propyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-phenylphenyl)acetamide
Show/Hide
|
C30H28N4O4
|
1
|
| 1 |
Kd = 6.31 nM
|
|
|
|
CP0109685
|
N-(4-cyanophenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
Show/Hide
|
C23H19N5O4
|
1
|
| 1 |
Kd = 6.761 nM
|
|
|
|
CP0077961
|
N-(4-bromophenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
Show/Hide
|
C22H19BrN4O4
|
1
|
| 1 |
Kd = 8.71 nM
|
|
|
|
CP0173340
|
2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-phenylacetamide
Show/Hide
|
C22H20N4O4
|
1
|
| 1 |
Kd = 10 nM
|
|
|
|
CP0420803
|
8-[4-[4-(4-bromophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25BrN6O4S
|
1
|
| 1 |
Ki = 0.0835 nM
|
|
|
|
CP0538263
|
8-[4-[4-(2-bromophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25BrN6O4S
|
1
|
| 1 |
Ki = 0.137 nM
|
|
|
|
CP0424466
|
8-[4-[4-[(3-bromophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H27BrN6O4S
|
1
|
| 1 |
Ki = 0.148 nM
|
|
|
|
CP0420801
|
8-[4-[4-[(4-bromophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H27BrN6O4S
|
1
|
| 1 |
Ki = 0.153 nM
|
|
|
|
CP0431393
|
1-Ethyl-8-(4-(4-(4-trifluoromethylbenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H25F3N6O4S
|
1
|
| 1 |
Ki = 0.157 nM
|
|
|
|
CP0428798
|
8-[4-[4-(4-iodophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25IN6O4S
|
1
|
| 1 |
Ki = 0.159 nM
|
|
|
|
CP0431958
|
8-[4-[3-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]propoxy]phenyl]-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
|
C27H31ClN6O3
|
1
|
| 1 |
Ki = 0.17 nM
|
|
|
|
CP0427937
|
8-(4-(4-(4-chlorobenzyl)piperazin-1-ylsulfonyl)phenyl)-1-ethyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C24H25ClN6O4S
|
1
|
| 1 |
Ki = 0.215 nM
|
|
|
|
CP0424470
|
8-[4-[4-(4-chloro-3-methoxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H27ClN6O5S
|
1
|
| 1 |
Ki = 0.215 nM
|
|
|
|
CP0420866
|
8-[4-[4-(3-bromophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25BrN6O4S
|
1
|
| 1 |
Ki = 0.234 nM
|
|
|
|
CP0474146
|
8-[4-[4-[(4-azidophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H27N9O4S
|
1
|
| 1 |
Ki = 0.244 nM
|
|
|
|
CP0431394
|
1-Ethyl-8-(4-(4-(3-trifluoromethylbenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H25F3N6O4S
|
1
|
| 1 |
Ki = 0.281 nM
|
|
|
|
CP0495409
|
1-Propyl-8-(4-(4-(4-trifluoromethylbenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
|
C26H27F3N6O4S
|
1
|
| 1 |
Ki = 0.303 nM
|
|
|
|
CP0444681
|
8-[4-[4-(3-chlorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25ClN6O4S
|
1
|
| 1 |
Ki = 0.342 nM
|
|
|
|
CP0420799
|
8-[4-[4-(3-chloro-4-methoxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H27ClN6O5S
|
1
|
| 1 |
Ki = 0.352 nM
|
|
|
|
CP0387534
|
8-(4-(4-(4-chlorobenzyl)piperazin-1-ylsulfonyl)phenyl)-1-propyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C25H27ClN6O4S
|
1
|
| 1 |
Ki = 0.393 nM
|
|
|
|
CP0424438
|
8-[4-[4-[(3-methylphenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C26H30N6O4S
|
1
|
| 1 |
Ki = 0.397 nM
|
|
|
|
CP0425280
|
8-[4-[4-(2-chlorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25ClN6O4S
|
1
|
| 1 |
Ki = 0.403 nM
|
|
|
|
CP0388498
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8-(4-(4-(4-Chlorophenyl)piperazine-1-sulfonyl)phenyl)-1-ethyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C23H23ClN6O4S
|
1
|
| 1 |
Ki = 0.406 nM
|
|
|
|
CP0444679
|
8-[4-[4-(4-chloro-3-hydroxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25ClN6O5S
|
1
|
| 1 |
Ki = 0.421 nM
|
|
|
|
CP0425283
|
8-[4-[4-(2-methylphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H28N6O4S
|
1
|
| 1 |
Ki = 0.432 nM
|
|
|
|
CP0377682
|
8-(4-(4-(3-Fluorobenzyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H27FN6O4S
|
1
|
| 1 |
Ki = 0.446 nM
|
|
|
|
CP0377679
|
8-(4-(4-(4-Chlorophenyl)piperazine-1-sulfonyl)phenyl)-1-prop-2-ynyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H21ClN6O4S
|
1
|
| 1 |
Ki = 0.473 nM
|
|
|
|
CP0420822
|
8-[4-[4-[(4-bromo-3-fluorophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H26BrFN6O4S
|
1
|
| 1 |
Ki = 0.473 nM
|
|
|
|
CP0427942
|
8-(4-(4-(4-Fluorobenzyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H27FN6O4S
|
1
|
| 1 |
Ki = 0.595 nM
|
|
|
|
CP0387806
|
8-(4-(4-(3-Chlorobenzyl)piperazine-1-sulfonyl)phenyl)-1-ethyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25ClN6O4S
|
1
|
| 1 |
Ki = 0.61 nM
|
|
|
|
CP0490055
|
8-[4-[4-(3-methoxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H28N6O5S
|
1
|
| 1 |
Ki = 0.616 nM
|
|
|
|
CP0444683
|
8-[4-[4-[(4-fluoro-3-methoxyphenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C26H29FN6O5S
|
1
|
| 1 |
Ki = 0.629 nM
|
|
|
|
CP0420820
|
8-[4-[4-(3-fluorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25FN6O4S
|
1
|
| 1 |
Ki = 0.632 nM
|
|
|
|
CP0420823
|
8-[4-(4-phenylpiperazin-1-yl)sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H26N6O4S
|
1
|
| 1 |
Ki = 0.643 nM
|
|
|
|
CP0424467
|
8-[4-[4-(4-fluorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25FN6O4S
|
1
|
| 1 |
Ki = 0.644 nM
|
|
|
|
CP0443526
|
1-Ethyl-8-(4-(4-(3-fluorobenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25FN6O4S
|
1
|
| 1 |
Ki = 0.695 nM
|
|
|
|
CP0424431
|
8-[4-[4-(4-methylphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H28N6O4S
|
1
|
| 1 |
Ki = 0.706 nM
|
|
|
|
CP0388100
|
1-Propyl-8-(4-(4-(3-trifluoromethylbenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
|
C26H27F3N6O4S
|
1
|
| 1 |
Ki = 0.775 nM
|
|
|
|
CP0498543
|
8-(4-(4-(3-Chlorobenzyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H27ClN6O4S
|
1
|
| 1 |
Ki = 0.782 nM
|
|
|
|
CP0417993
|
8-(4-(4-(4-Methylbenzyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C26H30N6O4S
|
1
|
| 1 |
Ki = 0.858 nM
|
|
|
|
CP0388501
|
8-(4-(4-Benzo[1,3]dioxol-5-ylmethylpiperazine-1-sulfonyl)phenyl)-1-ethyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H26N6O6S
|
1
|
| 1 |
Ki = 0.875 nM
|
|
|
|
CP0420865
|
8-[4-[4-[(3-fluoro-4-methoxyphenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C26H29FN6O5S
|
1
|
| 1 |
Ki = 0.894 nM
|
|
|
|
CP0388500
|
8-(4-(4-(4-Methoxybenzyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C26H30N6O5S
|
1
|
| 1 |
Ki = 0.944 nM
|
|
|
|
CP0380983
|
8-(4-cyclopentyloxyphenyl)-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
|
C18H20N4O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0444684
|
8-[4-[4-[(3-fluoro-5-methoxyphenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C26H29FN6O5S
|
1
|
| 1 |
Ki = 1.02 nM
|
|
|
|
CP0395280
|
8-[4-(3-imidazol-1-ylpropoxy)phenyl]-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
|
C19H20N6O3
|
1
|
| 1 |
Ki = 1.05 nM
|
|
|
|
CP0377681
|
8-(4-(4-Benzo[1,3]dioxol-5-ylmethylpiperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
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C26H28N6O6S
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1
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| 1 |
Ki = 1.06 nM
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CP0439717
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8-(4-(4-benzylpiperazin-1-ylsulfonyl)phenyl)-1-ethyl-1H-purine-2,6(3H,7H)-dione
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C24H26N6O4S
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1
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| 1 |
Ki = 1.15 nM
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CP0427209
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1-Ethyl-8-(4-(4-(4-methoxybenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
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C25H28N6O5S
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1
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| 1 |
Ki = 1.19 nM
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CP0420867
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8-[4-[4-(3-fluoro-4-methoxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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C25H27FN6O5S
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1
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| 1 |
Ki = 1.24 nM
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CP0377680
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1-Ethyl-8-(4-(4-(4-fluorobenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
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C24H25FN6O4S
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1
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| 1 |
Ki = 1.27 nM
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CP0469697
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8-[4-[4-[(3-methoxyphenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H30N6O5S
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1
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| 1 |
Ki = 1.28 nM
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CP0234416
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8-(4-(4-benzylpiperazin-1-ylsulfonyl)phenyl)-1-propyl-1H-purine-2,6(3H,7H)-dione
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C25H28N6O4S
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2
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| 1 |
Ki = 1.33 nM
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| 2 |
Ki = 3.6 nM
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CP0395279
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1,3-dimethyl-8-[4-(2-morpholin-4-ylethoxy)phenyl]-7H-purine-2,6-dione
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C19H23N5O4
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1
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| 1 |
Ki = 1.34 nM
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CP0400824
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1-Ethyl-8-(4-(4-(4-methylbenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
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C25H28N6O4S
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1
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| 1 |
Ki = 1.58 nM
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CP0446607
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4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)-N-methyl-N-(2-phenylethyl)benzenesulfonamide
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C23H25N5O4S
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1
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| 1 |
Ki = 1.69 nM
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CP0420800
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8-[4-[4-(4-chlorophenyl)piperazin-1-yl]sulfonylphenyl]-3-methyl-1-propyl-7H-purine-2,6-dione
Show/Hide
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C25H27ClN6O4S
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1
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| 1 |
Ki = 1.91 nM
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CP0420868
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8-[4-[4-(4-chloro-2-fluorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H24ClFN6O4S
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1
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| 1 |
Ki = 1.91 nM
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CP0458924
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1,3-dimethyl-8-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7H-purine-2,6-dione
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C19H23N5O3
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1
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| 1 |
Ki = 1.97 nM
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CP0388499
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8-(4-(4-(4-Methoxyphenyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H28N6O5S
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1
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| 1 |
Ki = 1.99 nM
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CP0380872
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8-[4-[2-(diethylamino)ethoxy]phenyl]-1,3-dimethyl-7H-purine-2,6-dione
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C19H25N5O3
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1
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| 1 |
Ki = 2.59 nM
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CP0465323
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N-(4-phenyl-5-pyridin-4-yl-1,3-thiazol-2-yl)furan-2-carboxamide
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C19H13N3O2S
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1
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| 1 |
Ki = 2.78 nM
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CP0398047
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(R)-N-(2-hydroxy-1-phenylethyl)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)acetamide
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C30H27N3O4S
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2
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| 1 |
Ki = 2.8 nM
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| 2 |
Ki = 6.7 nM
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CP0380982
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1,3-dimethyl-8-[4-(2-piperidin-4-ylethoxy)phenyl]-7H-purine-2,6-dione
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C20H25N5O3
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1
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| 1 |
Ki = 2.9 nM
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CP0397330
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N-(1-benzylpiperidin-4-yl)-4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)benzenesulfonamide
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C26H30N6O4S
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1
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| 1 |
Ki = 3.03 nM
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CP0423080
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8-[4-[4-(2-fluorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H25FN6O4S
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1
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| 1 |
Ki = 3.22 nM
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CP0411327
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2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]-N-(4-phenylbutyl)acetamide
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C26H29N5O4
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1
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| 1 |
Ki = 3.3 nM
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CP0420804
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8-[4-[4-(3-chloro-4-hydroxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H25ClN6O5S
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1
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| 1 |
Ki = 3.55 nM
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CP0453118
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8-[4-(phenylethylamidosulfonyl)phenyl]-1-propylxanthine
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C22H23N5O4S
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1
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| 1 |
Ki = 3.62 nM
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CP0442565
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8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine
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C21H21N5O4S
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1
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| 1 |
Ki = 4.2 nM
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CP0424433
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8-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H26N6O5S
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1
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| 1 |
Ki = 4.3 nM
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CP0420869
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8-[4-[4-(4-chlorophenyl)piperazin-1-yl]sulfonylphenyl]-3-ethyl-1-propyl-7H-purine-2,6-dione
Show/Hide
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C26H29ClN6O4S
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1
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| 1 |
Ki = 4.31 nM
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CP0403757
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8-[4-(phenylethylamidosulfonyl)phenyl]-1,3-dimethylxanthine
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C21H21N5O4S
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1
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| 1 |
Ki = 4.48 nM
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CP0374990
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2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(1-phenylcyclopropyl)acetamide
Show/Hide
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C31H27N3O3S
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2
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| 1 |
Ki = 4.5 nM
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| 2 |
Ki = 12 nM
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CP0150101
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8-Phenyl-1-propyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C14H14N4O2
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1
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| 1 |
Ki = 4.7 nM
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CP0431957
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8-[4-[2-(dimethylamino)ethoxy]phenyl]-1,3-dimethyl-7H-purine-2,6-dione
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C17H21N5O3
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1
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| 1 |
Ki = 4.95 nM
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CP0293183
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2-(furan-2-yl)-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C18H15N7O
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1
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| 1 |
Ki = 5.1 nM
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CP0447642
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2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide
Show/Hide
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C31H29N3O3S
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2
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| 1 |
Ki = 5.1 nM
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| 2 |
Ki = 28 nM
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CP0409847
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4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 4-nitro-phenyl ester
Show/Hide
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C20H17N5O7S
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1
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| 1 |
Ki = 5.4 nM
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CP0377683
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1-Ethyl-8-(4-(piperidine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
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C18H21N5O4S
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1
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| 1 |
Ki = 5.43 nM
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CP0424465
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8-[4-(4-benzoylpiperazin-1-yl)sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H26N6O5S
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1
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| 1 |
Ki = 5.69 nM
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CP0445937
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N-[5-(2,2-difluoro-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-8-yl)pentyl]-2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]acetamide
Show/Hide
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C34H40BF2N7O4
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1
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| 1 |
Ki = 5.9 nM
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CP0420805
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8-[4-[4-[4-(2-hydroxyethoxy)phenyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H30N6O6S
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1
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| 1 |
Ki = 6.08 nM
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CP0424439
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8-[4-[4-[[4-[2-(2-methoxyethoxy)ethoxy]phenyl]methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C30H38N6O7S
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1
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| 1 |
Ki = 7.02 nM
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CP0882701
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8-(4-(3-methyl-4-phenylpiperazin-1-ylsulfonyl)phenyl)-1-propyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
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C25H28N6O4S
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1
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| 1 |
Ki = 7.15 nM
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CP0386036
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(S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(1-phenylpropyl)acetamide
Show/Hide
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C31H29N3O3S
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2
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| 1 |
Ki = 7.4 nM
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| 2 |
Ki = 20 nM
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CP0443428
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1-Ethyl-8-(4-(4-phenethylpiperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H28N6O4S
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1
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| 1 |
Ki = 7.49 nM
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CP0377685
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8-(4-(4-Phenethylpiperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H30N6O4S
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1
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| 1 |
Ki = 7.51 nM
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CP0464128
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N-[10-(2,2-difluoro-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-8-yl)decyl]-2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]acetamide
Show/Hide
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C39H50BF2N7O4
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1
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| 1 |
Ki = 7.82 nM
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CP0869451
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8-(4-((4-(1-Phenylethyl)piperazin-1-yl)sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H30N6O4S
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1
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| 1 |
Ki = 8.34 nM
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CP0255917
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2-(furan-2-yl)-8-isopentyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C15H17N7O
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1
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| 1 |
Ki = 9.1 nM
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CP0521553
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N-[3-(2,2-difluoro-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-8-yl)propyl]-2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]acetamide
Show/Hide
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C32H36BF2N7O4
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1
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| 1 |
Ki = 11.6 nM
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CP0400826
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1-Ethyl-8-(4-(4-(4-methoxyphenyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H26N6O5S
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1
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| 1 |
Ki = 11.7 nM
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CP0288790
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1-Butyl-8-phenyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C15H16N4O2
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1
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| 1 |
Ki = 11.8 nM
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CP0045163
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2-(furan-2-yl)-8-(3-methylbut-2-enyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C15H15N7O
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1
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| 1 |
Ki = 12 nM
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CP0482644
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8-[4-[4-[[4-(2-hydroxyethoxy)phenyl]methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C27H32N6O6S
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1
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| 1 |
Ki = 12.2 nM
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CP0395093
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4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 3-nitro-phenyl ester
Show/Hide
|
C20H17N5O7S
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1
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| 1 |
Ki = 13 nM
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CP0398046
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(S)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(1-phenylethyl)acetamide
Show/Hide
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C30H27N3O3S
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2
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| 1 |
Ki = 15 nM
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| 2 |
Ki = 28 nM
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CP0501666
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1-((2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yl)methyl)-3-(2-phenylpropan-2-yl)urea
Show/Hide
|
C31H30N4O2S
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1
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| 1 |
Ki = 17 nM
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CP0420864
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4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)-N,N-dimethylbenzenesulfonamide
Show/Hide
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C16H19N5O4S
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1
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| 1 |
Ki = 18.6 nM
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CP0386033
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1-benzyl-3-((2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yl)methyl)urea
Show/Hide
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C29H26N4O2S
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2
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| 1 |
Ki = 19 nM
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| 2 |
Ki = 68 nM
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CP0387535
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8-(4-(Piperidine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C19H23N5O4S
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1
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| 1 |
Ki = 19.7 nM
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CP0380534
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N-benzyl-2-[[2-oxo-4-(2-phenylethyl)-3-(1,3-thiazol-2-yl)-1H-quinolin-6-yl]oxy]acetamide
Show/Hide
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C29H25N3O3S
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2
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| 1 |
Ki = 21 nM
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| 2 |
Ki = 37 nM
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CP0437409
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1-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
|
C21H15ClN6O3
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1
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| 1 |
Ki = 22 nM
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CP0377763
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4-(1-Butyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 3-nitro-phenyl ester
Show/Hide
|
C21H19N5O7S
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1
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| 1 |
Ki = 23 nM
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CP0456175
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N-[4-(2,2-difluoro-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-8-yl)butyl]-2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]acetamide
Show/Hide
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C33H38BF2N7O4
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1
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| 1 |
Ki = 24.4 nM
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CP0432797
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4-(1-Butyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 4-nitro-phenyl ester
Show/Hide
|
C21H19N5O7S
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1
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| 1 |
Ki = 26 nM
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CP0382101
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8-[4-(2-Hydroxyethylamidosulfonyl)phenyl]-1-propylxanthine
Show/Hide
|
C16H19N5O5S
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1
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| 1 |
Ki = 27.1 nM
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CP0102758
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1-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-3-(3-chloro-phenyl)-urea
Show/Hide
|
C20H12Cl2N6O2
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1
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| 1 |
Ki = 30 nM
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CP0386041
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2-(3-(3-methylisoxazol-5-yl)-2-oxo-4-phenethyl-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide
Show/Hide
|
C32H31N3O4
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1
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| 1 |
Ki = 31 nM
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CP0395378
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8-[4-(phenylamidosulfonyl)phenyl]-1-propylxanthine
Show/Hide
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C20H19N5O4S
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1
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| 1 |
Ki = 31.4 nM
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CP0437767
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2-Amino-4,6-di-furan-2-yl-nicotinonitrile
Show/Hide
|
C14H9N3O2
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1
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| 1 |
Ki = 34 nM
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CP0544077
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4-phenyl-8-(3-pyrrolidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
Ki = 36.9 nM
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CP0222480
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2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C13H13N7O
|
1
|
| 1 |
Ki = 39 nM
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CP0503027
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2-(4-(4-fluorophenethyl)-2-oxo-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide
Show/Hide
|
C31H28FN3O3S
|
2
|
| 1 |
Ki = 41 nM
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| 2 |
Ki = 105 nM
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CP0077413
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(2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C15H20ClN5O4
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1
