General Information of the Compound
Compound ID
CP0065980
Compound Name
9-Ethyl-9H-adenine
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Synonyms
(9-ethylpurin-6-yl)amine
2715-68-6
6-Amino-9-ethylpurine
9-Ethyl-9H-adenine
9-Ethyl-9H-purin-6-ylamine
9-Ethyladenine
9-ethyl adenine
9-ethyl-9h-purin-6-amine
9-ethylpurin-6-amine
9H-Purin-6-amine, 9-ethyl-
9H-Purin-6-amine,9-ethyl
9H-Purin-6-amine,9-ethyl-
AC1L189M
AC1Q4VHH
ACMC-1CJP6
Adenine, 9-ethyl-
Adenine, 9-ethyl- (8CI)
CHEMBL304009
CTK4F9170
DTXSID50181616
KS-000000ID
MUIPLRMGAXZWSQ-UHFFFAOYSA-N
MolPort-004-964-357
N9 -ethyladenine
N9-Ethyladenine
NSC 14580
NSC14580
SCHEMBL1924594
ZINC402896
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Structure
Formula
C7H9N5
Molecular Weight
163.184
Canonical SMILES
CCn1cnc2c(N)ncnc12
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InChI
InChI=1S/C7H9N5/c1-2-12-4-11-5-6(8)9-3-10-7(5)12/h3-4H,2H2,1H3,(H2,8,9,10)
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InChIKey
MUIPLRMGAXZWSQ-UHFFFAOYSA-N
CAS
2715-68-6
Physicochemical Property
logP
0.4284
Rotatable Bonds
1
Heavy Atom Count
12
Polar Areas
69.62
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
12

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 7
SID: 16935745
ChEMBL ID
CHEMBL304009
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00840, Adenosine receptor A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 7400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 7400 nM
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2200 nM
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 30000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 100000 nM
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( 9-Ethyl-9H-adenine )
Drug Name 9-Ethyl-9H-adenine
Target(s)
Adenosine A2a receptor (ADORA2A)
Inhibitor
Adenosine A1 receptor (ADORA1)
Inhibitor