General Information of the Compound
Compound ID
CP0397880
Compound Name
4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid 3-nitro-phenyl ester
    Show/Hide
Structure
Formula
C23H23N5O7S
Molecular Weight
513.532
Canonical SMILES
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(cc1)S(=O)(=O)Oc1cccc(c1)[N+]([O-])=O
    Show/Hide
InChI
InChI=1S/C23H23N5O7S/c1-3-12-26-21-19(22(29)27(13-4-2)23(26)30)24-20(25-21)15-8-10-18(11-9-15)36(33,34)35-17-7-5-6-16(14-17)28(31)32/h5-11,14H,3-4,12-13H2,1-2H3,(H,24,25)
    Show/Hide
InChIKey
HYYOGEHGCDIFER-UHFFFAOYSA-N
Physicochemical Property
logP
3.0492
Rotatable Bonds
9
Heavy Atom Count
36
Polar Areas
159.19
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
10
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 11420910
SID: 16517508
ChEMBL ID
CHEMBL266099
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 43 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 4300 nM
   TI
   LI
   LO
   TS