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| 1 |
Ki = 42 nM
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CP0407263
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4-amino-6-(1,3-benzodioxol-5-yl)-2-(1,3-thiazol-4-ylmethylsulfanyl)pyrimidine-5-carbonitrile
Show/Hide
|
C16H11N5O2S2
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1
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| 1 |
Ki = 42 nM
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CP0397880
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4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 3-nitro-phenyl ester
Show/Hide
|
C23H23N5O7S
|
1
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| 1 |
Ki = 43 nM
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CP0049200
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(2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C15H21N5O4
|
1
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| 1 |
Ki = 43 nM
|
|
|
|
CP0544075
|
2-amino-4-phenyl-8-(3-piperidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
Ki = 43.5 nM
|
|
|
|
CP0562422
|
2-amino-4-phenyl-8-(3-pyrrolidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C24H24N4O2
|
1
|
| 1 |
Ki = 47.5 nM
|
|
|
|
CP0542506
|
8-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C19H24N6O4S
|
1
|
| 1 |
Ki = 48.2 nM
|
|
|
|
CP0116393
|
2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C19H17N7O
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0316241
|
2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C10H7N7O
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0045160
|
8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
|
C14H15N7O
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0374224
|
4-(1-Methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid
Show/Hide
|
C12H10N4O5S
|
1
|
| 1 |
Ki = 53.4 nM
|
|
|
|
CP0065233
|
4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid
Show/Hide
|
C14H14N4O5S
|
1
|
| 1 |
Ki = 53.4 nM
|
|
|
|
CP0376364
|
8-[4-(dipropylamidosulfonyl)phenyl]-1-propylxanthine
Show/Hide
|
C20H27N5O4S
|
1
|
| 1 |
Ki = 53.8 nM
|
|
|
|
CP0045162
|
1-(2-(furan-2-yl)-8-isopentyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C23H24N8O3
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0248931
|
1-(3-chlorophenyl)-3-[2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]urea
Show/Hide
|
C20H17ClN8O2
|
1
|
| 1 |
Ki = 57 nM
|
|
|
|
CP0264648
|
1-(2-(furan-2-yl)-8-(3-methylbut-2-enyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C23H22N8O3
|
1
|
| 1 |
Ki = 58 nM
|
|
|
|
CP0542599
|
4-phenyl-8-(3-piperidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 58.1 nM
|
|
|
|
CP0264647
|
1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-methyl-butyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea
Show/Hide
|
C22H21ClN8O2
|
1
|
| 1 |
Ki = 61 nM
|
|
|
|
CP0258378
|
8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
|
C12H11N7O
|
1
|
| 1 |
Ki = 65 nM
|
|
|
|
CP0942306
|
2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(2-(pyrrolidin-1-yl)ethyl)acetamide
Show/Hide
|
C32H47N7O4
|
1
|
| 1 |
Ki = 66.3 nM
|
|
|
|
CP0092135
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-chloro-phenyl)-urea
Show/Hide
|
C21H19ClN8O2
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0167686
|
1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C17H11ClN8O2
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0407292
|
4-(1-Butyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid
Show/Hide
|
C15H16N4O5S
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0374991
|
2-(2-oxo-4-(phenoxymethyl)-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide
Show/Hide
|
C30H27N3O4S
|
2
|
| 1 |
Ki = 70 nM
|
|
|
| 2 |
Ki = 81 nM
|
|
|
|
CP0506091
|
N-benzyl-2-[1-methyl-3-methylsulfonyl-2-oxo-4-(2-phenylethyl)quinolin-6-yl]oxyacetamide
Show/Hide
|
C28H28N2O5S
|
2
|
| 1 |
Ki = 70 nM
|
|
|
| 2 |
Ki = 352 nM
|
|
|
|
CP0373887
|
2-Amino-4-thiophen-2-yl-6-furan-2-yl-nicotinonitrile
Show/Hide
|
C14H9N3OS
|
1
|
| 1 |
Ki = 75 nM
|
|
|
|
CP0045165
|
1-(2-(furan-2-yl)-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C26H22N8O3
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0316242
|
1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-methyl-but-2-enyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea
Show/Hide
|
C22H19ClN8O2
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0278022
|
2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C11H9N7O
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0333181
|
1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C25H19ClN8O2
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0420802
|
4-[[4-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenyl]sulfonylpiperazin-1-yl]methyl]benzoic acid
Show/Hide
|
C26H28N6O6S
|
1
|
| 1 |
Ki = 96.7 nM
|
|
|
|
CP0394811
|
4-(1-propylxanthin-8-yl)phenylsulfonamidoacetic acid
Show/Hide
|
C16H17N5O6S
|
1
|
| 1 |
Ki = 101 nM
|
|
|
|
CP0403759
|
8-[4-(isopropylamidosulfonyl)phenyl]-1,3-dimethylxanthine
Show/Hide
|
C16H19N5O4S
|
1
|
| 1 |
Ki = 102 nM
|
|
|
|
CP0883749
|
2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(2-(diethylamino)ethyl)acetamide
Show/Hide
|
C32H49N7O4
|
1
|
| 1 |
Ki = 113 nM
|
|
|
|
CP0549760
|
2-amino-4-phenyl-7-(3-piperidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
Ki = 114 nM
|
|
|
|
CP0467043
|
(E)-N-(4-oxo-3,1-benzothiazin-2-yl)-4-phenylbut-3-enamide
Show/Hide
|
C18H14N2O2S
|
1
|
| 1 |
Ki = 119 nM
|
|
|
|
CP0403756
|
8-[4-(butylamidosulfonyl)phenyl]-1,3-dimethylxanthine
Show/Hide
|
C17H21N5O4S
|
1
|
| 1 |
Ki = 122 nM
|
|
|
|
CP0757606
|
2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(3-(diethylamino)propyl)acetamide
Show/Hide
|
C33H51N7O4
|
1
|
| 1 |
Ki = 126 nM
|
|
|
|
CP0420579
|
1,3-dibutyl-9-[2-(4-hydroxyphenyl)ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C24H33N5O3
|
1
|
| 1 |
Ki = 131 nM
|
|
|
|
CP0222481
|
1-(3-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C19H15ClN8O2
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0408568
|
2-(4-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)phenylsulfonamido)acetic acid
Show/Hide
|
C15H15N5O6S
|
1
|
| 1 |
Ki = 154 nM
|
|
|
|
CP0502300
|
2-Amino-6-furan-2-yl-4-phenyl-nicotinonitrile
Show/Hide
|
C16H11N3O
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0905418
|
N-(2-(diethylamino)ethyl)-2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
|
C30H45N7O4
|
1
|
| 1 |
Ki = 179 nM
|
|
|
|
CP0546060
|
2-amino-4-phenyl-7-(3-pyrrolidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C24H24N4O2
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0496617
|
2-(2-oxo-4-phenethyl-3-(pyridin-3-yl)-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide
Show/Hide
|
C33H31N3O3
|
1
|
| 1 |
Ki = 187 nM
|
|
|
|
CP0905417
|
2-(4-(2-(2,4-Dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(2-(pyrrolidin-1-yl)ethyl)-acetamide
Show/Hide
|
C30H43N7O4
|
1
|
| 1 |
Ki = 193 nM
|
|
|
|
CP0385413
|
8-Bromo-9-propyl-9H-adenine
Show/Hide
|
C8H10BrN5
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0264646
|
1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
|
C18H13ClN8O2
|
1
|
| 1 |
Ki = 205 nM
|
|
|
|
CP0399738
|
(2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3-ylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C14H18ClN5O5
|
1
|
| 1 |
Ki = 211 nM
|
|
|
|
CP0380536
|
N-[(3,4-dichlorophenyl)methyl]-2-[[3-methylsulfonyl-2-oxo-4-(2-phenylethyl)-1H-quinolin-6-yl]oxy]acetamide
Show/Hide
|
C27H24Cl2N2O5S
|
2
|
| 1 |
Ki = 211 nM
|
|
|
| 2 |
Ki = 315 nM
|
|
|
|
CP0893520
|
N-(3-(cyclohexylamino)propyl)-2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
|
C35H53N7O4
|
1
|
| 1 |
Ki = 215 nM
|
|
|
|
CP0437768
|
2-Amino-4-furan-2-yl-6-phenyl-nicotinonitrile
Show/Hide
|
C16H11N3O
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0476881
|
2-(4-amino-6-phenyl-1,3,5-triazin-2-yl)phenol
Show/Hide
|
C15H12N4O
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0273529
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-phenylurea
Show/Hide
|
C18H14N8O2
|
1
|
| 1 |
Ki = 222 nM
|
|
|
|
CP0365871
|
3-(3-methoxyphenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)propanamide
Show/Hide
|
C18H16N2O3S
|
1
|
| 1 |
Ki = 225 nM
|
|
|
|
CP0047370
|
1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea
Show/Hide
|
C26H21ClN8O2
|
1
|
| 1 |
Ki = 226 nM
|
|
|
|
CP0708191
|
TECADENOSON
Show/Hide
|
C14H19N5O5
|
1
|
| 1 |
Ki = 227 nM
|
|
|
|
CP0714869
|
sodium 4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonate
Show/Hide
|
C14H13N4NaO5S
|
1
|
| 1 |
Ki = 237 nM
|
|
|
|
CP0308558
|
1-(8-ethyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C20H18N8O3
|
1
|
| 1 |
Ki = 245 nM
|
|
|
|
CP0039790
|
4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid
Show/Hide
|
C17H20N4O5S
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0395376
|
8-[4-(2-hydroxyethylamidosulfonyl)phenyl]-1,3-dimethylxanthine
Show/Hide
|
C15H17N5O5S
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0405999
|
8-(furan-2-yl)-9-propylpurin-6-amine
Show/Hide
|
C12H13N5O
|
2
|
| 1 |
Ki = 250 nM
|
|
|
| 2 |
Ki = 252 nM
|
|
|
|
CP0282756
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C19H16N8O3
|
1
|
| 1 |
Ki = 261 nM
|
|
|
|
CP0906663
|
N-(3-(1H-imidazol-1-yl)propyl)-2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
|
C32H44N8O4
|
1
|
| 1 |
Ki = 275 nM
|
|
|
|
CP0380531
|
N-[[2-oxo-4-(2-phenylethyl)-3-(1,3-thiazol-2-yl)-1H-quinolin-6-yl]methyl]-3-phenylpropanamide
Show/Hide
|
C30H27N3O2S
|
2
|
| 1 |
Ki = 291 nM
|
|
|
| 2 |
Ki = 1926 nM
|
|
|
|
CP0883750
|
2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(2-morpholinoethyl)acetamide
Show/Hide
|
C32H47N7O5
|
1
|
| 1 |
Ki = 298 nM
|
|
|
|
CP0420744
|
4-(3-methoxyphenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)butanamide
Show/Hide
|
C19H18N2O3S
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0220980
|
1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
|
C22H22N8O3
|
1
|
| 1 |
Ki = 303 nM
|
|
|
|
CP0887576
|
N-(3-(cyclohexylamino)propyl)-2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
|
C33H49N7O4
|
1
|
| 1 |
Ki = 306 nM
|
|
|
|
CP0386039
|
(R)-2-(2-oxo-4-phenethyl-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(1-phenylethyl)acetamide
Show/Hide
|
C30H27N3O3S
|
2
|
| 1 |
Ki = 320 nM
|
|
|
| 2 |
Ki = 486 nM
|
|
|
|
CP0386032
|
N-benzyl-2-[[3-(furan-2-yl)-2-oxo-4-(2-phenylethyl)-1H-quinolin-6-yl]oxy]acetamide
Show/Hide
|
C30H26N2O4
|
2
|
| 1 |
Ki = 330 nM
|
|
|
| 2 |
Ki = 1124 nM
|
|
|
|
CP0549758
|
2-amino-4-[4-(3-piperidin-1-ylpropoxy)phenyl]indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
Ki = 331 nM
|
|
|
|
CP0381191
|
(2-anilino-4-phenyl-1,3-thiazol-5-yl)-phenylmethanone
Show/Hide
|
C22H16N2OS
|
1
|
| 1 |
Ki = 337 nM
|
|
|
|
CP0465048
|
1,3-dibutyl-9-[2-[4-(2-morpholin-4-ylethoxy)phenyl]ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C30H44N6O4
|
1
|
| 1 |
Ki = 337 nM
|
|
|
|
CP0374989
|
2-(3-cyano-2-oxo-4-phenethyl-1,2-dihydroquinolin-6-yloxy)-N-(3,4-dichlorobenzyl)acetamide
Show/Hide
|
C27H21Cl2N3O3
|
2
|
| 1 |
Ki = 338 nM
|
|
|
| 2 |
Ki = 667 nM
|
|
|
|
CP0420576
|
9-[2-[4-[2-(diethylamino)ethoxy]phenyl]ethyl]-1,3-dipropyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C28H42N6O3
|
1
|
| 1 |
Ki = 338 nM
|
|
|
|
CP0958743
|
N-(3-(diethylamino)propyl)-2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
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C31H47N7O4
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1
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| 1 |
Ki = 340 nM
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CP0045157
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1-(2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
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C18H14N8O3
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1
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| 1 |
Ki = 350 nM
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CP0406006
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3-[6-amino-8-(furan-2-yl)purin-9-yl]propan-1-ol
Show/Hide
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C12H13N5O2
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1
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| 1 |
Ki = 350 nM
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CP0303994
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N-(4-oxothieno[2,3-d][1,3]thiazin-2-yl)-4-phenylbutanamide
Show/Hide
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C16H14N2O2S2
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1
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| 1 |
Ki = 361 nM
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CP0366079
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N-(4-oxo-3,1-benzothiazin-2-yl)-3-phenylpropanamide
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C17H14N2O2S
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1
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| 1 |
Ki = 365 nM
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CP0373873
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2-Amino-4-(4-hydroxy-phenyl)-6-furan-2-yl-nicotinonitrile
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C16H11N3O2
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1
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| 1 |
Ki = 370 nM
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CP0353552
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9-ethyl-8-(furan-2-yl)purin-6-amine
Show/Hide
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C11H11N5O
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1
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| 1 |
Ki = 375 nM
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CP0381659
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2-Amino-4-furan-2-yl-6-thiophen-2-yl-nicotinonitrile
Show/Hide
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C14H9N3OS
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1
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| 1 |
Ki = 380 nM
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CP0124961
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ethyl N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)carbamate
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C19H16N2O3S
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1
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| 1 |
Ki = 391 nM
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CP0133196
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8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C14H15N7O
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1
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| 1 |
Ki = 400 nM
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CP0420743
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N-(6-methyl-4-oxo-3,1-benzothiazin-2-yl)-4-phenylbutanamide
Show/Hide
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C19H18N2O2S
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1
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| 1 |
Ki = 408 nM
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CP0388356
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2-Amino-4-(5-methyl-furan-2-yl)-6-furan-2-yl-nicotinonitrile
Show/Hide
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C15H11N3O2
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1
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| 1 |
Ki = 440 nM
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CP0139906
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1-(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-chloro-phenyl)-urea
Show/Hide
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C21H19ClN8O2
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1
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| 1 |
Ki = 450 nM
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CP0860864
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2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(3-(pyrrolidin-1-yl)propyl)acetamide
Show/Hide
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C31H45N7O4
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1
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| 1 |
Ki = 452 nM
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CP0406001
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2-[6-amino-8-(furan-2-yl)purin-9-yl]ethanol
Show/Hide
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C11H11N5O2
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1
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| 1 |
Ki = 470 nM
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CP0386040
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2-(2-oxo-4-phenethyl-3-(pyridin-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide
Show/Hide
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C33H31N3O3
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1
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| 1 |
Ki = 504 nM
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CP0420742
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N-(4-oxothieno[3,2-d][1,3]thiazin-2-yl)-4-phenylbutanamide
Show/Hide
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C16H14N2O2S2
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1
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| 1 |
Ki = 547 nM
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CP0944324
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N-benzyl-2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
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C33H42N6O4
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1
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| 1 |
Ki = 578 nM
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CP0515147
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9-phenethyl-1,3-dipropyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
Show/Hide
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C22H29N5O2
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1
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| 1 |
Ki = 590 nM
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CP0400895
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2-Amino-4-(3-methyl-phenyl)-6-furan-2-yl-nicotinonitrile
Show/Hide
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C17H13N3O
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1
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| 1 |
Ki = 620 nM
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CP0398044
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2-(3-(2,4-difluorophenyl)-1-methyl-2-oxo-4-phenethyl-1,2-dihydroquinolin-6-yloxy)-N-(3-methoxypropyl)acetamide
Show/Hide
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C30H30F2N2O4
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2
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| 1 |
Ki = 633 nM
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| 2 |
Ki = 677 nM
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CP0381892
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8-Bromo-9-(2-hydroxypropyl)-9H-adenine
Show/Hide
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C8H10BrN5O
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1
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| 1 |
Ki = 640 nM
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CP0450338
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9-[2-(4-hydroxyphenyl)ethyl]-1,3-dipropyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C22H29N5O3
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1
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| 1 |
Ki = 663 nM
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CP0420746
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(E)-3-(3-methoxyphenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)prop-2-enamide
Show/Hide
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C18H14N2O3S
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1
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| 1 |
Ki = 679 nM
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CP0374988
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N-[(3,4-dichlorophenyl)methyl]-N-methyl-2-[[3-methylsulfonyl-2-oxo-4-(2-phenylethyl)-1H-quinolin-6-yl]oxy]acetamide
Show/Hide
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C28H26Cl2N2O5S
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2
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| 1 |
Ki = 710 nM
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| 2 |
Ki = 1017 nM
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CP0381894
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8-Bromo-9-methyl-9H-adenine
Show/Hide
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C6H6BrN5
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1
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| 1 |
Ki = 720 nM
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CP0393023
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N-cyclobutyl-8-phenyl-9-propylpurin-6-amine
Show/Hide
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C18H21N5
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1
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| 1 |
Ki = 774 nM
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CP0473788
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8-(furan-2-yl)-9-methylpurin-6-amine
Show/Hide
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C10H9N5O
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1
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| 1 |
Ki = 786 nM
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CP0540372
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N-[8-(furan-2-yl)-9-methylpurin-6-yl]-2,2-diphenylacetamide
Show/Hide
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C24H19N5O2
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1
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| 1 |
Ki = 792 nM
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CP0381033
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6-cyclooctyl-2,4-dimethyl-7,8-dihydropurino[7,8-a]imidazole-1,3-dione
Show/Hide
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C17H25N5O2
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1
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| 1 |
Ki = 800 nM
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CP0375531
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3-(2-fluorophenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)propanamide
Show/Hide
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C17H13FN2O2S
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1
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| 1 |
Ki = 801 nM
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CP0250678
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1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
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C27H24N8O3
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1
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| 1 |
Ki = 802 nM
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CP0406008
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8-Bromo-9-ethyl-9H-adenine
Show/Hide
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C7H8BrN5
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1
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| 1 |
Ki = 840 nM
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CP0396621
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N-(4-phenyl-5-pyridin-2-yl-1,3-thiazol-2-yl)furan-2-carboxamide
Show/Hide
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C19H13N3O2S
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1
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| 1 |
Ki = 841 nM
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CP0424776
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9-[2-[4-(2-morpholin-4-ylethoxy)phenyl]ethyl]-1,3-dipropyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C28H40N6O4
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1
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| 1 |
Ki = 853 nM
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CP0381890
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8-Bromo-9-cyclopentyl-9H-adenine
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C10H12BrN5
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1
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| 1 |
Ki = 860 nM
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CP0928977
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N-(3-(1H-imidazol-1-yl)propyl)-2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
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C30H40N8O4
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1
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| 1 |
Ki = 862 nM
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CP0421843
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(2R,3R,4R,5R)-2-(6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol
Show/Hide
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C16H23N5O4
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1
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| 1 |
Ki = 879 nM
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CP0380532
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2-(2-oxo-4-phenethyl-3-(pyridin-4-yl)-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide
Show/Hide
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C33H31N3O3
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1
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| 1 |
Ki = 884 nM
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CP0928976
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2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(2-morpholinoethyl)acetamide
Show/Hide
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C30H43N7O5
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1
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| 1 |
Ki = 911 nM
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CP0391519
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(3-methoxyphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H17N5O4
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1
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| 1 |
Ki = 1000 nM
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CP0478877
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8-phenyl-9-propylpurin-6-amine
Show/Hide
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C14H15N5
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1
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| 1 |
Ki = 1040 nM
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CP0399761
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8-Bromo-9-isopropyl-9H-adenine
Show/Hide
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C8H10BrN5
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1
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| 1 |
Ki = 1100 nM
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CP0381328
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N-cyclobutyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C15H15N7O
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1
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| 1 |
Ki = 1110 nM
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CP0380882
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ethyl 5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C12H11N5O3
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1
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| 1 |
Ki = 1110 nM
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CP0079479
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2-Furan-2-yl-8-(2,4,5-tribromo-benzyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C18H12Br3N7O
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1
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| 1 |
Ki = 1113 nM
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CP0428385
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(2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol
Show/Hide
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C16H22ClN5O4
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1
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| 1 |
Ki = 1150 nM
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CP0396834
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2-(furan-2-yl)-N-methyl-5-(phenylcarbamoylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C18H15N7O3
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1
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| 1 |
Ki = 1180 nM
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CP0417367
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8-Bromo-9-(sec-butyl)-9H-adenine
Show/Hide
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C9H12BrN5
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1
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| 1 |
Ki = 1200 nM
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CP0171808
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4-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid
Show/Hide
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C13H12N4O5S
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1
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| 1 |
Ki = 1330 nM
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CP0393015
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N-cyclobutyl-9-ethyl-8-phenylpurin-6-amine
Show/Hide
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C17H19N5
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1
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| 1 |
Ki = 1440 nM
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CP0850612
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8-Bromo-N2-phenethyl-9-propyl-9H-purine-2,6-diamine
Show/Hide
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C16H19BrN6
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1
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| 1 |
Ki = 1490 nM
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CP0414339
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ethyl 5-[(4-chlorophenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H16ClN5O3
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1
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| 1 |
Ki = 1630 nM
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CP0374987
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2-(3-(methylsulfonyl)-2-oxo-4-phenethyl-1,2-dihydroquinolin-6-yloxy)-N-phenylacetamide
Show/Hide
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C26H24N2O5S
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2
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| 1 |
Ki = 1675 nM
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| 2 |
Ki > 10000 nM
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CP0385412
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9-Propyl-9H-adenine
Show/Hide
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C8H11N5
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1
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| 1 |
Ki = 1700 nM
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CP0116394
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1-(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
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C22H22N8O3
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1
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| 1 |
Ki = 1715 nM
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CP0871535
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N2-Benzyl-8-bromo-9-propyl-9H-purine-2,6-diamine
Show/Hide
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C15H17BrN6
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1
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| 1 |
Ki = 1740 nM
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CP0414840
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N-cyclopropyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C14H13N7O
