General Information of the Compound
Compound ID
CP0905419
Compound Name
2-(4-(2-(1,3-dibutyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(4-sulfamoylphenethyl)acetamide
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Structure
Formula
C34H45N7O6S
Molecular Weight
679.844
Canonical SMILES
CCCCn1c(=O)c2c(nc3n2CCCN3CCc2ccc(OCC(=O)NCCc3ccc(S(N)(=O)=O)cc3)cc2)n(CCCC)c1=O
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InChI
InChI=1S/C34H45N7O6S/c1-3-5-20-40-31-30(32(43)41(34(40)44)21-6-4-2)39-22-7-19-38(33(39)37-31)23-17-26-8-12-27(13-9-26)47-24-29(42)36-18-16-25-10-14-28(15-11-25)48(35,45)46/h8-15H,3-7,16-24H2,1-2H3,(H,36,42)(H2,35,45,46)
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InChIKey
VYOHUSOIZGQDAX-UHFFFAOYSA-N
Physicochemical Property
logP
2.7978
Rotatable Bonds
16
Heavy Atom Count
48
Polar Areas
163.55
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
11
Complexity
48

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145979590
ChEMBL ID
CHEMBL4278535
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS