General Information of the Compound
Compound ID
CP0379815
Compound Name
2-(furan-2-yl)-5-(pentylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
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Structure
Formula
C15H17N5O3
Molecular Weight
315.333
Canonical SMILES
CCCCCNc1ncc(C(O)=O)c2nc(nn12)-c1ccco1
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InChI
InChI=1S/C15H17N5O3/c1-2-3-4-7-16-15-17-9-10(14(21)22)13-18-12(19-20(13)15)11-6-5-8-23-11/h5-6,8-9H,2-4,7H2,1H3,(H,16,17)(H,21,22)
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InChIKey
IZOYRNZUKBFKMC-UHFFFAOYSA-N
Physicochemical Property
logP
2.6846
Rotatable Bonds
7
Heavy Atom Count
23
Polar Areas
105.55
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118707883
ChEMBL ID
CHEMBL3314917
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00840, Adenosine receptor A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 10400 nM
   TI
   LI
   LO
   TS
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 26900 nM
   TI
   LI
   LO
   TS
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 26300 nM
   TI
   LI
   LO
   TS