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1
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| 1 |
Ki = 1750 nM
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CP0851034
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8-Bromo-N-(3-phenylpropyl)-9-propyl-9H-purin-6-amine
Show/Hide
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C17H20BrN5
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1
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| 1 |
Ki = 1760 nM
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CP0868038
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N-benzyl-8-(furan-2-yl)-9-propyl-9H-purin-6-amine
Show/Hide
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C19H19N5O
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1
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| 1 |
Ki = 1760 nM
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CP0102757
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1-(3-Chloro-phenyl)-3-{2-furan-2-yl-8-[2-(2,4,5-tribromo-phenyl)-ethyl]-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl}-urea
Show/Hide
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C25H16Br3ClN8O2
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1
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| 1 |
Ki = 1861 nM
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CP0871533
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8-(Furan-2-yl)-N-(3-phenylpropyl)-9-propyl-9H-purin-6-amine
Show/Hide
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C21H23N5O
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1
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| 1 |
Ki = 1870 nM
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CP0456031
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ethyl 2-(furan-2-yl)-5-(phenylcarbamoylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H16N6O4
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1
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| 1 |
Ki = 1900 nM
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CP0380865
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ethyl 5-[(4-fluorophenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H16FN5O3
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1
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| 1 |
Ki = 1970 nM
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CP0116395
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1-(8-Allyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
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C21H18N8O3
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1
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| 1 |
Ki = 2030 nM
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CP0375195
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5-amino-2-(furan-2-yl)-N-methyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C11H10N6O2
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1
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| 1 |
Ki = 2030 nM
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CP0868036
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8-(Furan-2-yl)-N2-phenethyl-9-propyl-9H-purine-2,6-diamine
Show/Hide
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C20H22N6O
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1
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| 1 |
Ki = 2030 nM
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CP0396871
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ethyl 2-(furan-2-yl)-5-[[4-(trifluoromethyl)phenyl]methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C20H16F3N5O3
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1
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| 1 |
Ki = 2040 nM
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CP0053428
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1-[4-(furan-2-yl)-11-propyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C21H20N8O3
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2
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| 1 |
Ki = 2056 nM
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| 2 |
Ki = 2100 nM
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CP0430116
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4-(furan-2-yl)-N,11-dimethyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C12H11N7O
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1
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| 1 |
Ki = 2110 nM
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CP0388113
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N-ethyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C13H13N7O
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1
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| 1 |
Ki = 2160 nM
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CP0463482
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ethyl 5-(cyclopropylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C15H15N5O3
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1
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| 1 |
Ki = 2260 nM
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CP0396850
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ethyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C13H13N5O3
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1
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| 1 |
Ki = 2450 nM
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CP0419834
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5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-N-methyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C20H20N6O4
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1
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| 1 |
Ki = 2490 nM
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CP0406005
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N-[8-(furan-2-yl)-9-methylpurin-6-yl]-2-phenylacetamide
Show/Hide
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C18H15N5O2
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1
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| 1 |
Ki = 2510 nM
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CP0396829
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ethyl 5-(benzylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H17N5O3
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1
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| 1 |
Ki = 2510 nM
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CP0435342
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8-(3-chlorophenyl)-N-cyclopentyl-9-methylpurin-6-amine
Show/Hide
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C17H18ClN5
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1
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| 1 |
Ki = 2530 nM
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CP0391386
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N-[(2S)-butan-2-yl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C15H17N7O
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1
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| 1 |
Ki = 2600 nM
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CP0381296
|
N-[(4-chlorophenyl)methyl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C18H14ClN7O
|
1
|
| 1 |
Ki = 2620 nM
|
|
|
|
CP0397576
|
N-cyclopentyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C16H17N7O
|
1
|
| 1 |
Ki = 2650 nM
|
|
|
|
CP0386034
|
2-(4-isopentyl-2-oxo-3-(thiazol-2-yl)-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide
Show/Hide
|
C28H31N3O3S
|
1
|
| 1 |
Ki = 2669 nM
|
|
|
|
CP0399697
|
5'-chloro-5'-deoxy-N6-((-endo-norborn-2-yl)adenosine
Show/Hide
|
C17H22ClN5O3
|
1
|
| 1 |
Ki = 2740 nM
|
|
|
|
CP0387973
|
N-[8-(furan-2-yl)-9-methylpurin-6-yl]-2-[4-[(4-methylphenyl)methoxy]phenyl]acetamide
Show/Hide
|
C26H23N5O3
|
1
|
| 1 |
Ki = 2780 nM
|
|
|
|
CP0412572
|
4-(furan-2-yl)-11-methyl-N-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C19H17N7O
|
1
|
| 1 |
Ki = 2790 nM
|
|
|
|
CP0381882
|
2-(6-amino-8-bromo-9H-purin-9-yl)ethanol
Show/Hide
|
C7H8BrN5O
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0391188
|
2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-N-methylthiocarbamoyl-beta-D-ribofuranosyl)adenine
Show/Hide
|
C18H25ClN6O4S
|
1
|
| 1 |
Ki = 2810 nM
|
|
|
|
CP0396538
|
4-(furan-2-yl)-N-[2-(1H-indol-3-yl)ethyl]-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C21H18N8O
|
1
|
| 1 |
Ki = 2870 nM
|
|
|
|
CP0902330
|
[5-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)pentyl]carbamic acid tert-butyl ester
Show/Hide
|
C21H28N8O3
|
1
|
| 1 |
Ki = 3000 nM
|
|
|
|
CP0520036
|
9-ethyl-8-phenylpurin-6-amine
Show/Hide
|
C13H13N5
|
1
|
| 1 |
Ki = 3020 nM
|
|
|
|
CP0396836
|
ethyl 5-(ethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C14H15N5O3
|
1
|
| 1 |
Ki = 3060 nM
|
|
|
|
CP0388112
|
N-[(4-fluorophenyl)methyl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C18H14FN7O
|
1
|
| 1 |
Ki = 3180 nM
|
|
|
|
CP0911667
|
8-Bromo-N-phenethyl-9-propyl-9H-purin-6-amine
Show/Hide
|
C16H18BrN5
|
1
|
| 1 |
Ki = 3190 nM
|
|
|
|
CP0399699
|
(2S,3S,4R,5R)-2-(chloromethyl)-5-[6-(cyclopentylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C15H20ClN5O3
|
1
|
| 1 |
Ki = 3210 nM
|
|
|
|
CP0381298
|
N-benzyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C18H15N7O
|
1
|
| 1 |
Ki = 3330 nM
|
|
|
|
CP0386086
|
N-tert-butyl-2-[[2-oxo-4-(2-phenylethyl)-3-(1,3-thiazol-2-yl)-1H-quinolin-6-yl]oxy]acetamide
Show/Hide
|
C26H27N3O3S
|
2
|
| 1 |
Ki = 3413 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0519733
|
N-cyclopentyl-8-phenyl-9-propylpurin-6-amine
Show/Hide
|
C19H23N5
|
1
|
| 1 |
Ki = 3430 nM
|
|
|
|
CP0501647
|
6-methoxy-3-(methylsulfonyl)-4-phenethylquinolin-2(1H)-one
Show/Hide
|
C19H19NO4S
|
2
|
| 1 |
Ki = 3474 nM
|
|
|
| 2 |
Ki = 11310 nM
|
|
|
|
CP0501667
|
N-benzyl-2-[3-(2,4-difluorophenyl)-1-methyl-2-oxo-4-(2-phenylethyl)quinolin-6-yl]oxyacetamide
Show/Hide
|
C33H28F2N2O3
|
2
|
| 1 |
Ki = 3655 nM
|
|
|
| 2 |
Ki > 5000 nM
|
|
|
|
CP0394638
|
1-phenylethyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C19H17N5O3
|
1
|
| 1 |
Ki = 3720 nM
|
|
|
|
CP0393016
|
N-cyclobutyl-9-methyl-8-phenylpurin-6-amine
Show/Hide
|
C16H17N5
|
1
|
| 1 |
Ki = 3730 nM
|
|
|
|
CP0857913
|
(R,S)-(+,)-sec-Butyl-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e]-[1,2,4]triazolo[1,5-c]pyrimidin-5-yl)amine
Show/Hide
|
C15H17N7O
|
1
|
| 1 |
Ki = 3860 nM
|
|
|
|
CP0381326
|
N-[2-(3,4-dimethoxyphenyl)ethyl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C21H21N7O3
|
1
|
| 1 |
Ki = 3880 nM
|
|
|
|
CP0381297
|
4-(furan-2-yl)-11-methyl-N-[(4-methylphenyl)methyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C19H17N7O
|
1
|
| 1 |
Ki = 3940 nM
|
|
|
|
CP0381330
|
4-(furan-2-yl)-11-methyl-N-pentyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C16H19N7O
|
1
|
| 1 |
Ki = 3980 nM
|
|
|
|
CP0381888
|
8-Bromo-9-cyclobutyl-9H-adenine
Show/Hide
|
C9H10BrN5
|
1
|
| 1 |
Ki = 4100 nM
|
|
|
|
CP0381896
|
8-Bromo-9-isobutyl-9H-adenine
Show/Hide
|
C9H12BrN5
|
1
|
| 1 |
Ki = 4200 nM
|
|
|
|
CP0304418
|
2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
|
C22H17N7O
|
1
|
| 1 |
Ki = 4294 nM
|
|
|
|
CP0424788
|
2'-Me-tecadenoson
Show/Hide
|
C15H21N5O5
|
1
|
| 1 |
Ki = 4440 nM
|
|
|
|
CP0449107
|
2-chloro-2'-C-methyl-tecadenoson
Show/Hide
|
C15H20ClN5O5
|
1
|
| 1 |
Ki = 4470 nM
|
|
|
|
CP0374424
|
9-Allyl-8-bromo-9H-adenine
Show/Hide
|
C8H8BrN5
|
1
|
| 1 |
Ki = 4600 nM
|
|
|
|
CP0853605
|
N2-benzyl-8-(furan-2-yl)-9-propyl-9H-purine-2,6-diamine
Show/Hide
|
C19H20N6O
|
1
|
| 1 |
Ki = 4610 nM
|
|
|
|
CP0480188
|
ethyl 5-(cyclopentylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C17H19N5O3
|
1
|
| 1 |
Ki = 4620 nM
|
|
|
|
CP0396547
|
N-[(2R)-butan-2-yl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C15H17N7O
|
1
|
| 1 |
Ki = 4810 nM
|
|
|
|
CP0463483
|
ethyl 2-(furan-2-yl)-5-[(4-methoxyphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C20H19N5O4
|
1
|
| 1 |
Ki = 4810 nM
|
|
|
|
CP0503227
|
2,5'-dichloro-5'-deoxy-N6-cyclopentyladenosine
Show/Hide
|
C15H19Cl2N5O3
|
1
|
| 1 |
Ki = 4830 nM
|
|
|
|
CP0396853
|
2-(furan-2-yl)-N-methyl-5-[(2-phenylacetyl)amino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C19H16N6O3
|
1
|
| 1 |
Ki = 4840 nM
|
|
|
|
CP0082822
|
(2R,3R,4S,5R)-2-[6-(2-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C17H23N5O4
|
1
|
| 1 |
Ki = 4930 nM
|
|
|
|
CP0406004
|
N-[8-(furan-2-yl)-9-methylpurin-6-yl]-2-(4-phenylmethoxyphenyl)acetamide
Show/Hide
|
C25H21N5O3
|
1
|
| 1 |
Ki = 5070 nM
|
|
|
|
CP0394984
|
8-Bromo-9-(3-hydroxypropyl)-9H-adenine
Show/Hide
|
C8H10BrN5O
|
1
|
| 1 |
Ki = 5100 nM
|
|
|
|
CP0380533
|
2-(2-oxo-3-(thiazol-2-yl)-4-(3,3,3-trifluoropropyl)-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide
Show/Hide
|
C26H24F3N3O3S
|
1
|
| 1 |
Ki = 5155 nM
|
|
|
|
CP0386037
|
N-[(3,4-dichlorophenyl)methyl]-2-[(4-methyl-3-methylsulfonyl-2-oxo-1H-quinolin-6-yl)oxy]acetamide
Show/Hide
|
C20H18Cl2N2O5S
|
2
|
| 1 |
Ki = 5251 nM
|
|
|
| 2 |
Ki = 6670 nM
|
|
|
|
CP0414843
|
4-(furan-2-yl)-11-methyl-N-(4-phenylbutan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C21H21N7O
|
1
|
| 1 |
Ki = 5260 nM
|
|
|
|
CP0499430
|
4-(furan-2-yl)-11-methyl-N-[(1S)-1-phenylethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C19H17N7O
|
1
|
| 1 |
Ki = 5290 nM
|
|
|
|
CP0393013
|
N-cyclohexyl-8-phenyl-9-propylpurin-6-amine
Show/Hide
|
C20H25N5
|
1
|
| 1 |
Ki = 5310 nM
|
|
|
|
CP0411913
|
5-amino-2-(furan-2-yl)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C18H16N6O2
|
1
|
| 1 |
Ki = 5320 nM
|
|
|
|
CP0381889
|
8-Bromo-9-(2-butyl)-9H-adenine
Show/Hide
|
C9H12BrN5
|
1
|
| 1 |
Ki = 5600 nM
|
|
|
|
CP0435361
|
N-cyclopentyl-9-ethyl-8-phenylpurin-6-amine
Show/Hide
|
C18H21N5
|
1
|
| 1 |
Ki = 5790 nM
|
|
|
|
CP0393020
|
N-cyclopentyl-9-methyl-8-(3-methylphenyl)purin-6-amine
Show/Hide
|
C18H21N5
|
1
|
| 1 |
Ki = 6030 nM
|
|
|
|
CP0387255
|
ethyl 2-(furan-2-yl)-5-(2-phenylhydrazinyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C18H16N6O3
|
1
|
| 1 |
Ki = 6060 nM
|
|
|
|
CP0523028
|
1-[8-(furan-2-yl)-9-methylpurin-6-yl]-3-phenylurea
Show/Hide
|
C17H14N6O2
|
1
|
| 1 |
Ki = 6250 nM
|
|
|
|
CP0853604
|
8-Bromo-N2-(3-phenylpropyl)-9-propyl-9H-purine-2,6-diamine
Show/Hide
|
C17H21BrN6
|
1
|
| 1 |
Ki = 6300 nM
|
|
|
|
CP0391388
|
N-cyclohexyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C17H19N7O
|
1
|
| 1 |
Ki = 6320 nM
|
|
|
|
CP0491243
|
N-cycloheptyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C18H21N7O
|
1
|
| 1 |
Ki = 6590 nM
|
|
|
|
CP0490639
|
8-Bromo-9-(2,3-dihydroxypropyl)-9H-adenine
Show/Hide
|
C8H10BrN5O2
|
1
|
| 1 |
Ki = 7100 nM
|
|
|
|
CP0414535
|
ethyl 2-(furan-2-yl)-5-(2-methylpropylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C16H19N5O3
|
1
|
| 1 |
Ki = 7150 nM
|
|
|
|
CP0373160
|
9-(4-hydroxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
Show/Hide
|
C18H21N5O3
|
1
|
| 1 |
Ki = 7200 nM
|
|
|
|
CP0464673
|
2-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]ethanol
Show/Hide
|
C13H13N7O2
|
1
|
| 1 |
Ki = 7470 nM
|
|
|
|
CP0868035
|
N-benzyl-8-bromo-9-propyl-9H-purin-6-amine
Show/Hide
|
C15H16BrN5
|
1
|
| 1 |
Ki = 7490 nM
|
|
|
|
CP0397427
|
4-(furan-2-yl)-11-methyl-N-(2-phenoxyethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C19H17N7O2
|
1
|
| 1 |
Ki = 7500 nM
|
|
|
|
CP0468908
|
4-(furan-2-yl)-N-heptan-2-yl-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C18H23N7O
|
1
|
| 1 |
Ki = 7660 nM
|
|
|
|
CP0393017
|
9-methyl-8-phenylpurin-6-amine
Show/Hide
|
C12H11N5
|
1
|
| 1 |
Ki = 7790 nM
|
|
|
|
CP0536617
|
N-[5-[4-amino-6-(dimethylamino)-1,3,5-triazin-2-yl]-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
|
C19H17N7O2S
|
1
|
| 1 |
Ki = 8000 nM
|
|
|
|
CP0175614
|
8-(3-chlorostyryl)caffeine
Show/Hide
|
C16H15ClN4O2
|
2
|
| 1 |
Ki = 8200 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0860138
|
8-(Furan-2-yl)-N2-(3-phenylpropyl)-9-propyl-9H-purine-2,6-diamine
Show/Hide
|
C21H24N6O
|
1
|
| 1 |
Ki = 8240 nM
|
|
|
|
CP0394476
|
2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylcarbamoyl-beta-D-ribofuranosyl)adenine
Show/Hide
|
C18H25ClN6O5
|
1
|
| 1 |
Ki = 8350 nM
|
|
|
|
CP0396540
|
4-(furan-2-yl)-N-methoxy-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C12H11N7O2
|
1
|
| 1 |
Ki = 8500 nM
|
|
|
|
CP0520046
|
N-cyclopentyl-9-methyl-8-phenylpurin-6-amine
Show/Hide
|
C17H19N5
|
1
|
| 1 |
Ki = 8510 nM
|
|
|
|
CP0523458
|
N-cyclohexyl-9-ethyl-8-phenylpurin-6-amine
Show/Hide
|
C19H23N5
|
1
|
| 1 |
Ki = 9020 nM
|
|
|
|
CP0393014
|
N-(oxolan-3-yl)-8-phenyl-9-propylpurin-6-amine
Show/Hide
|
C18H21N5O
|
1
|
| 1 |
Ki = 9080 nM
|
|
|
|
CP0375421
|
N-[4-phenyl-5-(pyridine-2-carbonyl)-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
|
C20H13N3O3S
|
1
|
| 1 |
Ki = 9110 nM
|
|
|
|
CP0850599
|
N2-phenethyl-9-propyl-9H-purine-2,6-diamine
Show/Hide
|
C16H20N6
|
1
|
| 1 |
Ki = 9250 nM
|
|
|
|
CP0853599
|
8-(Furan-2-yl)-N-phenethyl-9-propyl-9H-purin-6-amine
Show/Hide
|
C20H21N5O
|
1
|
| 1 |
Ki = 9280 nM
|
|
|
|
CP0381325
|
3-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]propan-1-ol
Show/Hide
|
C14H15N7O2
|
1
|
| 1 |
Ki = 9300 nM
|
|
|
|
CP0391350
|
N-(cyclohexylmethyl)-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C18H21N7O
|
1
|
| 1 |
Ki = 9650 nM
|
|
|
|
CP0391353
|
4-(furan-2-yl)-11-methyl-N-propan-2-yl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C14H15N7O
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1
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| 1 |
Ki = 9720 nM
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CP0414838
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4-(furan-2-yl)-N-[(4-methoxyphenyl)methyl]-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H17N7O2
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1
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| 1 |
Ki = 9840 nM
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CP0139904
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1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea
Show/Hide
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C29H21ClN8O2
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1
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| 1 |
Ki > 10000 nM
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CP0220811
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1-{2-Furan-2-yl-8-[2-(2,4,5-tribromo-phenyl)-ethyl]-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl}-3-(4-methoxy-phenyl)-urea
Show/Hide
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C26H19Br3N8O3
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1
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| 1 |
Ki > 10000 nM
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CP0392989
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9-(2-(1H-indol-3-yl)ethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
Show/Hide
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C20H22N6O2
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1
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| 1 |
Ki = 10000 nM
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CP0405285
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9-(2-(4-chlorophenoxy)ethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
Show/Hide
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C18H20ClN5O3
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1
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| 1 |
Ki = 10000 nM
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CP0427936
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1,3-dimethyl-9-phenethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
Show/Hide
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C18H21N5O2
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1
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| 1 |
Ki = 10000 nM
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CP0489316
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9-(2-(benzylamino)ethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
Show/Hide
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C19H24N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0399694
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(2S,3S,4R,5R)-2-[(2-fluorophenyl)sulfanylmethyl]-5-[6-(oxolan-3-ylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C20H22FN5O4S
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1
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| 1 |
Ki > 10000 nM
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CP0399695
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2-Chloro-N6-(+/-)-endo-norbornyl-9H-(2-C-methyl-beta-D-ribofuranosyl)adenine
Show/Hide
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C18H24ClN5O4
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1
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| 1 |
Ki > 10000 nM
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CP0399698
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2-Chloro-N6-cyclopentyl-9H-[2-C-methyl-5-deoxy-5-(2-fluorophenylthio)-beta-D-ribofuranosyl]adenine
Show/Hide
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C22H25ClFN5O3S
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1
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| 1 |
Ki > 10000 nM
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CP0415591
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2-Chloro-N6-(+/-)-endo-norbornyl-9H-(5-chloro-5-deoxy-beta-D-ribofuranosyl)adenine
Show/Hide
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C17H21Cl2N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0415649
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2-Chloro-N6-(+/-)-endo-norbornyl-9H-[2-C-methyl-5-deoxy-5-(2-fluorophenylthio)-beta-D-ribofuranosyl]adenine
Show/Hide
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C24H27ClFN5O3S
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1
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| 1 |
Ki > 10000 nM
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CP0417325
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2-Chloro-N6-(+/-)-endo-norbornyl-9H-(2-C-methyl-5-chloro-5-deoxy-beta-D-ribofuranosyl)adenine
Show/Hide
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C18H23Cl2N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0433869
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(2R,3R,4R,5R)-2-[6-(2-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-(hydroxymethyl)-3-methyloxolane-3,4-diol
Show/Hide
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C18H25N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0433870
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(2R,3R,4S,5S)-2-[6-(cyclopentylamino)purin-9-yl]-5-[(2-fluorophenyl)sulfanylmethyl]oxolane-3,4-diol
Show/Hide
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C21H24FN5O3S
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1
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| 1 |
Ki > 10000 nM
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CP0474233
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2-Chloro-N6-cyclopentyl-9H-[5-deoxy-5-(2-fluorophenylthio)-beta-D-ribofuranosyl]adenine
Show/Hide
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C21H23ClFN5O3S
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1
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| 1 |
Ki > 10000 nM
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CP0485049
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(2R,3R,4R,5S)-2-[6-(2-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-(chloromethyl)-3-methyloxolane-3,4-diol
Show/Hide
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C18H24ClN5O3
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1
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| 1 |
Ki > 10000 nM
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CP0491862
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(2R,3R,4R,5S)-2-[6-(cyclopentylamino)purin-9-yl]-5-[(2-fluorophenyl)sulfanylmethyl]-3-methyloxolane-3,4-diol
Show/Hide
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C22H26FN5O3S
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1
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| 1 |
Ki > 10000 nM
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CP0491866
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(2R,3R,4R,5S)-2-[6-(2-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-[(2-fluorophenyl)sulfanylmethyl]-3-methyloxolane-3,4-diol
Show/Hide
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C24H28FN5O3S
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1
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| 1 |
Ki > 10000 nM
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CP0503246
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2-Chloro-N6-cyclopentyl-9H-(2-C-methyl-5-chloro-5-deoxy-beta-D-ribofuranosyl)adenine
Show/Hide
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C16H21Cl2N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0504201
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2-Chloro-N6-(+/-)-endo-norbornyl-9H-(beta-D-ribofuranosyl)adenine
Show/Hide
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C17H22ClN5O4
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1
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| 1 |
Ki > 10000 nM
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CP0510001
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(2R,3R,4R,5S)-5-(chloromethyl)-2-[6-(cyclopentylamino)purin-9-yl]-3-methyloxolane-3,4-diol
Show/Hide
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C16H22ClN5O3
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1
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| 1 |
Ki > 10000 nM
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CP0372973
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2-(4-Bromophenyl)-8-phenylethylpyrazolo[4,3-e]1,2,4-triazolo-[1,5-c]pyrimidin-5-amine
Show/Hide
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C20H16BrN7
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1
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| 1 |
Ki > 10000 nM
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CP0373122
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N-[4-(4-fluorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C21H16FN7O
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1
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| 1 |
Ki > 10000 nM
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CP0400007
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N-[4-phenyl-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C27H21N7O
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1
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| 1 |
Ki > 10000 nM
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CP0400008
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N-[4-(4-bromophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C21H16BrN7O
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1
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| 1 |
Ki > 10000 nM
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CP0400038
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2-(4-Bromophenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C13H10BrN7
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1
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| 1 |
Ki > 10000 nM
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CP0400041
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2-(Phenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C13H11N7
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1
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| 1 |
Ki > 10000 nM
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CP0400043
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N-[11-methyl-4-(4-nitrophenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C20H14N8O3
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1
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| 1 |
Ki > 10000 nM
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CP0400044
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N-benzoyl-N-[4-(4-methoxyphenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C28H21N7O3
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1
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| 1 |
Ki > 10000 nM
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CP0414910
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2-(4-Fluorophenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C13H10FN7
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1
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| 1 |
Ki > 10000 nM
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CP0417738
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2-(4-Methoxyphenyl)-8-phenylethylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C21H19N7O
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1
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| 1 |
Ki > 10000 nM
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CP0436832
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2-(4-Nitrophenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C13H10N8O2
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1
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| 1 |
Ki > 10000 nM
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CP0453430
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2-(4-Chloro-phenyl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C20H16ClN7
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1
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| 1 |
Ki > 10000 nM
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CP0477668
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N-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C21H16ClN7O
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1
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| 1 |
Ki > 10000 nM
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CP0477669
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2-(4-Fluorophenyl)-8-phenylethylpyrazolo[4,3-e]1,2,4-triazolo-[1,5-c]pyrimidin-5-amine
Show/Hide
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C20H16FN7
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1
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| 1 |
Ki > 10000 nM
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CP0490809
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2-(4-Chlorophenyl)-7-ethylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C14H12ClN7
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1
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| 1 |
Ki > 10000 nM
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CP0493941
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N-[4-(4-bromophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C20H14BrN7O
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1
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| 1 |
Ki > 10000 nM
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CP0493943
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N-(11-methyl-4-phenyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl)-2-phenylacetamide
Show/Hide
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C21H17N7O
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1
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| 1 |
Ki > 10000 nM
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CP0493947
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N-benzoyl-N-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C27H18ClN7O2
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1
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| 1 |
Ki > 10000 nM
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CP0493949
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2-(4-Chlorophenyl)-8-phenylethylpyrazolo[4,3-e]1,2,4-triazolo-[1,5-c]pyrimidin-5-amine
Show/Hide
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C20H16ClN7
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1
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| 1 |
Ki > 10000 nM
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CP0493965
