General Information of the Compound
Compound ID
CP0882747
Compound Name
2-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-ylamino)ethyl-ammonium chloride
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Structure
Formula
C13H15ClN8O
Molecular Weight
334.771
Canonical SMILES
Cl.Cn1cc2c(nc(NCCN)n3nc(-c4ccco4)nc23)n1
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InChI
InChI=1S/C13H14N8O.ClH/c1-20-7-8-10(18-20)17-13(15-5-4-14)21-12(8)16-11(19-21)9-3-2-6-22-9;/h2-3,6-7H,4-5,14H2,1H3,(H,15,17,18);1H
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InChIKey
LYNLNGFEBUUGKF-UHFFFAOYSA-N
Physicochemical Property
logP
1.0634
Rotatable Bonds
4
Heavy Atom Count
23
Polar Areas
112.09
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155536934
ChEMBL ID
CHEMBL4474394
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00840, Adenosine receptor A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2500 nM
   TI
   LI
   LO
   TS
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 756 nM
   TI
   LI
   LO
   TS
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2400 nM
   TI
   LI
   LO
   TS