General Information of the Compound
Compound ID
CP0295149
Compound Name
(R)-N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-1-(3-(trifluoromethyl)phenylsulfonyl)pyrrolidine-3-carboxamide
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Structure
Formula
C24H25F3N4O5S2
Molecular Weight
570.615
Canonical SMILES
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)[C@@H]3CCN(C3)S(=O)(=O)c3cccc(c3)C(F)(F)F)sc12
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InChI
InChI=1S/C24H25F3N4O5S2/c1-4-31(14(2)32)18-8-9-19(36-3)20-21(18)37-23(28-20)29-22(33)15-10-11-30(13-15)38(34,35)17-7-5-6-16(12-17)24(25,26)27/h5-9,12,15H,4,10-11,13H2,1-3H3,(H,28,29,33)/t15-/m1/s1
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InChIKey
XOUCNJWVWYHRJZ-OAHLLOKOSA-N
Physicochemical Property
logP
4.3458
Rotatable Bonds
7
Heavy Atom Count
38
Polar Areas
108.91
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 54587015
ChEMBL ID
CHEMBL1760885
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 42 nM
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