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N-(11-methyl-4-phenyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl)benzamide
Show/Hide
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C20H15N7O
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1
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| 1 |
Ki > 10000 nM
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CP0495890
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N-[11-methyl-4-(4-nitrophenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C21H16N8O3
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1
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| 1 |
Ki > 10000 nM
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CP0502326
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N-[4-(4-bromophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C27H20BrN7O
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1
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| 1 |
Ki > 10000 nM
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CP0504230
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N-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C20H14ClN7O
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1
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| 1 |
Ki > 10000 nM
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CP0504260
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2-(Phenyl)-8-phenylethylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C20H17N7
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1
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| 1 |
Ki > 10000 nM
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CP0504275
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N-[4-(4-methoxyphenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C22H19N7O2
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1
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| 1 |
Ki > 10000 nM
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CP0506236
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2-(4-Chlorophenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C13H10ClN7
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1
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| 1 |
Ki > 10000 nM
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CP0507716
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N-[4-(4-methoxyphenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C21H17N7O2
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1
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| 1 |
Ki > 10000 nM
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CP0508354
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2-(4-Methoxyphenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo-[1,5-c]pyrimidin-5-amine
Show/Hide
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C14H13N7O
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1
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| 1 |
Ki > 10000 nM
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CP0514610
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N-[4-(4-fluorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C20H14FN7O
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1
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| 1 |
Ki > 10000 nM
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CP0514611
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2-(4-Chlorophenyl)-8-ethylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C14H12ClN7
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1
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| 1 |
Ki > 10000 nM
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CP0501668
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N-(cyclopropylmethyl)-2-[[3-methylsulfonyl-2-oxo-4-(2-phenylethyl)-1H-quinolin-6-yl]oxy]acetamide
Show/Hide
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C24H26N2O5S
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2
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| 1 |
Ki > 10000 nM
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| 2 |
Ki > 5000 nM
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CP0501818
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2-(3-(2,4-difluorophenyl)-2-oxo-4-phenethyl-1,2-dihydroquinolin-6-yloxy)-N-(3-methoxypropyl)acetamide
Show/Hide
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C29H28F2N2O4
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2
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| 1 |
Ki > 10000 nM
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| 2 |
Ki > 5000 nM
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CP0386038
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N-[(3,4-dichlorophenyl)methyl]-2-[(3-methylsulfonyl-2-oxo-4-phenyl-1H-quinolin-6-yl)oxy]acetamide
Show/Hide
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C25H20Cl2N2O5S
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1
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| 1 |
Ki > 10000 nM
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CP0390093
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1-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C21H17ClN8O2
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1
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| 1 |
Ki > 10000 nM
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CP0390094
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1-[4-(4-bromophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-phenylurea
Show/Hide
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C20H15BrN8O
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1
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| 1 |
Ki > 10000 nM
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CP0390097
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11-methyl-4-(4-phenylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H15N7
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1
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| 1 |
Ki > 10000 nM
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CP0390259
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1-[11-methyl-4-[4-(trifluoromethyl)phenyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-phenylurea
Show/Hide
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C21H15F3N8O
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1
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| 1 |
Ki > 10000 nM
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CP0390264
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1-(4-methoxyphenyl)-3-[11-methyl-4-[4-(trifluoromethyl)phenyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C22H17F3N8O2
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1
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| 1 |
Ki > 10000 nM
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CP0440624
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1-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-phenylurea
Show/Hide
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C20H15ClN8O
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1
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| 1 |
Ki > 10000 nM
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CP0440625
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1-(4-fluorophenyl)-3-[11-methyl-4-[4-(trifluoromethyl)phenyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C21H14F4N8O
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1
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| 1 |
Ki > 10000 nM
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CP0440626
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1-(4-fluorophenyl)-3-[11-methyl-4-(4-phenylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C26H19FN8O
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1
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| 1 |
Ki > 10000 nM
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|
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CP0452422
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1-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-fluorophenyl)urea
Show/Hide
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C20H14ClFN8O
|
1
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| 1 |
Ki > 10000 nM
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CP0452426
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N-[4-(4-methoxyphenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C28H23N7O2
|
1
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| 1 |
Ki > 10000 nM
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|
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CP0460006
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N-[4-(4-bromophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C28H22BrN7O
|
1
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| 1 |
Ki > 10000 nM
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|
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CP0460007
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11-methyl-4-[4-(trifluoromethyl)phenyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C14H10F3N7
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1
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| 1 |
Ki > 10000 nM
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CP0468299
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1-[4-(4-bromophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C21H17BrN8O2
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1
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| 1 |
Ki > 10000 nM
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CP0471024
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1-[4-(4-bromophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-fluorophenyl)urea
Show/Hide
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C20H14BrFN8O
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1
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| 1 |
Ki > 10000 nM
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CP0486047
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1-(4-methoxyphenyl)-3-[11-methyl-4-(4-phenylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C27H22N8O2
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1
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| 1 |
Ki > 10000 nM
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CP0486048
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1-[11-methyl-4-(4-phenylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-phenylurea
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C26H20N8O
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1
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| 1 |
Ki > 10000 nM
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CP0160749
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4-[2-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]sulfanylethyl]benzoic acid
Show/Hide
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C19H21N5O6S
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1
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| 1 |
Ki > 10000 nM
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CP0280427
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4-[2-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]sulfanylethyl]benzenesulfonic acid
Show/Hide
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C18H21N5O7S2
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1
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| 1 |
Ki > 10000 nM
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CP0376574
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CHEMBL2153622
Show/Hide
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C18H25N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0381030
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9-[2-(cyclohexen-1-yl)ethyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C18H25N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0381031
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9-cyclohexyl-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C16H23N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0381032
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9-cyclobutyl-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C14H19N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0404908
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9-cycloheptyl-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C17H25N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0433620
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9-(1-adamantyl)-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C20H27N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0456892
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10-cyclooctyl-1,3-dimethyl-6,7,8,9-tetrahydropurino[7,8-a][1,3]diazepine-2,4-dione
Show/Hide
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C19H29N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0489090
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6-cyclohexyl-2,4-dimethyl-7,8-dihydropurino[7,8-a]imidazole-1,3-dione
Show/Hide
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C15H21N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0848773
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trans-9-(4-hydroxycyclohexyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-f]purine-2,4(1H,3H)-dione
Show/Hide
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C16H23N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0300598
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1,3-dimethyl-9-(4-methylcyclohexyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C17H25N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0376573
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9-cyclooctyl-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C18H27N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0446021
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6-(4-hydroxycyclohexyl)-2,4-dimethyl-7,8-dihydropurino[7,8-a]imidazole-1,3-dione
Show/Hide
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C15H21N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0489088
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[4-(1,3-dimethyl-2,4-dioxo-6,7,8,9-tetrahydropurino[7,8-a][1,3]diazepin-10-yl)cyclohexyl] acetate
Show/Hide
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C19H27N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0130086
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8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione
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C20H24N4O4
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2
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| 1 |
Ki >= 10000 nM
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| 2 |
Ki > 10000 nM
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CP0376844
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6-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]hexan-1-ol
Show/Hide
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C17H21N7O2
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1
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| 1 |
Ki > 10000 nM
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CP0379873
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7-chloro-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
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C11H7ClN6O
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1
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| 1 |
Ki > 10000 nM
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CP0380000
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4-(furan-2-yl)-11-methyl-N-[(4-phenylphenyl)methyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C24H19N7O
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1
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| 1 |
Ki > 10000 nM
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CP0381299
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2-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]butan-1-ol
Show/Hide
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C15H17N7O2
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1
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| 1 |
Ki > 10000 nM
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CP0388103
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4-(furan-2-yl)-7-methoxy-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
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C12H10N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0388104
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2-[ethyl-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]ethanol
Show/Hide
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C15H17N7O2
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1
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| 1 |
Ki > 10000 nM
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CP0388105
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4-(furan-2-yl)-N,N,11-trimethyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C13H13N7O
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1
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| 1 |
Ki > 10000 nM
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CP0388106
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]butan-1-ol
Show/Hide
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C15H17N7O2
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1
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| 1 |
Ki > 10000 nM
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CP0388139
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N-benzhydryl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C24H19N7O
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1
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| 1 |
Ki > 10000 nM
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CP0391349
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N-(2-adamantyl)-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C21H23N7O
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1
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| 1 |
Ki > 10000 nM
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CP0391351
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4-(furan-2-yl)-11-methyl-N-octan-2-yl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H25N7O
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1
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| 1 |
Ki > 10000 nM
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CP0391355
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4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,9-tetraen-7-one
Show/Hide
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C11H8N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0391387
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N-butyl-4-(furan-2-yl)-N,11-dimethyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C16H19N7O
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1
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| 1 |
Ki > 10000 nM
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CP0396548
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2-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]propane-1,3-diol
Show/Hide
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C14H15N7O3
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1
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| 1 |
Ki > 10000 nM
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CP0397419
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4-(furan-2-yl)-11-methyl-7-(4-methylpiperazin-1-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
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C16H18N8O
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1
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| 1 |
Ki > 10000 nM
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CP0397420
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4-(furan-2-yl)-11-methyl-7-piperidin-1-yl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
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C16H17N7O
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1
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| 1 |
Ki > 10000 nM
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CP0397423
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4-(furan-2-yl)-N-(2-methoxyethyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C14H15N7O2
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1
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| 1 |
Ki > 10000 nM
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CP0397425
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N-(1-adamantyl)-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C21H23N7O
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1
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| 1 |
Ki > 10000 nM
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CP0397612
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7-ethoxy-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
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C13H12N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0397615
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5-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]pentan-1-ol
Show/Hide
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C16H19N7O2
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1
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| 1 |
Ki > 10000 nM
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CP0399190
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N-(2-ethylhexyl)-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H25N7O
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1
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| 1 |
Ki > 10000 nM
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CP0412573
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4-(furan-2-yl)-11-methyl-N-(2,3,3-trimethylbutan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C18H23N7O
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1
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| 1 |
Ki > 10000 nM
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CP0412629
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4-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]morpholine
Show/Hide
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C15H15N7O2
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1
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| 1 |
Ki > 10000 nM
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CP0414841
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N,N-diethyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C15H17N7O
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1
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| 1 |
Ki > 10000 nM
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CP0441104
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N-cyclohexyl-4-(furan-2-yl)-N,11-dimethyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C18H21N7O
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1
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| 1 |
Ki > 10000 nM
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CP0441105
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N-benzyl-4-(furan-2-yl)-N,11-dimethyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H17N7O
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1
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| 1 |
Ki > 10000 nM
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CP0464677
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4-(furan-2-yl)-11-methyl-7-pyrrolidin-1-yl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
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C15H15N7O
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1
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| 1 |
Ki > 10000 nM
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CP0467109
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N,N-dibenzyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C25H21N7O
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1
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| 1 |
Ki > 10000 nM
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CP0467110
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4-(furan-2-yl)-11-methyl-N,N-dipentyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C21H29N7O
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1
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| 1 |
Ki > 10000 nM
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CP0488587
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N-cyclooctyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H23N7O
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1
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| 1 |
Ki > 10000 nM
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CP0054094
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Binodenoson
Show/Hide
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C17H25N7O4
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1
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| 1 |
Ki > 10000 nM
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CP0851151
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(2S,3R,4S,E)-5-(2-(6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-2-methylhydrazono)hexane-1,2,3,4,6-pentaol
Show/Hide
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C17H27N7O9
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1
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| 1 |
Ki > 10000 nM
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CP0851152
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(2S,3S,4S,5S,E)-6-(2-(6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-2-methylhydrazono)hexane-1,2,3,4,5-pentaol
Show/Hide
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C17H27N7O9
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1
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| 1 |
Ki > 10000 nM
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CP0853684
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(2S,3S,4S,5R,E)-6-(2-(6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-2-methylhydrazono)hexane-1,2,3,4,5-pentaol
Show/Hide
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C17H27N7O9
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1
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| 1 |
Ki > 10000 nM
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CP0853685
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(2S,3R,4R,E)-5-(2-(6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)hydrazono)pentane-1,2,3,4-tetraol
Show/Hide
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C15H23N7O8
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1
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| 1 |
Ki > 10000 nM
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|
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CP0868084
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(2S,3R,4S,5R,E)-6-(2-(6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)hydrazono)hexane-1,2,3,4,5-pentaol
Show/Hide
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C16H25N7O9
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1
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| 1 |
Ki > 10000 nM
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CP0873066
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(2S,3R,4S,E)-5-(2-(6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)hydrazono)hexane-1,2,3,4,6-pentaol
Show/Hide
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C16H25N7O9
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1
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| 1 |
Ki > 10000 nM
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CP0876607
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(2S,3S,4S,5R,E)-6-(2-(6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)hydrazono)hexane-1,2,3,4,5-pentaol
Show/Hide
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C16H25N7O9
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1
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| 1 |
Ki > 10000 nM
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CP0886337
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(2S,3R,4R,E)-5-(2-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-2-methylhydrazono)pentane-1,2,3,4-tetraol
Show/Hide
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C16H25N7O8
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1
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| 1 |
Ki > 10000 nM
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|
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CP0886338
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(2R,3S,4R,5S,E)-6-(2-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-2-methylhydrazono)hexane-1,2,3,4,5-pentaol
Show/Hide
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C17H27N7O9
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1
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| 1 |
Ki > 10000 nM
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|
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CP0911499
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(2S,3S,4S,5S,E)-6-(2-(6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)hydrazono)hexane-1,2,3,4,5-pentaol
Show/Hide
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C16H25N7O9
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1
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| 1 |
Ki > 10000 nM
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CP0380971
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N-[5-(4-amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]-4-methoxybenzamide
Show/Hide
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C25H21N5O2S2
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1
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| 1 |
Ki > 10000 nM
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CP0380974
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N-[4-phenyl-5-(pyridine-3-carbonyl)-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C20H13N3O3S
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1
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| 1 |
Ki > 10000 nM
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CP0396622
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N-[5-(4-amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C22H17N5O2S2
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1
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| 1 |
Ki > 10000 nM
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CP0396639
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N-[5-(4-amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C24H19N5O2S2
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1
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| 1 |
Ki > 10000 nM
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CP0397156
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N-[5-(4-amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]-4-methoxybenzamide
Show/Hide
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C27H23N5O2S2
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1
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| 1 |
Ki > 10000 nM
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CP0397157
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4-methoxy-N-[4-phenyl-5-(pyridine-3-carbonyl)-1,3-thiazol-2-yl]benzamide
Show/Hide
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C23H17N3O3S
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1
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| 1 |
Ki > 10000 nM
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CP0397158
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N-[5-[4-amino-6-(dimethylamino)-1,3,5-triazine-2-carbonyl]-4-phenyl-1,3-thiazol-2-yl]-4-methoxybenzamide
Show/Hide
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C23H21N7O3S
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1
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| 1 |
Ki > 10000 nM
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CP0397160
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N-[5-[4-amino-6-(dimethylamino)-1,3,5-triazin-2-yl]-4-phenyl-1,3-thiazol-2-yl]benzamide
Show/Hide
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C21H19N7OS
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1
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| 1 |
Ki > 10000 nM
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CP0397161
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4-methoxy-N-[4-phenyl-5-(pyridine-2-carbonyl)-1,3-thiazol-2-yl]benzamide
Show/Hide
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C23H17N3O3S
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1
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| 1 |
Ki > 10000 nM
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CP0440163
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N-[5-(4-amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]benzamide
Show/Hide
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C26H21N5OS2
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1
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| 1 |
Ki > 10000 nM
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CP0465316
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N-[5-(4-amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]-4-methylbenzamide
Show/Hide
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C27H23N5OS2
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1
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| 1 |
Ki > 10000 nM
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CP0465317
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N-[5-(5,6-dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C22H16N4O3S2
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1
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| 1 |
Ki > 10000 nM
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CP0465318
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N-[5-(4-amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]benzamide
Show/Hide
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C24H19N5OS2
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1
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| 1 |
Ki > 10000 nM
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CP0489123
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N-[5-(4-amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]-4-methylbenzamide
Show/Hide
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C25H21N5OS2
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1
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| 1 |
Ki > 10000 nM
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CP0489124
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N-[5-(4-oxo-3H-quinazolin-2-yl)-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C22H14N4O3S
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1
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| 1 |
Ki > 10000 nM
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CP0395576
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4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-amine
Show/Hide
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C8H10ClN5
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1
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| 1 |
Ki > 10000 nM
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CP0395583
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4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-amine
Show/Hide
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C10H14ClN5
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1
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| 1 |
Ki > 10000 nM
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CP0435752
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N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-methylbenzamide
Show/Hide
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C18H20ClN5O
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1
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| 1 |
Ki > 10000 nM
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CP0435753
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N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)-2-phenylacetamide
Show/Hide
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C16H16ClN5O
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1
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| 1 |
Ki > 10000 nM
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CP0435770
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N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-fluorobenzamide
Show/Hide
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C17H17ClFN5O
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1
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| 1 |
Ki > 10000 nM
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CP0469079
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N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]benzamide
Show/Hide
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C17H18ClN5O
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1
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| 1 |
Ki >= 10000 nM
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CP0069173
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2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C20H19N7O2
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1
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| 1 |
Ki > 10000 nM
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CP0379815
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2-(furan-2-yl)-5-(pentylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C15H17N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0379837
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ethyl 5-(dimethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C14H15N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0379840
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5-(2-ethylhexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C18H23N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0380868
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ethyl 2-(furan-2-yl)-5-(2-methoxyethylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C15H17N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0380871
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ethyl 5-(cyclohexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H21N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0380873
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5-(cyclopropylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C13H11N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0396839
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ethyl 2-(furan-2-yl)-5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C16H17N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0396846
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5-(cyclohexylmethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C17H19N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0396864
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5-(benzylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C17H13N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0396869
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ethyl 2-(furan-2-yl)-5-(pentylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C17H21N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0414365
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2-(furan-2-yl)-5-(propan-2-ylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C13H13N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0414534
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ethyl 2-(furan-2-yl)-5-(morpholin-4-ylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C16H18N6O4
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1
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| 1 |
Ki > 10000 nM
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CP0419805
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2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C11H9N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0419826
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5-(ethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C12H11N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0419830
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5-(cyclopentylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C15H15N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0419833
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2-(furan-2-yl)-5-[(4-methylphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C18H15N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0456019
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ethyl 2-(furan-2-yl)-5-(methoxyamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C13H13N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0463447
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4-(cyclooctylmethyl)-2-cyclopenta-1,3-dien-1-yl-7-pent-1-en-2-yl-3aH-indene
Show/Hide
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C28H36
|
1
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| 1 |
Ki > 10000 nM
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CP0463449
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ethyl 2-(furan-2-yl)-5-piperidin-1-yl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C17H19N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0463478
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ethyl 2-(furan-2-yl)-5-(propan-2-ylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C15H17N5O3
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1
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| 1 |
Ki = 10000 nM
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CP0463480
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ethyl 5-(2-ethylhexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C20H27N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0480581
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ethyl 5-(cyclohexylmethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H23N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0487927
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ethyl 5-(cycloheptylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H23N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0490590
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ethyl 2-(furan-2-yl)-5-[(4-methylphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C20H19N5O3
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1
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| 1 |
Ki = 10000 nM
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CP0542031
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ethyl 2-(furan-2-yl)-5-pyrrolidin-1-yl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C16H17N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0413573
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ethyl 6-[(2-phenylacetyl)amino]-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C24H23N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0418074
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ethyl 6-benzamido-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C23H21N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0418718
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ethyl 6-[(2-phenylacetyl)amino]-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C19H21N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0453426
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ethyl 6-benzamido-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C18H19N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0469804
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ethyl 6-amino-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C11H15N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0852522
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(2-amino-1-(4-fluorophenyl)-1H-imidazol-5-yl)(4-methyl-2-(p-tolylamino)thiazol-5-yl)methanone
Show/Hide
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C21H18FN5OS
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1
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| 1 |
Ki > 10000 nM
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CP0857113
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(2-amino-1-(4-methoxyphenyl)-1H-imidazol-5-yl)(4-methyl-2-(phenylamino)thiazol-5-yl)methanone
Show/Hide
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C21H19N5O2S
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1
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| 1 |
Ki > 10000 nM
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CP0862330
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(2-amino-1-(4-fluorophenyl)-1H-imidazol-5-yl)(2-(4-chlorophenylamino)-4-methylthiazol-5-yl)methanone
Show/Hide
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C20H15ClFN5OS
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1
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| 1 |
Ki > 10000 nM
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CP0862331
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N-(5-(2-amino-1-(4-chlorophenyl)-1H-imidazole-5-carbonyl)-4-(dimethylamino)thiazol-2-yl)benzamide
Show/Hide
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C22H19ClN6O2S
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1
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| 1 |
Ki > 10000 nM
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CP0864681
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N-(5-(2-amino-1-(4-(trifluoromethyl)phenyl)-1H-imidazole-5-carbonyl)-4-(dimethylamino)thiazol-2-yl)benzamide
Show/Hide
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C23H19F3N6O2S
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1
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| 1 |
Ki > 10000 nM
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CP0864683
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(2-amino-1-(4-methoxyphenyl)-1H-imidazol-5-yl)(2-(4-chlorophenylamino)-4-methylthiazol-5-yl)methanone
Show/Hide
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C21H18ClN5O2S
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1
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| 1 |
Ki > 10000 nM
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CP0864685
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(2-amino-1-(4-methoxyphenyl)-1H-imidazol-5-yl)(2-morpholino-4-phenylthiazol-5-yl)methanone
Show/Hide
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C24H23N5O3S
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1
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| 1 |
Ki > 10000 nM
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CP0864687
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(2-amino-1-p-tolyl-1H-imidazol-5-yl)(2-morpholino-4-phenylthiazol-5-yl)methanone
Show/Hide
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C24H23N5O2S
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1
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| 1 |
Ki > 10000 nM
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CP0869630
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(2-amino-1-(4-chlorophenyl)-1H-imidazol-5-yl)(4-methyl-2-(phenylamino)thiazol-5-yl)methanone
Show/Hide
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C20H16ClN5OS
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1
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| 1 |
Ki > 10000 nM
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CP0871830
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(2-amino-1-(4-methoxyphenyl)-1H-imidazol-5-yl)(4-phenyl-2-(phenylamino)thiazol-5-yl)methanone
Show/Hide
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C26H21N5O2S
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1
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| 1 |
Ki > 10000 nM
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CP0900160
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(2-amino-1-(4-fluorophenyl)-1H-imidazol-5-yl)(4-phenyl-2-(phenylamino)thiazol-5-yl)methanone
Show/Hide
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C25H18FN5OS
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1
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| 1 |
Ki > 10000 nM
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CP0911940
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(2-amino-1-(4-fluorophenyl)-1H-imidazol-5-yl)(4-methyl-2-(phenylamino)thiazol-5-yl)methanone
Show/Hide
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C20H16FN5OS
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1
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| 1 |
Ki > 10000 nM
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CP0017043
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(2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxy-N-methyloxolane-2-carboxamide
Show/Hide
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C18H18ClIN6O4
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1
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| 1 |
Ki > 10000 nM
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CP0386797
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ethyl 2-(furan-2-yl)-5-piperazin-1-yl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C16H18N6O3
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1
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| 1 |
Ki > 10000 nM
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CP0386799
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(4-methylphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H17N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0386800
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ethyl 5-ethoxy-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C14H14N4O4
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1
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| 1 |
Ki > 10000 nM
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CP0387249
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2-(furan-2-yl)-5-(methylamino)-N'-phenyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carbohydrazide
Show/Hide
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C17H15N7O2
|
1
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| 1 |
Ki > 10000 nM
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CP0387250
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N-[(3,4-dimethoxyphenyl)methyl]-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C20H20N6O4
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1
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| 1 |
Ki > 10000 nM
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CP0387251
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N-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C18H15FN6O2
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1
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| 1 |
Ki > 10000 nM
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CP0387252
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(3-chlorophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C18H14ClN5O3
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1
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| 1 |
Ki = 10000 nM
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CP0387253
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ethyl 2-(furan-2-yl)-5-[2-[(2-methylpropan-2-yl)oxycarbonyl]hydrazinyl]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C17H20N6O5
|
1
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| 1 |
Ki > 10000 nM
|
|
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CP0391509
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N-[(4-chlorophenyl)methyl]-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C18H15ClN6O2
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1
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| 1 |
Ki > 10000 nM
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|
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CP0391512
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2-(furan-2-yl)-5-(methylamino)-N-[[4-(trifluoromethyl)phenyl]methyl]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C19H15F3N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0391513
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2-(furan-2-yl)-5-(methylamino)-N-[(4-methylphenyl)methyl]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C19H18N6O2
|
1
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| 1 |
Ki > 10000 nM
|
|
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CP0391514
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(4-fluorophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C18H14FN5O3
|
1
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| 1 |
Ki > 10000 nM
|
|
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CP0391515
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(4-chlorophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C18H14ClN5O3
|
1
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| 1 |
Ki > 10000 nM
|
|
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CP0391516
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(2-methoxyphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C19H17N5O4
|
1
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| 1 |
Ki > 10000 nM
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|
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CP0391517
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2-(furan-2-yl)-5-(methylamino)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C19H18N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0391518
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N-benzyl-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C18H16N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0391521
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ethyl 2-[[8-[(2-ethoxy-2-oxoethyl)carbamoyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidin-5-yl]amino]acetate
Show/Hide
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C18H20N6O6
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1
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| 1 |
Ki > 10000 nM
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CP0391522
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ethyl 2-(furan-2-yl)-5-hydrazinyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C12H12N6O3
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1
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| 1 |
Ki > 10000 nM
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CP0394624
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2-(furan-2-yl)-5-(methylamino)-N-[(4-phenylphenyl)methyl]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C24H20N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0394625
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2-(furan-2-yl)-N-[(4-methoxyphenyl)methyl]-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C19H18N6O3
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1
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| 1 |
Ki > 10000 nM
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CP0394626
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(3-fluorophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C18H14FN5O3
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1
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| 1 |
Ki > 10000 nM
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CP0394627
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(2-chlorophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H14ClN5O3
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1
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| 1 |
Ki > 10000 nM
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CP0394634
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2-(furan-2-yl)-5-(methylamino)-N-(2-phenoxyethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C19H18N6O3
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1
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| 1 |
Ki > 10000 nM
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CP0394639
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(2-methylphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C19H17N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0394641
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benzhydryl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C24H19N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0394646
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ethyl 2-(furan-2-yl)-5-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C21H26N6O5
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1
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| 1 |
Ki > 10000 nM
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CP0416700
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(3-methylphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C19H17N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0434927
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(2-bromophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H14BrN5O3
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1
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| 1 |
Ki > 10000 nM
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CP0434928
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(4-ethylphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C20H19N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0477180
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(4-methoxyphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H17N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0477181
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N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C21H22N6O4
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1
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| 1 |
Ki > 10000 nM
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CP0534944
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N-benzhydryl-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C24H20N6O2
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1
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| 1 |
Ki = 10000 nM
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CP0870386
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3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-ylamino)propyl-ammonium chloride
Show/Hide
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C14H17ClN8O
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1
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| 1 |
Ki > 10000 nM
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CP0870387
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3-(2-{2-[3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidin-5-ylamino)propoxy]ethoxy}ethoxy)propyl-ammonium chloride
Show/Hide
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C21H31ClN8O4
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1
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| 1 |
Ki > 10000 nM
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CP0870388
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4-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-piperazin-1-ium chloride
Show/Hide
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C15H17ClN8O
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1
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| 1 |
Ki > 10000 nM
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CP0882742
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[2-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)ethyl]carbamic acid tert-butyl ester
Show/Hide
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C18H22N8O3
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1
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| 1 |
Ki > 10000 nM
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CP0882746
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{4-[(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)methyl]cyclohexylmethyl}carbamic acid tert-butyl ester
Show/Hide
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C24H32N8O3
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1
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| 1 |
Ki = 10000 nM
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CP0882747
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2-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-ylamino)ethyl-ammonium chloride
Show/Hide
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C13H15ClN8O
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1
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| 1 |
Ki > 10000 nM
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CP0902320
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4-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)piperazine-1-carboxylic acid tert-butyl ester
Show/Hide
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C20H24N8O3
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1
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| 1 |
Ki > 10000 nM
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CP0902328
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N'-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)hydrazine carboxylic acid tert-butyl ester
Show/Hide
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C16H18N8O3
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1
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| 1 |
Ki > 10000 nM
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CP0902329
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2-{2-[2-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidin-5-ylamino)ethoxy]ethoxy}ethyl-ammonium chloride
Show/Hide
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C17H23ClN8O3
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1
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| 1 |
Ki > 10000 nM
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CP0929329
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(2-{2-[2-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidin-5-ylamino)ethoxy]ethoxy}ethyl)carbamic acid tert-butyl ester
Show/Hide
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C22H30N8O5
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1
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| 1 |
Ki > 10000 nM
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CP0929330
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N-((4-(Aminomethyl)cyclohexyl)methyl)-2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5yl-ammonium chloride
Show/Hide
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C19H25ClN8O
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1
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| 1 |
Ki > 10000 nM
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CP0943821
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[3-(2-{2-[3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)propoxy]ethoxy}ethoxy)propyl]carbamic acid tert-butyl ester
Show/Hide
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C26H38N8O6
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1
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| 1 |
Ki > 10000 nM
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CP0944003
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N'-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)hydrazinium chloride
Show/Hide
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C11H11ClN8O
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1
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| 1 |
Ki > 10000 nM
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CP0018686
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(2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide
Show/Hide
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C18H19IN6O4
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1
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| 1 |
Ki = 11000 nM
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CP0412439
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9-ethyl-N-(oxolan-3-yl)-8-phenylpurin-6-amine
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C17H19N5O
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1
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| 1 |
Ki = 11500 nM
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CP0947568
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[4-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)butyl]carbamic acid tert-butyl ester
Show/Hide
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C20H26N8O3
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1
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| 1 |
Ki = 11500 nM
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CP0417215
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2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl-5-N-methylthiocarbamoyl-beta-D-ribofuranosyl)adenine
Show/Hide
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C17H23ClN6O5S
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1
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| 1 |
Ki = 12100 nM
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CP0414839
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4-(furan-2-yl)-11-methyl-N-[(1R)-1-phenylethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H17N7O
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1
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| 1 |
Ki = 12200 nM
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CP0445312
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9-(cyclopropylmethyl)-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C14H19N5O2
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1
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| 1 |
Ki = 12500 nM
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CP0396848
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ethyl 5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C21H21N5O5
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1
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| 1 |
Ki = 13300 nM
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CP0393018
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9-methyl-N-(oxolan-3-yl)-8-phenylpurin-6-amine
Show/Hide
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C16H17N5O
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1
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| 1 |
Ki = 13300 nM
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CP0505594
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1,3-dimethyl-9-(2-(pyridin-2-yl)ethyl)-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
Show/Hide
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C17H20N6O2
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1
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| 1 |
Ki = 13400 nM
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CP0445453
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ethyl 6-amino-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C13H19N5O2
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1
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| 1 |
Ki > 15000 nM
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CP0381881
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9-Isopropyl-9H-adenine
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C8H11N5
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1
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| 1 |
Ki = 16000 nM
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CP0467851
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9-Cyclobutyl-9H-adenine
Show/Hide
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C9H11N5
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1
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| 1 |
Ki = 17000 nM
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CP0422779
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4-[6-(cyclopentylamino)-9-methylpurin-8-yl]phenol
Show/Hide
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C17H19N5O
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1
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| 1 |
Ki = 17800 nM
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CP0374423
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9-(sec-Butyl)-9H-adenine
Show/Hide
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C9H13N5
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1
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| 1 |
Ki = 19000 nM
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CP0381984
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N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]benzamide
Show/Hide
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C20H16ClN5O
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1
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| 1 |
Ki > 20000 nM
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CP0387954
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ethyl 2-(2,2-dimethylpropyl)-6-[[4-(trifluoromethyl)benzoyl]amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C21H22F3N5O3
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1
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| 1 |
Ki > 20000 nM
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CP0395577
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N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C18H17ClF3N5O
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1
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| 1 |
Ki > 20000 nM
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CP0395578
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N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)benzamide
Show/Hide
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C13H10ClN5O
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1
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| 1 |
Ki > 20000 nM
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CP0395579
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N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)-4-methylbenzamide
Show/Hide
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C14H12ClN5O
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1
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| 1 |
Ki > 20000 nM
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CP0395580
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N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)-2-phenylacetamide
Show/Hide
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C14H12ClN5O
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1
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| 1 |
Ki > 20000 nM
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CP0395581
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N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]-2-phenylacetamide
Show/Hide
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C18H20ClN5O
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1
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| 1 |
Ki > 20000 nM
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CP0395582
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N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)benzamide
Show/Hide
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C15H14ClN5O
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1
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| 1 |
Ki > 20000 nM
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CP0395584
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N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)-4-(trifluoromethyl)benzamide
Show/Hide
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C16H13ClF3N5O
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1
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| 1 |
Ki > 20000 nM
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CP0395635
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N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)-4-(trifluoromethyl)benzamide
Show/Hide
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C14H9ClF3N5O
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1
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| 1 |
Ki > 20000 nM
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CP0395636
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N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]-2-phenylacetamide
Show/Hide
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C21H18ClN5O
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1
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| 1 |
Ki > 20000 nM
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CP0395637
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4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-amine
Show/Hide
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C6H6ClN5
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1
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| 1 |
Ki > 20000 nM
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CP0395638
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N-benzoyl-N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)benzamide
Show/Hide
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C20H14ClN5O2
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1
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| 1 |
Ki > 20000 nM
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CP0395639
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4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-amine
Show/Hide
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C13H12ClN5
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1
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| 1 |
Ki > 20000 nM
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CP0395640
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N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-methylbenzamide
Show/Hide
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C21H18ClN5O
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1
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| 1 |
Ki > 20000 nM
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CP0396085
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ethyl 2-(2,2-dimethylpropyl)-6-[(4-methylbenzoyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C21H25N5O3
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1
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| 1 |
Ki > 20000 nM
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CP0415742
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N-benzoyl-N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]benzamide
Show/Hide
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C24H22ClN5O2
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1
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| 1 |
Ki > 20000 nM
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CP0434004
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N-benzoyl-N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)benzamide
Show/Hide
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C22H18ClN5O2
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1
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| 1 |
Ki > 20000 nM
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CP0434009
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N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-fluorobenzamide
Show/Hide
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C20H15ClFN5O
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1
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| 1 |
Ki > 20000 nM
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CP0435750
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N-benzoyl-N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]benzamide
Show/Hide
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C27H20ClN5O2
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1
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| 1 |
Ki > 20000 nM
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CP0435754
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N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)-4-fluorobenzamide
Show/Hide
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C15H13ClFN5O
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1
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| 1 |
Ki > 20000 nM
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CP0435769
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N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C21H15ClF3N5O
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1
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| 1 |
Ki > 20000 nM
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CP0442950
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N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)-4-methylbenzamide
Show/Hide
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C16H16ClN5O
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1
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| 1 |
Ki > 20000 nM
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CP0442956
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N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)-4-fluorobenzamide
Show/Hide
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C13H9ClFN5O
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1
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| 1 |
Ki > 20000 nM
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CP0380638
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ethyl 6-(dibenzoylamino)-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C30H25N5O4
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1
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| 1 |
Ki > 20000 nM
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CP0386784
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ethyl 6-[(3,4-dichlorobenzoyl)amino]-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C23H19Cl2N5O3
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1
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| 1 |
Ki > 20000 nM
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CP0395503
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ethyl 6-[bis(3,4-difluorobenzoyl)amino]-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C23H15F4N5O4
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1
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| 1 |
Ki > 20000 nM
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CP0412827
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6-amino-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxamide
Show/Hide
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C7H8N6O
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1
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| 1 |
Ki > 20000 nM
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CP0418068
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6-amino-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxamide
Show/Hide
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C9H12N6O
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1
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| 1 |
Ki > 20000 nM
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CP0418069
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ethyl 6-benzamido-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C16H15N5O3
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1
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| 1 |
Ki > 20000 nM
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CP0418070
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ethyl 2-methyl-6-[[4-(trifluoromethyl)benzoyl]amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
|
C17H14F3N5O3
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1
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| 1 |
Ki > 20000 nM
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CP0418071
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ethyl 2-methyl-6-[(4-methylbenzoyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C17H17N5O3
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1
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| 1 |
Ki > 20000 nM
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CP0418072
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ethyl 6-[(4-methylbenzoyl)amino]-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
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C24H23N5O3
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1
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| 1 |
Ki > 20000 nM
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CP0418073
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ethyl 2-(2-phenylethyl)-6-[[4-(trifluoromethyl)benzoyl]amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
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C24H20F3N5O3
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1
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| 1 |
Ki > 20000 nM
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CP0418075
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6-amino-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxamide
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C14H14N6O
|
1
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| 1 |
Ki > 20000 nM
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CP0418076
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ethyl 6-[bis(4-bromobenzoyl)amino]-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
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C23H17Br2N5O4
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1
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| 1 |
Ki > 20000 nM
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CP0418077
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ethyl 6-[(4-bromobenzoyl)amino]-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
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C23H20BrN5O3
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1
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| 1 |
Ki > 20000 nM
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CP0431437
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ethyl 2-(2,2-dimethylpropyl)-6-[(2-phenylacetyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
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C21H25N5O3
|
1
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| 1 |
Ki > 20000 nM
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CP0446051
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6-amino-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidine-4-carboxamide
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C11H16N6O
|
1
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| 1 |
Ki > 20000 nM
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CP0448362
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ethyl 6-amino-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
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C9H11N5O2
|
1
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| 1 |
Ki > 20000 nM
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CP0448363
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ethyl 6-[(4-methylbenzoyl)amino]-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
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C19H21N5O3
|
1
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| 1 |
Ki > 20000 nM
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CP0448365
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ethyl 6-(dibenzoylamino)-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
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C25H23N5O4
|
1
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| 1 |
Ki > 20000 nM
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CP0448366
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ethyl 2-methyl-6-[(2-phenylacetyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
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C17H17N5O3
|
1
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| 1 |
Ki > 20000 nM
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CP0450090
|
ethyl 6-[(4-fluorobenzoyl)amino]-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
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C16H14FN5O3
|
1
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| 1 |
Ki > 20000 nM
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CP0453849
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ethyl 6-[(4-fluorobenzoyl)amino]-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
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C18H18FN5O3
|
1
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| 1 |
Ki > 20000 nM
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CP0459772
|
ethyl 2-propan-2-yl-6-[[4-(trifluoromethyl)benzoyl]amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C19H18F3N5O3
|
1
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| 1 |
Ki > 20000 nM
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CP0480605
|
ethyl 6-(dibenzoylamino)-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C23H19N5O4
|
1
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| 1 |
Ki > 20000 nM
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CP0481161
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ethyl 6-[(4-fluorobenzoyl)amino]-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C23H20FN5O3
|
1
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| 1 |
Ki > 20000 nM
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CP0544755
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ethyl 2-(2,2-dimethylpropyl)-6-[(4-fluorobenzoyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C20H22FN5O3
|
1
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| 1 |
Ki > 20000 nM
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CP0043620
|
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
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C8H10N4O2
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2
|
| 1 |
Ki = 20500 nM
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| 2 |
Ki = 33800 nM
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CP0155498
|
2-CI Adenosine
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C10H12ClN5O4
|
1
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| 1 |
Ki = 21400 nM
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CP0044933
|
9-Benzyl-9H-adenine
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C12H11N5
|
1
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| 1 |
Ki > 30000 nM
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CP0065980
|
9-Ethyl-9H-adenine
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C7H9N5
|
1
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| 1 |
Ki > 30000 nM
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CP0135358
|
(S)-DHPA
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C8H11N5O2
|
1
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| 1 |
Ki > 30000 nM
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CP0219570
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9-METHYL-9H-PURIN-6-AMINE
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C6H7N5
|
1
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| 1 |
Ki > 30000 nM
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CP0228381
|
2-(6-Amino-purin-9-yl)-ethanol
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C7H9N5O
|
1
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| 1 |
Ki > 30000 nM
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CP0374393
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7-Ethyl-7H-adenine
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C7H9N5
|
1
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| 1 |
Ki > 30000 nM
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CP0374425
|
9-Phenethyladenine
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C13H13N5
|
1
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| 1 |
Ki > 30000 nM
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CP0381883
|
9-(2-Hydroxypropyl)-9H-adenine
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C8H11N5O
|
1
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| 1 |
Ki > 30000 nM
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CP0381884
|
9-Benzyl-8-bromo-9H-adenine
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C12H10BrN5
|
1
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| 1 |
Ki > 30000 nM
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CP0381885
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8-Bromo-9-phenylethyl-9H-adenine
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C13H12BrN5
|
1
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| 1 |
Ki > 30000 nM
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CP0381887
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9-But-3-enyl-9H-adenine
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C9H11N5
|
1
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| 1 |
Ki > 30000 nM
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CP0381891
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7-(3-Hydroxypropyl)-7H-adenine
Show/Hide
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C8H11N5O
|
1
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| 1 |
Ki > 30000 nM
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CP0381893
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7-Methyl-7H-adenine
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C6H7N5
|
1
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| 1 |
Ki > 30000 nM
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CP0381895
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9-Isobutyl-9H-adenine
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C9H13N5
|
1
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| 1 |
Ki > 30000 nM
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CP0381897
|
9-Cyclohexyl-9H-adenine
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C11H15N5
|
1
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| 1 |
Ki > 30000 nM
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CP0381898
|
8-Bromo-9-cyclohexyl-9H-adenine
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C11H14BrN5
|
1
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| 1 |
Ki > 30000 nM
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CP0386726
|
9-Cyclopropyl-9H-adenine
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C8H9N5
|
1
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| 1 |
Ki > 30000 nM
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CP0386727
|
7-(sec-Butyl)-7H-adenine
Show/Hide
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C9H13N5
|
1
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| 1 |
Ki > 30000 nM
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CP0399762
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8-Bromo-9-(but-3-enyl)-9H-adenine
Show/Hide
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C9H10BrN5
|
1
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| 1 |
Ki > 30000 nM
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CP0399763
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7-(2-Hydroxyethyl)-7H-adenine
Show/Hide
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C7H9N5O
|
1
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| 1 |
Ki > 30000 nM
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CP0399764
|
7-(2,3-Dihydroxypropyl)-7H-adenine
Show/Hide
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C8H11N5O2
|
1
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| 1 |
Ki > 30000 nM
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CP0417368
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7-(2-Hydroxypropyl)-7H-adenine
Show/Hide
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C8H11N5O
|
1
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| 1 |
Ki > 30000 nM
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CP0417372
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7-Isobutyl-7H-adenine
Show/Hide
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C9H13N5
|
1
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| 1 |
Ki > 30000 nM
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CP0431049
|
6-Amino-9-cyclopentyl-9H-purine
Show/Hide
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C10H13N5
|
1
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| 1 |
Ki > 30000 nM
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CP0431050
|
9-Cycloheptyl-9H-adenine
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C12H17N5
|
1
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| 1 |
Ki > 30000 nM
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CP0431051
|
9-Butyl-9H-adenine
Show/Hide
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C9H13N5
|
1
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| 1 |
Ki > 30000 nM
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CP0435152
|
8-Br-adenine
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C5H4BrN5
|
1
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| 1 |
Ki > 30000 nM
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CP0439344
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8-Bromo-9-cycloheptyl-9H-adenine
Show/Hide
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C12H16BrN5
|
1
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| 1 |
Ki > 30000 nM
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CP0467847
|
7-Propyl-7H-adenine
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C8H11N5
|
1
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| 1 |
Ki > 30000 nM
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CP0474947
|
9-(3-Hydroxypropyl)-9H-adenine
Show/Hide
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C8H11N5O
|
1
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| 1 |
Ki > 30000 nM
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CP0506270
|
7-Isopropyl-7H-adenine
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C8H11N5
|
1
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| 1 |
Ki > 30000 nM
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CP0390257
|
2-phenyl-N-[4-phenyl-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]acetamide
Show/Hide
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C28H23N7O
|
1
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| 1 |
Ki > 30000 nM
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CP0452425
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N-[4-(4-chlorophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C27H20ClN7O
|
1
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| 1 |
Ki > 30000 nM
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CP0473649
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N-[4-(4-fluorophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C28H22FN7O
|
1
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| 1 |
Ki > 30000 nM
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CP0484553
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N-[4-(4-fluorophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C27H20FN7O
|
1
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| 1 |
Ki > 30000 nM
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CP0504812
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N-[4-(4-chlorophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C28H22ClN7O
|
1
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| 1 |
Ki > 30000 nM
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CP0397159
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N-[5-[4-amino-6-(dimethylamino)-1,3,5-triazin-2-yl]-4-phenyl-1,3-thiazol-2-yl]-4-methylbenzamide
Show/Hide
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C22H21N7OS
|
1
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| 1 |
Ki > 30000 nM
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CP0405959
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N-[8-(furan-2-yl)-9-methylpurin-6-yl]-4-phenylbenzamide
Show/Hide
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C23H17N5O2
|
1
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| 1 |
Ki > 30000 nM
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CP0471646
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1-[8-(furan-2-yl)-9-methylpurin-6-yl]-3-(4-methylphenyl)urea
Show/Hide
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C18H16N6O2
|
1
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| 1 |
Ki > 30000 nM
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CP0375194
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2-(furan-2-yl)-5-[(4-methoxyphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C18H15N5O4
|
1
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| 1 |
Ki > 30000 nM
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CP0379818
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5-[(4-fluorophenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C17H12FN5O3
|
1
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| 1 |
Ki > 30000 nM
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CP0379819
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5-[(4-chlorophenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C17H12ClN5O3
|
1
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| 1 |
Ki > 30000 nM
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CP0379836
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5-(benzhydrylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C23H17N5O3
|
1
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| 1 |
Ki > 30000 nM
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CP0379845
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5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C19H17N5O5
|
1
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| 1 |
Ki > 30000 nM
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CP0379939
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ethyl 2-(furan-2-yl)-5-methylsulfanyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C13H12N4O3S
|
1
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| 1 |
Ki > 30000 nM
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CP0396865
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1-cyclohexyl-3-[8-(1-ethoxyethenyl)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidin-5-yl]urea
Show/Hide
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C20H24N6O3
|
1
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| 1 |
Ki > 30000 nM
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CP0396866
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5-(cyclohexylcarbamoylamino)-2-(furan-2-yl)-N-methyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C18H21N7O3
|
1
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| 1 |
Ki > 30000 nM
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CP0397027
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2-(furan-2-yl)-5-[(4-phenylphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
|
C23H17N5O3
|
1
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| 1 |
Ki > 30000 nM
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CP0411865
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ethyl 5-(benzhydrylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C25H21N5O3
|
1
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| 1 |
Ki > 30000 nM
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CP0411867
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ethyl 2-(furan-2-yl)-5-[(2-phenylacetyl)amino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C20H17N5O4
|
1
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| 1 |
Ki > 30000 nM
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CP0414331
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5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C27H26N6O4
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1
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| 1 |
Ki > 30000 nM
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CP0463445
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5-(cyclohexylcarbamoylamino)-2-(furan-2-yl)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C25H27N7O3
|
1
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| 1 |
Ki > 30000 nM
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CP0480186
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2-(furan-2-yl)-5-(phenylcarbamoylamino)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C25H21N7O3
|
1
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| 1 |
Ki > 30000 nM
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CP0487929
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5-(cyclohexylcarbamoylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C17H18N6O4
|
1
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| 1 |
Ki > 30000 nM
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CP0494517
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ethyl 2-(furan-2-yl)-5-[(4-phenylphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C25H21N5O3
|
1
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| 1 |
Ki > 30000 nM
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CP0508102
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2-(furan-2-yl)-5-[[4-(trifluoromethyl)phenyl]methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
|
C18H12F3N5O3
|
1
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| 1 |
Ki > 30000 nM
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CP0542206
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2-(furan-2-yl)-5-[(2-phenylacetyl)amino]-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C26H22N6O3
|
1
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| 1 |
Ki > 30000 nM
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CP0850611
|
N-phenethyl-9-propyl-9H-purin-6-amine
Show/Hide
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C16H19N5
|
1
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| 1 |
Ki > 30000 nM
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CP0853606
|
N2-(3-phenylpropyl)-9-propyl-9H-purine-2,6-diamine
Show/Hide
|
C17H22N6
|
1
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| 1 |
Ki > 30000 nM
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CP0902366
|
N2-benzyl-9-propyl-9H-purine-2,6-diamine
Show/Hide
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C15H18N6
|
1
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| 1 |
Ki > 30000 nM
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CP0902367
|
N-benzyl-9-propyl-9H-purin-6-amine
Show/Hide
|
C15H17N5
|
1
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| 1 |
Ki > 30000 nM
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CP0946757
|
N-(3-phenylpropyl)-9-propyl-9H-purin-6-amine
Show/Hide
|
C17H21N5
|
1
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| 1 |
Ki > 30000 nM
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CP0393010
|
4-[6-(cyclopentylamino)-9-methylpurin-8-yl]benzoic acid
Show/Hide
|
C18H19N5O2
|
1
|
| 1 |
Ki > 30000 nM
|
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CP0393011
|
N-cyclopentyl-9-methyl-8-(4-methylphenyl)purin-6-amine
Show/Hide
|
C18H21N5
|
1
|
| 1 |
Ki > 30000 nM
|
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CP0393012
|
N-cyclopentyl-9-methyl-8-pyridin-3-ylpurin-6-amine
Show/Hide
|
C16H18N6
|
1
|
| 1 |
Ki > 30000 nM
|
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CP0393019
|
8-(2-chlorophenyl)-N-cyclopentyl-9-methylpurin-6-amine
Show/Hide
|
C17H18ClN5
|
1
|
| 1 |
Ki > 30000 nM
|
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CP0393022
|
N-cyclopentyl-9-methyl-8-(2-methylphenyl)purin-6-amine
Show/Hide
|
C18H21N5
|
1
|
| 1 |
Ki > 30000 nM
|
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CP0412437
|
N-cyclohexyl-9-methyl-8-phenylpurin-6-amine
Show/Hide
|
C18H21N5
|
1
|
| 1 |
Ki > 30000 nM
|
|
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CP0412438
|
N-cyclopentyl-8-(4-methoxyphenyl)-9-methylpurin-6-amine
Show/Hide
|
C18H21N5O
|
1
|
| 1 |
Ki > 30000 nM
|
|
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CP0478878
|
8-(4-chlorophenyl)-N-cyclopentyl-9-methylpurin-6-amine
Show/Hide
|
C17H18ClN5
|
1
|
| 1 |
Ki > 30000 nM
|
|
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CP0493562
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N-cyclopentyl-8-(4-fluorophenyl)-9-methylpurin-6-amine
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C17H18FN5
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1
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| 1 |
Ki > 30000 nM
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CP0386798
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2-(furan-2-yl)-5-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
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C17H20N6O5
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1
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| 1 |
Ki > 30000 nM
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CP0394632
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N-benzhydryl-5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C32H28N6O4
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1
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| 1 |
Ki > 30000 nM
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CP0394643
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ethyl 5-(2-aminoethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C14H16N6O3
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1
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| 1 |
Ki > 30000 nM
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CP0434929
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ethyl 2-(furan-2-yl)-5-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C19H24N6O5
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1
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| 1 |
Ki > 30000 nM
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CP0420984
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3-(4-methylphenyl)-8-(2-oxopropoxy)chromen-2-one
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C19H16O4
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1
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| 1 |
Ki > 30000 nM
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CP0420985
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8-(2-oxopropoxy)-3-phenylchromen-2-one
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C18H14O4
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1
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| 1 |
Ki > 30000 nM
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CP0477026
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3-(4-bromophenyl)-8-(2-oxopropoxy)chromen-2-one
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C18H13BrO4
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1
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| 1 |
Ki > 30000 nM
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CP0446517
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2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl-5-N-methylcarbamoyl-beta-D-ribofuranosyl)adenine
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C17H23ClN6O6
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1
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| 1 |
Ki = 30800 nM
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CP0448364
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ethyl 6-amino-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
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C16H17N5O2
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1
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| 1 |
Ki = 60000 nM
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CP0380867
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8-[[4-(3-imidazol-1-ylpropoxy)phenyl]methyl]-1,3-dimethyl-7H-purine-2,6-dione
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C20H22N6O3
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1
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| 1 |
Ki > 10 nM
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CP0380869
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1,3-dimethyl-8-[[4-(3-morpholin-4-ylpropoxy)phenyl]methyl]-7H-purine-2,6-dione
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C21H27N5O4
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1
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| 1 |
Ki > 10 nM
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CP0395277
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8-[[4-(3-chloropropoxy)phenyl]methyl]-1,3-dimethyl-7H-purine-2,6-dione
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C17H19ClN4O3
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1
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| 1 |
Ki > 10 nM
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CP0395278
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8-[4-(3-chloropropoxy)phenyl]-1,3-dimethyl-7H-purine-2,6-dione
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C16H17ClN4O3
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1
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| 1 |
Ki > 10 nM
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CP0431956
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8-[[4-[3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)propoxy]phenyl]methyl]-1,3-dimethyl-7H-purine-2,6-dione
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C24H31N5O5
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1
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| 1 |
Ki > 10 nM
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CP0348839
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1,3-dimethyl-8-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C20H23N5O2
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1
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| 1 |
Ki > 300 nM
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CP0420718
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1,3-dimethyl-8-(2-thiophen-2-ylethyl)-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C16H19N5O2S
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1
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| 1 |
Ki > 300 nM
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CP0424271
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8-[2-(2-fluorophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C18H20FN5O2
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1
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| 1 |
Ki > 300 nM
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CP0424284
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2-(1,3-dimethyl-2,4-dioxo-7,9-dihydro-6H-purino[7,8-a]pyrazin-8-yl)acetonitrile
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C12H14N6O2
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1
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| 1 |
Ki > 300 nM
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CP0430140
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8-(2,3-dihydro-1H-inden-1-yl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C19H21N5O2
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1
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| 1 |
Ki > 300 nM
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CP0430155
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8-[2-[2-fluoro-5-(trifluoromethyl)phenyl]ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C19H19F4N5O2
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1
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| 1 |
Ki > 300 nM
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CP0430353
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1,3-dimethyl-8-(2-phenoxyethyl)-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C18H21N5O3
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1
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| 1 |
Ki > 300 nM
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CP0451277
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1,3-dimethyl-8-(3-phenylpropyl)-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C19H23N5O2
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1
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| 1 |
Ki > 300 nM
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CP0468933
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8-[2-(3-bromophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C18H20BrN5O2
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1
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| 1 |
Ki > 300 nM
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CP0482663
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8-[2-(3-fluorophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C18H20FN5O2
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1
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| 1 |
Ki > 300 nM
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CP0482784
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8-[(1S)-2,3-dihydro-1H-inden-1-yl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C19H21N5O2
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1
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| 1 |
Ki > 300 nM
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CP0408997
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1,3-diethyl-9-[2-(4-hydroxyphenyl)ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C20H25N5O3
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1
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| 1 |
Ki > 500 nM
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CP0151608
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1-[2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-(4-methoxy-phenyl)-urea
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C30H24N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0376366
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1-[8-(2-benzyloxy-ethyl)-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-pyridin-3-yl-urea
Show/Hide
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C25H21N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0376368
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1-[8-(2-benzyloxy-ethyl)-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-pyridin-4-yl-urea
Show/Hide
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C25H21N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0394720
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1-[2-furan-2-yl-8-(2-hydroxy-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-pyridin-3-yl-urea
Show/Hide
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C18H15N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0408271
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1-[2-furan-2-yl-8-(2-hydroxy-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-pyridin-4-yl-urea
Show/Hide
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C18H15N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0449386
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5-[[(4-pyridyl)amino]carbonyl]amino-[8-(3-benzyloxypropyl)-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
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C26H23N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0453022
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1-[2-furan-2-yl-8-(3-hydroxy-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-pyridin-4-yl-urea
Show/Hide
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C19H17N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0224044
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ethyl N-[5-(4-chlorobenzoyl)-4-phenyl-1,3-thiazol-2-yl]carbamate
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C19H15ClN2O3S
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1
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| 1 |
Ki > 1000 nM
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CP0374010
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N-[5-(4-methylbenzoyl)-4-phenyl-1,3-thiazol-2-yl]benzamide
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C24H18N2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0375611
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(4-Chlorophenyl)(2-(methylamino)-4-phenylthiazol-5-yl)methanone
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C17H13ClN2OS
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1
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| 1 |
Ki > 1000 nM
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CP0375631
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(4-(Methylsulfonyl)phenyl)(4-phenyl-2-(phenylamino)-thiazol-5-yl)methanone
Show/Hide
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C23H18N2O3S2
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1
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| 1 |
Ki > 1000 nM
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CP0375632
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(4-Methoxyphenyl)(2-(methylamino)-4-phenylthiazol-5-yl)methanone
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C18H16N2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0381164
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(4-Methoxyphenyl)(4-phenyl-2-(phenylamino)thiazol-5-yl)methanone
Show/Hide
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C23H18N2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0381190
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(4-Phenyl-2-(phenylamino)thiazol-5-yl)(p-toluyl)methanone
Show/Hide
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C23H18N2OS
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1
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| 1 |
Ki > 1000 nM
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CP0382902
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N-[5-(4-methoxybenzoyl)-4-phenyl-1,3-thiazol-2-yl]benzamide
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C24H18N2O3S
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1
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| 1 |
Ki > 1000 nM
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CP0383231
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N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)furan-2-carboxamide
Show/Hide
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C21H14N2O3S
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1
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| 1 |
Ki > 1000 nM
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CP0383778
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N-[5-(4-chlorobenzoyl)-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C21H13ClN2O3S
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1
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| 1 |
Ki > 1000 nM
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CP0391203
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N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)benzamide
Show/Hide
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C23H16N2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0391226
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(2-(Methylamino)-4-phenylthiazol-5-yl)(phenyl)methanone
Show/Hide
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C17H14N2OS
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1
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| 1 |
Ki > 1000 nM
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CP0450401
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N-[5-(4-chlorobenzoyl)-4-phenyl-1,3-thiazol-2-yl]-4-methylbenzamide
Show/Hide
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C24H17ClN2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0450402
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N-[5-(4-methylsulfonylbenzoyl)-4-phenyl-1,3-thiazol-2-yl]benzamide
Show/Hide
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C24H18N2O4S2
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1
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| 1 |
Ki > 1000 nM
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CP0453056
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N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)-4-methylbenzamide
Show/Hide
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C24H18N2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0460997
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ethyl N-[5-(4-methoxybenzoyl)-4-phenyl-1,3-thiazol-2-yl]carbamate
Show/Hide
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C20H18N2O4S
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1
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| 1 |
Ki > 1000 nM
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CP0035607
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2-furan-2-yl-7-(2-{4-[4-(2-methoxy-ethoxy)-phenyl]-piperazin-1-yl}-ethyl)-2,7-dihydro-3H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C25H29N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0156252
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N-(4-oxo-3,1-benzothiazin-2-yl)-4-phenylbutanamide
Show/Hide
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C18H16N2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0307644
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2-(3-chlorophenoxy)-N-(4-oxo-3,1-benzothiazin-2-yl)acetamide
Show/Hide
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C16H11ClN2O3S
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1
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| 1 |
Ki > 1000 nM
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CP0375529
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N-methyl-N-(4-oxo-3,1-benzothiazin-2-yl)-4-phenylbutanamide
Show/Hide
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C19H18N2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0375530
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(E)-4-(3-methoxyphenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)but-3-enamide
Show/Hide
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C19H16N2O3S
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1
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| 1 |
Ki >= 1000 nM
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CP0375532
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3-(3,4-dichlorophenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)propanamide
Show/Hide
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C17H12Cl2N2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0375533
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4-[4-[(2-chlorophenyl)methyl]piperazine-1-carbonyl]-N-(4-oxo-3,1-benzothiazin-2-yl)benzamide
Show/Hide
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C27H23ClN4O3S
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1
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| 1 |
Ki > 1000 nM
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CP0375534
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N-(5,6-dimethyl-4-oxothieno[2,3-d][1,3]thiazin-2-yl)-4-phenylbutanamide
Show/Hide
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C18H18N2O2S2
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1
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| 1 |
Ki > 1000 nM
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CP0375535
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4-(3-chlorophenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)butanamide
Show/Hide
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C18H15ClN2O2S
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1
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| 1 |
Ki >= 1000 nM
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CP0375536
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3-(3-methoxyphenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)prop-2-ynamide
Show/Hide
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C18H12N2O3S
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1
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| 1 |
Ki > 1000 nM
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CP0375537
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N-(6-chloro-4-oxo-3,1-benzothiazin-2-yl)-4-phenylbutanamide
Show/Hide
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C18H15ClN2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0375538
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4-[4-[(4-chlorophenyl)methyl]piperazine-1-carbonyl]-N-(4-oxo-3,1-benzothiazin-2-yl)benzamide
Show/Hide
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C27H23ClN4O3S
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1
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| 1 |
Ki > 1000 nM
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CP0375539
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(E)-4-(3,4-dichlorophenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)but-3-enamide
Show/Hide
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C18H12Cl2N2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0375540
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(E)-4-(3-chlorophenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)but-3-enamide
Show/Hide
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C18H13ClN2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0375541
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3-(2-bromophenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)propanamide
Show/Hide
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C17H13BrN2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0420745
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(E)-3-(3-chlorophenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)prop-2-enamide
Show/Hide
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C17H11ClN2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0420748
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N-(7-chloro-4-oxo-3,1-benzothiazin-2-yl)-4-phenylbutanamide
Show/Hide
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C18H15ClN2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0420750
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4-[4-[(3-chlorophenyl)methyl]piperazine-1-carbonyl]-N-(4-oxo-3,1-benzothiazin-2-yl)benzamide
Show/Hide
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C27H23ClN4O3S
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1
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| 1 |
Ki > 1000 nM
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CP0509996
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4-(3,4-dichlorophenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)butanamide
Show/Hide
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C18H14Cl2N2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0515236
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N-(6-bromo-4-oxo-3,1-benzothiazin-2-yl)-4-phenylbutanamide
Show/Hide
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C18H15BrN2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0149040
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1,3-diethyl-9-(4-hydroxyphenyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C18H21N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0377515
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9-[4-[2-(dimethylamino)ethoxy]phenyl]-1,3-diethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C22H30N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0377516
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1,3-dimethyl-9-[2-[4-(2-piperidin-1-ylethoxy)phenyl]ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C25H34N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0377517
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1,3-dimethyl-8-[2-[4-(2-morpholin-4-ylethoxy)phenyl]ethyl]-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C24H32N6O4
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1
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| 1 |
Ki > 1000 nM
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CP0377519
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1,3-dimethyl-9-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C22H28N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0380044
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9-[4-[2-(dimethylamino)ethoxy]phenyl]-1,3-dipropyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C24H34N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0380046
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9-[4-(2-piperidin-1-ylethoxy)phenyl]-1,3-dipropyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C27H38N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0386366
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1,3-dimethyl-9-[4-(2-piperidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C23H30N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0386367
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1,3-dibutyl-9-[4-(2-morpholin-4-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C28H40N6O4
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1
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| 1 |
Ki > 1000 nM
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CP0398703
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1,3-dipropyl-9-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C26H36N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0398704
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1,3-dibutyl-9-(4-hydroxyphenyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C22H29N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0398705
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1,3-dibutyl-9-[4-[2-(diethylamino)ethoxy]phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C28H42N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0398706
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1,3-dibutyl-9-[4-(2-piperidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C29H42N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0398707
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9-[4-(2-morpholin-4-ylethoxy)phenyl]-1,3-dipropyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C26H36N6O4
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1
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| 1 |
Ki > 1000 nM
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CP0398709
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9-[4-[2-(diethylamino)ethoxy]phenyl]-1,3-dipropyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C26H38N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0408995
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1,3-dimethyl-9-[2-[4-(2-morpholin-4-ylethoxy)phenyl]ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C24H32N6O4
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1
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| 1 |
Ki > 1000 nM
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CP0408998
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1,3-dimethyl-9-[4-(2-morpholin-4-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C22H28N6O4
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1
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| 1 |
Ki > 1000 nM
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CP0415381
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9-[4-[2-(diethylamino)ethoxy]phenyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C22H30N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0419912
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8-[2-[4-[2-(dimethylamino)ethoxy]phenyl]ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C22H30N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0420489
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1,3-dimethyl-9-[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C24H32N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0420550
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1,3-dibutyl-9-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C28H40N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0420571
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9-[4-[2-(dimethylamino)ethoxy]phenyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C20H26N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0420572
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9-(4-hydroxyphenyl)-1,3-dipropyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C20H25N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0420574
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8-[2-(4-hydroxyphenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H21N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0420575
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1,3-diethyl-9-[2-[4-(2-morpholin-4-ylethoxy)phenyl]ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C26H36N6O4
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1
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| 1 |
Ki > 1000 nM
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CP0424770
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9-[2-[4-[2-(dimethylamino)ethoxy]phenyl]ethyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C22H30N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0424771
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8-[2-[4-[2-(diethylamino)ethoxy]phenyl]ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C24H34N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0450331
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9-[2-[4-[2-(diethylamino)ethoxy]phenyl]ethyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C24H34N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0451592
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1,3-dimethyl-8-[2-[4-(2-piperidin-1-ylethoxy)phenyl]ethyl]-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C25H34N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0473554
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1,3-dibutyl-9-[4-[2-(dimethylamino)ethoxy]phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C26H38N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0855330
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N-(4-chlorobenzyl)-2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
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C31H37ClN6O4
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1
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| 1 |
Ki > 1000 nM
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CP0855331
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2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(3-methoxybenzyl)acetamide
Show/Hide
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C34H44N6O5
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1
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| 1 |
Ki > 1000 nM
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CP0855332
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N-(3-chlorobenzyl)-2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
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C33H41ClN6O4
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1
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| 1 |
Ki > 1000 nM
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CP0860865
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2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(2-(pyridin-2-yl)ethyl)acetamide
Show/Hide
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C33H43N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0874393
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N-(4-chlorobenzyl)-2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
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C33H41ClN6O4
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1
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| 1 |
Ki > 1000 nM
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CP0883748
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2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(4-sulfamoylphenethyl)acetamide
Show/Hide
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C32H41N7O6S
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1
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| 1 |
Ki > 1000 nM
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CP0899450
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2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(4-fluorobenzyl)acetamide
Show/Hide
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C31H37FN6O4
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1
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| 1 |
Ki > 1000 nM
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CP0905419
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2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(4-sulfamoylphenethyl)acetamide
Show/Hide
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C34H45N7O6S
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1
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| 1 |
Ki > 1000 nM
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CP0906712
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N-(3-chlorobenzyl)-2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
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C31H37ClN6O4
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1
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| 1 |
Ki > 1000 nM
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CP0909486
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N-benzyl-2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)acetamide
Show/Hide
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C31H38N6O4
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1
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| 1 |
Ki > 1000 nM
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CP0944315
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2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(3-methoxybenzyl)acetamide
Show/Hide
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C32H40N6O5
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1
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| 1 |
Ki > 1000 nM
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CP0944325
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2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(4-fluorobenzyl)acetamide
Show/Hide
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C33H41FN6O4
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1
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| 1 |
Ki > 1000 nM
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CP0958744
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2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(2-(pyridin-2-yl)ethyl)acetamide
Show/Hide
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C31H39N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0855288
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(R/S)-N-[6-(1-Phenylethoxy)-2-(propylsulfanyl)pyrimidin-4-yl]acetamide
Show/Hide
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C17H21N3O2S
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1
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| 1 |
Ki > 1000 nM
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CP0855289
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(R/S)-N-[2-(Benzylsulfanyl)-6-(butan-2-yloxy)pyrimidin-4-yl]acetamide
Show/Hide
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C17H21N3O2S
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1
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| 1 |
Ki > 1000 nM
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CP0864899
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(R/S)-N-{2-[(1-Phenylethyl)sulfanyl]-6-propoxypyrimidin-4-yl}acetamide
Show/Hide
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C17H21N3O2S
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1
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| 1 |
Ki > 1000 nM
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CP0249403
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1,3-dimethyl-8-[[2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl]methyl]-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C21H19F3N6O2S
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1
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| 1 |
Ki > 1000 nM
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CP0249895
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8-[[2-(3-chlorophenyl)-1,3-thiazol-4-yl]methyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C20H19ClN6O2S
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1
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| 1 |
Ki > 1000 nM
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CP0349532
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8-[3-(3-bromophenyl)propyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C19H22BrN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0350215
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8-[[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C20H19ClN6O2S
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1
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| 1 |
Ki > 1000 nM
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CP0420719
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8-[3-(3-chlorophenyl)prop-2-ynyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C19H18ClN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0420721
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8-[2-(3,4-dimethoxyphenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C20H25N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0420722
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1,3-dimethyl-8-(2-pyrrol-1-ylethyl)-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C16H20N6O2
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1
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| 1 |
Ki > 1000 nM
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CP0420739
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1,3-dimethyl-8-[(2-thiophen-2-yl-1,3-thiazol-4-yl)methyl]-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H18N6O2S2
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1
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| 1 |
Ki > 1000 nM
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CP0420740
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8-(4-fluorophenyl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C16H16FN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0420741
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8-(1-benzylpiperidin-4-yl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C22H28N6O2
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1
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| 1 |
Ki > 1000 nM
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CP0420751
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8-(3-chlorophenyl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C16H16ClN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0424273
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1,3-dimethyl-8-phenyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C16H17N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0424281
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8-[2-(3,4-dichlorophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H19Cl2N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0424290
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1,3-dimethyl-8-naphthalen-1-yl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C20H19N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0430134
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1,3-dimethyl-8-[2-[3-(trifluoromethyl)phenyl]ethyl]-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C19H20F3N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0430135
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1,3-dimethyl-8-(2-phenylpropyl)-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C19H23N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0430137
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8-[2-(2,6-dichlorophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H19Cl2N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0430139
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8-[2-(3,4-dichlorophenoxy)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H19Cl2N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0430156
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8-[2-(2,3-dimethoxyphenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C20H25N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0430158
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8-[2-(4-chlorophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H20ClN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0430331
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1,3-dimethyl-8-(3-pyrrol-1-ylpropyl)-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C17H22N6O2
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1
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| 1 |
Ki > 1000 nM
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CP0430332
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8-[2-(1,3-benzodioxol-5-yl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C19H21N5O4
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1
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| 1 |
Ki > 1000 nM
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CP0430333
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1,3-dimethyl-8-(2-phenylethyl)-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H21N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0430337
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8-[2-(2,3-difluorophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H19F2N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0430354
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8-(3-imidazol-1-ylpropyl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C16H21N7O2
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1
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| 1 |
Ki > 1000 nM
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CP0430394
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8-[(2,5-dimethylpyrazol-3-yl)methyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C16H21N7O2
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1
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| 1 |
Ki > 1000 nM
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CP0430395
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1,3-dimethyl-8-[[5-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl]methyl]-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C22H21F3N6O2S
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1
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| 1 |
Ki > 1000 nM
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CP0430397
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8-(2-hydroxy-2-phenylethyl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H21N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0430398
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8-(4-chlorophenyl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C16H16ClN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0446691
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8-[3-(4-chlorophenyl)propyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C19H22ClN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0451268
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8-[2-(5-bromo-2-methoxyphenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C19H22BrN5O3
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1
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| 1 |
Ki > 1000 nM
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CP0451279
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8-[(2S)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C21H25N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0460569
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8-[2-(3-chlorophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H20ClN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0460574
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8-[[1-(4-chlorophenyl)triazol-4-yl]methyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C19H19ClN8O2
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1
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| 1 |
Ki > 1000 nM
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CP0460691
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8-(3-fluorophenyl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C16H16FN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0468932
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8-[2-(2-bromophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C18H20BrN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0468934
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8-[2-(3-methoxyphenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C19H23N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0468935
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8-[2-(2-fluorophenoxy)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C18H20FN5O3
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1
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| 1 |
Ki > 1000 nM
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CP0472946
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8-(2,3-dihydro-1H-inden-2-yl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C19H21N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0482665
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8-[(1R)-2,3-dihydro-1H-inden-1-yl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C19H21N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0482666
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8-[3-(3,4-dichlorophenyl)prop-2-ynyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C19H17Cl2N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0482772
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8-[3-(3-methoxyphenyl)prop-2-ynyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C20H21N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0483066
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8-[2-(2,4-dichlorophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H19Cl2N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0483081
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8-(3-methoxyphenyl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C17H19N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0494847
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8-[2-(2-chlorophenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H20ClN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0529561
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8-[2-(2-methoxyphenyl)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C19H23N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0530521
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8-(4-bromophenyl)-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C16H16BrN5O2
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1
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| 1 |
Ki > 1000 nM
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CP0532045
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8-[2-(3-fluorophenoxy)ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C18H20FN5O3
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1
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| 1 |
Ki > 1000 nM
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CP0534537
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8-[2-[4-chloro-2-(trifluoromethyl)phenyl]ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C19H19ClF3N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0345084
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8-benzyl-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
Show/Hide
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C17H19N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0368394
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8-[(3,4-dichlorophenyl)methyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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C17H17Cl2N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0099745
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4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole
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C16H18N2O2
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1
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| 1 |
Ki > 1000 nM
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CP0239657
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cyclopropyl-[4-(3-piperidin-1-ylpropoxy)phenyl]methanone
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C18H25NO2
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1
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| 1 |
Ki > 1000 nM
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CP0542598
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4-phenyl-7-(3-pyrrolidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
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C24H26N4O
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1
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| 1 |
Ki > 1000 nM
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CP0546064
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4-[4-(3-piperidin-1-ylpropoxy)phenyl]-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
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C25H28N4O
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1
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| 1 |
Ki > 1000 nM
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CP0551159
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7-(3-piperidin-1-ylpropoxy)-4-[4-(3-piperidin-1-ylpropoxy)phenyl]-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
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C33H43N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0551160
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2-amino-7-(3-piperidin-1-ylpropoxy)-4-[4-(3-piperidin-1-ylpropoxy)phenyl]indeno[1,2-d]pyrimidin-5-one
Show/Hide
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C33H41N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0551161
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4-phenyl-7-(3-piperidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
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C25H28N4O
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1
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| 1 |
Ki > 1000 nM
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CP0381289
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4-(furan-2-yl)-11-methyl-N-[[4-(trifluoromethyl)phenyl]methyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
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C19H14F3N7O
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1
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| 1 |
Ki > 3000 nM
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CP0381327
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N-[(3,4-dimethoxyphenyl)methyl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C20H19N7O3
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1
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| 1 |
Ki > 3000 nM
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CP0397424
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1-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]propan-2-ol
Show/Hide
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C14H15N7O2
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1
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| 1 |
Ki > 3000 nM
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CP0380866
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ethyl 5-(cyclobutylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C16H17N5O3
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1
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| 1 |
Ki > 3000 nM
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CP0394628
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benzyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H15N5O3
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1
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| 1 |
Ki > 3000 nM
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CP0411132
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propan-2-yl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C14H15N5O3
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1
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| 1 |
Ki > 3000 nM
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CP0477182
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2-(furan-2-yl)-5-(methylamino)-N-(2-methyl-1-phenylpropan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C21H22N6O2
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1
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| 1 |
Ki > 3000 nM
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CP0882748
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5-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-ylamino)pentyl-ammonium chloride
Show/Hide
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C16H21ClN8O
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1
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| 1 |
Ki > 3000 nM
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CP0930443
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4-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-ylamino)butyl-ammonium chloride
Show/Hide
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C15H19ClN8O
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1
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| 1 |
Ki > 3000 nM
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CP0943820
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[3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)propyl]carbamic acid tert-butyl ester
Show/Hide
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C19H24N8O3
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1
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| 1 |
Ki > 3000 nM
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CP0380530
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N-[(3,4-dichlorophenyl)methyl]-2-[1-methyl-3-methylsulfonyl-2-oxo-4-(2-phenylethyl)quinolin-6-yl]oxyacetamide
Show/Hide
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C28H26Cl2N2O5S
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2
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| 1 |
Ki > 5000 nM
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| 2 |
Ki > 7000 nM
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CP0386035
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N-(3-methoxypropyl)-2-[[3-methylsulfonyl-2-oxo-4-(2-phenylethyl)-1H-quinolin-6-yl]oxy]acetamide
Show/Hide
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C24H28N2O6S
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1
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| 1 |
Ki > 5000 nM
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